Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain

Journal of Biological Chemistry

Volumn 279, Issue 46, 2004, Pages 48214-48233

  Scott, Catherine ^a   Higgins, Maureen E ^a   Davies, Joanna P ^a   Ioannou, Yiannis A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL MEMBRANES; DISEASE CONTROL; DISEASES; LIPIDS; PROTEINS;

CHIMERIC FUSION; ENDOSOMES; STEROL; TRANSMEMBRANE PROTEIN;

MEMBRANES;

LEUCINE; MEMBRANE PROTEIN; MUTANT PROTEIN; PROTEIN NIEMANN PICK TYPE C1; STEROL; UNCLASSIFIED DRUG;

ARTICLE; CELLULAR DISTRIBUTION; CYTOPLASM; ENDOSOME; GOLGI COMPLEX; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; MUTATION; NIEMANN PICK DISEASE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, CD; BIOLOGICAL MARKERS; CARRIER PROTEINS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CHOLESTEROL; COS CELLS; ENDOSOMES; FIBROBLASTS; HUMANS; LEUCINE; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 9144244897     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M406090200     Document Type: Article

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