Daptomycin

Nature Reviews Drug Discovery

Volumn 2, Issue 12, 2003, Pages 943-944

  Raja, Aarti ^b   LaBonte, Jason ^b   Lebbos, John ^b   Kirkpatrick, Peter ^a  

^a Nature Reviews Drug Discovery   (United States)

^b Decision Resources Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEPHALOSPORIN DERIVATIVE; DALBAVANCIN; DALFOPRISTIN PLUS QUINUPRISTIN; DAPTOMYCIN; LINEZOLID; MACROLIDE; METICILLIN; ORITAVANCIN; OXAZOLIDINONE DERIVATIVE; PENICILLIN DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; STREPTOGRAMIN DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN; VICURON;

ANTIBIOTIC RESISTANCE; BACTERIAL ENDOCARDITIS; BACTERIAL INFECTION; BACTERICIDAL ACTIVITY; CLINICAL TRIAL; DRUG APPROVAL; DRUG CLASSIFICATION; DRUG EFFICACY; DRUG MARKETING; DRUG MECHANISM; DRUG POTENCY; DRUG SAFETY; DRUG STRUCTURE; DRUG TOLERABILITY; FOOD AND DRUG ADMINISTRATION; GRAM POSITIVE BACTERIUM; HUMAN; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; NOTE; PRIORITY JOURNAL; SIDE EFFECT; SKIN INFECTION; STREPTOMYCES;

EID: 0346958244     PISSN: 14741776     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrd1258     Document Type: Note

References (7)

1. Coates, A. et al. The future challenges facing the development of new antimicrobial drugs. Nature Rev. Drug Discov. 1, 895-910 (2002).
2. Walsh, C. Where will new antibiotics come from? Nature Rev. Microbiol. 1, 65-69 (2003).
3. Lowy, F. D. Antimicrobial resistance: the example of Staphylococcus aureus. J. Clin. Invest 111, 1265-1273 (2003).
4. Tally, F. P. & DeBruin, M. F. Development of daptomycin for Gram-positive infections. J. Antimicrob. Chemother. 46, 523-526 (2000).
5. FDA Drug Approvals List [online] (cited 29 October 2003). (2003).
6. Debono, M. et al, Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032). J. Antibiot. (Tokyo) 41, 1093-1105 (1988).
7. Fuchs, P. C. et al. In vitro bactericidal acitivity of daptomycin against staphylococci. J. Antimicrob. Chemother. 49, 467-470 (2002).