Anti-inflammatory effects of 8-hydroxydeoxyguanosine in LPS-induced microglia activation: Suppression of STAT3-mediated intercellular adhesion molecule-1 expression

Experimental and Molecular Medicine

Volumn 38, Issue 4, 2006, Pages 417-427

  Dong, Hyun Kim ^a   Ik, Hyun Cho ^b   Hong, Sook Kim ^a   Joo, Eun Jung ^a   Ja, Eun Kim ^a   Kwang, Ho Lee ^c   Park, Taekyu ^c   Young, Mok Yang ^c   Seong, Seung Yong ^a   Ye, Sang Kyu ^a   Chung, Myung Hee ^a  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

8 hydroxydeoxyguanosine; Intercellular adhesion molecule 1; Microglia; Reactive oxygen species; STAT3 transcription factor; Toll like receptor 4

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CYTOKINE; GAMMA INTERFERON; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENCEPHALITIS; IMMUNOHISTOCHEMISTRY; INCUBATION TIME; INFLAMMATION; MALE; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

EID: 33748473783     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2006.49     Document Type: Article

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