8-Oxo-7,8-dihydro-2′-deoxyguanosine is not salvaged for DNA synthesis in human leukemic U937 cells

Free Radical Research

Volumn 40, Issue 5, 2006, Pages 461-466

  Kim, Ja Eun ^a   Chung, Myung Hee ^a  

^a Seoul National University College of Medicine   (South Korea)

Author keywords

8 dihydro 2 deoxyguanosine; 8 oxo 7; Oxidative stress; Salvage pathway

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 HYDROXYGUANINE; CELL DNA;

ARTICLE; CELL STRAIN U937; CONTROLLED STUDY; DNA SYNTHESIS; HUMAN; HUMAN CELL; ISOTOPE LABELING; LEUKEMIA CELL LINE; NUCLEIC ACID METABOLISM; NUCLEOTIDE METABOLISM; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; RADIOACTIVITY;

CELL LINE, TUMOR; DNA; DNA REPLICATION; GUANINE; HUMANS; LEUKEMIA; OXIDATIVE STRESS;

EID: 33645100111     PISSN: 10715762     EISSN: 10292470     Source Type: Journal    
DOI: 10.1080/10715760600570539     Document Type: Article

References (33)

1. Kasai, H. (1997) Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis Mutat Res, 387, pp. 147-163.
2. Moriya, M. (1993) Single-stranded shuttle phagemid for mutagenesis studies in mammalian cells: 8-Oxoguanine in DNA induces targeted G.C → T.A transversions in simian kidney cells Proc Natl Acad Sci USA, 90, pp. 1122-1126.
3. Koizume, S and Inoue, H and Kamiya, H and Ohtsuka, E. (1998) Neighboring base damage induced by permanganate oxidation of 8-oxoguanine in DNA Nucleic Acids Res, 26, pp. 3599-3607.
4. Aburatani, H and Hippo, Y and Ishida, T and Takashima, R and Matsuba, C and Kodama, T and Takao, M and Yasui, A and Yamamoto, K and Asano, M. (1997) Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue Cancer Res, 57, pp. 2151-2156.
5. Hazra, TK and Izumi, T and Maidt, L and Floyd, RA and Mitra, S. (1998) The presence of two distinct 8-oxoguanine repair enzymes in human cells: Their potential complementary roles in preventing mutation Nucleic Acids Res, 26, pp. 5116-5122.
6. Matsumoto, Y and Zhang, QM and Takao, M and Yasui, A and Yonei, S. (2001) Escherichia coli Nth and human hNTH1 DNA glycosylases are involved in removal of 8-oxoguanine from 8-oxoguanine/guanine mispairs in DNA Nucleic Acids Res, 29, pp. 1975-1981.
7. Reardon, JT and Bessho, T and Kung, HC and Bolton, PH and Sancar, A. (1997) In vitro repair of oxidative DNA damage by human nucleotide excision repair system: Possible explanation for neurodegeneration in xeroderma pigmentosum patients Proc Natl Acad Sci USA, 94, pp. 9463-9468.
8. Weimann, A and Riis, B and Poulsen, HE. (2004) Oligonucleotides in human urine do not contain 8-oxo-7,8-dihydrodeoxyguanosine Free Radic Biol Med, 36, pp. 1378-1382.
9. Bessho, T and Tano, K and Kasai, H and Ohtsuka, E and Nishimura, S. (1993) Evidence for two DNA repair enzymes for 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in human cells J Biol Chem, 268, pp. 19416 -19421
10. Kang, D and Nishida, J and Iyama, A and Nakabeppu, Y and Furuichi, M and Fujiwara, T and Sekiguchi, M and Takeshige, K. (1995) Intracellular localization of 8-oxo-dGTPase in human cells, with special reference to the role of the enzyme in mitochondria J Biol Chem, 270, pp. 14659-14665.
11. Mo, JY and Maki, H and Sekiguchi, M. (1992) Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: Sanitization of nucleotide pool Proc Natl Acad Sci USA, 89, pp. 11021-11025.
12. Sakumi, K and Furuichi, M and Tsuzuki, T and Kakuma, T and Kawabata, S and Maki, H and Sekiguchi, M. (1993) Cloning and expression of cDNA for a human enzyme that hydrolyzes 8-oxo-dGTP, a mutagenic substrate for DNA synthesis J Biol Chem, 268, pp. 23524-23530.
13. Ishibashi, T and Hayakawa, H and Sekiguchi, M. (2003) A novel mechanism for preventing mutations caused by oxidation of guanine nucleotides EMBO Rep, 4, pp. 479-483.
14. Hayakawa, H and Taketomi, A and Sakumi, K and Kuwano, M and Sekiguchi, M. (1995) Generation and elimination of 8-oxo-7,8-dihydro-2′-deoxyguanosine 5′-triphosphate, a mutagenic substrate for DNA synthesis, in human cells Biochemistry, 34, pp. 89-95.
15. Cooke, MS and Evans, MD and Dove, R and Rozalski, R and Gackowski, D and Siomek, A and Lunec, J and Olinski, R. (2005) DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine Mutat Res, 574, pp. 58-66.
16. Haghdoost, S and Czene, S and Naslund, I and Skog, S and Harms-Ringdahl, M. (2005) Extracellular 8-oxo-dG as a sensitive parameter for oxidative stress in vivo and in vitro Free Radic Res, 39, pp. 153-162.
17. Shigenaga, MK and Gimeno, CJ and Ames, BN. (1989) Urinary 8-hydroxy-2′-deoxyguanosine as a biological marker of in vivo oxidative DNA damage Proc Natl Acad Sci USA, 86, pp. 9697-9701.
18. Rozalski, R and Siomek, A and Gackowski, D and Foksinski, M and Gran, C and Klungland, A and Olinski, R. (2004) Diet is not responsible for the presence of several oxidatively damaged DNA lesions in mouse urine Free Radic Res, 38, pp. 1201-1205.
19. Foksinski, M and Rozalski, R and Guz, J and Ruszkowska, B and Sztukowska, P and Piwowarski, M and Klungland, A and Olinski, R. (2004) Urinary excretion of DNA repair products correlates with metabolic rates as well as with maximum life spans of different mammalian species Free Radic Biol Med, 37, pp. 1449-1454.
20. Aruoma, OI and Halliwell, B and Gajewski, E and Dizdaroglu, M. (1991) Copper-ion-dependent damage to the bases in DNA in the presence of hydrogen peroxide Biochem J, 273(Pt 3), pp. 601-604.
21. Soderlund, JC and Arner, ES. (1994) Mitochondrial versus cytosolic activities of deoxyribonucleoside salvage enzymes Adv Exp Med Biol, 370, pp. 201-204.
22. Neyts, J and Balzarini, J and Andrei, G and Chaoyong, Z and Snoeck, R and Zimmermann, A and Mertens, T and Karlsson, A and De Clercq, E. (1998) Intracellular metabolism of the N7-substituted acyclic nucleoside analog 2-amino-7-(1,3-dihydroxy-2-propoxymethyl)purine, a potent inhibitor of herpesvirus replication Mol Pharmacol, 53, pp. 157-165.
23. Zhu, C and Johansson, M and Permert, J and Karlsson, A. (1998) Enhanced cytotoxicity of nucleoside analogs by overexpression of mitochondrial deoxyguanosine kinase in cancer cell lines J Biol Chem, 273, pp. 14707 - 14711.
24. Stolk, JN and De Abreu, RA and Boerbooms, AM and de Koning, DG and de Graaf, R and Kerstens, PJ and van de Putte, LB. (1995) Purine enzyme activities in peripheral blood mononuclear cells: Comparison of a new non-radiochemical high-performance liquid chromatography procedure and a radiochemical thin-layer chromatography procedure J Chromatogr B Biomed Appl, 666, pp. 33-43.
25. Sampath, D and Plunkett, W. (2000) The role of c-Jun kinase in the apoptotic response to nucleoside analogue-induced DNA damage Cancer Res, 60, pp. 6408-6415.
26. Spasokoukotskaja, T and Sasvari-Szekely, M and Keszler, G and Albertioni, F and Eriksson, S and Staub, M. (1999) Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity Eur J Cancer, 35, pp. 1862-1867.
27. Hayakawa, H and Hofer, A and Thelander, L and Kitajima, S and Cai, Y and Oshiro, S and Yakushiji, H and Nakabeppu, Y and Kuwano, M and Sekiguchi, M. (1999) Metabolic fate of oxidized guanine ribonucleotides in mammalian cells Biochemistry, 38, pp. 3610-3614.
28. Arner, ES and Eriksson, S. (1995) Mammalian deoxyribonucleoside kinases Pharmacol Ther, 67, pp. 155- 186.
29. Van Rompay, AR and Johansson, M and Karlsson, A. (2000) Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases Pharmacol Ther, 87, pp. 189-198.
30. Van Rompay, AR and Johansson, M and Karlsson, A. (2003) Substrate specificity and phosphorylation of antiviral and anticancer nucleoside analogues by human deoxyribonucleoside kinases and ribonucleoside kinases Pharmacol Ther, 100, pp. 119-139.
31. Mao, C and Cook, WJ and Zhou, M and Federov, AA and Almo, SC and Ealick, SE. (1998) Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues Biochemistry, 37, pp. 7135-7146.
32. Bialkowski K. Metabolism of 8-oxoguanine derivative. PhD dissertation. Bydgoszcz, Poland: The Ludwik Rudygier Medical University; 1997.
33. Olinski, R and Gackowski, D and Rozalski, R and Foksinski, M and Bialkowski, K. (2003) Oxidative DNA damage in cancer patients: A cause or a consequence of the disease development? Mutat Res, 531, pp. 177-190.