Effect of alkyl groups on the cellular hydrolysis of stavudine phosphoramidates

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 18, 2006, Pages 6420-6433

  Venkatachalam, T K ^a   Sarquis, M ^a   Qazi, S ^a   Uckun, F M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

Alkyl groups; Cellular hydrolysis; Stavudine phosphoramides

Indexed keywords

ALKYL GROUP; AMINO ACID; BACTERIAL ENZYME; ESTER DERIVATIVE; METHYL GROUP; PHOSPHORUS DERIVATIVE; STAVUDINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL LINE; CELL METABOLISM; CELL TYPE; CHIRALITY; CONTROLLED STUDY; DENSITY; ELECTRON; HUMAN; HUMAN CELL; HYDROLYSIS; MOUSE; NONHUMAN; STEREOSPECIFICITY; SUBSTITUTION REACTION;

AMIDES; ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; ESTERASES; HUMANS; HYDROLYSIS; JURKAT CELLS; LIPASE; MICE; MOLECULAR STRUCTURE; PEPTIDE HYDROLASES; PHOSPHORIC ACIDS; STAVUDINE;

BACTERIA (MICROORGANISMS);

EID: 33747159640     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.05.037     Document Type: Article

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