An outer membrane enzyme encoded by Salmonella typhimurium lpxR that removes the 3′-acyloxyacyl moiety of lipid A

Journal of Biological Chemistry

Volumn 281, Issue 31, 2006, Pages 21974-21987

  Reynolds, C Michael ^a   Ribeiro, Anthony A ^a   McGrath, Sara C ^b   Cotter, Robert J ^b   Raetz, Christian R H ^a,d   Trent, M Stephen ^c  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c East Tennessee State University   (United States)

^d DUKE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; CATIONIC POLYMERIZATION; ENZYMES; ESCHERICHIA COLI; GENES; LIPIDS; PATHOLOGY; POLYSACCHARIDES;

DEACYLASE ACTIVITY; ENVIRONMENTAL STIMULI; GENE ENCODING; YERSINIA ENTEROCOLITICA;

BACTERIA;

3 ACYLOXYACYL; BACTERIAL PROTEIN; HYDROLASE; LIPID A; MEMBRANE ENZYME; PROTEIN IPXR; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; DEACYLATION; DNA LIBRARY; ENZYME ACTIVITY; ESCHERICHIA COLI; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STRUCTURE; SALMONELLA TYPHIMURIUM; THERMOSTABILITY;

BACTERIAL PROTEINS; CARBOXYLIC ESTER HYDROLASES; GENE LIBRARY; LIPID A; MASS SPECTROMETRY; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN SORTING SIGNALS; SALMONELLA TYPHIMURIUM;

ANIMALIA; ESCHERICHIA COLI K12; HELICOBACTER PYLORI; SALMONELLA; SALMONELLA TYPHIMURIUM; VIBRIO CHOLERAE; YERSINIA ENTEROCOLITICA;

EID: 33746850568     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603527200     Document Type: Article

References (89)

1. Jones, B. D., and Falkow, S. (1996) Annu. Rev. Immunol. 14, 533-561
2. Scherer, C. A., and Miller, S. I. (2001) in Principles of Bacterial Pathogenesis (Groisman, E. A., ed) pp. 229-243, Academic Press, Inc., San Diego, CA
3. Garcia-Del Portillo, F. (1999) Trends Microbiol. 7, 467-469
4. Lindgren, S. W., Stojiljkovic, I., and Heffron, F. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 4197-4201
5. Monack, D. M., Raupach, B., Hromockyj, A. E., and Falkow, S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 9833-9838
6. Richter-Dahlfors, A., Buchan, A. M. J., and Finlay, B. B. (1997) J. Exp. Med. 186, 569-580
7. Beutler, B., and Cerami, A. (1988) Annu. Rev. Biochem. 57, 505-518
8. Dinarello, C. A. (1991) Blood 77, 1627-1652
9. Raetz, C. R. H. (1996) in Escherichia coli and Salmonella: Cellular and Molecular Biology (Neidhardt, F. C., ed) 2nd Ed., pp. 1035-1063, American Society for Microbiology, Washington, D. C.
10. Rietschel, E. T., Kirikae, T., Schade, F. U., Mamat, U., Schmidt, G., Loppnow, H., Ulmer, A. J., Zähringer, U., Seydel, U., Di Padova, F., Schreier, M., and Brade, H. (1994) FASEB J. 8, 217-225
11. Aderem, A., and Ulevitch, R. J. (2000) Nature 406, 782-787
12. Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K., and Akira, S. (1999) J. Immunol. 162, 3749-3752
13. Poltorak, A., He, X., Smirnova, I., Liu, M. Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., Freudenberg, M., Ricciardi-Castagnoli, P., Layton, B., and Beutler, B. (1998) Science 282, 2085-2088
14. Raetz, C. R. H., and Dowhan, W. (1990) J. Biol. Chem. 265, 1235-1238
15. Raetz, C. R. H., and Whitfield, C. (2002) Annu. Rev. Biochem. 71, 635-700
16. Loppnow, H., Brade, H., Dürrbaum, I., Dinarello, C. A., Kusumoto, S., Rietschel, E. T., and Flad, H. D. (1989) J. Immunol. 142, 3229-3238
17. Steeghs, L., Berns, M., ten Hove, J., de Jong, A., Roholl, P., van Alphen, L., Tommassen, J., and van der Ley, P. (2002) Cell. Microbiol. 4, 599-611
18. Trent, M. S., Ribeiro, A. A., Lin, S., Cotter, R. J., and Raetz, C. R. H. (2001) J. Biol. Chem. 276, 43122-43131
19. Lee, H., Hsu, F. F., Turk, J., and Groisman, E. A. (2004) J. Bacteriol. 186, 4124-4133
20. Trent, M. S., and Raetz, C. R. H. (2002) J. Endotoxin Res. 8, 158
21. Baker, S. J., Gunn, J. S., and Morona, R. (1999) Microbiology 145, 367-378
22. Gunn, J. S., Ryan, S. S., Van Velkinburgh, J. C., Ernst, R. K., and Miller, S. I. (2000) Infect. Immun. 68, 6139-6146
23. Helander, I. M., Kato, Y., Kilpelainen, I., Kostiainen, R., Lindner, B., Nummila, K., Sugiyama, T., and Yokochi, T. (1996) Eur. J. Biochem. 237, 272-278
24. Vaara, M., Vaara, T., Jensen, M., Helander, I., Nurminen, M., Rietschel, E. T., and Makela, P. H. (1981) FEBS Lett. 129, 145-149
25. Gibbons, H. S., Lin, S., Cotter, R. J., and Raetz, C. R. H. (2000) J. Biol. Chem. 275, 32940-32949
26. Bishop, R. E., Gibbons, H. S., Guina, T., Trent, M. S., Miller, S. I., and Raetz, C. R. H. (2000) EMBO J. 19, 5071-5080
27. Trent, M. S., Pabich, W., Raetz, C. R. H., and Miller, S. I. (2001) J. Biol. Chem. 276, 9083-9092
28. Miller, J. R. (1972) Experiments in Molecular Genetics, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
29. Sambrook, J. G., and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, 3rd Ed., Cold Spring Harbor, Cold Spring Harbor, NY
30. Inoue, H., Nojima, H., and Okayama, H. (1990) Gene (Amst.) 96, 23-28
31. Shizuya, H., Birren, B., Kim, U. J., Mancino, V., Slepak, T., Tachiiri, Y., and Simon, M. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 8794-8797
32. Reynolds, C. M., Kalb, S. R., Cotter, R. J., and Raetz, C. R. H. (2005) J. Biol. Chem. 280, 21202-21211
33. Wang, R. F., and Kushner, S. R. (1991) Gene (Amst.) 100, 195-199
34. Garrett, T. A., Kadrmas, J. L., and Raetz, C. R. H. (1997) J. Biol. Chem. 272, 21855-21864
35. Basu, S. S., York, J. D., and Raetz, C. R. H. (1999) J. Biol. Chem. 274, 11139-11149
36. Belunis, C. J., and Raetz, C. R. H. (1992) J. Biol. Chem. 267, 9988-9997
37. Vorachek-Warren, M. K., Ramirez, S., Cotter, R. J., and Raetz, C. R. H. (2002) J. Biol. Chem. 277, 14194-14205
38. Odegaard, T. J., Kaltashov, I. A., Cotter, R. J., Steeghs, L., van der Ley, P., Khan, S., Maskell, D. J., and Raetz, C. R. H. (1997) J. Biol. Chem. 272, 19688-19696
39. Zhou, Z., Lin, S., Cotter, R. J., and Raetz, C. R. H. (1999) J. Biol. Chem. 274, 18503-18514
40. Brozek, K. A., Hosaka, K., Robertson, A. D., and Raetz, C. R. H. (1989) J. Biol. Chem. 264, 6956-6966
41. Brabetz, W., Muller-Loennies, S., Holst, O., and Brade, H. (1997) Eur. J. Biochem. 247, 716-724
42. Doerrler, W. T., and Raetz, C. R. H. (2002) J. Biol. Chem. 277, 36697-36705
43. Bligh, E. G., and Dyer, J. J. (1959) Can. J. Biochem. Physiol. 37, 911-917
44. Kanipes, M. I., Lin, S., Cotter, R. J., and Raetz, C. R. H. (2001) J. Biol. Chem. 276, 1156-1163
45. Guy-Caffey, J. K., Rapoza, M. P., Jolley, K. A., and Webster, R. E. (1992) J. Bacteriol. 174, 2460-2465
46. Osborn, M. J., and Munson, R. (1974) Methods Enzymol. 31, 642-653
47. Zhou, Z., White, K. A., Polissi, A., Georgopoulos, C., and Raetz, C. R. H. (1998) J. Biol. Chem. 273, 12466-12475
48. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
49. Laemmli, U. K. (1970) Nature 227, 680-685
50. Ribeiro, A. A., Zhou, Z., and Raetz, C. R. H. (1999) Magn. Res. Chem. 37, 620-630
51. Zhou, Z., Ribeiro, A. A., and Raetz, C. R. H. (2000) J. Biol. Chem. 275, 13542-13551
52. Costello, C. E., and Vath, J. E. (1990) Methods in Enzymology 193, 738-768
53. McClelland, M., Sanderson, K. E., Spieth, J., Clifton, S. W., Latreille, P., Courtney, L., Porwollik, S., Ali, J., Dante, M., Du, F., Hou, S., Layman, D., Leonard, S., Nguyen, C., Scott, K., Holmes, A., Grewal, N., Mulvaney, E., Ryan, E., Sun, H., Florea, L., Miller, W., Stoneking, T., Nhan, M., Waterston, R., and Wilson, R. K. (2001) Nature 413, 852-856
54. Nielsen, H., Brunak, S., and von Heijne, G. (1999) Protein Eng. 12, 3-9
55. Altschul, S. F., Madden, T. L., Schaffer, A. A., Zhang, J., Zhang, Z., Miller, W., and Lipman, D. J. (1997) Nucleic Acids Res. 25, 3389-3402
56. Moran, A. P., Lindner, B., and Walsh, E. J. (1997) J. Bacteriol. 179, 6453-6463
57. Rebeil, R., Ernst, R. K., Gowen, B. B., Miller, S. I., and Hinnebusch, B. J. (2004) Mol. Microbiol. 52, 1363-1373
58. Gibbons, H. S., Kalb, S. R., Cotter, R. J., and Raetz, C. R. H. (2005) Mol. Microbiol. 55, 425-440
59. Gunn, J. S., and Miller, S. I. (1996) J. Bacteriol. 178, 6857-6864
60. Guo, L., Lim, K. B., Gunn, J. S., Bainbridge, B., Darveau, R. P., Hackett, M., and Miller, S. I. (1997) Science 276, 250-253
61. Wosten, M. M., Kox, L. F., Chamnongpol, S., Soncini, F. C., and Groisman, E. A. (2000) Cell 103, 113-125
62. Garcia Vescovi, E., Soncini, F. C., and Groisman, E. A. (1996) Cell 84, 165-174
63. Miller, S. I., Kukral, A. M., and Mekalanos, J. J. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 5054-5058
64. Groisman, E. A., Chiao, E., Lipps, C. J., and Heffron, F. (1989) Proc. Natl. Acad. Sci. U. S. A. 86, 7077-7081
65. Groisman, E. A., Kayser, J., and Soncini, F. C. (1997) J. Bacteriol. 179, 7040-7045
66. Gunn, J. S., Lim, K. B., Krueger, J., Kim, K., Guo, L., Hackett, M., and Miller, S. I. (1998) Mol. Microbiol. 27, 1171-1182
67. Gunn, J. S. (2001) J. Endotoxin Res. 7, 57-62
68. Kawasaki, K., Ernst, R. K., and Miller, S. I. (2004) J. Endotoxin Res. 10, 439-444
69. Kawasaki, K., Ernst, R. K., and Miller, S. I. (2004) J. Biol. Chem. 279, 20044-20048
70. Kawasaki, K., Ernst, R. K., and Miller, S. I. (2005) J. Endotoxin Res. 11, 57-61
71. Vinogradov, E., Perry, M. B., and Conlan, J. W. (2002) Eur. J. Biochem. 269, 6112-6118
72. Darveau, R. P., Pham, T. T., Lemley, K., Reife, R. A., Bainbridge, B. W., Coats, S. R., Howald, W. N., Way, S. S., and Hajjar, A. M. (2004) Infect. Immun. 72, 5041-5051
73. Kawasaki, K., Ernst, R. K., and Miller, S. I. (2005) J. Bacteriol. 187, 2448-2457
74. Dekker, N., Tommassen, J., Lustig, A., Rosenbusch, J. P., and Verheij, H. M. (1997) J. Biol. Chem. 272, 3179-3184
75. Dekker, N. (2000) Mol. Microbiol. 35, 711-717
76. Snijder, H. J., Kingma, R. L., Kalk, K. H., Dekker, N., Egmond, M. R., and Dijkstra, B. W. (2001) J. Mol. Biol. 309, 477-489
77. Hagen, F. S., Grant, F. J., Kuijper, J. L., Slaughter, C. A., Moomaw, C. R., Orth, K., O'Hara, P. J., and Munford, R. S. (1991) Biochemistry 30, 8415-8423
78. Erwin, A. L., and Munford, R. S. (1990) J. Biol. Chem. 265, 16444-16449
79. Ahn, V. E., Lo, E. I., Engel, C. K., Chen, L., Hwang, P. M., Kay, L. E., Bishop, R. E., and Prive, G. G. (2004) EMBO J. 23, 2931-2941
80. Buchmeier, N., Bossie, S., Chen, C. Y., Fang, F. C., Guiney, D. G., and Libby, S. J. (1997) Infect. Immun. 65, 3725-3730
81. Ludwig, A., Tengel, C., Bauer, S., Bubert, A., Benz, R., Mollenkopf, H. J., and Goebel, W. (1995) Mol. Gen. Genet. 249, 474-486
82. Navarre, W. W., Halsey, T. A., Walthers, D., Frye, J., McClelland, M., Potter, J. L., Kenney, L. J., Gunn, J. S., Fang, F. C., and Libby, S. J. (2005) Mol. Microbiol. 56, 492-508
83. Miller, S. I., and Mekalanos, J. J. (1990) J. Bacteriol. 172, 2485-2490
84. Carlson, S. A., McCuddin, Z. P., and Wu, M. T. (2005) Microb. Pathog. 38, 181-187
85. Shi, Y., Latifi, T., Cromie, M. J., and Groisman, E. A. (2004) J. Biol. Chem. 279, 38618-38625
86. Stapleton, M. R., Norte, V. A., Read, R. C., and Green, J. (2002) J. Biol. Chem. 277, 17630-17637
87. Watson, P. R., Paulin, S. M., Bland, A. P., Libby, S. J., Jones, P. W., and Wallis, T. S. (1999) Infect. Immun. 67, 4950-4954
88. Kaneko, A., Mita, M., Sekiya, K., Matsui, H., Kawahara, K., and Danbara, H. (2002) Microbiol. Immunol. 46, 109-113
89. Suda, Y., Kim, Y. M., Ogawa, T., Yasui, N., Hasegawa, Y., Kashihara, W., Shimoyama, T., Aoyama, K., Nagata, K., Tamura, T., and Kusumoto, S. (2001) J. Endotoxin Res. 7, 95-104