Attenuation of Collagen-Induced Arthritis in 55-kDa TNF Receptor Type 1 (TNFR1)-IgG1-Treated and TNFR1-Deficient Mice

Journal of Immunology

Volumn 157, Issue 7, 1996, Pages 3178-3182

  Mori, Lucia ^a,c   Iselin, Sabine ^b   De Libero, Gennaro ^a   Lesslauer, Werner ^c  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; HYBRID PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN HEAVY CHAIN; LENERCEPT; LEUKOCYTE ANTIGEN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 1;

ANIMAL; ARTHRITIS; ARTICLE; C57BL MOUSE; CHEMISTRY; CHIMERA; CROSS BREEDING; DBA MOUSE; DISEASE COURSE; DISEASE MODEL; DISEASE PREDISPOSITION; GENE TARGETING; GENETICS; IMMUNIZATION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; PASSIVE IMMUNIZATION; PATHOLOGY; PHYSIOLOGY; RHEUMATOID ARTHRITIS;

ANIMALS; ANTIGENS, CD; ARTHRITIS; ARTHRITIS, RHEUMATOID; BASE SEQUENCE; CHIMERA; COLLAGEN; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DISEASE SUSCEPTIBILITY; GENE TARGETING; IMMUNIZATION; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN GAMMA-CHAINS; IMMUNOGLOBULIN HEAVY CHAINS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECOMBINANT FUSION PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0030267786     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Courtenay, J. S., M. J. Dallman, A. D. Dayan, A. Martin, and B. Mosedale. 1980. Immunisation against heterologous type II collagen induces arthritis in mice. Nature 283:666.
2. Holmdahl, R., L. Klareskog, K. Rubin, J. Björk, G. Smedergard, R. Jonsson, and M. Andersson. 1986. Role of T lymphocytes in murine collagen induced arthritis. Agents Actions 19:295.
3. Wooley, P. H., H. S. Luthra, J. M. Stuart, and C. S. David. 1981. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (1 region) linkage and antibody correlates. J. Exp. Med. 154:688.
4. Wooley, P. H., H. S. Luthra, M. M. Griffiths, J. M. Stuart, A. Huse, and C. S. David. 1985. Type II collagen-induced arthritis in mice. IV. Variations in immunogenetic regulation provide evidence for multiple arthritogenic epitopes on the collagen molecule. J. Immunol. 135:2443.
5. Holmdahl, R., M. Karlsson, M. E. Andersson, L. Rask, and L. Andersson. 1989. Localization of a critical restriction site on the I-Aβ chain that determines susceptibility to collagen-induced arthritis in mice. Proc. Natl. Acad. Sci. USA 86: 9475.
6. Banerjee, S., T. M. Haqqi, H. S. Luthra, J. M. Stuart, and C. S. David. 1988. Possible role of Vβ T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J. Exp. Med. 167:832.
7. r): an inbred mouse strain with a massive deletion of T cell receptor Vβ genes. J. Exp. Med. 169:1903.
8. Mori, L., H. Loetscher, K. Kakimoto, H. Bluethmann, and M. Steinmetz. 1992. Expression of a transgenic T cell receptor β chain enhances collagen-induced arthritis. J. Exp. Med. 176:381.
9. Stuart, J. M., A. S. Townes, and A. H. Kang. 1984. Collagen autoimmune arthritis. Annu. Rev. Immunol. 2:199.
10. Williams, R. O., M. Feldmann, and R. N. Maini. 1992. Anti-tumor necrosis factor ameliorates joint disease in murine collagen-induced arthritis. Proc. Natl. Acad. Sci. USA 89:9784.
11. Wooley, P. H., J. Dutcher, M. B. Widmer, and S. Gillis. 1993. Influence of a recombinant human soluble tumor necrosis factor receptor Fc fusion protein on type II collagen-induced arthritis in mice. J. Immunol. 151:6602.
12. Piguet, P. F., G. E. Grau, C. Vesin, H. Loetscher, R. Gentz, and W. Lesslauer. 1992. Evolution of collagen arthritis in mice is arrested by treatment with anti-tumor necrosis factor (TNF) antibody or a recombinant soluble TNF receptor. Immunology 77:510.
13. Thorbecke, G. J., R. Shah, C. H. Leu, A. P. Kuruvilla, A. M. Hardison, and M. A. Palladino. 1992. Involvement of endogenous tumor necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice. Proc. Natl. Acad. Sci. USA 89:7375.
14. Maini, R. N., M. J. Elliott, F. M. Brennan, R. O. Williams, C. Q. Chu, E. Paleolog, P. J. Charles, P. T. Taylor, and M. Feldmann. 1995. Monoclonal anti-TNFα antibody as a probe of pathogenesis and therapy of rheumatoid disease. Immunol. Rev. 144:195.
15. Keffer, J., L. Probert, H. Cazlaris, S. Georgopoulos, E. Kaslaris, D. Kioussis, and G. Kollias. 1991. Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis. EMBO J. 10:4025.
16. Probert, L., D. Plows, G. Kontogeorgos, and G. Kollias. 1995. The type I interleukin-1 receptor acts in series with tumor necrosis factor (TNF) to induce arthritis in TNF-transgenic mice. Eur. J. Immunol. 25:1794.
17. Cheng, J., K. Turksen, Q.-C. Yu, H. Schreiber, M. Teng, and E. Fichs. 1992. Cachexia and graft-vs.-host-disease-type skin changes in keratin promoter-driven TNFα transgenic mice. Genes Dev. 6:1444.
18. Vassalli, P. 1992. The pathophysiology of tumor necrosis factors. Annu. Rev. Immunol. 10:411.
19. Engelmann, H., H. Holtmann, C. Brakebusch, S. Y. Avni, I. Sarov, Y. Nophar, E. Hadas, O. Leitner, and D. Wallach. 1990. Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. J. Biol. Chem. 265:14497.
20. Olsson, I., M. Lantz, E. Nilsson, C. Peetre, H. Thysell, A. Grubb, and G. Adolf. 1989. Isolation and characterisation of a tumor necrosis factor binding protein from urine. Eur. J. Haematol. 42:270.
21. Seckinger, P., E. Vey, G. Turcatti, P. Wingfield, and J. M. Dayer. 1990. Tumor necrosis factor inhibitor: purification, NH2-terminal amino acid sequence and evidence for anti-inflammatory and immunomodulatory activities. Eur. J. Immunol. 20:1167.
22. Loetscher, H. R., R. Gentz, M. Zulauf, A. Lustig, H. Tabuchi, E. J. Schlaeger, M. Brockhaus, H. Gallati, M. Manneberg, and W. Lesslauer. 1991. Recombinant 55kDa TNF receptor: stoichiometry of binding to TNFα and TNFβ and inhibition of TNF activity. J. Biol. Chem. 266:18324.
23. Peppel, K., D. Crawford, and B. Beutler. 1991. A tumor necrosis factor receptor IgG heavy chain chimeric protein as a bivalent antagonist of TNF activity. J. Exp. Med. 174:1483.
24. Ashkenazi, A., S. A. Marsters, D. J. Capon, S. M. Chamow, I. S. Figari, P. Pennica, D. V. Goeddel, M. A. Palladino, and D. H. Smith. 1991. Protection against endotoxic shock by a tumor necrosis factor receptor immunoadhesin. Proc. Natl. Acad. Sci. USA 38:10535.
25. Baker, D., D. Butler, B. J. Scallon, J. K. O'Neill, J. L. Turk, and M. Feldmann. 1994. Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor immunoglobulin fusion proteins. Eur. J. Immunol. 24:2040.
26. Lesslauer, W., H. Tabuchi, R. Gentz, M. Brockhaus, E. J. Schlaeger, G. Grau, P. F. Piguet, P. Pointaire, P. Vassalli, and H. R. Loetscher. 1991. Recombinant soluble TNF receptor proteins protect mice from LPS-induced lethality. Eur. J. Immunol. 21:2883.
27. Williams, R. O., J. Ghrayeb, M. Feldmann, and R. N. Maini. 1995. Successful therapy of collagen-induced arthritis with TNF receptor-IgG fusion protein and combination with anti-CD4. Immunology 84:433.
28. Rothe, J., W. Lesslauer, H. Lötscher, Y. Lang, P. Koebel, F. Köntgen, A. Althage, R. Zinkernagel, M. Steinmetz, and H. Bluethmann. 1993. Mice lacking the tumor necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 364:798.
29. Laird, P. W., A. Zijderveld, K. Linders, M. A. Rudnicki, R. Jaenisch, and A. Berns. 1991. Simplified mammalian DNA isolation procedure. Nucleic Acids Res. 19:4293.
30. Gallati, H., and I. Pracht. 1993. sTNFR-55-hg1 ELIBA: Validation of an Analytical Method for the Determination of the Recombinant Human sTNFR-55-hg1 Fusion Construct, Roche Research Report B-161′582 F. Hoffmann-La Roche, Basel, Switzerland.
31. Gallati, H., and I. Pracht. 1993. Anti-Human TNFR55-hg1-ELISA: Enzyme Immunological Assay for the Detection and Quantitative Determination of Human Antibodies Against the Human TNFR55-hg1 Construct: Test Validation,. Roche Research Report B-162′274, F. Hoffmann-La Roche, Basel, Switzerland.
32. Van Zee, K. J., L. L. Moldawer, H. S. A. Oldenburg, W. A. Thompson, S. A. Stackpole, W. J. Montegut, M. A. Rogy, C. Meschter, H. Gallati, C.-D. Schiller, W. F. Richter, H. Loetscher, A. Askenazi, S. M. Chamow, F. Wurm, S. Calvano, S. F. Lowry, and W. Lesslauer. 1996. Protection against lethal Escherichia coli bacteriemia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081. J. Immunol. 156:2221.
33. Bazzoni, F., and B. Beutler. 1995. How do tumor necrosis factor receptors work? J. Inflammation 45:221.
34. Brennan, F. M., R. N. Maini, and M. Feldmann. 1992. TNFα-a pivotal role in rheumatoid arthritis. Br. J. Rheumatol. 31:293.
35. Boissier, M.-C., G. Chiocchia, N. Bessis, J. Hajnal, G. Garotta, F. Nicoletti, and C. Fournier. 1995. Biphasic effect of interferon-γ in murine collagen-induced arthritis. Eur. J. Immunol. 25:1184.