-
1
-
-
4344698841
-
Technological advances in high-throughput screening
-
DOI 10.2165/00129785-200404040-00006
-
LIU B, LI S, HU J: Technological advances in high-throughput screening. Am. J. Pharmacogenomics (2004) 4:263-276. (Pubitemid 39145474)
-
(2004)
American Journal of PharmacoGenomics
, vol.4
, Issue.4
, pp. 263-276
-
-
Liu, B.1
Li, S.2
Hu, J.3
-
2
-
-
0348155858
-
New fluorescence techniques for high-throughput drug discovery
-
DOI 10.2174/1389201033377382
-
JAGER S, BRAND L, EGGELING C: New fluorescence techniques for highthroughput drug discovery. Curr. Pharm. Biotechnol. (2003) 4:463-476. (Pubitemid 38008723)
-
(2003)
Current Pharmaceutical Biotechnology
, vol.4
, Issue.6
, pp. 463-476
-
-
Jager, S.1
Brand, L.2
Eggeling, C.3
-
3
-
-
0037404468
-
Selection criteria for drug-like compounds
-
DOI 10.1002/med.10041
-
MUEGGE I: Selection criteria for drug-like compounds. Med. Res. Rev. (2003) 23:302-321. (Pubitemid 36457537)
-
(2003)
Medicinal Research Reviews
, vol.23
, Issue.3
, pp. 302-321
-
-
Muegge, I.1
-
4
-
-
0035289779
-
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
-
DOI 10.1016/S0169-409X(00)00129-0, PII S0169409X00001290
-
LIPINSKI CA, LOMBARDO F, DOMINY BW, FEENEY PJ: Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv. Drug Deliv. Rev. (2001) 46:3-26. (Pubitemid 33653411)
-
(2000)
Advanced Drug Delivery Reviews
, vol.46
, Issue.1-3
, pp. 3-26
-
-
Lipinski, C.A.1
Lombardo, F.2
Dominy, B.W.3
Feeney, P.J.4
-
5
-
-
0032888376
-
A compartmental absorption and transit model for estimating oral drug absorption
-
DOI 10.1016/S0378-5173(99)00147-7, PII S0378517399001477
-
YU LX, AMIDON GL: A compartmental absorption and transit model for estimating oral drug absorption. Int. J. Pharm. (1999) 186:119-125. (Pubitemid 29459038)
-
(1999)
International Journal of Pharmaceutics
, vol.186
, Issue.2
, pp. 119-125
-
-
Yu, L.X.1
Amidon, G.L.2
-
6
-
-
3242778534
-
A physiological model for the estimation of the fraction dose absorbed in humans
-
DOI 10.1021/jm030999b
-
WILLMANN S, SCHMITT W, KELDENICH J, LIPPERT J, DRESSMAN JB: A physiological model for the estimation of the fraction dose absorbed in humans. J. Med. Chem. (2004) 47:4022-4031. (Pubitemid 38970963)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.16
, pp. 4022-4031
-
-
Willmann, S.1
Schmitt, W.2
Keldenich, J.3
Lippert, J.4
Dressman, J.B.5
-
7
-
-
0344084044
-
A physiologic model for simulating gastrointestinal flow and drug absorption in rats
-
DOI 10.1023/B:PHAM.0000003373.72652.c0
-
WILLMANN S, SCHMITT W, KELDENICH J, DRESSMAN JB: A physiologic model for simulating gastrointestinal flow and drug absorption in rats. Pharm. Res. (2003) 20:1766-1771. (Pubitemid 37449449)
-
(2003)
Pharmaceutical Research
, vol.20
, Issue.11
, pp. 1766-1771
-
-
Willmann, S.1
Schmitt, W.2
Keldenich, J.3
Dressman, J.B.4
-
8
-
-
0036803219
-
Prediction of intestinal absorption: Comparative assessment of GASTROPLUS™ and IDEA™
-
DOI 10.1016/S0928-0987(02)00132-X, PII S092809870200132X
-
PARROTT N, LAVE T: Prediction of intestinal absorption: comparative assessment of Gastroplus and Idea. Eur. J. Pharm. Sci. (2002) 17:51-61. (Pubitemid 35287171)
-
(2002)
European Journal of Pharmaceutical Sciences
, vol.17
, Issue.1-2
, pp. 51-61
-
-
Parrott, N.1
Lave, T.2
-
9
-
-
0035666579
-
Multilamellar liposomes and solid-supported lipid membranes (TRANSIL): Screening of lipid-water partitioning toward a high-throughput scale
-
DOI 10.1023/A:1013343117979
-
LOIDL-STAHLHOFEN A, HARTMANN T, SCHOTTNER M et al.: Multilamellar liposomes and solidsupported lipid membranes (TRANSIL): screening of lipid-water partitioning toward a high-throughput scale. Pharm. Res. (2001) 18:1782-1788. (Pubitemid 34020437)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.12
, pp. 1782-1788
-
-
Loidl-Stahlhofen, A.1
Hartmann, T.2
Schottner, M.3
Rhoring, C.4
Brodowsky, H.5
Schmitt, J.6
Keldenich, J.7
-
10
-
-
0035035820
-
Solid-supported lipid membranes as a tool for determination of membrane affinity: High-throughput screening of a physicochemical parameter
-
DOI 10.1002/1520-6017(200105)90:5<599::AID-JPS1016>3.0.CO;2-N
-
LOIDL-STAHLHOFEN A, ECKERT A, HARTMANN T, SCHOTTNER M: Solid-supported lipid membranes as a tool for determination of membrane affinity: high-throughput screening of a physicochemical parameter. J. Pharm. Sci. (2001) 90:599-606. (Pubitemid 32378381)
-
(2001)
Journal of Pharmaceutical Sciences
, vol.90
, Issue.5
, pp. 599-606
-
-
Loidl-Stahlhofen, A.1
Eckert, A.2
Hartmann, T.3
Schttner, M.4
-
11
-
-
0036075799
-
Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition
-
DOI 10.1002/jps.10128
-
POULIN P, THEIL FP: Prediction of pharmacokinetics prior to in vivo studies. II. Generic physiologically based pharmacokinetic models of drug disposition. J. Pharm. Sci. (2002) 91:1358-1370. (Pubitemid 34651198)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.5
, pp. 1358-1370
-
-
Poulin, P.1
Theil, F.-P.2
-
12
-
-
0036144815
-
Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution
-
DOI 10.1002/jps.10005
-
POULIN P, THEIL FP: Prediction of pharmacokinetics prior to in vivo studies. 1. Mechanism-based prediction of volume of distribution. J. Pharm. Sci. (2002) 91:129-156. (Pubitemid 34074473)
-
(2002)
Journal of Pharmaceutical Sciences
, vol.91
, Issue.1
, pp. 129-156
-
-
Poulin, P.1
Theil, F.-P.2
-
13
-
-
0035044107
-
Prediction of adipose tissue: Plasma partition coefficients for structurally unrelated drugs
-
POULIN P, SCHOENLEIN K, THEIL FP: Prediction of adipose tissue: plasma partition coefficients for structurally unrelated drugs. J. Pharm. Sci. (2001) 90:436-447.
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 436-447
-
-
Poulin, P.1
Schoenlein, K.2
Theil, F.P.3
-
14
-
-
0033966128
-
A priori prediction of tissue: Plasma partition coefficients of drugs to facilitate the use of physiologically-based pharmacokinetic models in drug discovery
-
DOI 10.1002/(SICI)1520-6017(200001)89:1<16::AID-JPS3>3.0.CO;2-E
-
POULIN P, THEIL FP: A priori prediction of tissue: plasma partition coefficients of drugs to facilitate the use of physiologicallybased pharmacokinetic models in drug discovery. J. Pharm. Sci. (2000) 89:16-35. (Pubitemid 30080151)
-
(2000)
Journal of Pharmaceutical Sciences
, vol.89
, Issue.1
, pp. 16-35
-
-
Poulin, P.1
Theil, F.-P.2
-
15
-
-
80052113647
-
-
NC Nicolau, R Hanko, W Hartwig (Eds), Wiley VCH, Weinheim, Germany
-
HÄRTER MW, KELDENICH J, SCHMITT W: In:Combinatorial Chemistry - A Practical Handbook, Part IV. NC Nicolau, R Hanko, W Hartwig (Eds), Wiley VCH, Weinheim, Germany (2002).
-
(2002)
Combinatorial Chemistry - A Practical Handbook, Part IV
-
-
Härter, M.W.1
Keldenich, J.2
Schmitt, W.3
-
16
-
-
2342635206
-
Application of high-performance liquid chromatography based measurements of lipophilicity to model biological distribution
-
DOI 10.1016/j.chroma.2003.10.084, PII S0021967303019095
-
VALKO K: Application of highperformance liquid chromatography based measurements of lipophilicity to model biological distribution. J. Chromatogr. A (2004) 1037:299-310. (Pubitemid 38591346)
-
(2004)
Journal of Chromatography A
, vol.1037
, Issue.1-2
, pp. 299-310
-
-
Valko, K.1
-
17
-
-
0036238280
-
A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential
-
DOI 10.1016/S0223-5234(02)01360-0, PII S0223523402013600
-
ZHU C, JIANG L, CHEN TM, HWANG KK: A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential. Eur. J. Med. Chem. (2002) 37:399-407. (Pubitemid 34465549)
-
(2002)
European Journal of Medicinal Chemistry
, vol.37
, Issue.5
, pp. 399-407
-
-
Zhu, C.1
Jiang, L.2
Chen, T.-M.3
Hwang, K.-K.4
-
18
-
-
0003573815
-
-
Physical Facts and Function D Chapman (Ed.), Academic Press, London
-
ROUSER G, NELSON J, FLEISCHER S, SIMON G: In:Biological Membranes, Vol 1: Physical Facts and Function. D Chapman (Ed.), Academic Press, London (1968).
-
(1968)
Biological Membranes
, vol.1
-
-
Rouser, G.1
Nelson, J.2
Fleischer, S.3
Simon, G.4
-
19
-
-
0028955162
-
Comparative investigation of lipid and fatty acid composition of fish gills and mammalian lungs. A model of the membrane lipid component areas
-
ZABELINSKII SA, BROVTSYNA NB, CHEBOTAREVA MA, GORBUNOVA OB, KRIVCHENKO AI: Comparative investigation of lipid and fatty acid composition of fish gills and mammalian lungs. A model of the membrane lipid component areas. Comp Biochem. Physiol B Biochem. Mol. Biol. (1995) 111:127-140.
-
(1995)
Comp Biochem. Physiol B Biochem. Mol. Biol.
, vol.111
, pp. 127-140
-
-
Zabelinskii, S.A.1
Brovtsyna, N.B.2
Chebotareva, M.A.3
Gorbunova, O.B.4
Krivchenko, A.I.5
-
20
-
-
0032518454
-
A general pattern for substrate recognition by P-glycoprotein
-
DOI 10.1046/j.1432-1327.1998.2510252.x
-
SEELIG A: A general pattern for substrate recognition by P-glycoprotein. Eur. J. Biochem. (1998) 251:252-261. (Pubitemid 28081437)
-
(1998)
European Journal of Biochemistry
, vol.251
, Issue.1-2
, pp. 252-261
-
-
Seelig, A.1
-
22
-
-
80052112298
-
-
GastroPlus product information by Simulations Plus
-
http://www.simulations-plus.com/products/ gastro-plus.html GastroPlus product information by Simulations Plus 2005).
-
(2005)
-
-
-
23
-
-
80052125178
-
-
PK-Sim product information by Bayer Technology Services
-
http://www.pk-sim.com PK-Sim product information by Bayer Technology Services 2005
-
(2005)
-
-
-
24
-
-
80052119480
-
-
PK Map product information by Bayer Technology Services
-
http://www.pk-map.com PK-Map product information by Bayer Technology Services 2005
-
(2005)
-
-
-
25
-
-
80052104840
-
-
NIMBUS website
-
http://www.nimbus-biotechnology.com NIMBUS website 2005
-
(2005)
-
-
-
26
-
-
80052108684
-
-
iDEA product information by Lion Bioscience
-
http://www.lionbioscience.com/solutions/ e20380/e20496/index-eng.html iDEA product information by Lion Bioscience (2005)
-
(2005)
-
-
|