메뉴 건너뛰기




Volumn 20, Issue 9, 2006, Pages 1582-1592

MN1-TEL, the product of the t(12;22) in human myeloid leukemia, immortalizes murine myeloid cells and causes myeloid malignancy in mice

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; ONCOPROTEIN; PROTEIN MN1 TEL; RETROVIRUS VECTOR; STEM CELL FACTOR; UNCLASSIFIED DRUG;

EID: 33747599160     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2404298     Document Type: Article
Times cited : (14)

References (44)
  • 1
    • 17044429678 scopus 로고    scopus 로고
    • ETV6: A versatile player in leukemogenesis
    • Bohlander SK. ETV6: A versatile player in leukemogenesis. Semin Cancer Biol 2005; 15: 162-174.
    • (2005) Semin Cancer Biol , vol.15 , pp. 162-174
    • Bohlander, S.K.1
  • 2
    • 0032898523 scopus 로고    scopus 로고
    • The role of TEL fusion genes in pediatric leukemias
    • Rubnitz JE, Pui CH, Downing JR. The role of TEL fusion genes in pediatric leukemias. Leukemia 1999; 13: 6-13.
    • (1999) Leukemia , vol.13 , pp. 6-13
    • Rubnitz, J.E.1    Pui, C.H.2    Downing, J.R.3
  • 3
    • 0028224348 scopus 로고
    • Fusion of PDGF receptor beta to a novel ETS-like gene, TEL, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation
    • Golub TR, Barker GF, Lovett M, Gilliland DG. Fusion of PDGF receptor beta to a novel ETS-like gene, TEL, in chronic myelomonocytic leukemia with t(5;12) chromosomal translocation. Cell 1994; 77: 307-316.
    • (1994) Cell , vol.77 , pp. 307-316
    • Golub, T.R.1    Barker, G.F.2    Lovett, M.3    Gilliland, D.G.4
  • 5
    • 17144463437 scopus 로고    scopus 로고
    • A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFRb oncoprotein
    • Jousset C, Carron C, Boureux A, TranQuang C, Oury C, Dusanter-Fourt I et al. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFRb oncoprotein. EMBO J 1997; 16: 69-82.
    • (1997) EMBO J , vol.16 , pp. 69-82
    • Jousset, C.1    Carron, C.2    Boureux, A.3    TranQuang, C.4    Oury, C.5    Dusanter-Fourt, I.6
  • 6
  • 7
    • 0342646965 scopus 로고    scopus 로고
    • Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6
    • Potter M, Buijs A, Kreider B, Rompaey LV, Grosveld G. Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ ETV6. Blood 2000; 95: 3341-3348.
    • (2000) Blood , vol.95 , pp. 3341-3348
    • Potter, M.1    Buijs, A.2    Kreider, B.3    Rompaey, L.V.4    Grosveld, G.5
  • 9
    • 0033517711 scopus 로고    scopus 로고
    • The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A
    • Chakrabarti SR, Nucifora G. The leukemia-associated gene TEL encodes a transcription repressor which associates with SMRT and mSin3A. Biochem Biophys Res Common 1999; 264: 871-877.
    • (1999) Biochem Biophys Res Common , vol.264 , pp. 871-877
    • Chakrabarti, S.R.1    Nucifora, G.2
  • 11
    • 0034461081 scopus 로고    scopus 로고
    • The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity
    • Buijs A, van Rompaey L, Molijn AC, Davis JN, Vertegaal AC, Potter MD et al. The MN1-TEL fusion protein, encoded by the translocation (12;22)(p13;q11) in myeloid leukemia, is a transcription factor with transforming activity. Mol Cell Biol 2000; 20: 9281-9293.
    • (2000) Mol Cell Biol , vol.20 , pp. 9281-9293
    • Buijs, A.1    van Rompaey, L.2    Molijn, A.C.3    Davis, J.N.4    Vertegaal, A.C.5    Potter, M.D.6
  • 12
    • 0034665729 scopus 로고    scopus 로고
    • DNA binding specificity studies of four ETS proteins support an indirect read-out mechanism of protein-DNA recognition
    • Szymczyna BR, Arrowsmith CH. DNA binding specificity studies of four ETS proteins support an indirect read-out mechanism of protein-DNA recognition. J Biol Chem 2000; 275: 28363-28370.
    • (2000) J Biol Chem , vol.275 , pp. 28363-28370
    • Szymczyna, B.R.1    Arrowsmith, C.H.2
  • 13
    • 0032717039 scopus 로고    scopus 로고
    • The role of chromosome translocations in leukemogenesis
    • Rowley JD. The role of chromosome translocations in leukemogenesis. Semin Hematol 1999; 36: 59-72.
    • (1999) Semin Hematol , vol.36 , pp. 59-72
    • Rowley, J.D.1
  • 15
    • 15444339209 scopus 로고    scopus 로고
    • A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
    • Lacronique V, Boureux A, Valle VD, Poirel H, Quang CT, Mauchauffe M et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science 1997; 278: 1309-1312.
    • (1997) Science , vol.278 , pp. 1309-1312
    • Lacronique, V.1    Boureux, A.2    Valle, V.D.3    Poirel, H.4    Quang, C.T.5    Mauchauffe, M.6
  • 16
    • 0032778537 scopus 로고    scopus 로고
    • The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): Molecular cloning of both reciprocal transcripts
    • Cazzaniga G, Tosi S, Aloisi A, Giudici G, Daniotti M, Pioltelli P et al. The tyrosine kinase abl-related gene ARG is fused to ETV6 in an AML-M4Eo patient with a t(1;12)(q25;p13): Molecular cloning of both reciprocal transcripts. Blood 1999; 94: 4370-4373.
    • (1999) Blood , vol.94 , pp. 4370-4373
    • Cazzaniga, G.1    Tosi, S.2    Aloisi, A.3    Giudici, G.4    Daniotti, M.5    Pioltelli, P.6
  • 17
    • 0031953233 scopus 로고    scopus 로고
    • A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma
    • Knezevich S, McFadden D, Tao W, Lim J, Sorensen P. A novel ETV6-NTRK3 gene fusion in congenital fibrosarcoma. Nat Genet 1998; 18: 184-187.
    • (1998) Nat Genet , vol.18 , pp. 184-187
    • Knezevich, S.1    McFadden, D.2    Tao, W.3    Lim, J.4    Sorensen, P.5
  • 18
    • 19044391610 scopus 로고    scopus 로고
    • Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma
    • Tognon C, Knezevich SR, Huntsman D, Roskelley CD, Melnyk N, Mathers JA et al. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell 2002; 2: 367-376.
    • (2002) Cancer Cell , vol.2 , pp. 367-376
    • Tognon, C.1    Knezevich, S.R.2    Huntsman, D.3    Roskelley, C.D.4    Melnyk, N.5    Mathers, J.A.6
  • 20
    • 0030070288 scopus 로고    scopus 로고
    • Involvement of the TEL gene in hematologic malignancy by diverse molecular genetic mechanisms
    • Golub TR, Barker GF, Stegmaier K, Gilliland DG. Involvement of the TEL gene in hematologic malignancy by diverse molecular genetic mechanisms. Curr Top Microbiol Immunol 1996; 211: 279-288.
    • (1996) Curr Top Microbiol Immunol , vol.211 , pp. 279-288
    • Golub, T.R.1    Barker, G.F.2    Stegmaier, K.3    Gilliland, D.G.4
  • 21
    • 0034678609 scopus 로고    scopus 로고
    • Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia
    • Liu Q, Schwaller J, Kutok J, Cain D, Aster JC, Williams IR et al. Signal transduction and transforming properties of the TEL-TRKC fusions associated with t(12;15)(p13;q25) in congenital fibrosarcoma and acute myelogenous leukemia. EMBO J 2000; 19: 1827-1838.
    • (2000) EMBO J , vol.19 , pp. 1827-1838
    • Liu, Q.1    Schwaller, J.2    Kutok, J.3    Cain, D.4    Aster, J.C.5    Williams, I.R.6
  • 22
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller J, Frantsve J, Aster J, Williams IR, Tomasson MH, Ross TS et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J 1998; 17: 5321-5333.
    • (1998) EMBO J , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3    Williams, I.R.4    Tomasson, M.H.5    Ross, T.S.6
  • 23
    • 0033604460 scopus 로고    scopus 로고
    • Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein
    • Sjoblom T, Boureux A, Ronnstrand L, Heldin CH, Ghysdael J, Ostman A. Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein. Oncogene 1999; 18: 7055-7062.
    • (1999) Oncogene , vol.18 , pp. 7055-7062
    • Sjoblom, T.1    Boureux, A.2    Ronnstrand, L.3    Heldin, C.H.4    Ghysdael, J.5    Ostman, A.6
  • 24
    • 0033084227 scopus 로고    scopus 로고
    • TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor
    • Tomasson MH, Williams IR, Hasserjian R, Udomsakdi C, McGrath SM, Schwaller J et al. TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor. Blood 1999; 93: 1707-1714.
    • (1999) Blood , vol.93 , pp. 1707-1714
    • Tomasson, M.H.1    Williams, I.R.2    Hasserjian, R.3    Udomsakdi, C.4    McGrath, S.M.5    Schwaller, J.6
  • 25
    • 0031043018 scopus 로고    scopus 로고
    • Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter
    • Fears S, Gavin M, Zhang D, Hetherinton C, Ben-David Y, Rowley J et al. Functional characterization of ETV6 and ETV6/CBFA2 in the regulation of the MCSFR proximal promoter. Proc Natl Acad Sci USA 1997; 94: 1949-1954.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 1949-1954
    • Fears, S.1    Gavin, M.2    Zhang, D.3    Hetherinton, C.4    Ben-David, Y.5    Rowley, J.6
  • 26
    • 0032433144 scopus 로고    scopus 로고
    • Role of histone deacetylases in acute leukemia
    • Fenrick R, Hiebert SW. Role of histone deacetylases in acute leukemia. J Cell Biochem Suppl 1998; 30-31: 194-202.
    • (1998) J Cell Biochem Suppl , vol.30-31 , pp. 194-202
    • Fenrick, R.1    Hiebert, S.W.2
  • 27
    • 9044231364 scopus 로고    scopus 로고
    • The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription
    • Hiebert SW, Sun W, Davis JN, Golub T, Shurtleff S, Buijs A et al. The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription. Mol Cell Biol 1996; 16: 1349-1355.
    • (1996) Mol Cell Biol , vol.16 , pp. 1349-1355
    • Hiebert, S.W.1    Sun, W.2    Davis, J.N.3    Golub, T.4    Shurtleff, S.5    Buijs, A.6
  • 28
    • 0031450875 scopus 로고    scopus 로고
    • The EVI1 gene in myeloid leukemia
    • Nucifora G. The EVI1 gene in myeloid leukemia. Leukemia 1997; 11: 2022-2031.
    • (1997) Leukemia , vol.11 , pp. 2022-2031
    • Nucifora, G.1
  • 29
    • 0032904241 scopus 로고    scopus 로고
    • Fusion of ETV6 to the caudal-related homeobox gene CDX2 in acute myeloid leukemia with the t(12;13)(p13;q21)
    • Chase A, Reiter A, Burci L, Cazzaniga G, Biondi A, Pickard J et al. Fusion of ETV6 to the caudal-related homeobox gene CDX2 in acute myeloid leukemia with the t(12;13)(p13;q21). Blood 1999; 93: 1025-1031.
    • (1999) Blood , vol.93 , pp. 1025-1031
    • Chase, A.1    Reiter, A.2    Burci, L.3    Cazzaniga, G.4    Biondi, A.5    Pickard, J.6
  • 30
    • 0035878943 scopus 로고    scopus 로고
    • Fusion of the homeobox gene HLXB9 and the ETV6 gene in infant acute myeloid leukemias with the t(7;12)(q36;pl3)
    • Beverloo HB, Panagopoulos I, Isaksson M, van Wering E, van Drunen E, de Klein A et al. Fusion of the homeobox gene HLXB9 and the ETV6 gene in infant acute myeloid leukemias with the t(7;12)(q36;pl3). Cancer Res 2001; 61: 5374-5377.
    • (2001) Cancer Res , vol.61 , pp. 5374-5377
    • Beverloo, H.B.1    Panagopoulos, I.2    Isaksson, M.3    van Wering, E.4    van Drunen, E.5    de Klein, A.6
  • 31
    • 0035875036 scopus 로고    scopus 로고
    • The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case
    • Cazzaniga G, Daniotti M, Tosi S, Giudici G, Aloisi A, Pogliani E et al. The paired box domain gene PAX5 is fused to ETV6/TEL in an acute lymphoblastic leukemia case. Cancer Res 2001; 61: 4666-4670.
    • (2001) Cancer Res , vol.61 , pp. 4666-4670
    • Cazzaniga, G.1    Daniotti, M.2    Tosi, S.3    Giudici, G.4    Aloisi, A.5    Pogliani, E.6
  • 32
    • 0033199749 scopus 로고    scopus 로고
    • Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13)
    • Cools J, Bilhou-Nabera C, Wlodarska I, Cabrol C, Talmant P, Bernard P et al. Fusion of a novel gene, BTL, to ETV6 in acute myeloid leukemias with a t(4;12)(q11-q12;p13). Blood 1999; 94: 1820-1824.
    • (1999) Blood , vol.94 , pp. 1820-1824
    • Cools, J.1    Bilhou-Nabera, C.2    Wlodarska, I.3    Cabrol, C.4    Talmant, P.5    Bernard, P.6
  • 33
    • 0029026395 scopus 로고
    • Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma
    • Lekanne Deprez RH, Riegman PH, Groen NA, Warringa UL, van Biezen NA, Molijn AC et al. Cloning and characterization of MN1, a gene from chromosome 22q11, which is disrupted by a balanced translocation in a meningioma. Oncogene 1995; 10: 1521-1528.
    • (1995) Oncogene , vol.10 , pp. 1521-1528
    • Lekanne Deprez, R.H.1    Riegman, P.H.2    Groen, N.A.3    Warringa, U.L.4    van Biezen, N.A.5    Molijn, A.C.6
  • 35
    • 28844442337 scopus 로고    scopus 로고
    • Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9
    • Kawagoe H, Grosveld GC. Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. Blood 2005; 106: 4269-4277.
    • (2005) Blood , vol.106 , pp. 4269-4277
    • Kawagoe, H.1    Grosveld, G.C.2
  • 36
    • 28844508272 scopus 로고    scopus 로고
    • MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice
    • Kawagoe H, Grosveld GC. MN1-TEL myeloid oncoprotein expressed in multipotent progenitors perturbs both myeloid and lymphoid growth and causes T-lymphoid tumors in mice. Blood 2005; 106: 4278-4286.
    • (2005) Blood , vol.106 , pp. 4278-4286
    • Kawagoe, H.1    Grosveld, G.C.2
  • 40
    • 0028062043 scopus 로고
    • Diffusible factors from the murine cell line M2-10B4 support human in vitro hematopoiesis
    • Burroughs J, Gupta P, Blazar BR, Verfaillie CM. Diffusible factors from the murine cell line M2-10B4 support human in vitro hematopoiesis. Exp Hematol 1994; 22: 1095-1101.
    • (1994) Exp Hematol , vol.22 , pp. 1095-1101
    • Burroughs, J.1    Gupta, P.2    Blazar, B.R.3    Verfaillie, C.M.4
  • 41
    • 0036463950 scopus 로고    scopus 로고
    • Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia
    • Higuchi M, O'Brien D, Kumaravelu P, Lenny N, Yeoh EJ, Downing JR. Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia. Cancer Cell 2002; 1: 63-74.
    • (2002) Cancer Cell , vol.1 , pp. 63-74
    • Higuchi, M.1    O'Brien, D.2    Kumaravelu, P.3    Lenny, N.4    Yeoh, E.J.5    Downing, J.R.6
  • 42
    • 0030791974 scopus 로고    scopus 로고
    • Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL
    • Lavau C, Szilvassy SJ, Slany R, Cleary ML. Immortalization and leukemic transformation of a myelomonocytic precursor by retrovirally transduced HRX-ENL. EMBO J 1997; 16: 4226-4237.
    • (1997) EMBO J , vol.16 , pp. 4226-4237
    • Lavau, C.1    Szilvassy, S.J.2    Slany, R.3    Cleary, M.L.4
  • 44
    • 0035930726 scopus 로고    scopus 로고
    • A transcriptional switch mediated by cofactor methylation
    • Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM et al. A transcriptional switch mediated by cofactor methylation. Science 2001; 294: 2507-2511.
    • (2001) Science , vol.294 , pp. 2507-2511
    • Xu, W.1    Chen, H.2    Du, K.3    Asahara, H.4    Tini, M.5    Emerson, B.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.