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Volumn 48, Issue 1, 2006, Pages 814-819

Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction

Author keywords

Cerebral arteries; Endothelium; Hypoxia reoxygenation; Nitric oxide (NO); Rho kinase

Indexed keywords

3,3 BIS(2 AMINOETHYL) 1 HYDROXY 2 OXOTRIAZENE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCHOLINE; ARGININE; CHELERYTHRINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRATE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; RHO KINASE; RHO KINASE INHIBITOR; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 33747751531     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.fjc.0000211797.52905.52     Document Type: Article
Times cited : (4)

References (41)
  • 1
    • 24144498411 scopus 로고    scopus 로고
    • Rho-Kinase is important therapeutic target in cardiovascular medicine
    • Shimokawa H, Takeshita A. Rho-Kinase is important therapeutic target in cardiovascular medicine. Arterioscler Thromb Vasc Biol. 2005;25:1767-1775.
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1767-1775
    • Shimokawa, H.1    Takeshita, A.2
  • 2
    • 0034650714 scopus 로고    scopus 로고
    • Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II
    • Somlyo AP, Somlyo AV. Signal transduction by G-proteins, Rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II. J Physiol. 2000;522:177-185.
    • (2000) J Physiol , vol.522 , pp. 177-185
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 3
    • 0035838950 scopus 로고    scopus 로고
    • Pharmacological profile of hydroxy fasudil as a selective Rho-kinase inhibitor on ischemic brain damage
    • Satoh S, Utsunomiya T, Tsurui K, et al. Pharmacological profile of hydroxy fasudil as a selective Rho-kinase inhibitor on ischemic brain damage. Life Sci. 2001;69:1441-1453.
    • (2001) Life Sci , vol.69 , pp. 1441-1453
    • Satoh, S.1    Utsunomiya, T.2    Tsurui, K.3
  • 4
    • 26444518165 scopus 로고    scopus 로고
    • Inhibition of Rho-kinase (ROCK) leads to increased cerebral blood flow and stroke protection
    • Rikitake Y, Kim HH, Huang Z, et al. Inhibition of Rho-kinase (ROCK) leads to increased cerebral blood flow and stroke protection. Stroke. 2005;36:2251-2257.
    • (2005) Stroke , vol.36 , pp. 2251-2257
    • Rikitake, Y.1    Kim, H.H.2    Huang, Z.3
  • 5
    • 0030005713 scopus 로고    scopus 로고
    • Angiotensin II mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: Contribution to alterations of vasomotor tone
    • Rajagopalan S, Kurz S, Münzel T, et al. Angiotensin II mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest. 1996;97:1916-1923.
    • (1996) J Clin Invest , vol.97 , pp. 1916-1923
    • Rajagopalan, S.1    Kurz, S.2    Münzel, T.3
  • 6
    • 0007321633 scopus 로고    scopus 로고
    • Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension
    • Wang HD, Hope S, Du Y, et al. Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension. Hypertension. 1999;33:1225-1232.
    • (1999) Hypertension , vol.33 , pp. 1225-1232
    • Wang, H.D.1    Hope, S.2    Du, Y.3
  • 7
    • 0043124266 scopus 로고    scopus 로고
    • Angiotensin II produces superoxide-mediated impairment of endothelial function in cerebral arterioles
    • Didion SP, Faraci FM. Angiotensin II produces superoxide-mediated impairment of endothelial function in cerebral arterioles. Stroke. 2003;34:2038-2042.
    • (2003) Stroke , vol.34 , pp. 2038-2042
    • Didion, S.P.1    Faraci, F.M.2
  • 8
    • 18044388568 scopus 로고    scopus 로고
    • Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice
    • Yan C, Huang A, Wu Z, et al. Increased superoxide leads to decreased flow-induced dilation in resistance arteries of Mn-SOD-deficient mice. Am J Physiol Heart Circ Physiol. 2005;288:H2225-H2231.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288
    • Yan, C.1    Huang, A.2    Wu, Z.3
  • 9
    • 4744347777 scopus 로고    scopus 로고
    • Activation of Rho/Rho-kinase signaling pathway by reactive oxygen species in rat aorta
    • Jin LM, Ying ZK, Webb RC. Activation of Rho/Rho-kinase signaling pathway by reactive oxygen species in rat aorta. Am J Physiol Heart Circ Physiol. 2004;287:H1495-H1500.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287
    • Jin, L.M.1    Ying, Z.K.2    Webb, R.C.3
  • 10
    • 0142120102 scopus 로고    scopus 로고
    • Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: Effect on endothelial NAD(P)H oxidase system
    • Higashi M, Shimokawa H, Hattori T, et al. Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system. Circ Res. 2003;93:767-775.
    • (2003) Circ Res , vol.93 , pp. 767-775
    • Higashi, M.1    Shimokawa, H.2    Hattori, T.3
  • 11
    • 0036181829 scopus 로고    scopus 로고
    • Nitric oxide induces dilation of rat aorta via inhibition of Rho-kinase signaling
    • Chitaley K, Webb RC. Nitric oxide induces dilation of rat aorta via inhibition of Rho-kinase signaling. Hypertension. 2002;39:438-442.
    • (2002) Hypertension , vol.39 , pp. 438-442
    • Chitaley, K.1    Webb, R.C.2
  • 13
    • 0034810237 scopus 로고    scopus 로고
    • cGMP-dependent protein kinase phosphorylates and inactivates RhoA
    • Sawada N, Itoh H, Yamashita J, et al. cGMP-dependent protein kinase phosphorylates and inactivates RhoA. Biochem Biophys Res Commun. 2001;280:798-805.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 798-805
    • Sawada, N.1    Itoh, H.2    Yamashita, J.3
  • 14
    • 18244398919 scopus 로고    scopus 로고
    • NF-κB activation plays a role in superoxide-mediated cerebral endothelial dysfunction after hypoxia/ reoxygenation
    • Xie H, Ray PE, Short BL. NF-κB activation plays a role in superoxide-mediated cerebral endothelial dysfunction after hypoxia/ reoxygenation. Stroke. 2005;36:1047-1052.
    • (2005) Stroke , vol.36 , pp. 1047-1052
    • Xie, H.1    Ray, P.E.2    Short, B.L.3
  • 15
    • 3242730347 scopus 로고    scopus 로고
    • Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells
    • Hiroki J, Shimokawa H, Higashi M, et al. Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells. J Mol Cell Cardiol. 2004;37:537-546.
    • (2004) J Mol Cell Cardiol , vol.37 , pp. 537-546
    • Hiroki, J.1    Shimokawa, H.2    Higashi, M.3
  • 16
    • 0030656619 scopus 로고    scopus 로고
    • Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
    • Uehata M, Ishizaki T, Satoh H, et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature. 1997;389:990-994.
    • (1997) Nature , vol.389 , pp. 990-994
    • Uehata, M.1    Ishizaki, T.2    Satoh, H.3
  • 17
    • 0034017744 scopus 로고    scopus 로고
    • Pharmacological properties of Y-27632, a specific inhibitor of Rho-associated kinases
    • Ishizaki T, Uehata M, Tamechika I, et al. Pharmacological properties of Y-27632, a specific inhibitor of Rho-associated kinases. Mol Pharmacol. 2000;57:976-983.
    • (2000) Mol Pharmacol , vol.57 , pp. 976-983
    • Ishizaki, T.1    Uehata, M.2    Tamechika, I.3
  • 18
    • 33751385555 scopus 로고
    • New nitric oxide-releasing zwitterions derived from polyamines
    • Hrabie JA, Klosie JR, Wink DA. New nitric oxide-releasing zwitterions derived from polyamines. J Org Chem. 1993;58:1472-1476.
    • (1993) J Org Chem , vol.58 , pp. 1472-1476
    • Hrabie, J.A.1    Klosie, J.R.2    Wink, D.A.3
  • 19
    • 0027379589 scopus 로고
    • Nitric oxide/nucleophile complexes: A unique class of nitric oxide-based vasodilators
    • Morley D, Keefer LK. Nitric oxide/nucleophile complexes: a unique class of nitric oxide-based vasodilators. J Cardiovasc Pharmacol. 1993;22:S3-S9.
    • (1993) J Cardiovasc Pharmacol , vol.22
    • Morley, D.1    Keefer, L.K.2
  • 20
    • 0021882351 scopus 로고
    • Influence of transmural pressure on myogenic responses of isolated cerebral arteries of the rat
    • Halpern W, Osol G. Influence of transmural pressure on myogenic responses of isolated cerebral arteries of the rat. Ann Biomed Eng. 1985;13:287-293.
    • (1985) Ann Biomed Eng , vol.13 , pp. 287-293
    • Halpern, W.1    Osol, G.2
  • 21
    • 0032751372 scopus 로고    scopus 로고
    • Oxidized low-density lipoprotein enhances myogenic tone in the rabbit posterior cerebral artery through the release of endothelin-1
    • Xie H, Bevan JA. Oxidized low-density lipoprotein enhances myogenic tone in the rabbit posterior cerebral artery through the release of endothelin-1. Stroke. 1999;30:2423-2430.
    • (1999) Stroke , vol.30 , pp. 2423-2430
    • Xie, H.1    Bevan, J.A.2
  • 23
    • 0032824872 scopus 로고    scopus 로고
    • Constriction to hypoxia-reoxygenation in isolated mouse coronary arteries: Role of endothelium and superoxide
    • Liu Q. Constriction to hypoxia-reoxygenation in isolated mouse coronary arteries: role of endothelium and superoxide. J Appl Physiol. 1999;87:1392-1396.
    • (1999) J Appl Physiol , vol.87 , pp. 1392-1396
    • Liu, Q.1
  • 24
    • 0035957574 scopus 로고    scopus 로고
    • Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: Comparison with protein kinase C
    • Chrissobolis S, Sobey CG. Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C. Circ Res. 2001;88:774-779.
    • (2001) Circ Res , vol.88 , pp. 774-779
    • Chrissobolis, S.1    Sobey, C.G.2
  • 25
    • 0942287333 scopus 로고    scopus 로고
    • Testosterone suppresses endothelium-dependent dilation of rat middle cerebral arteries
    • Gonzales RJ, Krause DN, Duckles SP. Testosterone suppresses endothelium-dependent dilation of rat middle cerebral arteries. Am J Physiol Heart Circ Physiol. 2004;286:H552-H560.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Gonzales, R.J.1    Krause, D.N.2    Duckles, S.P.3
  • 26
    • 0030771869 scopus 로고    scopus 로고
    • Estrogen and selective estrogen receptor modulator LY117018 enhance release of nitric oxide in rat aorta
    • Rahimian R, Laher I, Dube G, et al. Estrogen and selective estrogen receptor modulator LY117018 enhance release of nitric oxide in rat aorta. J Pharmacol Exp Ther. 1997;283:116-122.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 116-122
    • Rahimian, R.1    Laher, I.2    Dube, G.3
  • 27
    • 0034032826 scopus 로고    scopus 로고
    • Conditions permitting suppression of stretch-induced and vasoconstrictor tone by basal nitric oxide activity in porcine cerebral artery
    • Wallis SJ, Martin W. Conditions permitting suppression of stretch-induced and vasoconstrictor tone by basal nitric oxide activity in porcine cerebral artery. Br J Pharmacol. 2000;130:567-574.
    • (2000) Br J Pharmacol , vol.130 , pp. 567-574
    • Wallis, S.J.1    Martin, W.2
  • 28
    • 16844378483 scopus 로고    scopus 로고
    • Venoarterial extracorporeal membrane oxygenation (VA ECMO) impairs basal nitric oxide production in cerebral arteries of newborn lambs
    • Ingyinn M, Lee J, Short BL, et al. Venoarterial extracorporeal membrane oxygenation (VA ECMO) impairs basal nitric oxide production in cerebral arteries of newborn lambs. Pediatr Crit Care Med. 2000;1:161-165.
    • (2000) Pediatr Crit Care Med , vol.1 , pp. 161-165
    • Ingyinn, M.1    Lee, J.2    Short, B.L.3
  • 29
    • 11244319589 scopus 로고    scopus 로고
    • Estrogen receptor activation of phosphoinositide-3 kinase, Akt, and nitric oxide signaling in cerebral blood vessels: Rapid and long-term effects
    • Stirone C, Boroujerdi A, Duckles SP, et al. Estrogen receptor activation of phosphoinositide-3 kinase, Akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects. Mol Pharmacol. 2005;67:105-113.
    • (2005) Mol Pharmacol , vol.67 , pp. 105-113
    • Stirone, C.1    Boroujerdi, A.2    Duckles, S.P.3
  • 30
    • 0032780860 scopus 로고    scopus 로고
    • Heterogeneity of endothelium-dependent vasodilation in pressurized cerebral and small mesenteric resistance arteries of the rat
    • Lagaud GJ, Skarsgard PL, Laher I, et al. Heterogeneity of endothelium-dependent vasodilation in pressurized cerebral and small mesenteric resistance arteries of the rat. J Pharmacol Exp Ther. 1999;290:832-839.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 832-839
    • Lagaud, G.J.1    Skarsgard, P.L.2    Laher, I.3
  • 31
    • 13544260622 scopus 로고    scopus 로고
    • Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reper-fusion injury in canine coronary microcirculation in vivo
    • Yada T, Shimokawa H, Hiramatsu O, et al. Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reper-fusion injury in canine coronary microcirculation in vivo. J Am Coll Cardiol. 2005;45:599-607.
    • (2005) J Am Coll Cardiol , vol.45 , pp. 599-607
    • Yada, T.1    Shimokawa, H.2    Hiramatsu, O.3
  • 32
    • 8844249337 scopus 로고    scopus 로고
    • Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion-induced acute renal failure in rats
    • Teraishi K, Kurata H, Nakajima A, et al. Preventive effect of Y-27632, a selective Rho-kinase inhibitor, on ischemia/reperfusion-induced acute renal failure in rats. Eur J Pharmacol. 2004;505:205-211.
    • (2004) Eur J Pharmacol , vol.505 , pp. 205-211
    • Teraishi, K.1    Kurata, H.2    Nakajima, A.3
  • 33
    • 0033879562 scopus 로고    scopus 로고
    • Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm
    • Sato M, Tani E, Fujikawa H, et al. Involvement of Rho-kinase-mediated phosphorylation of myosin light chain in enhancement of cerebral vasospasm. Circ Res. 2000;87:195-200.
    • (2000) Circ Res , vol.87 , pp. 195-200
    • Sato, M.1    Tani, E.2    Fujikawa, H.3
  • 34
    • 17644405456 scopus 로고    scopus 로고
    • Effects of Rho-kinase inhibition on cerebral artery myogenic tone and reactivity
    • Gokina NI, Park KM, McElroy-Yaggy K, et al. Effects of Rho-kinase inhibition on cerebral artery myogenic tone and reactivity. J Appl Physiol. 2005;98:1940-1948.
    • (2005) J Appl Physiol , vol.98 , pp. 1940-1948
    • Gokina, N.I.1    Park, K.M.2    McElroy-Yaggy, K.3
  • 35
    • 0036645303 scopus 로고    scopus 로고
    • Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase
    • Takemoto M, Sun J, Hiroki J, et al. Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase. Circulation. 2002;106:57-62.
    • (2002) Circulation , vol.106 , pp. 57-62
    • Takemoto, M.1    Sun, J.2    Hiroki, J.3
  • 36
    • 0031863253 scopus 로고    scopus 로고
    • Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion
    • Marrelli SP, Johnson TD, Khorovets A, et al. Altered function of inward rectifier potassium channels in cerebrovascular smooth muscle after ischemia/reperfusion. Stroke. 1998;29:1469-1474.
    • (1998) Stroke , vol.29 , pp. 1469-1474
    • Marrelli, S.P.1    Johnson, T.D.2    Khorovets, A.3
  • 37
    • 0141794172 scopus 로고    scopus 로고
    • Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1
    • Jones SV. Role of the small GTPase Rho in modulation of the inwardly rectifying potassium channel Kir2.1. Mol Pharmacol. 2003;64:987-993.
    • (2003) Mol Pharmacol , vol.64 , pp. 987-993
    • Jones, S.V.1
  • 38
    • 9144268981 scopus 로고    scopus 로고
    • RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65
    • Anwar KN, Fazal F, Malik AB, et al. RhoA/Rho-associated kinase pathway selectively regulates thrombin-induced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65. J Immunol. 2004;173:6965-6972.
    • (2004) J Immunol , vol.173 , pp. 6965-6972
    • Anwar, K.N.1    Fazal, F.2    Malik, A.B.3
  • 39
    • 0035061658 scopus 로고    scopus 로고
    • Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury
    • Pluta RM, Rak R, Wink DA, et al. Effects of nitric oxide on reactive oxygen species production and infarction size after brain reperfusion injury. Neurosurgery. 2001;48:884-892.
    • (2001) Neurosurgery , vol.48 , pp. 884-892
    • Pluta, R.M.1    Rak, R.2    Wink, D.A.3
  • 40
    • 0028079874 scopus 로고
    • NO donor SIN-1 protects against reoxygenation-induced cardiomyocyte injury by a dual action
    • Schluter KD, Weber M, Schraven E, et al. NO donor SIN-1 protects against reoxygenation-induced cardiomyocyte injury by a dual action. Am J Physiol. 1994;267:H1461-H1466.
    • (1994) Am J Physiol , vol.267
    • Schluter, K.D.1    Weber, M.2    Schraven, E.3
  • 41
    • 0038338555 scopus 로고    scopus 로고
    • Nitric oxide-mediated decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho-kinase pathway
    • Bolz SS, Vogel L, Sollinger D, et al. Nitric oxide-mediated decrease in calcium sensitivity of resistance arteries is attributable to activation of the myosin light chain phosphatase and antagonized by the RhoA/Rho-kinase pathway. Circulation. 2003;107:3081-3087.
    • (2003) Circulation , vol.107 , pp. 3081-3087
    • Bolz, S.S.1    Vogel, L.2    Sollinger, D.3


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