Novel drug discovery and molecular biological methods, via DNA, RNA and protein changes using structure-function transitions: Transitional structural chemogenomics, transitional structural chemoproteomics and novel multi-stranded nucleic acid microarray

Medical Hypotheses

Volumn 67, Issue 5, 2006, Pages 1099-1114

  Gagna, Claude E ^a,b   Lambert, W Clark ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b NEW YORK INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CHROMOSOME PROTEIN; CISPLATIN; COMPLEMENTARY DNA; DACTINOMYCIN; DNA BINDING PROTEIN; DNA Z; DOUBLE STRANDED DNA; PLATINUM DERIVATIVE; RNA; RNA BINDING PROTEIN; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; WP 900; ZETA CRYSTALLIN;

ARTICLE; CYTOTOXICITY; DNA CONFORMATION; DNA MICROARRAY; DNA STRUCTURE; DRUG RESEARCH; DRUG TARGETING; GENE CONTROL; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; GENE MUTATION; GENE TARGETING; GENOMICS; HUMAN; MOLECULAR BIOLOGY; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; PROTEOMICS; RNA EDITING; RNA INTERFERENCE; RNA SEQUENCE; RNA STRUCTURE; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; TRANSCRIPTION REGULATION; ULTRASTRUCTURE;

BASE SEQUENCE; COMPUTER SIMULATION; DNA; GENE EXPRESSION; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; MODELS, MOLECULAR; NUCLEIC ACID CONFORMATION; PLASMIDS; PROTEIN CONFORMATION; PROTEINS; PROTEOMICS; RNA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33748090286     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.05.020     Document Type: Article

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