-
1
-
-
0015914854
-
High association of an HL-A antigen, W27, with ankylosing spondylitis
-
Schlosstein L, Terasaki PI, Bluestone R, Pearson CM. High association of an HL-A antigen, W27, with ankylosing spondylitis. N Engl J Med 1973; 288:704-706.
-
(1973)
N Engl J Med
, vol.288
, pp. 704-706
-
-
Schlosstein, L.1
Terasaki, P.I.2
Bluestone, R.3
Pearson, C.M.4
-
3
-
-
0035075791
-
Whole-genome screening in ankylosing spondylitis: Evidence of non-MHC genetic-susceptibility loci
-
Laval SH, Timms A, Edwards S, et al. Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci. Am J Hum Genet 2001; 68:918-926.
-
(2001)
Am J Hum Genet
, vol.68
, pp. 918-926
-
-
Laval, S.H.1
Timms, A.2
Edwards, S.3
-
4
-
-
0031946030
-
A genome-wide screen for susceptibility loci in ankylosing spondylitis
-
Brown MA, Pile KD, Kennedy LG, et al. A genome-wide screen for susceptibility loci in ankylosing spondylitis. Arthritis Rheum 1998; 41:588-595.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 588-595
-
-
Brown, M.A.1
Pile, K.D.2
Kennedy, L.G.3
-
5
-
-
3142694774
-
Genetic studies in familial ankylosing spondylitis susceptibility
-
Zhang G, Luo J, Bruckel J, et al. Genetic studies in familial ankylosing spondylitis susceptibility. Arthritis Rheum 2004; 50:2246-2254.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 2246-2254
-
-
Zhang, G.1
Luo, J.2
Bruckel, J.3
-
6
-
-
4344652261
-
Significant linkage to spondyloarthropathy on 9q31-34
-
Miceli-Richard C, Zouali H, Said-Nahal R, et al. Significant linkage to spondyloarthropathy on 9q31-34. Hum Mol Genet 2004; 13:1641-1648.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1641-1648
-
-
Miceli-Richard, C.1
Zouali, H.2
Said-Nahal, R.3
-
7
-
-
84882539329
-
Pathogenesis of ankylosing spondylitis
-
Weisman MH, Reveille JD, van der Heijde D, editors. Philadelphia: Mosby
-
Reveille JD, Brown MA. Pathogenesis of ankylosing spondylitis. In: Weisman MH, Reveille JD, van der Heijde D, editors. Ankylosing spondylitis and the spondyloarthropathies. Philadelphia: Mosby; 2006. p. 28.
-
(2006)
Ankylosing Spondylitis and the Spondyloarthropathies
, pp. 28
-
-
Reveille, J.D.1
Brown, M.A.2
-
8
-
-
0037850989
-
Allospecific T cell epitope sharing reveals extensive conservation of the antigenic features of peptide ligands among HLA-B27 subtypes differentially associated with spondyloarthritis
-
Montserrat V, Marti M, Lopez de Castro JA. Allospecific T cell epitope sharing reveals extensive conservation of the antigenic features of peptide ligands among HLA-B27 subtypes differentially associated with spondyloarthritis. J Immunol 2003; 170:5778-5785.
-
(2003)
J Immunol
, vol.170
, pp. 5778-5785
-
-
Montserrat, V.1
Marti, M.2
Lopez De Castro, J.A.3
-
9
-
-
31044444245
-
Spondyloarthritis-associated and non spondyloarthritis-associated B27 subtypes differ in their dependence on tapasin for surface expression and their incorporation into the peptide loading complex
-
Goodall JC, Ellis L, Hill-Gaston JS. Spondyloarthritis-associated and non spondyloarthritis-associated B27 subtypes differ in their dependence on tapasin for surface expression and their incorporation into the peptide loading complex. Arthritis Rheum 2006; 54:139-147. An interesting analysis of the behavior of B*2704 and B*2705 in comparison with B*2706 and B*2709 during the loading of endogenous peptide onto the complex of HLA class I heavy chain that suggests that the ability to exhibit optimal cell surface expression in the absence of tapasin is not a prerequisite for susceptibility to AS.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 139-147
-
-
Goodall, J.C.1
Ellis, L.2
Hill-Gaston, J.S.3
-
10
-
-
0035887754
-
Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases
-
Kuon W, Holzhutter HG, Appel H, et al. Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases. J Immunol 2001; 167:4738-4746.
-
(2001)
J Immunol
, vol.167
, pp. 4738-4746
-
-
Kuon, W.1
Holzhutter, H.G.2
Appel, H.3
-
11
-
-
10644291011
-
The cell biology of the human natural killer cell CD94/NKG2A inhibitory receptor
-
Borrego F, Masilamani M, Kabat J, et al. The cell biology of the human natural killer cell CD94/NKG2A inhibitory receptor. Mol Immunol 2005; 42:485-488.
-
(2005)
Mol Immunol
, vol.42
, pp. 485-488
-
-
Borrego, F.1
Masilamani, M.2
Kabat, J.3
-
12
-
-
0037189545
-
HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum
-
Dangoria NS, DeLay ML, Kingsbury DJ, et al. HLA-B27 misfolding is associated with aberrant intermolecular disulfide bond formation (dimerization) in the endoplasmic reticulum. J Biol Chem 2002; 277:23459-23468.
-
(2002)
J Biol Chem
, vol.277
, pp. 23459-23468
-
-
Dangoria, N.S.1
DeLay, M.L.2
Kingsbury, D.J.3
-
13
-
-
0037352755
-
Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling
-
Bird LA, Peh CA, Kollnberger S, et al. Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling. Eur J Immunol 2003; 33:748-759.
-
(2003)
Eur J Immunol
, vol.33
, pp. 748-759
-
-
Bird, L.A.1
Peh, C.A.2
Kollnberger, S.3
-
14
-
-
0036846149
-
Cell-surface expression and immune receptor recognition of HLA-B27 homodimers
-
Kollnberger S, Bird L, Sun MY, et al. Cell-surface expression and immune receptor recognition of HLA-B27 homodimers. Arthritis Rheum 2002; 46:2972-2982.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2972-2982
-
-
Kollnberger, S.1
Bird, L.2
Sun, M.Y.3
-
15
-
-
0036179637
-
HLA-B27-transfected (Salmonella permissive) and HLA-A2-transfected (Salmonella nonpermissive) human monocytic U937 cells differ in their production of cytokines
-
Ekman P, Saarinen M, He Q, et al. HLA-B27-transfected (Salmonella permissive) and HLA-A2-transfected (Salmonella nonpermissive) human monocytic U937 cells differ in their production of cytokines. Infect Immun 2002; 70:1609-1614.
-
(2002)
Infect Immun
, vol.70
, pp. 1609-1614
-
-
Ekman, P.1
Saarinen, M.2
He, Q.3
-
16
-
-
0038318800
-
Determinants of synoviocyte clearance of arthritogenic bacteria
-
Inman RD, Payne U. Determinants of synoviocyte clearance of arthritogenic bacteria. J Rheumatol 2003; 30:1291-1297.
-
(2003)
J Rheumatol
, vol.30
, pp. 1291-1297
-
-
Inman, R.D.1
Payne, U.2
-
17
-
-
0035451748
-
The recognition of HLA-B27 by human CD4(+) T lymphocytes
-
Boyle LH, Goodall JC, Opat SS, Gaston JS. The recognition of HLA-B27 by human CD4(+) T lymphocytes. J Immunol 2001; 167:2619-2624.
-
(2001)
J Immunol
, vol.167
, pp. 2619-2624
-
-
Boyle, L.H.1
Goodall, J.C.2
Opat, S.S.3
Gaston, J.S.4
-
18
-
-
0037352593
-
Breaking the rules: The unconventional recognition of HLA-B27 by CD4+ T lymphocytes as an insight into the pathogenesis of the spondyloarthropathies
-
Oxford
-
Boyle LH, Gaston JS. Breaking the rules: the unconventional recognition of HLA-B27 by CD4+ T lymphocytes as an insight into the pathogenesis of the spondyloarthropathies. Rheumatology (Oxford) 2003; 42:404-412.
-
(2003)
Rheumatology
, vol.42
, pp. 404-412
-
-
Boyle, L.H.1
Gaston, J.S.2
-
19
-
-
0021347628
-
The risk of developing ankylosing spondylitis in HLA-B27 positive individuals A comparison of relatives of spondylitis patients with the general population
-
van der Linden SM, Valkenburg HA, de Jongh BM, Cats A. The risk of developing ankylosing spondylitis in HLA-B27 positive individuals A comparison of relatives of spondylitis patients with the general population. Arthritis Rheum 1984; 27:241-249.
-
(1984)
Arthritis Rheum
, vol.27
, pp. 241-249
-
-
Van Der Linden, S.M.1
Valkenburg, H.A.2
De Jongh, B.M.3
Cats, A.4
-
20
-
-
0031972623
-
Prevalence of spondylarthropathies in HLA-B27 positive and negative blood donors
-
Braun J, Bollow M, Remlinger G, et al. Prevalence of spondylarthropathies in HLA-B27 positive and negative blood donors. Arthritis Rheum 1998; 41:58-67.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 58-67
-
-
Braun, J.1
Bollow, M.2
Remlinger, G.3
-
21
-
-
0030783099
-
Susceptibility to ankylosing spondylitis in twins: The role of genes, HLA, and the environment
-
Brown MA, Kennedy LG, MacGregor AJ, et al. Susceptibility to ankylosing spondylitis in twins: the role of genes, HLA, and the environment. Arthritis Rheum 1997; 40:1823-1828.
-
(1997)
Arthritis Rheum
, vol.40
, pp. 1823-1828
-
-
Brown, M.A.1
Kennedy, L.G.2
MacGregor, A.J.3
-
22
-
-
0033768546
-
Recurrence risk modeling of the genetic susceptibility to ankylosing spondylitis
-
Brown MA, Laval SH, Brophy S, Calin A. Recurrence risk modeling of the genetic susceptibility to ankylosing spondylitis. Ann Rheum Dis 2000; 59:883-886.
-
(2000)
Ann Rheum Dis
, vol.59
, pp. 883-886
-
-
Brown, M.A.1
Laval, S.H.2
Brophy, S.3
Calin, A.4
-
23
-
-
0033812575
-
Diversity of alleles encoding HLA-B40: Relative frequencies in united states populations and description of five novel alleles
-
Pimtanothai N, Rizzuto GA, Slack R, et al. Diversity of alleles encoding HLA-B40: relative frequencies in united states populations and description of five novel alleles. Hum Immunol 2000; 61:808-815.
-
(2000)
Hum Immunol
, vol.61
, pp. 808-815
-
-
Pimtanothai, N.1
Rizzuto, G.A.2
Slack, R.3
-
24
-
-
0024462320
-
HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA-B27+ patients
-
Robinson WP, van der Linden SM, Khan MA, et al. HLA-Bw60 increases susceptibility to ankylosing spondylitis in HLA-B27+ patients. Arthritis Rheum 1989; 32:1135-1141.
-
(1989)
Arthritis Rheum
, vol.32
, pp. 1135-1141
-
-
Robinson, W.P.1
Van Der Linden, S.M.2
Khan, M.A.3
-
25
-
-
0027938087
-
Investigating the genetic basis for ankylosing spondylitis. Linkage studies with the major histocompatibility complex region
-
Rubin LA, Amos CI, Wade JA, et al. Investigating the genetic basis for ankylosing spondylitis. Linkage studies with the major histocompatibility complex region. Arthritis Rheum 1994; 37:212-220.
-
(1994)
Arthritis Rheum
, vol.37
, pp. 212-220
-
-
Rubin, L.A.1
Amos, C.I.2
Wade, J.A.3
-
26
-
-
0029879899
-
HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom
-
Brown MA, Pile KD, Kennedy LG, et al. HLA class I associations of ankylosing spondylitis in the white population in the United Kingdom. Ann Rheum Dis 1996; 55:268-270.
-
(1996)
Ann Rheum Dis
, vol.55
, pp. 268-270
-
-
Brown, M.A.1
Pile, K.D.2
Kennedy, L.G.3
-
27
-
-
3242890497
-
HLA-B60 and B61 are strongly associated with ankylosing spondylitis in HLA-B27-negative Taiwan Chinese patients
-
Oxford
-
Wei JC, Tsai WC, Lin HS, et al. HLA-B60 and B61 are strongly associated with ankylosing spondylitis in HLA-B27-negative Taiwan Chinese patients. Rheumatology (Oxford) 2004; 43:839-842.
-
(2004)
Rheumatology
, vol.43
, pp. 839-842
-
-
Wei, J.C.1
Tsai, W.C.2
Lin, H.S.3
-
28
-
-
0028851885
-
Association of HLA-B39 with HLA-B27-negative ankylosing spondylitis and pauciarticular juvenile rheumatoid arthritis in Japanese patients. Evidence for a role of the peptide-anchoring B pocket
-
Yamaguchi A, Tsuchiya N, Mitsui H, et al. Association of HLA-B39 with HLA-B27-negative ankylosing spondylitis and pauciarticular juvenile rheumatoid arthritis in Japanese patients. Evidence for a role of the peptide-anchoring B pocket. Arthritis Rheum 1995; 38:1672-1677.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 1672-1677
-
-
Yamaguchi, A.1
Tsuchiya, N.2
Mitsui, H.3
-
29
-
-
0021198630
-
Increased frequency of HLA-Bw62 and Bw35 CREG antigens HLA-B27 negative ankylosing spondylitis
-
Wagener P, Zeidler H, Eckert G, Deicher H. Increased frequency of HLA-Bw62 and Bw35 CREG antigens HLA-B27 negative ankylosing spondylitis. Z Rheumatol 1984; 43:253-257.
-
(1984)
Z Rheumatol
, vol.43
, pp. 253-257
-
-
Wagener, P.1
Zeidler, H.2
Eckert, G.3
Deicher, H.4
-
30
-
-
0034927801
-
Microsatellite polymorphism of the MICA gene and susceptibility to rheumatoid arthritis
-
Singal DP, Li J, Zhang G. Microsatellite polymorphism of the MICA gene and susceptibility to rheumatoid arthritis. Clin Exp Rheumatol 2001; 19:451-452.
-
(2001)
Clin Exp Rheumatol
, vol.19
, pp. 451-452
-
-
Singal, D.P.1
Li, J.2
Zhang, G.3
-
31
-
-
0033822106
-
MICA gene triplet repeat polymorphism in patients with HLA-B27 positive and negative ankylosing spondylitis from Sardinia
-
Ricci-Vitiani L, Vacca A, Potolicchio I, et al. MICA gene triplet repeat polymorphism in patients with HLA-B27 positive and negative ankylosing spondylitis from Sardinia. J Rheumatol 2000; 27:2193-2197.
-
(2000)
J Rheumatol
, vol.27
, pp. 2193-2197
-
-
Ricci-Vitiani, L.1
Vacca, A.2
Potolicchio, I.3
-
32
-
-
0032954252
-
Triplet repeat polymorphism in the MICA gene in HLA-B27 positive and negative Caucasian patients with ankylosing spondylitis
-
Yabuki K, Ota M, Goto K, et al. Triplet repeat polymorphism in the MICA gene in HLA-B27 positive and negative Caucasian patients with ankylosing spondylitis. Hum Immunol 1999; 60:83-86.
-
(1999)
Hum Immunol
, vol.60
, pp. 83-86
-
-
Yabuki, K.1
Ota, M.2
Goto, K.3
-
33
-
-
0033984789
-
HLA-B27 alone rather than B27-related class I haplotypes contributes to ankylosing spondylitis susceptibility
-
Martinez-Borra J, Gonzalez S, Lopez-Vazquez A, et al. HLA-B27 alone rather than B27-related class I haplotypes contributes to ankylosing spondylitis susceptibility. Hum Immunol 2000; 61:131-139.
-
(2000)
Hum Immunol
, vol.61
, pp. 131-139
-
-
Martinez-Borra, J.1
Gonzalez, S.2
Lopez-Vazquez, A.3
-
34
-
-
0031933251
-
The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis
-
Brown MA, Kennedy LG, Darke C, et al. The effect of HLA-DR genes on susceptibility to and severity of ankylosing spondylitis. Arthritis Rheum 1998; 41:460-465.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 460-465
-
-
Brown, M.A.1
Kennedy, L.G.2
Darke, C.3
-
35
-
-
0036183453
-
The role of HLA genes in familial spondyloarthropathy: A comprehensive study of 70 multiplex families
-
Said-Nahal R, Miceli-Richard C, Gautreau C, et al. The role of HLA genes in familial spondyloarthropathy: a comprehensive study of 70 multiplex families. Ann Rheum Dis 2002; 61:201-206.
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 201-206
-
-
Said-Nahal, R.1
Miceli-Richard, C.2
Gautreau, C.3
-
36
-
-
0028915924
-
HLA-DR8 and acute anterior uveitis in ankylosing spondylitis
-
Monowarul-Islam SM, Numaga J, Fujino Y, et al. HLA-DR8 and acute anterior uveitis in ankylosing spondylitis. Arthritis Rheum 1995; 38:547-550.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 547-550
-
-
Monowarul-Islam, S.M.1
Numaga, J.2
Fujino, Y.3
-
37
-
-
0028863229
-
Association to HLA-DRB1*08, HLA-DPB1*0301 and homozygosity for an HLA-linked proteasome gene in juvenile ankylosing spondylitis
-
Ploski R, Flato B, Vinje O, et al. Association to HLA-DRB1*08, HLA-DPB1*0301 and homozygosity for an HLA-linked proteasome gene in juvenile ankylosing spondylitis. Hum Immunol 1995; 44:88-96.
-
(1995)
Hum Immunol
, vol.44
, pp. 88-96
-
-
Ploski, R.1
Flato, B.2
Vinje, O.3
-
38
-
-
0028947432
-
Susceptibility to Reiter's syndrome is associated with alleles of TAP genes
-
Barron KS, Reveille JD, Carrington M, et al. Susceptibility to Reiter's syndrome is associated with alleles of TAP genes. Arthritis Rheum 1995; 38:684-689.
-
(1995)
Arthritis Rheum
, vol.38
, pp. 684-689
-
-
Barron, K.S.1
Reveille, J.D.2
Carrington, M.3
-
39
-
-
0029956786
-
Specificities of human TAP alleles for HLA-B27 binding peptides
-
Kuipers JG, Raybourne RB, Williams KM, et al. Specificities of human TAP alleles for HLA-B27 binding peptides. Arthritis Rheum 1996; 39:1892-1895.
-
(1996)
Arthritis Rheum
, vol.39
, pp. 1892-1895
-
-
Kuipers, J.G.1
Raybourne, R.B.2
Williams, K.M.3
-
40
-
-
0033661963
-
TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis
-
Fraile A, Collado MD, Mataran L, et al. TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis. Exp Clin Immunogenet 2000; 17:199-204.
-
(2000)
Exp Clin Immunogenet
, vol.17
, pp. 199-204
-
-
Fraile, A.1
Collado, M.D.2
Mataran, L.3
-
41
-
-
9744262548
-
Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery
-
Paulsson KM. Evolutionary and functional perspectives of the major histocompatibility complex class I antigen-processing machinery. Cell Mol Life Sci 2004; 61:2446-2460.
-
(2004)
Cell Mol Life Sci
, vol.61
, pp. 2446-2460
-
-
Paulsson, K.M.1
-
42
-
-
10444287598
-
Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis
-
Vargas-Alarcon G, Gamboa R, Zuniga J, et al. Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis. Hum Immunol 2004; 65:1437-1442.
-
(2004)
Hum Immunol
, vol.65
, pp. 1437-1442
-
-
Vargas-Alarcon, G.1
Gamboa, R.2
Zuniga, J.3
-
43
-
-
0030850379
-
Polymorphism of the LMP2 gene and disease phenotype in ankylosing spondylitis: No association with disease severity
-
Maksymowych WP, Adlam N, Lind D, Russell AS. Polymorphism of the LMP2 gene and disease phenotype in ankylosing spondylitis: no association with disease severity. Clin Rheumatol 1997; 16:461-465.
-
(1997)
Clin Rheumatol
, vol.16
, pp. 461-465
-
-
Maksymowych, W.P.1
Adlam, N.2
Lind, D.3
Russell, A.S.4
-
44
-
-
0031908966
-
Association of large molecular weight proteasome 7 gene polymorphism with ankylosing spondylitis
-
Fraile A, Nieto A, Vinasco J, et al. Association of large molecular weight proteasome 7 gene polymorphism with ankylosing spondylitis. Arthritis Rheum 1998; 41:560-562.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 560-562
-
-
Fraile, A.1
Nieto, A.2
Vinasco, J.3
-
45
-
-
0035170976
-
Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: Its relation to HLA-B27 and influence of the TNF-308 gene polymorphism
-
Rudwaleit M, Siegert S, Yin Z, et al. Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism. Ann Rheum Dis 2001; 60:36-42.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 36-42
-
-
Rudwaleit, M.1
Siegert, S.2
Yin, Z.3
-
46
-
-
0032913388
-
The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27
-
McGarry F, Walker R, Sturrock R, Field M. The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27. J Rheumatol 1999; 26:1110-1116.
-
(1999)
J Rheumatol
, vol.26
, pp. 1110-1116
-
-
McGarry, F.1
Walker, R.2
Sturrock, R.3
Field, M.4
-
47
-
-
0034303168
-
Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis
-
Milicic A, Lindheimer F, Laval S, et al. Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. Genes Immun 2000; 1:418-422.
-
(2000)
Genes Immun
, vol.1
, pp. 418-422
-
-
Milicic, A.1
Lindheimer, F.2
Laval, S.3
-
48
-
-
0031855604
-
Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals
-
Hohler T, Schaper T, Schneider PM, et al. Association of different tumor necrosis factor alpha promoter allele frequencies with ankylosing spondylitis in HLA-B27 positive individuals. Arthritis Rheum 1998; 41:1489-1492.
-
(1998)
Arthritis Rheum
, vol.41
, pp. 1489-1492
-
-
Hohler, T.1
Schaper, T.2
Schneider, P.M.3
-
49
-
-
0028048678
-
Polymorphism of tumour necrosis factor-alpha (TNF-alpha) at position -308 in relation to ankylosing spondylitis
-
Verjans GM, Brinkman BM, Van Doornik CE, et al. Polymorphism of tumour necrosis factor-alpha (TNF-alpha) at position -308 in relation to ankylosing spondylitis. Clin Exp Immunol 1994; 97:45-47.
-
(1994)
Clin Exp Immunol
, vol.97
, pp. 45-47
-
-
Verjans, G.M.1
Brinkman, B.M.2
Van Doornik, C.E.3
-
50
-
-
0034982051
-
TNF-238A promoter polymorphism contributes to susceptibility to ankylosing spondylitis in HLA-B27 negative patients
-
Gonzalez S, Torre-Alonso JC, Martinez-Borra J, et al. TNF-238A promoter polymorphism contributes to susceptibility to ankylosing spondylitis in HLA-B27 negative patients. J Rheumatol 2001; 28:1288-1293.
-
(2001)
J Rheumatol
, vol.28
, pp. 1288-1293
-
-
Gonzalez, S.1
Torre-Alonso, J.C.2
Martinez-Borra, J.3
-
51
-
-
0036145057
-
Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies
-
Vargas-Alarcon G, Londono JD, Hernandez-Pacheco G, et al. Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies. Ann Rheum Dis 2002; 61:48-51.
-
(2002)
Ann Rheum Dis
, vol.61
, pp. 48-51
-
-
Vargas-Alarcon, G.1
Londono, J.D.2
Hernandez-Pacheco, G.3
-
52
-
-
33748054527
-
Meta-analysis of three whole genome linkage scans for ankylosing spondylitis
-
Carter KW, Pluzhnikov A, Timms AE, et al. Meta-analysis of three whole genome linkage scans for ankylosing spondylitis. Arthritis Rheum 2005; 52(Suppl):S241.
-
(2005)
Arthritis Rheum
, vol.52
, Issue.SUPPL.
-
-
Carter, K.W.1
Pluzhnikov, A.2
Timms, A.E.3
-
53
-
-
0034974632
-
Is disease severity in ankylosing spondylitis genetically determined?
-
Hamersma J, Cardon LR, Bradbury L, et al. Is disease severity in ankylosing spondylitis genetically determined? Arthritis Rheum 2001; 44:1396-1400.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1396-1400
-
-
Hamersma, J.1
Cardon, L.R.2
Bradbury, L.3
-
54
-
-
0042072981
-
Identification of major loci controlling clinical manifestations of ankylosing spondylitis
-
Brown MA, Brophy S, Bradbury L, et al. Identification of major loci controlling clinical manifestations of ankylosing spondylitis. Arthritis Rheum 2003; 48:2234-2239.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2234-2239
-
-
Brown, M.A.1
Brophy, S.2
Bradbury, L.3
-
55
-
-
26444478566
-
Interleukin 1 and nuclear factor-kappaB polymorphisms in ankylosing spondylitis in Canada and Korea
-
Kim TH, Stone MA, Rahman P, et al. Interleukin 1 and nuclear factor-kappaB polymorphisms in ankylosing spondylitis in Canada and Korea. J Rheumatol 2005; 32:1907-1910. No differences of IL-1α, IL-1β, IL-1Ra, and NF-κB polymorphisms between AS patients and controls were seen in these populations, although at least in the Toronto cohort the small number of patients examined do not rule out a false negative due to power concerns.
-
(2005)
J Rheumatol
, vol.32
, pp. 1907-1910
-
-
Kim, T.H.1
Stone, M.A.2
Rahman, P.3
-
56
-
-
33644893323
-
Association of the IL1 gene cluster with susceptibility to ankylosing spondylitis: An analysis of three Canadian populations
-
Maksymowych WP, Rahman P, Reeve JP, et al. Association of the IL1 gene cluster with susceptibility to ankylosing spondylitis: an analysis of three Canadian populations. Arthritis Rheum 2006; 54:974-985.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 974-985
-
-
Maksymowych, W.P.1
Rahman, P.2
Reeve, J.P.3
-
57
-
-
0035924918
-
Interleukin 1 gene cluster polymorphisms in multiplex families with spondylarthropathies
-
Djouadi K, Nedelec B, Tamouza R, et al. Interleukin 1 gene cluster polymorphisms in multiplex families with spondylarthropathies. Cytokine 2001; 13:98-103.
-
(2001)
Cytokine
, vol.13
, pp. 98-103
-
-
Djouadi, K.1
Nedelec, B.2
Tamouza, R.3
-
58
-
-
4444360926
-
Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility
-
Jin L, Zhang G, Akey JM, et al. Lack of linkage of IL1RN genotypes with ankylosing spondylitis susceptibility. Arthritis Rheum 2004; 50:3047-3048.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3047-3048
-
-
Jin, L.1
Zhang, G.2
Akey, J.M.3
-
59
-
-
4544361392
-
The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis
-
Timms AE, Crane AM, Sims AM, et al. The interleukin 1 gene cluster contains a major susceptibility locus for ankylosing spondylitis. Am J Hum Genet 2004; 75:587-595.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 587-595
-
-
Timms, A.E.1
Crane, A.M.2
Sims, A.M.3
-
60
-
-
33748048552
-
Replication of association of IL-1 gene complex members with ankylosing spondylitis in Taiwanese Chinese
-
Dec 16; [Epub ahead of print]
-
Chou C-T, Timms AE, Wei JC, et al. Replication of association of IL-1 gene complex members with ankylosing spondylitis in Taiwanese Chinese. Ann Rheum Dis 2005 Dec 16; [Epub ahead of print]. This group finds association of AS with all the five IL-1 region SNPs studied (IL-1F10.3, IL-1RN.4 and IL-1RN.VNTR), though IL-1A was not studied here.
-
(2005)
Ann Rheum Dis
-
-
Chou, C.-T.1
Timms, A.E.2
Wei, J.C.3
-
61
-
-
0038342695
-
High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry
-
Maksymowych WP, Reeve JP, Reveille JD, et al. High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-assisted laser desorption ionization-time-of- flight mass spectrometry. Arthritis Rheum 2003; 48:2011-2018.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2011-2018
-
-
Maksymowych, W.P.1
Reeve, J.P.2
Reveille, J.D.3
-
62
-
-
33744911534
-
Fine-mapping of the IL-1 gene cluster pinpoints genetic associations with ankylosing spondylitis
-
Sims AM, Timms A, Pointon JJ, et al. Fine-mapping of the IL-1 gene cluster pinpoints genetic associations with ankylosing spondylitis. Arthritis Rheum 2005; 59:S576.
-
(2005)
Arthritis Rheum
, vol.59
-
-
Sims, A.M.1
Timms, A.2
Pointon, J.J.3
-
63
-
-
33744910978
-
Association of IL-1 genes with ankylosing spondylitis susceptibility. Evidence from family-based analyses
-
Albuquerque S, Zhang G, Zhou X, et al. Association of IL-1 genes with ankylosing spondylitis susceptibility. Evidence from family-based analyses. Arthritis Rheum 2005; 52:F35/529.
-
(2005)
Arthritis Rheum
, vol.52
-
-
Albuquerque, S.1
Zhang, G.2
Zhou, X.3
-
64
-
-
0347724078
-
Interleukin 1alpha, interleukin 1beta and interleukin 1 receptor gene polymorphisms in psoriatic arthritis
-
Oxford
-
Ravindran JS, Owen P, Lagan A, et al. Interleukin 1alpha, interleukin 1beta and interleukin 1 receptor gene polymorphisms in psoriatic arthritis. Rheumatology (Oxford) 2004; 43:22-26.
-
(2004)
Rheumatology
, vol.43
, pp. 22-26
-
-
Ravindran, J.S.1
Owen, P.2
Lagan, A.3
-
65
-
-
0030030519
-
Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis
-
Beyeler C, Armstrong M, Bird HA, et al. Relationship between genotype for the cytochrome P450 CYP2D6 and susceptibility to ankylosing spondylitis and rheumatoid arthritis. Ann Rheum Dis 1996; 55:66-68.
-
(1996)
Ann Rheum Dis
, vol.55
, pp. 66-68
-
-
Beyeler, C.1
Armstrong, M.2
Bird, H.A.3
-
66
-
-
0034235730
-
Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis
-
Brown MA, Edwards S, Hoyle E, et al. Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis. Hum Mol Genet 2000; 9:1563-1566.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1563-1566
-
-
Brown, M.A.1
Edwards, S.2
Hoyle, E.3
-
67
-
-
0023718182
-
Spondyloarthropathy in progressive ankylosis (ank/ank) mice: Morphological features
-
Sampson HW. Spondyloarthropathy in progressive ankylosis (ank/ank) mice: morphological features. Spine 1988; 13:645-649.
-
(1988)
Spine
, vol.13
, pp. 645-649
-
-
Sampson, H.W.1
-
68
-
-
0031034913
-
Murine progressive ankylosis is not immunologically mediated
-
Krug HE, Wietgrefe MM, Ytterberg SR, et al. Murine progressive ankylosis is not immunologically mediated. J Rheumatol 1997; 24:115-122.
-
(1997)
J Rheumatol
, vol.24
, pp. 115-122
-
-
Krug, H.E.1
Wietgrefe, M.M.2
Ytterberg, S.R.3
-
69
-
-
0034020871
-
HLA-B27 has no effect on the phenotypic expression of progressive ankylosis in ank/ank mice
-
Krug HE, Taurog JD. HLA-B27 has no effect on the phenotypic expression of progressive ankylosis in ank/ank mice. J Rheumatol 2000; 27:1257-1259.
-
(2000)
J Rheumatol
, vol.27
, pp. 1257-1259
-
-
Krug, H.E.1
Taurog, J.D.2
-
70
-
-
0037333553
-
Novel genetic markers in the 5′-flanking region of ANKH are associated with ankylosing spondylitis
-
Tsui FW, Tsui HW, Cheng EY, et al. Novel genetic markers in the 5′-flanking region of ANKH are associated with ankylosing spondylitis. Arthritis Rheum 2003; 48:791-797.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 791-797
-
-
Tsui, F.W.1
Tsui, H.W.2
Cheng, E.Y.3
-
71
-
-
33644624656
-
ANKH variants associated with ankylosing spondylitis: Gender differences
-
Tsui HW, Inman RD, Paterson AD, et al. ANKH variants associated with ankylosing spondylitis: Gender differences. Arthritis Res Ther 2005; 7:513-525. This group has extended their original observation, finding gender differences in the role of ANKH in susceptibility to AS. Given the lack of confirmation from the Oxford group of their previous study, clearly more work is needed in other groups.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 513-525
-
-
Tsui, H.W.1
Inman, R.D.2
Paterson, A.D.3
-
72
-
-
0142135638
-
Investigation of the role of ANKH in ankylosing spondylitis
-
Timms AE, Zhang Y, Bradbury L, et al. Investigation of the role of ANKH in ankylosing spondylitis. Arthritis Rheum 2003; 48:2898-2902.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2898-2902
-
-
Timms, A.E.1
Zhang, Y.2
Bradbury, L.3
-
73
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411:599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
-
74
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411:603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
-
75
-
-
0021737723
-
Macroscopic and histological changes of the ileum HLA-B27 related diseases: Therapeutic consequences
-
Mielants H, Veys EM, Cuvelier C, De VM. Macroscopic and histological changes of the ileum HLA-B27 related diseases: therapeutic consequences. Int J Clin Pharmacol Res 1984; 4:409-414.
-
(1984)
Int J Clin Pharmacol Res
, vol.4
, pp. 409-414
-
-
Mielants, H.1
Veys, E.M.2
Cuvelier, C.3
De, V.M.4
-
77
-
-
0029048114
-
Ankylosing spondylitis, IgA, and transforming growth factors
-
Archer JR. Ankylosing spondylitis, IgA, and transforming growth factors. Ann Rheum Dis 1995; 54:544-546.
-
(1995)
Ann Rheum Dis
, vol.54
, pp. 544-546
-
-
Archer, J.R.1
-
78
-
-
0347867155
-
A polymorphism within the transforming growth factor beta 1 gene is associated with ankylosing spondylitis (AS)
-
Oxford
-
McGarry F, Cousins L, Sturrock RD, Field M. A polymorphism within the transforming growth factor beta 1 gene is associated with ankylosing spondylitis (AS). Rheumatology (Oxford) 2001; 41 (Suppl 1):16.
-
(2001)
Rheumatology
, vol.41
, Issue.1 SUPPL.
, pp. 16
-
-
McGarry, F.1
Cousins, L.2
Sturrock, R.D.3
Field, M.4
-
79
-
-
9144250214
-
The effect of transforming growth factor β1 gene polymorphisms in ankylosing spondylitis
-
Oxford
-
Jaakkola E, Crane AM, Laiho K, et al. The effect of transforming growth factor β1 gene polymorphisms in ankylosing spondylitis. Rheumatology (Oxford) 2003; 43:32-38.
-
(2003)
Rheumatology
, vol.43
, pp. 32-38
-
-
Jaakkola, E.1
Crane, A.M.2
Laiho, K.3
-
80
-
-
16344365852
-
Susceptibility to ankylosing spondylitis: No evidence for the involvement of transforming growth factor beta 1 (TGFB1) gene polymorphisms
-
van der Paardt M, Crusius JB, Garcia-Gonzalez MA, et al. Susceptibility to ankylosing spondylitis: no evidence for the involvement of transforming growth factor beta 1 (TGFB1) gene polymorphisms. Ann Rheum Dis 2005; 64:616-619. A rather small negative study of TGFB1 SNPs in Dutch AS patients. On the basis of this study and others, little role for this locus in AS susceptibility is apparent.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 616-619
-
-
Van Der Paardt, M.1
Crusius, J.B.2
Garcia-Gonzalez, M.A.3
-
81
-
-
19944428359
-
Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis
-
Oxford
-
Howe HS, Cheung PL, Kong KO, et al. Transforming growth factor beta-1 and gene polymorphisms in oriental ankylosing spondylitis. Rheumatology (Oxford) 2005; 44:51-54.
-
(2005)
Rheumatology
, vol.44
, pp. 51-54
-
-
Howe, H.S.1
Cheung, P.L.2
Kong, K.O.3
-
82
-
-
19944426684
-
Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity
-
Oxford
-
Jin L, Weisman M, Zhang G, et al. Lack of association of matrix metalloproteinase 3 (MMP3) genotypes with ankylosing spondylitis susceptibility and severity. Rheumatology (Oxford) 2005; 44:55-60. A moderate-sized study of MMP3 SNPS in families and unrelated patients with AS. No association was seen of any of the MMP3 SNPs with functional impairment in AS.
-
(2005)
Rheumatology
, vol.44
, pp. 55-60
-
-
Jin, L.1
Weisman, M.2
Zhang, G.3
-
83
-
-
0034744285
-
IL10.G microsatellites mark promoter haplotypes associated with protection against the development of reactive arthritis in Finnish patients
-
Kaluza W, Leirisalo-Repo M, Marker-Hermann E, et al. IL10.G microsatellites mark promoter haplotypes associated with protection against the development of reactive arthritis in Finnish patients. Arthritis Rheum 2001; 44:1209-1214.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1209-1214
-
-
Kaluza, W.1
Leirisalo-Repo, M.2
Marker-Hermann, E.3
-
84
-
-
0037491044
-
Interleukin 10 polymorphisms in ankylosing spondylitis
-
Goedecke V, Crane AM, Jaakkola E, et al. Interleukin 10 polymorphisms in ankylosing spondylitis. Genes Immun 2003; 4:74-76.
-
(2003)
Genes Immun
, vol.4
, pp. 74-76
-
-
Goedecke, V.1
Crane, A.M.2
Jaakkola, E.3
-
85
-
-
0034123190
-
Interleukin 6 gene promoter polymorphism is not associated with ankylosing spondylitis
-
Collado-Escobar MD, Nieto A, Mataran L, et al. Interleukin 6 gene promoter polymorphism is not associated with ankylosing spondylitis. J Rheumatol 2000; 27:1461-1463.
-
(2000)
J Rheumatol
, vol.27
, pp. 1461-1463
-
-
Collado-Escobar, M.D.1
Nieto, A.2
Mataran, L.3
-
86
-
-
0023195410
-
Genes on chromosome 14q and their role in the pathogenesis of HLA-B27 associated diseases
-
Linssen A, Rothova A, Broekema N, et al. Genes on chromosome 14q and their role in the pathogenesis of HLA-B27 associated diseases. Clin Exp Rheumatol 1987; 5 (Suppl 1):S89-S95.
-
(1987)
Clin Exp Rheumatol
, vol.5
, Issue.1 SUPPL.
-
-
Linssen, A.1
Rothova, A.2
Broekema, N.3
-
87
-
-
0023050512
-
Association of Gm allotypes with the occurrence of ankylosing spondylitis in HLA-B27-positive anterior uveitis
-
Broekema N, Linssen A, Luyendijk L, et al. Association of Gm allotypes with the occurrence of ankylosing spondylitis in HLA-B27-positive anterior uveitis. Am J Ophthalmol 1986; 102:549.
-
(1986)
Am J Ophthalmol
, vol.102
, pp. 549
-
-
Broekema, N.1
Linssen, A.2
Luyendijk, L.3
-
88
-
-
0021688180
-
Association of Gm allotypes with the occurrence of ankylosing spondylitis in HLA-B27-positive anterior uveitis
-
Kijlstra A, Linssen A, Ockhuizen T. Association of Gm allotypes with the occurrence of ankylosing spondylitis in HLA-B27-positive anterior uveitis. Am J Ophthalmol 1984; 98:732-735.
-
(1984)
Am J Ophthalmol
, vol.98
, pp. 732-735
-
-
Kijlstra, A.1
Linssen, A.2
Ockhuizen, T.3
-
89
-
-
0021253370
-
HLA-B27 and allotypes of complement components in ankylosing spondylitis
-
Gran JT, Teisberg P, Olaissen B, et al. HLA-B27 and allotypes of complement components in ankylosing spondylitis. J Rheumatol 1984; 11:324-326.
-
(1984)
J Rheumatol
, vol.11
, pp. 324-326
-
-
Gran, J.T.1
Teisberg, P.2
Olaissen, B.3
-
90
-
-
0021218543
-
Immunoglobulin allotypes in psoriasis, psoriatic arthropathy and ankylosing spondylitis
-
Demaine AG, Panayi GS, Vaughan RW, et al. Immunoglobulin allotypes in psoriasis, psoriatic arthropathy and ankylosing spondylitis. Exp Clin Immunogenet 1984; 1:61-65.
-
(1984)
Exp Clin Immunogenet
, vol.1
, pp. 61-65
-
-
Demaine, A.G.1
Panayi, G.S.2
Vaughan, R.W.3
-
91
-
-
0023770127
-
Immunoglobulin allotype Gm(1,2;21) in ankylosing spondylitis with peripheral arthritis
-
Mierau R, von Muhlen CA, Zarnowski H, et al. Immunoglobulin allotype Gm(1,2;21) in ankylosing spondylitis with peripheral arthritis. Ann Rheum Dis 1988; 47:893-897.
-
(1988)
Ann Rheum Dis
, vol.47
, pp. 893-897
-
-
Mierau, R.1
Von Muhlen, C.A.2
Zarnowski, H.3
-
92
-
-
0031875219
-
The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis
-
Brown MA, Rudwaleit M, Pile KD, et al. The role of germline polymorphisms in the T-cell receptor in susceptibility to ankylosing spondylitis. Br J Rheumatol 1998; 37:454-458.
-
(1998)
Br J Rheumatol
, vol.37
, pp. 454-458
-
-
Brown, M.A.1
Rudwaleit, M.2
Pile, K.D.3
-
93
-
-
0034121873
-
Polymorphic CAG repeats of the androgen receptor gene in Japanese male patients with ankylosing spondylitis
-
Oxford
-
Mori K, Ushiyama T, Inoue K, Hukuda S. Polymorphic CAG repeats of the androgen receptor gene in Japanese male patients with ankylosing spondylitis. Rheumatology (Oxford) 2000; 39:530-532.
-
(2000)
Rheumatology
, vol.39
, pp. 530-532
-
-
Mori, K.1
Ushiyama, T.2
Inoue, K.3
Hukuda, S.4
-
94
-
-
13244292652
-
No evidence for involvement of the Toll-like receptor 4 (TLR4) A896G and CD14-C260T polymorphisms in susceptibility to ankylosing spondylitis
-
van der Paardt M, Crusius JB, de Koning MH, et al. No evidence for involvement of the Toll-like receptor 4 (TLR4) A896G and CD14-C260T polymorphisms in susceptibility to ankylosing spondylitis. Ann Rheum Dis 2005; 64:235-238. A negative study of CD14 C-260T and TLR4 A896G polymorphisms in Dutch ankylosing spondylitis patients. However, due to the rather small sample size and the growing importance of toll-like receptor polymorphisms in other diseases, it would be premature to exclude this locus in ankylosing spondylitis susceptibly at this time based on these data.
-
(2005)
Ann Rheum Dis
, vol.64
, pp. 235-238
-
-
Van Der Paardt, M.1
Crusius, J.B.2
De Koning, M.H.3
-
96
-
-
0037227353
-
Lack of association of ankylosing spondylitis with the most common NOD2 susceptibility alleles to Crohn's disease
-
Ferreiros-Vidal I, Amarelo J, Barros F, et al. Lack of association of ankylosing spondylitis with the most common NOD2 susceptibility alleles to Crohn's disease. J Rheumatol 2003; 30:102-104.
-
(2003)
J Rheumatol
, vol.30
, pp. 102-104
-
-
Ferreiros-Vidal, I.1
Amarelo, J.2
Barros, F.3
-
97
-
-
0036842120
-
The Crohn's associated NOD2 3020InsC frameshift mutation does not confer susceptibility to ankylosing spondylitis
-
D'Amato M. The Crohn's associated NOD2 3020InsC frameshift mutation does not confer susceptibility to ankylosing spondylitis. J Rheumatol 2002; 29:2470-2471.
-
(2002)
J Rheumatol
, vol.29
, pp. 2470-2471
-
-
D'Amato, M.1
-
98
-
-
5044225189
-
Analysis of CARD15 polymorphisms in Korean patients with ankylosing spondylitis reveals absence of common variants seen in western populations
-
Kim TH, Rahman P, Jun JB, et al. Analysis of CARD15 polymorphisms in Korean patients with ankylosing spondylitis reveals absence of common variants seen in western populations. J Rheumatol 2004; 31:1959-1961.
-
(2004)
J Rheumatol
, vol.31
, pp. 1959-1961
-
-
Kim, T.H.1
Rahman, P.2
Jun, J.B.3
-
99
-
-
33646231253
-
Lack of association between ankylosing spondylitis and a functional polymorphism of PTPN22 proposed as a general susceptibility marker for autoimmunity
-
Orozco G, Garcia-Porrua C, Lopez-Nevot MA, et al. Lack of association between ankylosing spondylitis and a functional polymorphism of PTPN22 proposed as a general susceptibility marker for autoimmunity. Ann Rheum Dis 2006; 65:687-688. Apparently the PTPN22 association with other systemic autoimmune disease does not carry over to AS, at least in this small-to-moderately sized cohort.
-
(2006)
Ann Rheum Dis
, vol.65
, pp. 687-688
-
-
Orozco, G.1
Garcia-Porrua, C.2
Lopez-Nevot, M.A.3
-
100
-
-
27144462599
-
Influence of VEGF gene polymorphisms on the severity of ankylosing spondylitis
-
Oxford
-
Seo JS, Lee SS, Kim SI, et al. Influence of VEGF gene polymorphisms on the severity of ankylosing spondylitis. Rheumatology (Oxford) 2005; 44:1299-1302. A moderate sized study of VEGF SNPs in Korean AS patients - essentially a negative study, except for a possible association with cervical spine involvement.
-
(2005)
Rheumatology
, vol.44
, pp. 1299-1302
-
-
Seo, J.S.1
Lee, S.S.2
Kim, S.I.3
-
101
-
-
0035754610
-
Alpha-1-antitrypsin phenotypes in patients with ankylosing spondylitis
-
Sierakowski S, Chwiecko J, Kita K. Alpha-1-antitrypsin phenotypes in patients with ankylosing spondylitis. Rocz Akad Med Bialymst 2001; 46:54-59.
-
(2001)
Rocz Akad Med Bialymst
, vol.46
, pp. 54-59
-
-
Sierakowski, S.1
Chwiecko, J.2
Kita, K.3
-
102
-
-
0017782526
-
Less of MH alpha 1-antitrypsin phenotypes in rheumatoid arthritis and ankylosing spondylitis
-
Buisseret PD, Pembrey ME. Less of MH alpha 1-antitrypsin phenotypes in rheumatoid arthritis and ankylosing spondylitis. Lancet 1977; 2:1358-1359.
-
(1977)
Lancet
, vol.2
, pp. 1358-1359
-
-
Buisseret, P.D.1
Pembrey, M.E.2
-
103
-
-
0021210072
-
Pi phenotypes in patients with ankylosing spondylitis, acute anterior uveitis, psoriasis and chronic prostatitis
-
Moller P, Fagerhol MK. Pi phenotypes in patients with ankylosing spondylitis, acute anterior uveitis, psoriasis and chronic prostatitis. Clin Genet 1984; 26:339-341.
-
(1984)
Clin Genet
, vol.26
, pp. 339-341
-
-
Moller, P.1
Fagerhol, M.K.2
-
105
-
-
0030849098
-
Ankylosing spondylitis and secretor status: A re-evaluation
-
Smith GW, James V, Mackenzie DA, et al. Ankylosing spondylitis and secretor status: a re-evaluation. Br J Rheumatol 1997; 36:778-780.
-
(1997)
Br J Rheumatol
, vol.36
, pp. 778-780
-
-
Smith, G.W.1
James, V.2
Mackenzie, D.A.3
-
106
-
-
0024678387
-
ABO blood group and secretor status in the spondyloarthropathies
-
Shinebaum R. ABO blood group and secretor status in the spondyloarthropathies. FEMS Microbiol Immunol 1989; 1:389-395.
-
(1989)
FEMS Microbiol Immunol
, vol.1
, pp. 389-395
-
-
Shinebaum, R.1
-
107
-
-
0036886367
-
Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis
-
Oxford
-
van der Paardt M, Crusius JB, Garcia-Gonzalez MA, et al. Interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in ankylosing spondylitis. Rheumatology (Oxford) 2002; 41:1419-1423.
-
(2002)
Rheumatology
, vol.41
, pp. 1419-1423
-
-
Van Der Paardt, M.1
Crusius, J.B.2
Garcia-Gonzalez, M.A.3
-
108
-
-
0035684706
-
A polymorphism within the interleukin 1 receptor antagonist (IL-1Ra) gene is associated with ankylosing spondylitis
-
Oxford
-
McGarry F, Neilly J, Anderson N, et al. A polymorphism within the interleukin 1 receptor antagonist (IL-1Ra) gene is associated with ankylosing spondylitis. Rheumatology (Oxford) 2001; 40:1359-1364.
-
(2001)
Rheumatology
, vol.40
, pp. 1359-1364
-
-
McGarry, F.1
Neilly, J.2
Anderson, N.3
-
109
-
-
0028913484
-
Cytokine production by normal human monocytes: Inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism
-
Danis VA, Millington M, Hyland VJ, Grennan D. Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism. Clin Exp Immunol 1995; 99:303-310.
-
(1995)
Clin Exp Immunol
, vol.99
, pp. 303-310
-
-
Danis, V.A.1
Millington, M.2
Hyland, V.J.3
Grennan, D.4
-
110
-
-
0031927564
-
IL-1 receptor antagonist (IL-1Ra) plasma levels are coordinately regulated by both IL-1Ra and IL-1beta genes
-
Hurme M, Santtila S. IL-1 receptor antagonist (IL-1Ra) plasma levels are coordinately regulated by both IL-1Ra and IL-1beta genes. Eur J Immunol 1998; 28:2598-2602.
-
(1998)
Eur J Immunol
, vol.28
, pp. 2598-2602
-
-
Hurme, M.1
Santtila, S.2
-
111
-
-
33744941999
-
IL-1 locus on chromosome 2q confers susceptibility on psoriatic arthritis
-
Rahman P, Peddle L, Sun S, et al. IL-1 locus on chromosome 2q confers susceptibility on psoriatic arthritis. Arthritis Rheum 2005; 52:S692.
-
(2005)
Arthritis Rheum
, vol.52
-
-
Rahman, P.1
Peddle, L.2
Sun, S.3
-
112
-
-
0035170976
-
Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: Its relation to HLA-B27 and influence of the TNF-308 gene polymorphism
-
Rudwaleit M, Siegert S, Yin Z, et al. Low T cell production of TNFalpha and IFNgamma in ankylosing spondylitis: its relation to HLA-B27 and influence of the TNF-308 gene polymorphism. Ann Rheum Dis 2001; 60:36-42.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 36-42
-
-
Rudwaleit, M.1
Siegert, S.2
Yin, Z.3
-
113
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273:1516-1517.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
114
-
-
0034660559
-
Searching for genetic determinants in the new millennium
-
Risch NJ. Searching for genetic determinants in the new millennium. Nature 2000; 405:847-856.
-
(2000)
Nature
, vol.405
, pp. 847-856
-
-
Risch, N.J.1
-
115
-
-
0042667153
-
Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis
-
Suzuki A, Yamada R, Chang X, et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat Genet 2003; 34:395-402.
-
(2003)
Nat Genet
, vol.34
, pp. 395-402
-
-
Suzuki, A.1
Yamada, R.2
Chang, X.3
-
116
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Begovich AB, Carlton VE, Honigberg LA, et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004; 75:330-337.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 330-337
-
-
Begovich, A.B.1
Carlton, V.E.2
Honigberg, L.A.3
-
117
-
-
4243129131
-
Linkage of osteoporosis to chromosome 20p12 and association to BMP2
-
Styrkarsdottir U, Cazier JB, Kong A, et al. Linkage of osteoporosis to chromosome 20p12 and association to BMP2. PLoS Biol 2003; 1:E69.
-
(2003)
PLoS Biol
, vol.1
-
-
Styrkarsdottir, U.1
Cazier, J.B.2
Kong, A.3
-
118
-
-
0242329880
-
Positional cloning of a novel gene influencing asthma from chromosome 2q14
-
Allen M, Heinzmann A, Noguchi E, et al. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet 2003; 35:258-263.
-
(2003)
Nat Genet
, vol.35
, pp. 258-263
-
-
Allen, M.1
Heinzmann, A.2
Noguchi, E.3
-
119
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex diseases
-
Botstein D, Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex diseases. Nature Genetics 2003; 33 (Suppl):228-237.
-
(2003)
Nature Genetics
, vol.33
, Issue.SUPPL.
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
|