Plasma folate as marker of folate status in epidemiological studies: The European Investigation into Cancer and Nutrition (EPIC)-Potsdam study

British Journal of Nutrition

Volumn 92, Issue 3, 2004, Pages 489-496

  Drogan, D ^a   Klipstein Grobusch, Kerstin ^a   Wans, S ^b   Luley, C ^b   Boeing, C ^a   Dierkes, J ^b  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Biomarker; EPIC study; Erythrocycte folate; Plasma folate; Polymorphism

Indexed keywords

COBALAMIN; CREATININE; FOLIC ACID; GAMMA GLUTAMYL HYDROLASE; HOMOCYSTEINE; METHYLENETETRAHYDROFOLIC ACID; PYRIDOXINE; REDUCED FOLATE CARRIER; BIOLOGICAL MARKER; CYANOCOBALAMIN; PYRIDOXAL 5 PHOSPHATE;

ADULT; ANTHROPOMETRY; ARTICLE; BLOOD SAMPLING; BODY MASS; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CORRELATION COEFFICIENT; DIETARY INTAKE; FEMALE; FOLIC ACID BLOOD LEVEL; FOOD INTAKE; GENETIC POLYMORPHISM; GENOTYPE; HEALTH STATUS; HEALTH SURVEY; HEMATOCRIT; HETEROZYGOSITY; HOMOZYGOSITY; HUMAN; HUMAN EXPERIMENT; MALE; MULTICENTER STUDY; PROSPECTIVE STUDY; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; VITAMIN SUPPLEMENTATION; AGE; BLOOD; CROSS-SECTIONAL STUDY; DIET; DIET SUPPLEMENTATION; ERYTHROCYTE; GENETICS; LIFESTYLE; METABOLISM; MIDDLE AGED;

ADULT; AGE FACTORS; BIOLOGICAL MARKERS; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; DIET; DIETARY SUPPLEMENTS; ERYTHROCYTES; FEMALE; FOLIC ACID; GENOTYPE; HOMOCYSTEINE; HUMANS; LIFE STYLE; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; PYRIDOXAL PHOSPHATE; PYRIDOXINE; VITAMIN B 12;

EID: 6944248069     PISSN: 00071145     EISSN: None     Source Type: Journal    
DOI: 10.1079/BJN20041211     Document Type: Article

References (44)

1. Afman LA, Trijbels FJ & Blom HJ (2003) The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans. J Nutr 133 75-77.
2. Bagley PJ & Selhub J (1998) A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. Proc Natl Acad Sci USA 95, 13217-13220.
3. Bailey LB & Gregory JF 3rd (1999) Folate metabolism and requirements. J Nutr 129, 779-782.
4. Bazzano LA, He J, Ogden LG, Loria C, Vupputuri S, Myers L & Whelton PK (2002) Dietary intake of folate and risk of stroke in US men and women: NHANES I Epidemiologic Follow-up Study. National Health and Nutrition Examination Survey. Stroke 33, 1183-1188.
5. Benton D, Haller J & Fordy J (1997) The vitamin status of young British adults. Int J Vitam Nutr Res 67, 34-40.
6. Boeing H, Bohlscheid-Thomas S, Voss S, Schneeweiss S & Wahrendorf J (1997) The relative validity of vitamin intakes derived from a food frequency questionnaire compared with 24-hour recalls and biological measurements: results from the EPIC pilot study in Germany. Int J Epidemiol 26, S82-S90.
7. Boeing H, Korfmann A & Bergmann MM (1999a) Recruitment procedures of EPIC-Germany. Ann Nutr Metab 43, 205-215.
8. Boeing H, Wahrendorf J & Becker N (1999b) EPIC-Germany - A source for studies into diet and risk of chronic diseases. Ann Nutr Metab 43, 195-204.
9. Bohlscheid-Thomas S, Hoting I, Boeing H & Wahrendorf J (1997a) Reproducibility and relative validity of energy and macronutrient intake of a food frequency questionnaire developed for the German part of the EPIC project. Int J Epidemiol 26, S71-S81.
10. Bohlscheid-Thomas S, Hoting I, Boeing H & Wahrendorf J (1997b) Reproducibility and relative validity of food group intake in a food frequency questionnaire developed for the German part of the EPIC project. Int J Epidemiol 26, S59-S70.
11. Chango A, Emery-Fillon N, de Courcy GP, Lambert D, Pfister M, Rosenblatt DS & Nicolas JP (2000) A polymorphism (80G → A) in the reduced folate carder gene and its associations with folate status and homocysteinemia. Mol Genet Metab 70, 310-315.
12. Deutsche Gesellschaft für Ernährung (2000) Referenzwerte für die Niihrstoffzufuhr, (Reference values for nutrient intake). 1. Auflage. Frankfurt/Main: Deutsche Gesellschaft für Ernährung.
13. Devlin AM, Ling EH, Peerson JM, Fernando S, Clarke R, Smith AD & Halsted CH (2000) Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum Mol Genet 9, 2837-2844.
14. Dierkes J, Domrose U, Bosselmann KP, Neumann KH & Luley C (2001a) Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease. J Ren Nutr 11, 67-72.
15. Dierkes J, Jeckel A, Ambrosch A, Westphal S, Luley C & Boeing H (2001b) Factors explaining the difference of total homocysteine between men and women in the European Investigation Into Cancer and Nutrition Potsdam study. Metabolism 50, 640-645.
16. Dierkes J, Kroesen M & Pietrzik K (1998) Folic acid and vitamin B6 supplementation and plasma homocysteine concentrations in healthy young women. Int J Vitam Nutr Res 68, 98-103.
17. Dumin JV & Womersley J (1974) Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr 32, 77-97.
18. Fairfield KM & Fletcher RH (2002) Vitamins for chronic disease prevention in adults: scientific review. J Am Med Assoc 287, 3116-3126.
19. Fodinger M, Dierkes J, Skoupy S, Rohrer C, Hagen W, Puttinger H, Hauser AC, Vychytil A & Sunder-Plassmann G (2003) Effect of glutamate carboxypeptidase II and reduced folate carrier polymorphisms on folate and total homocysteine concentrations in dialysis patients. J Am Soc Nephrol 14, 1314-1319.
20. Green TJ, Allen OB & O'Connor DL (1998) A three-day weighed food record and a semiquantitative food-frequency questionnaire are valid measures for assessing the folate and vitamin B-12 intakes of women aged 16 to 19 years. J Nutr 128, 1665-1671.
21. Herbert V (1982) Nutrition classics. Transactions of the Association of American Physicians, volume 75, 1962, pages 307-320. Experimental nutritional folate deficiency in man. Nutr Rev 40 246-248.
22. Jacques PF, Sulsky SI, Sadowski JA, Phillips JC, Rush D & Willett WC (1993) Comparison of micronutrient intake measured by a dietary questionnaire and biochemical indicators of micronutrient status. Am J Clin Nutr 57, 182-189.
23. Jaffe JP & Schilling RF (1991) Erythrocyte folate levels: a clinical study. Am J Hematol 36, 116-121.
24. Klemm C, Mathis G, Christ M, Gebhardt G, Hamami E, Pathasart B, Wagner U & Dehne LI (1999) Der BundesLebensmittel-Schlü ssel (BLS II.3) (The German Food Code and Nutrient Database). Berlin Bundesinstitut für Gesundheitlichen Verbraucherschutz und Veterinärmedizin.
25. Klerk M, Verhoef P, Clarke R, Blom HJ, Kok FJ & Schouten EG (2002) MTHFR 677C → T polymorphism and risk of coronary heart disease: a meta-analysis. J Am Med Assoc 288, 2023-2031.
26. Klipstein-Grobusch K, Georg T & Boeing H (1997) Interviewer variability in anthropometric measurements and estimates of body composition. Int J Epidemiol 26, S174-S180.
27. Kroke A, Klipstein-Grobusch K, Voss S, Moseneder J, Thielecke F, Noack R & Boeing H (1999) Validation of a self-administered food-frequency questionnaire administered in the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: comparison of energy, protein, and macronutrient intakes estimated with the doubly labeled water, urinary nitrogen, and repeated 24-h dietary recall methods. Am J Clin Nutr 70, 439-447.
28. Lievers KJ, Kluijtmans LA, Boers GH, Verhoef P, den Heijer M, Trijbels FJ & Blom HJ (2002) Influence of a glutamate carboxypeptidase II (GCPII) polymorphism (1561C → T) on plasma homocysteine, folate and vitamin B(12) levels and its relationship to cardiovascular disease risk. Atherosclerosis 164, 269-273.
29. McKinley MC, Strain JJ, McPartlin J, Scott JM & McNulty H (2001) Plasma homocysteine is not subject to seasonal variation. Clin Chem 47, 1430-1436.
30. Melse-Boonstra A, de Bree A, Verhoef P, Bjorke-Monsen AL & Verschuren WM (2002) Dietary monoglutamate and polyglutamate folate are associated with plasma folate concentrations in Dutch men and women aged 20-65 years. J Nutr 132, 1307-1312.
31. Molloy AM, Mills JL, Kirke PN, Whitehead AS, Weir DG & Scott JM (1998) Whole-blood folate values in subjects with different methylenetetrahydrofolate reductase genotypes: differences between the radioassay and microbiological assays. Clin Chem 44, 186-188.
32. Morrison HI, Schaubel D, Desmeules M & Wigle DT (1996) Serum folate and risk of fatal coronary heart disease. J Am Med Assoc 275, 1893-1896.
33. National Research Council (1989) Recommended Dietary Allowances, 10th ed. Washington, DC: National Academy of Sciences.
34. Phekoo K, Williams Y, Schey SA, Andrews VE, Dudley JM & Hoffbrand AV (1997) Folate assays: serum or red cell? J R Coll Physicians Lond 31, 291-295.
35. Pufulete M, Emery PW, Nelson M & Sanders TAB (2002) Validation of a short food frequency questionnaire to assess folate intake. Br J Nutr 87, 383-390.
36. Riboli E, Hunt KJ, Slimani N, Ferrari P, Norat T, Fahey M, Charrondière UR, Hémon B, Casagrande C & Vignat J (2002) European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr 5, 1113-1124.
37. Sauberlich HE (1999) Laboratory Tests for the Assessment of Nutritional Status, 2nd ed. Boca Raton, FL: CRC Press.
38. Suitor CW & Bailey LB (2000) Dietary folate equivalents: interpretation and application. J Am Diet Assoc 100, 88-94.
39. Thamm M, Mensink GB & Thierfelder W (1999) Folsaeureversorgung von Frauen im gebachrfachigen alter (Folic acid intake of women in childbearing age). Gesundheitswesen 61, S207- S212.
40. Vargas-Martinez C, Ordovas JM, Wilson PW & Selhub J (2002) The glutamate carboxypeptidase gene II (C → T) polymorphism does not affect folate status in the Framingham Offspring cohort. J Nutr 132, 1176-1179.
41. Ward M (2001) Homocysteine, folate, and cardiovascular disease. Int J Vitam Nutr Res 71, 173-178.
42. Whetstine JR, Gifford A J, Witt T, Liu XY, Flatley RM, Norris M, Haber M, Taub JW, Ravindranath Y & Matherly LH (2001) Single nucleotide polymorphisms in the human reduced folate carrier: characterization of a high-frequency G/A variant at position 80 and transport properties of the His(27) and Arg(27) carriers. Clin Cancer Res 7, 3416-3422.
43. Winkelmayer WC, Eberle C, Sunder-Plassmann G & Fodinger M (2003) Effects of the glutamate carboxypeptidase II (GCP2 1561C → T and reduced folate carrier (RFC1 80G → A) allelic variants on folate and total homocysteine levels in kidney transplant patients. Kidney Int 63, 2280-2285.
44. Xiao W & Oefner PJ (2001) Denaturing high-performance liquid chromatography: a review. Hum Mutat 17, 439-474.