A glutamic acid 3-methyltransferase encoded by an accessory gene locus important for daptomycin biosynthesis in Streptomyces roseosporus

Molecular Microbiology

Volumn 61, Issue 5, 2006, Pages 1294-1307

  Nguyen, Kien T ^a   Kau, David ^a,b   Gu, Jian Qiao ^a   Brian, Paul ^a   Wrigley, Stephen K ^a,c   Baltz, Richard H ^a   Miao, Vivian ^a,d  

^a CUBIST PHARMACEUTICALS INC   (United States)

^b LONZA AG   (Switzerland)

^c Recombinogen Ltd   (United Kingdom)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLGLUTAMIC ACID; AMINO ACID DERIVATIVE; CALCIUM; CYCLOPEPTIDE; DAPTOMYCIN; GENE PRODUCT; GLUTAMIC ACID; GLUTAMIC ACID 3 METHYLTRANSFERASE; LIPOPEPTIDE; METHYLTRANSFERASE; PEPTIDE SYNTHASE; POLYPEPTIDE ANTIBIOTIC AGENT; THIOL ESTER HYDROLASE; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DPTG GENE; DPTH GENE; DPTI GENE; DPTJ GENE; DPTL GENE; GENE DELETION; GENE LOCUS; GENETIC ANALYSIS; GENETIC COMPLEMENTATION; GENETIC CONSERVATION; GLMT GENE; MUTANT; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; STAPHYLOCOCCUS AUREUS; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES FRADIAE; STREPTOMYCES ROSEOSPORUS; SYNTHESIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DAPTOMYCIN; GLUTAMIC ACID; MASS SPECTROMETRY; METHYLTRANSFERASES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOMYCES;

STAPHYLOCOCCUS AUREUS; STREPTOMYCES COELICOLOR; STREPTOMYCES FILAMENTOSUS; STREPTOMYCES FRADIAE;

EID: 33747056235     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2006.05305.x     Document Type: Article

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