The Salmonella typhi melittin resistance gene pqaB affects intracellular growth in PMA-differentiated U937 cells, polymyxin B resistance and lipopolysaccharide

Microbiology

Volumn 145, Issue 2, 1999, Pages 367-378

  Baker, Sarah J ^a   Gunn, John S ^b   Morona, Renato ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

PhoP Q regulon; PmrA B; Polymyxin B; pqa pqr; Virulence

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; MELITTIN; PHORBOL 13 ACETATE 12 MYRISTATE; POLYMYXIN B;

ARTICLE; BACTERIUM CULTURE; BACTERIUM MUTANT; GENE LOCUS; GENE SEQUENCE; HELA CELL; HUMAN; HUMAN CELL; MACROPHAGE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM; SILVER STAINING; TRANSPOSON; UNINDEXED SEQUENCE;

SALMONELLA TYPHI; SALMONELLA TYPHIMURIUM;

EID: 0032992831     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/13500872-145-2-367     Document Type: Article

References (58)

1. Alpuche-Aranda, C. M., Racoosin, E. L., Swanson. J. A. & Miller, S. I. (1994). Salmonella stimulate macrophage macropinocytosis and persist within spacious phagosomes. J Exp Med 179, 601-608.
2. Alpuche-Aranda, C. M., Berthiaume, E. P., Mock, B., Swanson, J. A. & Miller, S. I. (1995). Spacious phagosome formation within mouse macrophages correlates with Salmonella serotype pathogenicity and host susceptibility. Infect Immiu 63, 4456-4462.
3. Altschul, S. F., Gish, W., Miller, W., Myers, E. W. & Lipman, D. J. (1990). Basic local alignment search tool. J Mol Biol 215, 403-410.
4. Baker, S.J., Daniels, C. & Morona, R. (1997). PhoP/Q regulated genes in Salmonella typhi identification of melittin sensitive mutants. Microb Pathog 22, 165-179.
5. Barrow, P. A., Muggins, M. B. & Lovell, M. A. (1994). Host specificity of Salmonella infection in chickens and mice is expressed in vivo primarily at the level of the reticuloendothelial system. Infect Immun 62, 4602-4610.
6. Bastin, D. A., Lord, A. & Verma, N. K. (1997). Cloning and analysis of the glucosyl transferase gene encoding type I antigen in Shigella flexneri. FEMS Microbiol Lett 156, 133-139.
7. Bearson, B. L., Wilson, L. & Foster, J. W. (1998). A low pH-inducible, PhoPQ-dependent acid tolerance response protects Salmonella typhimurium against inorganic acid stress. J Bacteriol 180, 2409-2417.
8. Behlau, I. & Miller, S. I. (1993). A PhoP-repressed gene promotes Salmonella typhimurium invasion of epithelial cells. J Bacteriol 175, 4475-4484.
9. Buchmeier, N. A. & Heffron, F. (1989). Intracellular survival of wild-type Salmonella typhimurium and macrophage-sensitive mutants in diverse populations of macrophages. Infect Immun 57, 1-7.
10. Davis, R. W., Botstein, P. & Roth, J. R. (1980). Advanced Bacterial Genetics; a Manual for Genetic Engineering. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
11. Feingold, D. S. & Barbar, G. A. (1990). Nucleotide sugars. In Carbohydrates, pp. 39-78. Edited by P. M. Dey. London: Academic Press.
12. Fields, P. I., Swanson, R. V., Haidaris, C. G. & Heffron, F. (1986). Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc Natl Acad Sci USA 83, 5189-5193.
13. Fields, P. I., Groisman, E. A. & Heffron, F. (1989). A Salmonella locus that controls resistance to microbicidal proteins from phagocytic cells. Science 243, 1059-1062.
14. Galan, J. E. & Curtiss, R. D. (1989). Virulence and vaccine potential of phoP mutants of Salmonella typhimurium. Microb Pathog 6, 433-443.
15. 2- as an extracellular signal: environmental regulation of Salmonella virulence. Cell 84, 165-174.
16. Groisman, E. A. (1994). How bacteria resist killing by host-defense peptides. Trends Microbiol 15, 30-33.
17. Groisman, E. A. & Saier, M. H., Jr (1990). Salmonella virulence: new clues to intramacrophage survival. Trends Biochem Sci 15, 30-33.
18. Groisman, E. A., Saier, M. H., Jr & Ochman, H. (1992). Horizontal transfer of a phosphatase gene as evidence for mosaic structure of the Salmonella genome. EMBO J 11, 1309-1316.
19. 2- environments. J Bacteriol 179, 7040-7045.
20. Gunn, J. S. & Miller, S.I. (1996). PhoP-PhoQ activates transcription of PmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance. J Bacteriol 178, 6857-6864.
21. Gunn, J. S., Lim, K. B., Krueger, J., Kim, K., Guo, L., Hackett, M. & Miller, S. I. (1998). PmrA-PmrB-regulated genes necessary for 4-aminoarabinose lipid A modification and polymyxin resistance. Mot Microbiol 27, 1171-1182.
22. Guo, L., Lim, K. B., Gunn, J. S., Bainbridge, B., Darveau, R. P., Hackett, M. & Miller, S. I. (1997). Regulation of lipid A modifications by Salmonella typhimurium virulence genes phoP-phoQ. Science 276, 250-253.
23. Harris, P. & Ralph, P. (1985). Human leukemic models of myelomonocytic development: a review of the HL-60 and U937 cell lines. J Leukoc Biol 37, 407-422.
24. Hass, R., Bartels, H., Topley, N., Hadam, M., Kohler, L., Goppelt Strube, M. & Resch, K. (1989). TPA-induced differentiation and adhesion of U937 cells: changes in ultrastructure, cytoskeletal organization and expression of cell surface antigens. Eur J Cell Biol 48, 282-293.
25. Helander, I. M., Kilpelainen, I. & Vaara, M. (1994). Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study. Mol Microbiol 11, 481-487.
26. Hitchcock, P. J. & Brown, T. M. (1983). Morphological heterogeneity among Salmonella lipopolysaccharide chemotypes in silver-stained polyacrylamide gels. J Bacteriol 154, 269-277.
27. Hohmann, E. L., Oletta, C. A., Killeen, K. P. & Miller, S. I. (1996a). phoP/phoQ-deleted Salmonella typhi (Ty800). is a safe and immunogenic single-dose typhoid fever vaccine in volunteers. J Infect Dis 173, 1408-1414.
28. Hohmann, E. L., Oletta, C. A. & Miller, S. I. (1996b). Evaluation of a phoP/phoQ-deleted, aroA-deleted live oral Salmonella typhi vaccine strain in human volunteers. Vaccine 14, 19-24.
29. Hone, D. M., Tacket, C. O., Harris, A. M., Kay, B., Losonsky, G. & Levine, M. M. (1992). Evaluation in volunteers of a candidate live oral attenuated Salmonella typhi vector vaccine. J Clin Invest 90, 412-420.
30. Huan, P. T., Bastin, D. A., Whittle, B. L., Lindberg, A. A. & Verma, N. K. (1997a). Molecular characterization of the genes involved in O-antigen modification, attachment, integration and excision in Shigella flexneri bacteriophage SfV. Gene 195, 217-227.
31. Huan, P. T., Whittle, B. L., Bastin, D. A., Lindberg, A. A. & Verma, N. K. (1997b). Shigella flexneri type-specific antigen V: cloning, sequencing and characterization of the glucosyl transferase gene of temperate bacteriophage SfV. Gene 195, 207-216.
32. Johnston. C., Pegues, D. A., Hueck, C. J., Lee. A. & Miller, S. I. (1996). Transcriptional activation of Salmonella typhimurium invasion genes by a member of the phosphorylated response-regulator superfamily. Mol Microbiol 22, 715-727.
33. Kasahara, M., Nakata, A. & Shinagawa, H. (1991). Molecular analysis of the Salmonella typhimurium phoN gene, which encodes nonspecific acid phosphatase. J Bacteriol 173, 6760-6765.
34. Mavris, M., Manning, P. A. & Morona, R. (1997). Mechanism of bacteriophage SfII-mediated serotype conversion in Shigella flexneri. Mol Microbiol 26, 939-950.
35. Miller, S. I. (1991). PhoP/PhoQ: macrophage-specific modulators of Salmonella virulence? Mol Microbiol 5, 2073-2078.
36. Miller, S. I. & Mekalanos, J. J. (1990). Constitutive expression of the phoP regulon attenuates Salmonella virulence and survival within macrophages. J Bacteriol 172, 2485-2490.
37. Miller, S. I., Kukral, A. M. & Mekalanos, J. J. (1989). A two-component regulatory system (phoP phoQ) controls Salmonella typhimurium virulence. Proc Natl Acad Sci USA 86, 5054-5058.
38. Miller, S. I., Hohmann, E. L. & Pegues, D. A. (1995). Salmonella (including Salmonella typhi). In Principles and Practice of Infectious Diseases, pp. 2013-2033. Edited by G. L. Mandell, J. E. Bennett & R. Dolen. New York: Churchill Livingstone.
39. Mills, S. D. & Finlay, B. B. (1994). Comparison of Salmonella typhi and Salmonella typhimurium invasion, intracellular growth and localization in cultured human epithelial cells. Microb Pathog 17, 409-423.
40. Minta, J. O. & Pambrun, L. (1985). In vitro induction of cytologic and functional differentiation of the immature human monocyte-like cell line U-937 with phorbol myristate acetate. Am J Pathol 119, 111-126.
41. Monack, D. M., Raupach, B., Hromockyj, A. E. & Falkow, S. (1996). Salmonella typhimurium invasion induces apoptosis in infected macrophages. Proc Natl Acad Sci USA 93, 9833-9838.
42. Moreno, E., Mayer, H. & Moriyon, I. (1987). Characterization of a native polysaccharide hapten from Brucella melitensis. Infect Immun 55, 2850-2853.
43. Morona, R., Brown, M. H., Yeadon, J., Heuzenroeder, M. W. & Manning, P. A. (1991). Effect of lipopolysaccharide core synthesis mutations on the production of Vibrio cholerae O-antigen in Escherichia coli K-12. FEMS Microbiol Lett 66, 279-285.
44. Morona, R., van den Bosch, L. & Manning, P. A. (1995). Molecular, genetic and topological characterization of O-antigen chain length regulation in Shigella flexneri. J Bacteriol 177, 1059-1068.
45. Ochman, H., Gerber, A. S. & Haiti, D. L. (1988). Genetic applications of an inverse polymerase chain reaction. Genetics 120, 621-623.
46. Pedrinaci, S., Huelin, C., Patarroyo, M., Ruiz Cabello, F. & Garrido, F. (1989). Studies on CD1 la and CD18 molecules with two new monoclonal antibodies: differential myelomonocytic antigen expression of PMA treated HL60 and U937 cell lines. Hybridoma 8, 13-23.
47. Pegues, D. A., Hantman, M. J., Behlau, I. & Miller, S. I. (1995). PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion genes: evidence for a role in protein secretion. Mot Microbiol 17, 169-181.
48. Porter, E. M., van Dam, E., Valore, E. V. & Ganz, T. (1997). Broad-spectrum antimicrobial activity of human intestinal defensin 5. Infect Immun 65, 2396-2401.
49. Pulkkinen, W. S. & Miller, S. I. (1991). A Salmonella typhimurium virulence protein is similar to a Yersinia enterocolitica invasion protein and a bacteriophage lambda outer membrane protein. J Bacteriol 173, 86-93.
50. Selsted, M. E., Miller, S. I., Henschen. A. H. & Ouellette, A. J. (1992). Enteric defensins: antibiotic peptide components of intestinal host defense. J Cell Biol 118, 929-936.
51. Shyamala, V. & Ames, G. F. (1993). Single specific primerpolymerase chain reaction (SSP-PCR) and genome walking. In PCR Protocols: Current Methods and Applications, pp. 339-348. Edited by B. A. White. Totowa: Humana Press.
52. Soncini, F. C. & Groisman, E. A. (1996). Two-component regulatory systems can interact to process multiple environmental signals. J Bacteriol 178, 6796-6801.
53. Stroeher, U. H., Karageorgos, L. E., Brown, M. H., Morona, R. & Manning, P. A. (1995). A putative pathway for perosamine biosynthesis is the first function encoded within the rfb region of Vibrio cholerae O1. Gene 166, 33-42.
54. Sundstrom, C. & Nilsson, K. (1976). Establishment and characterization of a human histiocytic lymphoma cell line (U-937). Int J Cancer 17, 565-577.
55. Tenhaken, R. & Thulke, O. (1996). Cloning of an enzyme that synthesizes a key nucleotide-sugar precursor of hemicellulose biosynthesis from soybean: UDP-glucose dehydrogenase. Plant Physiol 112, 1127-1134.
56. Verma, N. K., Verma, D. J., Huan, P. T. & Lindberg, A. A. (1993). Cloning and sequencing of the glucosyl transferase-encoding gene from converting bacteriophage X (SFX) of Shigella flexneri. Gene 129, 99-101.
57. Vescovi, E. G., Sancini, F. C. & Groisman, E. A. (1994). The role of phoP/Q regulon in Salmonella virulence. Res Microbiol 145, 473-480.
58. Valdivia, R. H. & Falkow, S. (1996). Bacterial genetics by flow cytometry: rapid isolation of Salmonella typhimurium acid-inducible promoters by differential fluorescence induction. Mol Microbiol 22, 367-378.