Phytanic acid: Production from phytol, its breakdown and role in human disease

Cellular and Molecular Life Sciences

Volumn 63, Issue 15, 2006, Pages 1752-1765

  Van Den Brink, D M ^a,b   Wanders, R J A ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

oxidation; Peroxisome; Peroxisome biogenesis disorder; Phytanic acid; Phytol; Refsum disease; Rhizomelic chondrodysplasia punctata

Indexed keywords

ACETYL COENZYME A ACETYLTRANSFERASE; ALDEHYDE DEHYDROGENASE; CALCIUM; CELL NUCLEUS RECEPTOR; ETHER PHOSPHOLIPID; FATTY ALDEHYDE DEHYDROGENASE; GLYOXYLIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; PHYTANIC ACID; PHYTOL; PLASMALOGEN; PRISTANAL; PRISTANIC ACID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ANOSMIA; CELLULAR DISTRIBUTION; CEREBELLAR ATAXIA; CHONDRODYSPLASIA PUNCTATA; CHROMOSOME 6Q; CLINICAL FEATURE; DECARBOXYLATION; DEHYDROGENATION; DETOXIFICATION; DIETARY INTAKE; DISORDERS OF PEROXISOMAL FUNCTIONS; FATTY ACID OXIDATION; GENE; GENE MUTATION; GENETIC HETEROGENEITY; HEARING IMPAIRMENT; HEART ARRHYTHMIA; HUMAN; HYDROXYLATION; ICHTHYOSIS; OXIDATION; PAHX GENE; PERIPHERAL NEUROPATHY; PEROXISOME; PEX7 GENE; PHOSPHOLIPID SYNTHESIS; REFSUM DISEASE; RETINITIS PIGMENTOSA; REVIEW; SYSTEMATIC REVIEW; TOXICITY;

ALDEHYDE OXIDOREDUCTASES; CHONDRODYSPLASIA PUNCTATA, RHIZOMELIC; HUMANS; OXIDATION-REDUCTION; PEROXISOMAL DISORDERS; PEROXISOMES; PHYTANIC ACID; PHYTOL; PROTEIN TRANSPORT; REFSUM DISEASE;

EID: 33747106226     PISSN: 1420682X     EISSN: 15691632     Source Type: Journal    
DOI: 10.1007/s00018-005-5463-y     Document Type: Review

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