-
3
-
-
0035850402
-
The continuing epidemics of obesity and diabetes in the United States
-
Mokdad AH, Bowman BA, Ford ES, et al. The continuing epidemics of obesity and diabetes in the United States. JAMA 2001; 286:1195-1200.
-
(2001)
JAMA
, vol.286
, pp. 1195-1200
-
-
Mokdad, A.H.1
Bowman, B.A.2
Ford, E.S.3
-
4
-
-
0032695482
-
Annual deaths attributable to obesity in the United States
-
Allison DB, Fontaine KR, Manson JE, et al. Annual deaths attributable to obesity in the United States. JAMA 1999; 283:1530-1538.
-
(1999)
JAMA
, vol.283
, pp. 1530-1538
-
-
Allison, D.B.1
Fontaine, K.R.2
Manson, J.E.3
-
5
-
-
30444456396
-
Midlife body mass index and hospitalization and mortality in older age
-
Yan LL, Daviglus ML, Liu K, et al. Midlife body mass index and hospitalization and mortality in older age. JAMA 2006; 295:190-198.
-
(2006)
JAMA
, vol.295
, pp. 190-198
-
-
Yan, L.L.1
Daviglus, M.L.2
Liu, K.3
-
7
-
-
17144385790
-
Excess deaths associated with underweight, overweight, and obesity
-
Flegal KM, Graubard BI, Williamson DF, Gail MH. Excess deaths associated with underweight, overweight, and obesity. JAMA 2005; 293:1861-1867.
-
(2005)
JAMA
, vol.293
, pp. 1861-1867
-
-
Flegal, K.M.1
Graubard, B.I.2
Williamson, D.F.3
Gail, M.H.4
-
8
-
-
17144430418
-
Secular trends in cardiovascular disease risk factors according to body mass index in US adults
-
Gregg EW, Cheng YJ, Cadwell BL, et al. Secular trends in cardiovascular disease risk factors according to body mass index in US adults. JAMA 2005; 293:1868-1874.
-
(2005)
JAMA
, vol.293
, pp. 1868-1874
-
-
Gregg, E.W.1
Cheng, Y.J.2
Cadwell, B.L.3
-
9
-
-
23044507658
-
Underweight, overweight, obesity, and excess deaths
-
Willett WC, Hu FB, Colditz GA, Manson JE. Underweight, overweight, obesity, and excess deaths. JAMA 2005; 294:551.
-
(2005)
JAMA
, vol.294
, pp. 551
-
-
Willett, W.C.1
Hu, F.B.2
Colditz, G.A.3
Manson, J.E.4
-
10
-
-
23044507658
-
Underweight, overweight, obesity, and excess deaths
-
Strickler HD, Hall C, Wylie-Rosett J, Rohan T. Underweight, overweight, obesity, and excess deaths. JAMA 2005; 294:551-552.
-
(2005)
JAMA
, vol.294
, pp. 551-552
-
-
Strickler, H.D.1
Hall, C.2
Wylie-Rosett, J.3
Rohan, T.4
-
11
-
-
23044488654
-
Underweight, overweight, obesity, and excess deaths
-
Ding EL. Underweight, overweight, obesity, and excess deaths. JAMA 2005; 294:552.
-
(2005)
JAMA
, vol.294
, pp. 552
-
-
Ding, E.L.1
-
12
-
-
0037010474
-
Selected major risk factors and global and regional burden of disease
-
Comparative Risk Assessment Collaborating Group
-
Ezzati M, Lopez AD, Rodgers A, et al. Comparative Risk Assessment Collaborating Group, Selected major risk factors and global and regional burden of disease. Lancet 2002; 360:1347-1360.
-
(2002)
Lancet
, vol.360
, pp. 1347-1360
-
-
Ezzati, M.1
Lopez, A.D.2
Rodgers, A.3
-
13
-
-
20644442368
-
Overweight and obesity (high body mass index)
-
Ezzati M, Lopez AD, Rodgers A, Murray CJL, editors. Geneva: WHO
-
James WPT, Jackson-Leach R, Ni Mhurchu C, et al. Overweight and obesity (high body mass index). In: Ezzati M, Lopez AD, Rodgers A, Murray CJL, editors. Comparative quantification of health risks: global and regional burden of disease attributable to selected major risk factors, Vol. 1, Geneva: WHO; 2004. pp. 497-596.
-
(2004)
Comparative Quantification of Health Risks: Global and Regional Burden of Disease Attributable to Selected Major Risk Factors
, vol.1
, pp. 497-596
-
-
James, W.P.T.1
Jackson-Leach, R.2
Ni Mhurchu, C.3
-
14
-
-
20144363712
-
A potential decline in life expectancy in the United States in the 21st century
-
Olshansky SJ, Passaro DJ, Hershow RC, et al. A potential decline in life expectancy in the United States in the 21st century. N Engl J Med 2005; 352:1138-1145.
-
(2005)
N Engl J Med
, vol.352
, pp. 1138-1145
-
-
Olshansky, S.J.1
Passaro, D.J.2
Hershow, R.C.3
-
15
-
-
0035897696
-
Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
-
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285:2486-2497.
-
(2001)
JAMA
, vol.285
, pp. 2486-2497
-
-
-
16
-
-
0037021505
-
The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men
-
Lakka HM, Laaksonen DE, Lakka TA, et al. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002; 288:2709-2716.
-
(2002)
JAMA
, vol.288
, pp. 2709-2716
-
-
Lakka, H.M.1
Laaksonen, D.E.2
Lakka, T.A.3
-
17
-
-
4444329030
-
National Cholesterol Education Program vs. World Health Organization metabolic syndrome in relation to all cause and cardiovascular mortality in San Antonio Heart Study
-
Hunt KJ, Resendez WK, Haffner SM, Stern MP. National Cholesterol Education Program vs. World Health Organization metabolic syndrome in relation to all cause and cardiovascular mortality in San Antonio Heart Study. Circulation 2004; 110:1251-1257.
-
(2004)
Circulation
, vol.110
, pp. 1251-1257
-
-
Hunt, K.J.1
Resendez, W.K.2
Haffner, S.M.3
Stern, M.P.4
-
18
-
-
0042266224
-
Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies
-
Meigs JB, Wilson PW, Nathan DM, et al. Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies. Diabetes 2003; 52:2160-2167.
-
(2003)
Diabetes
, vol.52
, pp. 2160-2167
-
-
Meigs, J.B.1
Wilson, P.W.2
Nathan, D.M.3
-
19
-
-
32044453773
-
Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute scientific statement
-
Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: An American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Curr Opin Cardiol 2006;21:1-6.
-
(2006)
Curr Opin Cardiol
, vol.21
, pp. 1-6
-
-
Grundy, S.M.1
Cleeman, J.I.2
Daniels, S.R.3
-
20
-
-
0042665536
-
Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study
-
Sattar N, Gaw A, Scherbakova O, et al. Metabolic syndrome with and without C-reactive protein as a predictor of coronary heart disease and diabetes in the West of Scotland Coronary Prevention Study. Circulation 2003; 108:414-419.
-
(2003)
Circulation
, vol.108
, pp. 414-419
-
-
Sattar, N.1
Gaw, A.2
Scherbakova, O.3
-
21
-
-
4444222221
-
Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults
-
Malik S, Wong ND, Franklin SS, et al. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults. Circulation 2004; 110:1245-1250.
-
(2004)
Circulation
, vol.110
, pp. 1245-1250
-
-
Malik, S.1
Wong, N.D.2
Franklin, S.S.3
-
22
-
-
0346962890
-
The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS)
-
Girman CJ, Rhodes T, Mercuri M, et al. The metabolic syndrome and risk of major coronary events in the Scandinavian Simvastatin Survival Study (4S) and the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS). Am J Cardiol 2004; 93:136-141.
-
(2004)
Am J Cardiol
, vol.93
, pp. 136-141
-
-
Girman, C.J.1
Rhodes, T.2
Mercuri, M.3
-
23
-
-
0842277242
-
Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition
-
Grundy SM, Brewer HB Jr, Cleeman JI, et al. Definition of metabolic syndrome: report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation 2004; 109:433-438.
-
(2004)
Circulation
, vol.109
, pp. 433-438
-
-
Grundy, S.M.1
Brewer Jr., H.B.2
Cleeman, J.I.3
-
24
-
-
30544433479
-
Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the US
-
Ford ES. Prevalence of the metabolic syndrome defined by the International Diabetes Federation among adults in the US. Diabetes Care 2005; 28:2745-2749.
-
(2005)
Diabetes Care
, vol.28
, pp. 2745-2749
-
-
Ford, E.S.1
-
25
-
-
4444382796
-
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): Case-control study
-
Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study. Lancet 2004; 364:937-952.
-
(2004)
Lancet
, vol.364
, pp. 937-952
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
-
26
-
-
27644457743
-
Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: A case-control study
-
INTERHEART Study Investigators
-
Yusuf S, Hawken S, Ounpuu S, et al. INTERHEART Study Investigators. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 2005; 366:1640-1649. Case-control study of over 27 000 patients in 52 countries assessing which measure of obesity is the best predictor of myocardial infarction. The waist-to-hip ratio showed the strongest relation with the risk of myocardial infarction compared to BMI, waist and hip measurements across both sexes, all ages and ethnic groups.
-
(2005)
Lancet
, vol.366
, pp. 1640-1649
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
-
27
-
-
0036637538
-
Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: The San Antonio Heart Study
-
Hanley AJ, Williams K, Stern MP, Haffner SM. Homeostasis model assessment of insulin resistance in relation to the incidence of cardiovascular disease: the San Antonio Heart Study. Diabetes Care 2002; 25:1177-1184.
-
(2002)
Diabetes Care
, vol.25
, pp. 1177-1184
-
-
Hanley, A.J.1
Williams, K.2
Stern, M.P.3
Haffner, S.M.4
-
28
-
-
0034709065
-
Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: The Kuopio Ischaemic Heart Disease Risk Factor Study
-
Lakka HM, Lakka TA, Tuomilehto J, et al. Hyperinsulinemia and the risk of cardiovascular death and acute coronary and cerebrovascular events in men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Arch Intern Med 2000; 160:1160-1168.
-
(2000)
Arch Intern Med
, vol.160
, pp. 1160-1168
-
-
Lakka, H.M.1
Lakka, T.A.2
Tuomilehto, J.3
-
29
-
-
0035985223
-
Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death
-
Hedblad B, Nilsson P, Engström G, et al. Insulin resistance in non-diabetic subjects is associated with increased incidence of myocardial infarction and death. Diabet Med 2002; 19:470-475.
-
(2002)
Diabet Med
, vol.19
, pp. 470-475
-
-
Hedblad, B.1
Nilsson, P.2
Engström, G.3
-
30
-
-
0029862973
-
Hyperinsulinemia as an independent risk factor for ischemic heart disease
-
Després JP, Lamarche B, Mauriege P, et al. Hyperinsulinemia as an independent risk factor for ischemic heart disease. N Engl J Med 1996; 334:952-957.
-
(1996)
N Engl J Med
, vol.334
, pp. 952-957
-
-
Després, J.P.1
Lamarche, B.2
Mauriege, P.3
-
31
-
-
2542507751
-
Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men
-
Lempiäinen P, Mykkänen L, Pyörälä K, et al. Insulin resistance syndrome predicts coronary heart disease events in elderly nondiabetic men. Circulation 1999; 100:123-128.
-
(1999)
Circulation
, vol.100
, pp. 123-128
-
-
Lempiäinen, P.1
Mykkänen, L.2
Pyörälä, K.3
-
32
-
-
4143135494
-
Plasma insulin and cardiovascular mortality in non-diabetic European men and women: A meta-analysis of data from eleven prospective studies
-
Hu G, Qiao Q, Tuomilehto J, et al., DECODE Insulin Study Group. Plasma insulin and cardiovascular mortality in non-diabetic European men and women: a meta-analysis of data from eleven prospective studies. Diabetologia 2004; 47:1245-1256.
-
(2004)
Diabetologia
, vol.47
, pp. 1245-1256
-
-
Hu, G.1
Qiao, Q.2
Tuomilehto, J.3
-
33
-
-
2342506538
-
Relationship to insulin resistance of the Adult Treatment Panel III diagnostic criteria for identification of the metabolic syndrome
-
Cheal KL, Abbasi F, Lamendola C, et al. Relationship to insulin resistance of the Adult Treatment Panel III diagnostic criteria for identification of the metabolic syndrome. Diabetes 2004; 53:1195-1200.
-
(2004)
Diabetes
, vol.53
, pp. 1195-1200
-
-
Cheal, K.L.1
Abbasi, F.2
Lamendola, C.3
-
34
-
-
0242363615
-
Identification of subjects with insulin resistance and β-cell dysfunction using alternative definitions of the metabolic syndrome
-
Hanley AJ, Wagenknecht LE, D'Agostino RB Jr, et al. Identification of subjects with insulin resistance and β-cell dysfunction using alternative definitions of the metabolic syndrome. Diabetes 2003; 52:2740-2747.
-
(2003)
Diabetes
, vol.52
, pp. 2740-2747
-
-
Hanley, A.J.1
Wagenknecht, L.E.2
D'Agostino Jr., R.B.3
-
35
-
-
0033552883
-
Atherosclerosis: An inflammatory disease
-
Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340:115-126.
-
(1999)
N Engl J Med
, vol.340
, pp. 115-126
-
-
Ross, R.1
-
36
-
-
0035908632
-
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
-
Pradhan AD, Manson JE, Rifai N, et al. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 2001; 286:327-334.
-
(2001)
JAMA
, vol.286
, pp. 327-334
-
-
Pradhan, A.D.1
Manson, J.E.2
Rifai, N.3
-
37
-
-
0034704893
-
C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
-
Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342:836-843.
-
(2000)
N Engl J Med
, vol.342
, pp. 836-843
-
-
Ridker, P.M.1
Hennekens, C.H.2
Buring, J.E.3
Rifai, N.4
-
38
-
-
0037469255
-
C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8 year follow up of 14,719 initially healthy American women
-
Ridker PM, Buring JE, Cook NR, Rifai N. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8 year follow up of 14,719 initially healthy American women. Circulation 2003; 107:391-397.
-
(2003)
Circulation
, vol.107
, pp. 391-397
-
-
Ridker, P.M.1
Buring, J.E.2
Cook, N.R.3
Rifai, N.4
-
39
-
-
0037417947
-
American Heart Association guide for improving cardiovascular health at the community level: A statement for public health practitioners, healthcare providers, and health policy makers from the American Heart Association Expert Panel on Population and Prevention Science
-
Pearson TA, Bazzarre TL, Daniels SR, et al. American Heart Association guide for improving cardiovascular health at the community level: a statement for public health practitioners, healthcare providers, and health policy makers from the American Heart Association Expert Panel on Population and Prevention Science. Circulation 2003; 107:645-651.
-
(2003)
Circulation
, vol.107
, pp. 645-651
-
-
Pearson, T.A.1
Bazzarre, T.L.2
Daniels, S.R.3
-
40
-
-
1842587885
-
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease
-
Danesh J, Wheeler JG, Hirschfield GM, et al. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 2004; 350:1387-1397.
-
(2004)
N Engl J Med
, vol.350
, pp. 1387-1397
-
-
Danesh, J.1
Wheeler, J.G.2
Hirschfield, G.M.3
-
41
-
-
0043025533
-
Adiponectin: More than just another fat cell hormone?
-
Chandran M, Phillips SA, Ciaraldi T. Adiponectin: more than just another fat cell hormone? Diabetes Care 2003; 26:2442-2450.
-
(2003)
Diabetes Care
, vol.26
, pp. 2442-2450
-
-
Chandran, M.1
Phillips, S.A.2
Ciaraldi, T.3
-
42
-
-
0037947306
-
Interpreting incomplete data in studies of diet and weight loss
-
Ware JH. Interpreting incomplete data in studies of diet and weight loss. N Engl J Med 2003; 348:2136-2137.
-
(2003)
N Engl J Med
, vol.348
, pp. 2136-2137
-
-
Ware, J.H.1
-
43
-
-
0038577223
-
Minireview: Adiposity, inflammation, and atherogenesis
-
Lyon CJ, Law RE, Hsueh WA. Minireview: adiposity, inflammation, and atherogenesis. Endocrinology 2003; 144:2195-2200.
-
(2003)
Endocrinology
, vol.144
, pp. 2195-2200
-
-
Lyon, C.J.1
Law, R.E.2
Hsueh, W.A.3
-
44
-
-
6944237757
-
Adipokines: Inflammation and the pleiotropic role of white adipose tissue
-
Trayhurn P, Wood IS. Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004; 92:347-355.
-
(2004)
Br J Nutr
, vol.92
, pp. 347-355
-
-
Trayhurn, P.1
Wood, I.S.2
-
45
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001; 86:1930-1935.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
-
46
-
-
1842864234
-
Plasma adiponectin levels and risk of myocardial infarction in men
-
Pischon T, Girman CJ, Hotamisligil GS, et al. Plasma adiponectin levels and risk of myocardial infarction in men. JAMA 2004; 291:1730-1737.
-
(2004)
JAMA
, vol.291
, pp. 1730-1737
-
-
Pischon, T.1
Girman, C.J.2
Hotamisligil, G.S.3
-
47
-
-
0037233878
-
Serum ghrelin levels in obese patients: The relationship to serum leptin levels and soluble leptin receptor levels
-
Rosicka M, Krsek M, Matoulek M, et al. Serum ghrelin levels in obese patients: the relationship to serum leptin levels and soluble leptin receptor levels. Physiol Res 2003; 52:61-66.
-
(2003)
Physiol Res
, vol.52
, pp. 61-66
-
-
Rosicka, M.1
Krsek, M.2
Matoulek, M.3
-
48
-
-
0035909997
-
Plasma leptin and the risk of cardiovascular disease in the West of Scotland Coronary Prevention Study (WOSCOPS)
-
Wallace AM, McMahon AD, Packard CJ, et al. Plasma leptin and the risk of cardiovascular disease in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation 2001; 104:3052-3056.
-
(2001)
Circulation
, vol.104
, pp. 3052-3056
-
-
Wallace, A.M.1
McMahon, A.D.2
Packard, C.J.3
-
49
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature 2001; 409:307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
-
50
-
-
10744220840
-
Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus
-
Youn BS, Yu KY, Park HU, et al. Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J Clin Endocrinol Metab 2004; 89:150-156.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 150-156
-
-
Youn, B.S.1
Yu, K.Y.2
Park, H.U.3
-
51
-
-
2342445056
-
Resistin: An adipocyte-derived hormone. Has it a role in diabetes and obesity?
-
Rea R, Donnelly R. Resistin: an adipocyte-derived hormone. Has it a role in diabetes and obesity? Diabetes Obes Metab 2004; 6:163-170.
-
(2004)
Diabetes Obes Metab
, vol.6
, pp. 163-170
-
-
Rea, R.1
Donnelly, R.2
-
52
-
-
0038413844
-
Efficacy and safety of low-carbohydrate diets: A systematic review
-
Bravata DM, Sanders L, Huang J, et al. Efficacy and safety of low-carbohydrate diets: a systematic review. JAMA 2003; 289:1837-1850.
-
(2003)
JAMA
, vol.289
, pp. 1837-1850
-
-
Bravata, D.M.1
Sanders, L.2
Huang, J.3
-
53
-
-
0038751994
-
A low carbohydrate as compared with low fat diet in severe obesity
-
Samaha FF, Iqbal N, Seshadri P, et al. A low carbohydrate as compared with low fat diet in severe obesity. N Engl J Med 2003; 348:2074-2081.
-
(2003)
N Engl J Med
, vol.348
, pp. 2074-2081
-
-
Samaha, F.F.1
Iqbal, N.2
Seshadri, P.3
-
54
-
-
0037737900
-
A randomized trial of a low-carbohydrate diet for obesity
-
Foster GD, Wyatt HR, Hill JO, et al. A randomized trial of a low-carbohydrate diet for obesity. N Engl J Med 2003; 348:2057-2058.
-
(2003)
N Engl J Med
, vol.348
, pp. 2057-2058
-
-
Foster, G.D.1
Wyatt, H.R.2
Hill, J.O.3
-
55
-
-
0035799806
-
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance
-
Tuomilehto J, Lindström J, Eriksson JG, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001; 344:1343-1350.
-
(2001)
N Engl J Med
, vol.344
, pp. 1343-1350
-
-
Tuomilehto, J.1
Lindström, J.2
Eriksson, J.G.3
-
56
-
-
0037034257
-
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
-
Knowler WC, Barrett-Connor E, Fowler SE, et al. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002; 346:393-403.
-
(2002)
N Engl J Med
, vol.346
, pp. 393-403
-
-
Knowler, W.C.1
Barrett-Connor, E.2
Fowler, S.E.3
-
57
-
-
19244365650
-
Thiazolidinediones
-
Yki-Jarvinen H. Thiazolidinediones. N Engl J Med 2004; 351:1106-1118.
-
(2004)
N Engl J Med
, vol.351
, pp. 1106-1118
-
-
Yki-Jarvinen, H.1
-
58
-
-
0030977450
-
Peroxisome proliferatoractivated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids
-
Vidal-Puig AJ, Considine RV, Jimenez-Linan M, et al. Peroxisome proliferatoractivated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids. J Clin Invest 1997; 99:2416-2422.
-
(1997)
J Clin Invest
, vol.99
, pp. 2416-2422
-
-
Vidal-Puig, A.J.1
Considine, R.V.2
Jimenez-Linan, M.3
-
59
-
-
0034068059
-
Troglitazone-induced fulminant hepatic failure
-
Murphy EJ, Davern TJ, Shakil AO, et al., Acute Liver Failure Study Group. Troglitazone-induced fulminant hepatic failure. Dig Dis Sci 2000; 45:549-553.
-
(2000)
Dig Dis Sci
, vol.45
, pp. 549-553
-
-
Murphy, E.J.1
Davern, T.J.2
Shakil, A.O.3
-
60
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-86.
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
61
-
-
7444231513
-
Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes
-
Choi D, Kim SK, Choi SH, et al. Preventative effects of rosiglitazone on restenosis after coronary stent implantation in patients with type 2 diabetes. Diabetes Care 2004; 27:2654-2660.
-
(2004)
Diabetes Care
, vol.27
, pp. 2654-2660
-
-
Choi, D.1
Kim, S.K.2
Choi, S.H.3
-
62
-
-
26244453309
-
Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial in macroVascular Events): A randomized controlled trial
-
Dormandy JA, Charbonnel B, Eckland DJA. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomized controlled trial. Lancet 2005; 366:1279-1289. Over 5000 patients with extensive macrovascular disease were randomized to pioglitazone or placebo. A small relative risk reduction in the secondary composite endpoint was found in patients treated with pioglitazone but perhaps due to improvement in lipid profile, A1c and blood pressure.
-
(2005)
Lancet
, vol.366
, pp. 1279-1289
-
-
Dormandy, J.A.1
Charbonnel, B.2
Eckland, D.J.A.3
-
63
-
-
21544466158
-
A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia
-
Goldberg RB, Kendall DM, Deeg MA, et al. A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with type 2 diabetes and dyslipidemia. Diabetes Care 2005; 28:1547-1554.
-
(2005)
Diabetes Care
, vol.28
, pp. 1547-1554
-
-
Goldberg, R.B.1
Kendall, D.M.2
Deeg, M.A.3
-
64
-
-
15944367788
-
Meta-analysis: Pharmacologic treatment of obesity
-
Li Z, Maglione M, Tu W, et al. Meta-analysis: pharmacologic treatment of obesity. Ann Intern Med 2005; 142:532-546.
-
(2005)
Ann Intern Med
, vol.142
, pp. 532-546
-
-
Li, Z.1
Maglione, M.2
Tu, W.3
-
65
-
-
27844487932
-
Randomized trial of lifestyle modification and pharmacotherapy for obesity
-
Wadden TA, Berkowitz RI, Womble LG, et al. Randomized trial of lifestyle modification and pharmacotherapy for obesity. N Engl J Med 2005; 353:2111-2120. A 1-year trial of obese adults (BMI 38 kg/m2) comparing sibutramine and lifestyle modification. The combination of medication and lifestyle modification resulted in the greatest weight loss.
-
(2005)
N Engl J Med
, vol.353
, pp. 2111-2120
-
-
Wadden, T.A.1
Berkowitz, R.I.2
Womble, L.G.3
-
66
-
-
1042303480
-
Xenical in the prevention of diabetes in obese subjects (XENDOS) study
-
Torgerson JS, Hauptman J, Boldrin MN. Xenical in the prevention of diabetes in obese subjects (XENDOS) study. Diabetes Care 2004; 27:155-161.
-
(2004)
Diabetes Care
, vol.27
, pp. 155-161
-
-
Torgerson, J.S.1
Hauptman, J.2
Boldrin, M.N.3
-
68
-
-
17144382751
-
Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study
-
Van Gaal LF, Rissanen AM, Scheen AJ, for the RIO-Europe Study Group. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study. Lancet 2005; 365:1389-1397. A 1-year trial demonstrated that rimonabant compared with placebo resulted in significantly greater weight loss, reduction in waist circumference, lipid profile, insulin resistance and prevalence of the metabolic syndrome.
-
(2005)
Lancet
, vol.365
, pp. 1389-1397
-
-
Van Gaal, L.F.1
Rissanen, A.M.2
Scheen, A.J.3
-
69
-
-
24644500204
-
The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through regulation of lipolysis and energy balance
-
Jbilo O, Ravinet-Trillou C, Arnone M, et al. The CB1 receptor antagonist rimonabant reverses the diet-induced obesity phenotype through regulation of lipolysis and energy balance. FASEB J 2005; 19:1567-1569.
-
(2005)
FASEB J
, vol.19
, pp. 1567-1569
-
-
Jbilo, O.1
Ravinet-Trillou, C.2
Arnone, M.3
-
70
-
-
27844463517
-
Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia
-
Despres JP, Golay A, Sjostrom L, for the Rimonabant in Obesity-Lipids Study Group. Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia. N Engl J Med 2005; 353:2121-2134. Over 1000 overweight and obese patients with dyslipidemia were randomized to either rimonabant or placebo. At 1 year patients treated with rimonabant had significantly greater weight loss, reduction in waist circumference, lipid profile and increase in adiponectin levels.
-
(2005)
N Engl J Med
, vol.353
, pp. 2121-2134
-
-
Despres, J.P.1
Golay, A.2
Sjostrom, L.3
-
71
-
-
17144414431
-
Fighting obesity and associated risk factors by antagonizing cannabinoid type 1 receptors
-
Pagotto U, Pasquali R. Fighting obesity and associated risk factors by antagonizing cannabinoid type 1 receptors. Lancet 2005; 365:1363-1364.
-
(2005)
Lancet
, vol.365
, pp. 1363-1364
-
-
Pagotto, U.1
Pasquali, R.2
-
72
-
-
32644441249
-
Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients
-
Pi-Sunyer FX, Aronne LJ, Heshmati HM, et al. Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients. JAMA 2005; 295:761-775. The RIO trial (RIO-North America) confirmed the efficacy of rimonabant but also evaluated the long-term effectiveness. After 1 year, rimonabant treated patients were re-randomized to receive placebo or continue on the same rimonabant dose. Patients who were switched from the rimonabant group to placebo regained the weight lost but patients who continued on rimonabant maintained their weight loss.
-
(2005)
JAMA
, vol.295
, pp. 761-775
-
-
Pi-Sunyer, F.X.1
Aronne, L.J.2
Heshmati, H.M.3
|