Lymphoblastoid cell lines differing in p53 status show clear differences in basal gene expression with minor changes after irradiation

Radiotherapy and Oncology

Volumn 80, Issue 2, 2006, Pages 236-249

  Zschenker, Oliver ^a   Borgmann, Kerstin ^a   Streichert, Thomas ^b   Meier, Ingo ^c   Wrona, Agnieszka ^a   Dikomey, Ekkehard ^a  

^a Laboratory of Radiobiology and Experimental Radiooncology   (Germany)

^b Institute of Clinical Chemistry

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

Affymetrix; Gene array; Gene expression profile; Industrial radiosensitivity; Prediction

Indexed keywords

CASP1 PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; DEOXYRIBONULEIC ACID BINDING PROTEIN 2; FUCA1 PROTEIN; PROTEIN; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; RAD51C PROTEIN; SESTRIN 1; UNCLASSIFIED DRUG; XERODERMA PIGMENTOSUM GROUP C PROTEIN;

APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GAMMA IRRADIATION; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL LINE; MICROARRAY ANALYSIS; MUTATION; PREDICTION; PRIORITY JOURNAL; RADIOSENSITIVITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; VALIDATION STUDY;

CELL LINE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENES, P53; HUMANS; LYMPHOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; RADIATION TOLERANCE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33748209645     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2006.07.019     Document Type: Article

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