Plasma and dietary carotenoid, retinol and tocopherol levels and the risk of gastric adenocarcinomas in the European prospective investigation into cancer and nutrition

British Journal of Cancer

Volumn 95, Issue 3, 2006, Pages 406-415

  Jenab, M ^a   Riboli, E ^a   Ferrari, P ^a   Friesen, M ^a   Sabate, J ^a,b   Norat, T ^a   Slimani, N ^a   Tjonneland A ^c   Olsen, A ^c   Overvad, K ^d   Boutron Ruault, M C ^e   Clavel Chapelon, F ^e   Boeing, H ^f   Schulz, M ^f   Linseisen, J ^g   Nagel, G ^g   Trichopoulou, A ^h   Naska, A ^h   Oikonomou, E ^h   Berrino, F ⁱ   Panico, S ^j   Palli, D ^k   Sacerdote, C ^l   Tumino, R ^m   Peeters, P H ⁿ   Numans, M E ⁿ   Bueno De Mesquita, H B ^o   Buchner F L ^o   Lund, E ^p   Pera, G ^q   Chirlaque, M D ^r   Sanchez M J ^s   Arriola, L ^t   Barricarte, A ^u   Quiros J R ^v   Johansson, I ^w   Johansson, A ^w   Berglund, G ^x   Bingham, S ^y   Khaw, K T ^y   Allen, N ^z   Key, T ^z   Carneiro, F ^aa   Save, V ^ab   Del Giudice, G ^ac   Plebani, M ^ad   Kaaks, R ^a   Gonzalez, C A ^q   more..

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b LOMA LINDA UNIVERSITY   (United States)

^c INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^d AALBORG UNIVERSITY HOSPITAL   (Denmark)

^e INSTITUT GUSTAVE ROUSSY   (France)

^f GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^h UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

ⁱ NATIONAL CANCER INSTITUTE   (Italy)

^j UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^k CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^l UNIVERSITY OF TURIN   (Italy)

^m CIVILE M P AREZZO HOSPITAL   (Italy)

ⁿ UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^o NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^p UNIVERSITY OF TROMSØ   (Norway)

^q BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^r HOSPITAL GENERAL UNIVERSITARIO REINA SOFÍA   (Spain)

^s ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^t Public Health Department of Guipuzkoa   (Spain)

^u INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^v Seccion Informacion Sanitaria   (Spain)

^w UMEÅ UNIVERSITY   (Sweden)

^x KAROLINSKA INSTITUTE   (Sweden)

^y UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^z UNIVERSITY OF OXFORD   (United Kingdom)

^aa University of Porto   (Portugal)

^ab ADDENBROOKE S HOSPITAL   (United Kingdom)

^ac NOVARTIS VACCINES AND DIAGNOSTICS   (Italy)

^ad UNIVERSITY HOSPITAL OF PADOVA   (Italy)

more..

Author keywords

Carotenoids; Diet; EPIC; Gastric cancer; Retinol; Tocopherol

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BETA CRYPTOXANTHIN; CAROTENOID; GAMMA TOCOPHEROL; LIPID; RETINOL; TOCOPHEROL; TRACE ELEMENT;

ADULT; AGED; ARTICLE; BLOOD DONOR; BLOOD LEVEL; BODY MASS; CALORIC INTAKE; CANCER INCIDENCE; CANCER RISK; CAUSE OF DEATH; COHORT ANALYSIS; CONTROLLED STUDY; DIETARY INTAKE; EUROPE; FOLLOW UP; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; NUTRITION; PRIORITY JOURNAL; SMOKING; STOMACH ADENOCARCINOMA; STOMACH CANCER;

ADENOCARCINOMA; ADULT; AGED; CAROTENOIDS; CASE-CONTROL STUDIES; DIET; EUROPE; FOLLOW-UP STUDIES; HUMANS; MIDDLE AGED; NUTRITION PHYSIOLOGY; NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PROSPECTIVE STUDIES; RISK FACTORS; STOMACH NEOPLASMS; TOCOPHEROLS; VITAMIN A;

EID: 33746876654     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603266     Document Type: Article

References (61)

1. Abnet CC, Qiao YL, Dawsey SM, Buckman DW, Yang CS, Blot WJ, Dong ZW, Taylor PR, Mark SD (2003) Prospective study of serum retinol, beta-carotene, beta-cryptoxanthin, and lutein/zeaxanthin and esophageal and gastric cancers in China. Cancer Causes Control 14: 645-655
2. Al Delaimy WK, Ferrari P, Slimani N, Pala V, Johansson I, Nilsson S, Mattisson I, Wirfalt E, Galasso R, Palli D, Vineis P, Tumino R, Dorronsoro M, Pera G, Ocke MC, Bueno-De-Mesquita HB, Overvad K, Chirlaque M, Trichopoulou A, Naska A, Tjonneland A, Olsen A, Lund E, Alsaker EH, Barricarte A, Kesse E, Boutron-Ruault MC, Clavel-Chapelon F, Key TJ, Spencer E, Bingham S, Welch AA, Sanchez-Perez MJ, Nagel G, Linseisen J, Quiros JR, Peeters PH, van Gils CH, Boeing H, van Kappel AL, Steghens JP, Riboli E (2005a) Plasma carotenoids as biomarkers of intake of fruits and vegetables: individual-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Clin Nutr 59: 1387-1396
3. Al Delaimy WK, Slimani N, Ferrari P, Key T, Spencer E, Johansson I, Johansson G, Mattisson I, Wirfalt E, Sieri S, Agudo A, Celentano E, Palli D, Sacerdote C, Tumino R, Dorronsoro M, Ocke MC, Bueno-De-Mesquita HB, Overvad K, Chirlaque MD, Trichopoulou A, Naska A, Tjonneland A, Olsen A, Lund E, Skeie G, Ardanaz E, Kesse E, Boutron-Ruault MC, Clavel-Chapelon F, Bingham S, Welch AA, Martinez-Garcia C, Nagel G, Linseisen J, Quiros JR, Peeters PH, van Gils CH, Boeing H, van Kappel AL, Steghens JP, Riboli E (2005b) Plasma carotenoids as biomarkers of intake of fruits and vegetables: ecological-level correlations in the European Prospective Investigation into Cancer and Nutrition (EPIC). Eur J Clin Nutr 59: 1397-1408
4. Annibale B, Capurso G, Delle FG (2002) Consequences of Helicobacter pylori infection on the absorption of micronutrients. Dig Liver Dis 34(Suppl 2): S72-S77
5. Blot WJ, Li JY, Taylor PR, Guo W, Dawsey SM, Li B (1995) The Linxian trials: mortality rates by vitamin-mineral intervention group. Am J Clin Nutr 62: 1424S-1426S
6. Boeing H, Jedrychowski W, Wahrendorf J, Popiela T, Tobiasz-Adamczyk B, Kulig A (1991) Dietary risk factors in intestinal and diffuse types of stomach cancer: a multicenter case-control study in Poland. Cancer Causes Control 2: 227-233
7. Botterweck AA, Schouten LJ, Volovics A, Dorant E, van Den Brandt PA (2000a) Trends in incidence of adenocarcinoma of the oesophagus and gastric cardia in ten European countries. Int J Epidemiol 29: 645-654
8. Botterweck AA, van Den Brandt PA, Goldbohm RA (2000b) Vitamins, carotenoids, dietary fiber, and the risk of gastric carcinoma: results from a prospective study after 6.3 years of follow-up. Cancer 88: 737-748
9. Buiatti E, Palli D, Bianchi S, Decarli A, Amadori D, Avellini C, Cipriani F, Cocco P, Giacosa A, Lorenzini L, Marubini E, Puntoni R, Saragoni A, Fraumeni Jr JF, Blot WJ (1991) A case-control study of gastric cancer and diet in Italy. III. Risk patterns by histologic type. Int J Cancer 48: 369-374
10. Buiatti E, Palli D, Decarli A, Amadori D, Avellini C, Bianchi S, Bonaguri C, Cipriani F, Cocco P, Giacosa A, Marubini E, Minacci C, Puntoni R, Russo A, Vindigni C, Fraumeni Jr JF, Blot WJ (1990) A case-control study of gastric cancer and diet in Italy: II. Association with nutrients. Int J Cancer 45: 896-901
11. Chajes V, Hulten K, van Kappel AL, Winkvist A, Kaaks R, Hallmans G, Lenner P, Riboli E (1999) Fatty-acid composition in serum phospholipids and risk of breast cancer: an incident case-control study in Sweden. Int J Cancer 83: 585-590
12. Chen H, Tucker KL, Graubard BI, Heineman EF, Markin RS, Potischman NA, Russell RM, Weisenburger DD, Ward MH (2002) Nutrient intakes and adenocarcinoma of the esophagus and distal stomach. Nutr Cancer 42: 33-40
13. Chyou PH, Nomura AM, Hankin JH, Stemmermann GN (1990) A case-cohort study of diet and stomach cancer. Cancer Res 50: 7501-7504
14. Corley DA, Kubo A (2004) Influence of site classification on cancer incidence rates: an analysis of gastric cardia carcinomas. J Natl Cancer Inst 96: 1383-1387
15. Correa P, Fontham ET, Bravo JC, Bravo LE, Ruiz B, Zarama G, Realpe JL, Malcom GT, Li D, Johnson WD, Mera R (2000) Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-Helicobacter pylori therapy. J Natl Cancer Inst 92: 1881-1888
16. Correa P, Malcom G, Schmidt B, Fontham E, Ruiz B, Bravo JC, Bravo LE, Zarama G, Realpe JL (1998) Review article: antioxidant micronutrients and gastric cancer. Aliment Pharmacol Ther 12(Suppl 1): 73-82
17. Correa P, Shiao YH (1994) Phenotypic and genotypic events in gastric carcinogenesis. Cancer Res 54: 1941s-1943s
18. Donaldson MS (2004) Nutrition and cancer: a review of the evidence for an anti-cancer diet. Nutr J 3: 19
19. Eichholzer M, Stahelin HB, Gey KF, Ludin E, Bernasconi F (1996) Prediction of male cancer mortality by plasma levels of interacting vitamins: 17-year follow-up of the prospective Basel study. Int J Cancer 66: 145-150
20. Ekstrom AM, Serafini M, Nyren O, Hansson LE, Ye W, Wolk A (2000) Dietary antioxidant intake and the risk of cardia cancer and noncardia cancer of the intestinal and diffuse types: a population-based case-control study in Sweden. Int J Cancer 87: 133-140
21. Engel LS, Chow WH, Vaughan TL, Gammon MD, Risch HA, Stanford JL, Schoenberg JB, Mayne ST, Dubrow R, Rotterdam H, West AB, Blaser M, Blot WJ, Gail MH, Fraumeni Jr JF (2003) Population attributable risks of esophageal and gastric cancers. J Natl Cancer Inst 95: 1404-1413
22. Garcia-Closas R, Gonzalez CA, Agudo A, Riboli E (1999) Intake of specific carotenoids and flavonoids and the risk of gastric cancer in Spain. Cancer Causes Control 10: 71-75
23. Gonzalez CA, Pera G, Agudo A, Bueno-De-Mesquita HB, Ceroti M, Boeing H, Schulz M, Del Giudice G, Plebani M, Carneiro F, Berrino F, Sacerdote C, Tumino R, Panico S, Berglund G, Siman H, Hallmans G, Stenling R, Martinez C, Dorronsoro M, Barricarte A, Navarro C, Quiros JR, Allen N, Key TJ, Bingham S, Day NE, Linseisen J, Nagel G, Overvad K, Jensen MK, Olsen A, Tjonneland A, Buchner FL, Peeters PH, Numans ME, Clavel-Chapelon F, Boutron-Ruault MC, Roukos D, Trichopoulou A, Psaltopoulou T, Lund E, Casagrande C, Slimani N, Jenab M, Riboli E (2006) Fruit and vegetable intake and the risk of stomach and oesophagus adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC-EURGAST). Int J Cancer 118: 2559-2566
24. Gonzalez CA, Pera G, Agudo A, Palli D, Krogh V, Vineis P, Tumino R, Panico S, Berglund G, Siman H, Nyren O, Agren A, Martinez C, Dorronsoro M, Barricarte A, Tormo MJ, Quiros JR, Allen N, Bingham S, Day N, Miller A, Nagel G, Boeing H, Overvad K, Tjonneland A, Bueno-De-Mesquita HB, Boshuizen HC, Peeters P, Numans M, Clavel-Chapelon F, Helen I, Agapitos E, Lund E, Fahey M, Saracci R, Kaaks R, Riboli E (2003) Smoking and the risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer 107: 629-634
25. Gonzalez CA, Riboli E, Badosa J, Batiste E, Cardona T, Pita S, Sanz JM, Torrent M, Agudo A (1994) Nutritional factors and gastric cancer in Spain. Am J Epidemiol 139: 466-473
26. Hankinson SE, London SJ, Chute CG, Barbieri RL, Jones L, Kaplan LA, Sacks FM, Stampfer MJ (1989) Effect of transport conditions on the stability of biochemical markers in blood. Clin Chem 35: 2313-2316
27. Hansson LE, Engstrand L, Nyren O, Evans Jr DJ, Lindgren A, Bergstrom R, Andersson B, Athlin L, Bendtsen O, Tracz P (1993a) Helicobacter pylori infection: independent risk indicator of gastric adenocarcinoma. Gastroenterology 105: 1098-1103
28. Hansson LE, Nyren O, Bergstrom R, Wolk A, Lindgren A, Baron J, Adami HO (1994) Nutrients and gastric cancer risk. A population-based case-control study in Sweden. Int J Cancer 57: 638-644
29. Hansson LE, Sparen P, Nyren O (1993b) Increasing incidence of both major histological types of esophageal carcinomas among men in Sweden. Int J Cancer 54: 402-407
30. Harrison LE, Zhang ZF, Karpeh MS, Sun M, Kurtz RC (1997) The role of dietary factors in the intestinal and diffuse histologic subtypes of gastric adenocarcinoma: a case-control study in the US. Cancer 80: 1021-1028
31. Hennekens CH, Buring JE, Manson JE, Stampfer M, Rosner B, Cook NR, Belanger C, LaMotte F, Gaziano JM, Ridker PM, Willett W, Peto R (1996) Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 334: 1145-1149
32. Kelley JR, Duggan JM (2003) Gastric cancer epidemiology and risk factors. J Clin Epidemiol 56: 1-9
33. Key T, Oakes S, Davey G, Moore J, Edmond LM, McLoone UJ, Thurnham DI (1996) Stability of vitamins A, C, and E, carotenoids, lipids, and testosterone in whole blood stored at 4 degrees C for 6 and 24 h before separation of serum and plasma. Cancer Epidemiol Biomarkers Prev 5: 811-814
34. Lauren PA, Nevalainen TJ (1993) Epidemiology of intestinal and diffuse types of gastric carcinoma. A time-trend study in Finland with comparison between studies from high- and low-risk areas. Cancer 71: 2926-2933
35. Liu RH (2004) Potential synergy of phytochemicals in cancer prevention: mechanism of action. J Nutr 134: 3479S-3485S
36. Nomura AM, Stemmermann GN, Chyou PH (1995) Gastric cancer among the Japanese in Hawaii. Jpn J Cancer Res 86: 916-923
37. Nouraie M, Pietinen P, Kamangar F, Dawsey SM, Abnet CC, Albanes D, Virtamo J, Taylor PR (2005) Fruits, vegetables, and antioxidants and risk of gastric cancer among male smokers. Cancer Epidemiol Biomarkers Prev 14: 2087-2092
38. Ocke MC, Kromhout D, Menotti A, Aravanis C, Blackburn H, Buzina R, Fidanza F, Jansen A, Nedeljkovic S, Nissienen A, Pekkarinen M, Toshima H (1995) Average intake of anti-oxidant (pro)vitamins and subsequent cancer mortality in the 16 cohorts of the Seven Countries Study. Int J Cancer 61: 480-484
39. Palli D, Masala G, Del Giudice G, Plebani M, Basso D, Berti D, Numans ME, Ceroti M, Peeters PHM, Bueno de Mesquita HB, Clavel-Chapelon F, Krogh V, Saieva C, Vineis P, Panico S, Tumino R, Siman H, Berglund G, Hallmans G, Martinez C, Quiros JR, Navarro C, Key T, Bingham S, Boeing H, Linseisen J, Overvad K, Tjonneland A, Trichoupoulou A, Pera G, Nesi G, Carneiro F, Riboli E, Gonzalez CA (2006) CagA+Helicobacter pylori infection, pepsinogen levels and gastric cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPICEUR-GAST). Gastroenterology (in review)
40. Parsonnet J, Friedman GD, Vandersteen DP, Chang Y, Vogelman JH, Orentreich N, Sibley RK (1991) Helicobacter pylori infection and the risk of gastric carcinoma. N Engl J Med 325: 1127-1131
41. Riboli E, Hunt KJ, Slimani N, Ferrari P, Norat T, Fahey M, Charrondiere UR, Hemon B, Casagrande C, Vignat J, Overvad K, Tjonneland A, Clavel-Chapelon F, Thiebaut A, Wahrendorf J, Boeing H, Trichopoulos D, Trichopoulou A, Vineis P, Palli D, Bueno-De-Mesquita HB, Peeters PH, Lund E, Engeset D, Gonzalez CA, Barricarte A, Berglund G, Hallmans G, Day NE, Key TJ, Kaaks R, Saracci R (2002) European Prospective Investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr 5: 1113-1124
42. Riboli E, Kaaks R (1997) The EPIC Project: rationale and study design. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26(Suppl 1): S6-S14
43. Riboli E, Norat T (2003) Epidemiologic evidence of the protective effect of fruit and vegetables on cancer risk. Am J Clin Nutr 78: 559S-569S
44. Rothman KJ, Greenland S (eds) (1998) Introduction to stratified analysis. In Modern Epidemiology, 2nd edn, pp 53-79. Philadelphia, USA: Lippincott-Raven
45. Sporn MB, Roberts AB (1983) Role of retinoids in differentiation and carcinogenesis. Cancer Res 43: 3034-3040
46. Stahelin HB, Gey KF, Eichholzer M, Ludin E, Bernasconi F, Thurneysen J, Brubacher G (1991) Plasma antioxidant vitamins and subsequent cancer mortality in the 12-year follow-up of the prospective Basel Study. Am J Epidemiol 133: 766-775
47. Steghens JP, van Kappel AL, Riboli E, Collombel C (1997) Simultaneous measurement of seven carotenoids, retinol and alpha-tocopherol in serum by high-performance liquid chromatography. J Chromatogr B 694: 71-81
48. Taylor PR, Qiao YL, Abnet CC, Dawsey SM, Yang CS, Gunter EW, Wang W, Blot WJ, Dong ZW, Mark SD (2003) Prospective study of serum vitamin E levels and esophageal and gastric cancers. J Natl Cancer Inst 95: 1414-1416
49. Touvier M, Kesse E, Clavel-Chapelon F, Boutron-Ruault MC (2005) Dual Association of beta-carotene with risk of tobacco-related cancers in a cohort of French women. J Natl Cancer Inst 97: 1338-1344
50. Tsubono Y, Tsugane S, Gey KF (1999) Plasma antioxidant vitamins and carotenoids in five Japanese populations with varied mortality from gastric cancer. Nutr Cancer 34: 56-61
51. van Poppel G, van den Berg H (1997) Vitamins and cancer. Cancer Lett 114: 195-202
52. Varis K, Taylor PR, Sipponen P, Samloff IM, Heinonen OP, Albanes D, Harkonen M, Huttunen JK, Laxen F, Virtamo J (1998) Gastric cancer and premalignant lesions in atrophic gastritis: a controlled trial on the effect of supplementation with alpha-tocopherol and beta-carotene. The Helsinki Gastritis Study Group. Scand J Gastroenterol 33: 294-300
53. Willett W (1998) Nutritional Epidemiology 3 2nd edn. New York, NY: Oxford University Press
54. Willett WC, Polk BF, Underwood BA, Stampfer MJ, Pressel S, Rosner B, Taylor JO, Schneider K, Hames CG (1984) Relation of serum vitamins A and E and carotenoids to the risk of cancer. N Engl J Med 310: 430-434
55. Willett WC, Stampfer MJ, Underwood BA, Speizer FE, Rosner B, Hennekens CH (1983) Validation of a dietary questionnaire with plasma carotenoid and alpha-tocopherol levels. Am J Clin Nutr 38: 631-639
56. Woodward M, Tunstall-Pedoe H, McColl K (2001) Helicobacter pylori infection reduces systemic availability of dietary vitamin C. Eur J Gastroenterol Hepatol 13: 233-237
57. World Cancer Research Fund (1997) Food Research and the Prevention of Cancer: A Global Perspective. Washington, DC: American Institute for Cancer Research
58. You WC, Zhang L, Gail MH, Chang YS, Liu WD, Ma JL, Li JY, Jin ML, Hu YR, Yang CS, Blaser MJ, Correa P, Blot WJ, Fraumeni Jr JF, Xu GW (2000) Gastric dysplasia and gastric cancer: Helicobacter pylori, serum vitamin C, and other risk factors. J Natl Cancer Inst 92: 1607-1612
59. Yuan JM, Ross RK, Gao YT, Qu YH, Chu XD, Yu MC (2004) Prediagnostic levels of serum micronutrients in relation to risk of gastric cancer in Shanghai, China. Cancer Epidemiol Biomarkers Prev 13: 1772-1780
60. Zhang ZW, Patchett SE, Perrett D, Domizio P, Farthing MJ (2000) Gastric alpha-tocopherol and beta-carotene concentrations in association with Helicobacter pylori infection. Eur J Gastroenterol Hepatol 12: 497-503
61. Zheng W, Sellers TA, Doyle TJ, Kushi LH, Potter JD, Folsom AR (1995) Retinol, antioxidant vitamins, and cancers of the upper digestive tract in a prospective cohort study of postmenopausal women. Am J Epidemiol 142: 955-960