Retraction of synapses and dendritic spines induced by off-target effects of RNA interference

Journal of Neuroscience

Volumn 26, Issue 30, 2006, Pages 7820-7825

  Alvarez, Veronica A ^a   Ridenour, Dennis A ^a   Sabatini, Bernardo L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Dendritic spine; Interferon response; Off target effects; RNA interference; Short hairpin RNA; Synaptic transmission

Indexed keywords

DOUBLE STRANDED RNA; LUCIFERASE; SHORT HAIRPIN RNA; NERVE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DENDRITIC SPINE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; GENE SEQUENCE; GENE SILENCING; GENETIC ANALYSIS; HUMAN; INNER CELL MASS; MORPHOLOGY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; PYRAMIDAL NERVE CELL; RAT; RNA INTERFERENCE; SYNAPSE; SYNAPTIC TRANSMISSION; ADAPTATION; ANIMAL; CELL CULTURE; DENDRITE; GENETICS; HIPPOCAMPUS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELLS, CULTURED; DENDRITES; HIPPOCAMPUS; NERVE TISSUE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA INTERFERENCE; SYNAPSES;

EID: 33747063840     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1957-06.2006     Document Type: Article

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