-
1
-
-
2942715265
-
Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts
-
Aizaki, H., Lee, K.J., Sung, V.M., Ishiko H., and Lai, M.M. (2004). Characterization of the hepatitis C virus RNA replication complex associated with lipid rafts. Virology 324, 450-461.
-
(2004)
Virology
, vol.324
, pp. 450-461
-
-
Aizaki, H.1
Lee, K.J.2
Sung, V.M.3
Ishiko, H.4
Lai, M.M.5
-
2
-
-
0347915584
-
Enzyme activity - It's all about image
-
Baruch, A., Jeffery, D.A., and Bogyo, M. (2004). Enzyme activity - it's all about image. Trends Cell Biol. 14, 29-35.
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 29-35
-
-
Baruch, A.1
Jeffery, D.A.2
Bogyo, M.3
-
3
-
-
0842308319
-
Transmembrane proteases in cell growth and invasion: New contributors to angiogenesis?
-
Bauvois, B. (2004). Transmembrane proteases in cell growth and invasion: new contributors to angiogenesis? Oncogene 23, 317-329.
-
(2004)
Oncogene
, vol.23
, pp. 317-329
-
-
Bauvois, B.1
-
4
-
-
0036100578
-
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex
-
Egger, D., Wolk, B., Gosert, R., Bianchi, L., Blum, H.E., Moradpour, D., and Bienz, K. (2002). Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex. J. Virol. 76, 5974-5984.
-
(2002)
J. Virol.
, vol.76
, pp. 5974-5984
-
-
Egger, D.1
Wolk, B.2
Gosert, R.3
Bianchi, L.4
Blum, H.E.5
Moradpour, D.6
Bienz, K.7
-
5
-
-
10944243117
-
Proteolysis as a regulatory mechanism
-
Ehrmann, M. and Clausen, T. (2004). Proteolysis as a regulatory mechanism. Annu. Rev. Genet. 38, 709-724.
-
(2004)
Annu. Rev. Genet.
, vol.38
, pp. 709-724
-
-
Ehrmann, M.1
Clausen, T.2
-
6
-
-
0038415985
-
Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication
-
Elazar, M., Cheong, K.H., Liu, P., Greenberg, H.B., Rice, C.M., and Glenn, J.S. (2003). Amphipathic helix-dependent localization of NS5A mediates hepatitis C virus RNA replication. J. Virol. 77, 6055-6061.
-
(2003)
J. Virol.
, vol.77
, pp. 6055-6061
-
-
Elazar, M.1
Cheong, K.H.2
Liu, P.3
Greenberg, H.B.4
Rice, C.M.5
Glenn, J.S.6
-
7
-
-
20144379712
-
Molecular determinants of TRIP proteolysis mediated by the hepatitis C virus NS3/4A protease
-
Ferreon, J.C., Ferreon, A.C., Li, K., and Lemon, S.M. (2005). Molecular determinants of TRIP proteolysis mediated by the hepatitis C virus NS3/4A protease. J. Biol. Chem. 280, 20483-20492.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20483-20492
-
-
Ferreon, J.C.1
Ferreon, A.C.2
Li, K.3
Lemon, S.M.4
-
8
-
-
0037418440
-
Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis
-
Golde, T.E. and Eckman, C.B. (2003). Physiologic and pathologic events mediated by intramembranous and juxtamembranous proteolysis. Sci. STKE 172, RE4.
-
(2003)
Sci. STKE
, vol.172
-
-
Golde, T.E.1
Eckman, C.B.2
-
9
-
-
24344442462
-
The therapeutic potential of NS3 protease inhibitors in HCV infection
-
Goudreau, N. and Llinas-Brunet, M. (2005). The therapeutic potential of NS3 protease inhibitors in HCV infection. Expert. Opin. Invest. Drugs 14, 1129-1144.
-
(2005)
Expert. Opin. Invest. Drugs
, vol.14
, pp. 1129-1144
-
-
Goudreau, N.1
Llinas-Brunet, M.2
-
10
-
-
17844375654
-
Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells
-
Hamill, P. and Jean, F. (2005). Enzymatic characterization of membrane-associated hepatitis C virus NS3-4A heterocomplex serine protease activity expressed in human cells. Biochemistry 44, 6586-6596.
-
(2005)
Biochemistry
, vol.44
, pp. 6586-6596
-
-
Hamill, P.1
Jean, F.2
-
11
-
-
0029056450
-
An internally quenched fluorogenic substrate of prohormone convertase 1 and furin leads to a potent prohormone convertase inhibitor
-
Jean, F., Basak, A., DiMaio, J., Seidah, N.G., and Lazure, C. (1995a). An internally quenched fluorogenic substrate of prohormone convertase 1 and furin leads to a potent prohormone convertase inhibitor. Biochem. J. 307, 689-695.
-
(1995)
Biochem. J.
, vol.307
, pp. 689-695
-
-
Jean, F.1
Basak, A.2
DiMaio, J.3
Seidah, N.G.4
Lazure, C.5
-
12
-
-
0029135124
-
Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor
-
Jean, F., Boudreault, A., Basak, A., Seidah, N.G., and Lazure, C. (1995b). Fluorescent peptidyl substrates as an aid in studying the substrate specificity of human prohormone convertase PC1 and human furin and designing a potent irreversible inhibitor. J. Biol. Chem. 270, 19225-19231.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 19225-19231
-
-
Jean, F.1
Boudreault, A.2
Basak, A.3
Seidah, N.G.4
Lazure, C.5
-
13
-
-
0033777736
-
Development and application of a GFP-FRET intracellular caspase assay for drug screening
-
Jones, J., Heim, R., Hare, E., Stack, J., and Pollok, B.A. (2000). Development and application of a GFP-FRET intracellular caspase assay for drug screening. J. Biomol. Screen. 5, 307-318.
-
(2000)
J. Biomol. Screen.
, vol.5
, pp. 307-318
-
-
Jones, J.1
Heim, R.2
Hare, E.3
Stack, J.4
Pollok, B.A.5
-
14
-
-
0034663698
-
In vivo determination of substrate specificity of hepatitis C virus NS3 protease: Genetic assay for site-specific proteolysis
-
Kim, S.Y., Park, K.W., Lee, Y.J., Back, S.H., Goo, J.H., Park, O.K., Jang, S.K., and Park, W.J. (2000). In vivo determination of substrate specificity of hepatitis C virus NS3 protease: genetic assay for site-specific proteolysis. Anal. Biochem. 284, 42-48.
-
(2000)
Anal. Biochem.
, vol.284
, pp. 42-48
-
-
Kim, S.Y.1
Park, K.W.2
Lee, Y.J.3
Back, S.H.4
Goo, J.H.5
Park, O.K.6
Jang, S.K.7
Park, W.J.8
-
15
-
-
0344201903
-
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
-
Lamarre, D., Anderson, P.C., Bailey, M., Beulieu, P., Bolger, G., Bonneau, P., Bos, M., Cameron, D.R., Cartier, M., Cordingley, M.G., et al. (2003). An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus. Nature 426, 186-189.
-
(2003)
Nature
, vol.426
, pp. 186-189
-
-
Lamarre, D.1
Anderson, P.C.2
Bailey, M.3
Beulieu, P.4
Bolger, G.5
Bonneau, P.6
Bos, M.7
Cameron, D.R.8
Cartier, M.9
Cordingley, M.G.10
-
16
-
-
14544280209
-
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
-
USA
-
Li, K., Foy, E., Ferreon, J.C., Nakamura, M., Ferreon, A.C., Ikeda, M., Ray, S.C., Gale, M. Jr., and Lemon, S.M. (2005a). Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc. Natl. Acad. Sci. USA 102, 2992-2997.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 2992-2997
-
-
Li, K.1
Foy, E.2
Ferreon, J.C.3
Nakamura, M.4
Ferreon, A.C.5
Ikeda, M.6
Ray, S.C.7
Gale Jr., M.8
Lemon, S.M.9
-
17
-
-
29144462494
-
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
USA
-
Li, X.D., Sun, L., Seth, R.B., Pineda, G., and Chen, Z.J. (2005b). Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc. Natl. Acad. Sci. USA 102, 17717-17722.
-
(2005)
Proc. Natl. Acad. Sci.
, vol.102
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
18
-
-
0032867477
-
Fluorescent proteins from nonbioluminescent Anthozoa species
-
Matz, M.V., Fradkov, A.F., Labas, Y.A., Savitsky, A.P., Zaraisky, A.G., Markelov, M.L., and Lukyanov, S.A. (1999). Fluorescent proteins from nonbioluminescent Anthozoa species. Nat. Biotechnol. 17, 969-973.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 969-973
-
-
Matz, M.V.1
Fradkov, A.F.2
Labas, Y.A.3
Savitsky, A.P.4
Zaraisky, A.G.5
Markelov, M.L.6
Lukyanov, S.A.7
-
19
-
-
3142764760
-
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes
-
Moradpour, D., Evans, M.J., Gosert, R., Yuan, Z., Blum, H.E., Goff, S.P., Lindenbach, B.D., and Rice, C.M. (2004). Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes. J. Virol. 78, 7400-7409.
-
(2004)
J. Virol.
, vol.78
, pp. 7400-7409
-
-
Moradpour, D.1
Evans, M.J.2
Gosert, R.3
Yuan, Z.4
Blum, H.E.5
Goff, S.P.6
Lindenbach, B.D.7
Rice, C.M.8
-
20
-
-
24144438257
-
Function follows form: The structure of the N-terminal domain of HCV NS5A
-
Moradpour, D., Brass, V., and Penin, F. (2005). Function follows form: the structure of the N-terminal domain of HCV NS5A. Hepatology 42, 732-735.
-
(2005)
Hepatology
, vol.42
, pp. 732-735
-
-
Moradpour, D.1
Brass, V.2
Penin, F.3
-
21
-
-
0036346236
-
Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons
-
Mottola, G., Cardinali, G., Ceccacci, A., Trozzi, C., Bartholomew, L., Torrisi, M.R., Pedrazzini, E., Bonatti, S., and Migliaccio, G. (2002). Hepatitis C virus nonstructural proteins are localized in a modified endoplasmic reticulum of cells expressing viral subgenomic replicons. Virology 293, 31-43.
-
(2002)
Virology
, vol.293
, pp. 31-43
-
-
Mottola, G.1
Cardinali, G.2
Ceccacci, A.3
Trozzi, C.4
Bartholomew, L.5
Torrisi, M.R.6
Pedrazzini, E.7
Bonatti, S.8
Migliaccio, G.9
-
22
-
-
0037688169
-
Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer
-
Netzel-Arnett, S., Hooper, J.D., Szabo, R., Madison, E.L., Quigley, J.P., Bugge, T.H., and Antalis, T.M. (2003). Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer. Cancer Metastasis Rev. 22, 237-258.
-
(2003)
Cancer Metastasis Rev.
, vol.22
, pp. 237-258
-
-
Netzel-Arnett, S.1
Hooper, J.D.2
Szabo, R.3
Madison, E.L.4
Quigley, J.P.5
Bugge, T.H.6
Antalis, T.M.7
-
23
-
-
1642276021
-
Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: Induced fit as a mechanism for narrow specificity
-
Richer, M.J., Juliano, L., Hashimoto, C., and Jean, F. (2004). Serpin mechanism of hepatitis C virus nonstructural 3 (NS3) protease inhibition: induced fit as a mechanism for narrow specificity. J. Biol. Chem. 279, 10222-10227.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10222-10227
-
-
Richer, M.J.1
Juliano, L.2
Hashimoto, C.3
Jean, F.4
-
24
-
-
5644258600
-
Viral RNA replication in association with cellular membranes
-
Salonen, A., Ahola, T., and Kaariainen, L. (2005). Viral RNA replication in association with cellular membranes. Curr. Top. Microbiol. Immunol. 285, 139-173.
-
(2005)
Curr. Top. Microbiol. Immunol.
, vol.285
, pp. 139-173
-
-
Salonen, A.1
Ahola, T.2
Kaariainen, L.3
-
25
-
-
0014211618
-
On the size of the active site in proteases. I. Papain
-
Schechter, I. and Berger, A. (1967). On the size of the active site in proteases. I. Papain. Biochem. Biophys. Res. Commun. 27, 157-162.
-
(1967)
Biochem. Biophys. Res. Commun.
, vol.27
, pp. 157-162
-
-
Schechter, I.1
Berger, A.2
-
26
-
-
0035135797
-
Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis
-
Tawa, P., Tam, J., Cassady, R., Nicholson, D.W., and Xanthoudakis, S. (2001). Quantitative analysis of fluorescent caspase substrate cleavage in intact cells and identification of novel inhibitors of apoptosis. Cell Death Differ. 8, 30-37.
-
(2001)
Cell Death Differ.
, vol.8
, pp. 30-37
-
-
Tawa, P.1
Tam, J.2
Cassady, R.3
Nicholson, D.W.4
Xanthoudakis, S.5
-
27
-
-
4143084775
-
Intramembrane proteolysis: Theme and variations
-
Wolfe, M.S. and Kopan, R. (2004). Intramembrane proteolysis: theme and variations. Science 305, 1119-1123.
-
(2004)
Science
, vol.305
, pp. 1119-1123
-
-
Wolfe, M.S.1
Kopan, R.2
-
28
-
-
0242456017
-
Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A expressed in tetracycline-regulated cell lines
-
Wolk, B., Sansonno, D., Krausslich, H.G., Dammacco, F., Rice, C.M., Blum, H.E., and Moradpour, D. (2000). Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A expressed in tetracycline-regulated cell lines. J. Virol. 74, 2293-2304.
-
(2000)
J. Virol.
, vol.74
, pp. 2293-2304
-
-
Wolk, B.1
Sansonno, D.2
Krausslich, H.G.3
Dammacco, F.4
Rice, C.M.5
Blum, H.E.6
Moradpour, D.7
-
29
-
-
0030844455
-
Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides
-
Zhang, R., Durkin, J., Windsor, W.T., McNemar, C., Ramanathan, L., and Le, H.V. (1997). Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides. J. Virol. 71, 6208-6213.
-
(1997)
J. Virol.
, vol.71
, pp. 6208-6213
-
-
Zhang, R.1
Durkin, J.2
Windsor, W.T.3
McNemar, C.4
Ramanathan, L.5
Le, H.V.6
|