Export of metabolites by the proteins of the DMT and RhtB families and its possible role in intercellular communication

Microbiology

Volumn 75, Issue 4, 2006, Pages 438-448

  Zakataeva, N P ^a   Kutukova, E A ^a   Gronskiy, S V ^a   Troshin, P V ^b   Livshits, V A ^a   Aleshin, V V ^c  

^a Ajinomoto Genetika Research Institute   (Russian Federation)

^b DARESBURY LABORATORY   (United Kingdom)

^c MOSCOW STATE UNIVERSITY   (Russian Federation)

Author keywords

Amino acids; Membrane proteins; Purines; Quorum sensing; Regulation of gene expression; Transport

Indexed keywords

BACTERIA (MICROORGANISMS); EUKARYOTA;

EID: 33746840107     PISSN: 00262617     EISSN: None     Source Type: Journal    
DOI: 10.1134/S0026261706040126     Document Type: Conference Paper

References (67)

1. Jack, D.L., Yang, N.M., and Saier, M.H., The Drug/Metabolite Transporter Superfamily, Eur. J. Biochem., 2001, vol. 268, no. 13, pp. 3620-3639.
2. Aleshin, V.V., Zakataeva, N.P., and Livshits, V.A., A New Family of Amino Acid Efflux Proteins, Trends Biochem. Sci., 1999, vol. 24, pp. 133-135.
3. Vrljić, M., Garg, J., Bellmann, A., Wachi, S., Freudl, R., Malecki, M.J., Sahm, H., Kozina, V.J., Eggeling, L., and Saier, M.H.., The LysE Superfamily: Topology of the Lysine Exporter LysE of Corynebacterium glutamicum, a Paradigm for a Novel Superfamily of Transmembrane Solute Translocators, J. Mol. Microbiol. Biotechnol, 1999, vol. 1, no. 2, pp. 327-336.
4. Vrljić, M., Sahm, H.., and Eggeling, L., A New Type of Transporter with a New Type of Cellular Function: L-Lysine export from Corynebacterium glutamicum, Mol. Microbiol., 1996, vol. 22, pp. 815-826.
5. Zakataeva, N.P., Aleshin, V.V., Tokmakova, I.L., Troshin, P.V., and Livshits, V.A., The Novel Transmembrane Escherichia coli Proteins Involved in the Amino Acid Efflux, FEBS Lett., 1999, vol. 452, no. 3, pp. 228-232.
6. Daßler, T., Maier, T., Winterhalter, C., and Böck, A., Identification of a Major Facilitator Protein from Escherichia coli Involved in Efflux of Metabolites of the Cysteine Pathway, Mol. Microbiol., 2000, vol. 36, pp. 1101-1112.
7. Livshits, V.A., Zakataeva, N.P., Nakanishi, K., Aleshin, V.V., Troshin, P.V., and Tokmakova, I.L., An Escherichia coli DNA Fragment Determining Increased Production of L-Amino Acids (Variants); a Method for Obtaining L-Amino Acids, RF Patent no. 2175351, October 2001.
8. Livshits, V.A., Zakataeva, N.P., Aleshin, V.V., and Vitushkina, M.V., Identification and Characterization of the New Gene rhtA Involved in Threonine and Homoserine Efflux in Escherichia coli, Res. Microbiol., 2003, vol. 154, pp. 123-135.
9. Livshits, V.A., Vitushkina, M.V., Mashko, S.V., Doroshenko, V.G., Biryukova, I.V., Katashkina, Zh.I., Skorokhodova, A.Yu., and Belareva, A.V., A Method for Obtaining L-Amino Acids; an Escherichia coli Strain Producing L-Amino Acids (Variants), RF Patent no. 2222596, January 2004.
10. Livshits, V.A., Vitushkina, M.V., Gusyatiner, M.M., Ziyatdinov, M.Kh., Akhverdyan, V.Z., Savrasova, E.A., Doroshenko, V.G., and Mashko, S.V., A Method for Obtaining L-Amino Acids; an Escherichia coli Strain Producing L-Amino Acids (Variants), RF Patent no. 2229513, May 2004.
11. Kutukova, E.A., Livshits, V.A., Altman, I.P., Ptitsyn, L.R., Zyiatdinov, M.H., Tokmakova, I.L., and Zakataeva, N.P., The yeaS (leuE) Gene of Escherichia coli Encodes an Exporter of Leucine, and the Lrp Protein Regulates Its Expression, FEBS Lett., 2005, vol. 579, pp. 4629-4634.
12. Livshits, V.A., Zakataeva, N.P., Gronskiy, S.V., Vitushkina, M.V., and Novikova, A.E., A Method for Obtaining Purine Nucleosides and Nucleotides; a Strain Producing Purine Nucleosides (Variants), RF Patent no. 2239656, November 2004.
13. Zakataeva, N.P., Livshits, V.A., and Gronskiy, S.V., A Method for Obtaining Purine Inosine and 5′-Inosinic Acid; an Escherichia coli Strain Producing Inosine, RF Patent no. 2244003, January 2005.
14. Gronskiy, S.V., Zakataeva, N.P., and Livshits, V.A., A Method for Obtaining Purine Inosine and 5′-Inosinic Acid; an Escherichia coli Strain Producing Inosine, RF Patent no. 2244004, January 2005.
15. Praillet, T., Reverchon, S., Robert-Baudouy, J., and Nasser, W., The PecM Protein Is Necessary for the DNA-Binding Capacity of the PecS Repressor, One of the Regulators of Virulence-Factor Synthesis in Erwinia chrysanthemi, FEMS Microbiol. Lett., 1997, vol. 154, no. 2, pp. 265-270.
16. Reverchon, S., Rouanet, C., Expert, D., and Nasser, W., Characterization of Indigoidine Biosynthetic Genes in Erwinia chrysanthemi and Role of This Blue Pigment in Pathogenicity, J. Bacteriol., 2002, vol. 184, no. 3, pp. 654-665.
17. Zavilgel'sky, G.B. and Manukhov, I.V., Quorum Sensing, or How Bacteria "Talk" to Each Other, Mol. Biol. 2001, vol. 35, no. 2, pp. 268-277
18. [Mol. Biol. (Engl. Transl.), vol. 35, no. 2, pp. 224-232].
19. Visick, K.L. and Fugua, C., Decoding Microbial Chatter: Cell-Cell Communication in Bacteria, J. Bacteriol., 2005, vol. 187, no. 16, pp. 5507-5519.
20. Kaper, J.B. and Sperandio, V., Bacterial Cell-to-Cell Signaling in the Gastrointestinal Tract, Infect. Immun., 2005, vol. 73, no. 6, pp. 3197-3209.
21. Kaplan, H.B. and Plamann, L., A Myxococcus xanthus Cell Density-Sensing System Required for Multicellular Development, FEMS Microbiol. Lett., 1996, vol. 139, nos. 2-3, pp. 89-95.
22. S (RpoS) Subunit of RNA Polymerase, Microbiol. Mol. Biol. Rev., 2002, vol. 66, no. 3, pp. 373-395.
23. Venturi, V., Control of rpoS Transcription in Escherichia coli and Pseudomonas: Why So Different?, Mol. Microbiol., 2003, vol. 49, no. 1, pp. 1-9.
24. Khmel, I.A., Regulation of Expression of Bacterial Genes in the Absence of Active Cell Growth, Genetika, 2005, vol. 41, no. 9, pp. 1183-1202
25. [Russ. J. Genet. (Engl. Transl.), vol. 41, no. 9, pp. 968-984].
26. Magnusson, L.U., Farewell, A., and Nystrom, T., ppGpp: A Global Regulator in Escherichia coli, Trends Microbiol., 2005, vol. 13, no. 5, pp. 236-242.
27. Braeken, K., Moris, M., Daniels, R., Vanderleyden, J., and Michiels, J., New Horizons for (p)ppGpp in Bacterial and Plant Physiology, Trends Microbiol., 2006, vol. 14, no. 1, pp. 45-54.
28. van Delden, C., Comte, R., and Bally, A.M., Stringent Response Activates Quorum Sensing and Modulates Cell Density-Dependent Gene Expression in Pseudomonas aeruginosa, J. Bacteriol., 2001, vol. 183, no. 18, pp. 5376-5384.
29. Calvo, J.M. and Matthews, R.G., The Leucine-Responsive Regulatory Protein, a Global Regulator of Metabolism in Escherichia coli, Microbiol. Rev., 1994, vol. 58, no. 3, pp. 466-490.
30. Evans, K., Passador, L., Srikumar, R., Tsang, E., Nezelzon, J., and Poole, K., Influence of the MexAB-OprM Multidrug Efflux System on Quorum Sensing in Pseudomonas aeruginosa, J. Bacteriol., 1998, vol. 180, pp. 5443-5447.
31. Pearson, J.P., van Delden, C., and Iglewski, B.H., Active Efflux and Diffusion Are Involved in Transport of Pseudomonas aeruginosa Cell-to-Cell Signals, J. Bacteriol., 1999, vol. 181, no. 4, pp. 1203-1210.
32. Maseda, H., Sawada, I., Saito, K., Uchiyama, H., Nakae, T., and Nomura, N., Enhancement of the MexAB-OprM Efflux Pump Expression by a Quorum-Sensing Autoinducer and Its Cancellation by a Regulator, MexT, of the mexEF-oprN Efflux Pump Operon in Pseudomonas aeruginosa, Antimicrob. Agents Chemother., 2004, vol. 48, no. 4, pp. 1320-1328.
33. Sawada, I., Maseda, H., Nakae, T., Uchiyama, H., Nomura, N., A Quorum-Sensing Autoinducer Enhances the mexAB-oprM Efflux-Pump Expression without the MexR-Mediated Regulation in Pseudomonas aeruginosa, Microbiol. Immunol., 2004, vol. 48, no. 5, pp. 435-439.
34. Rahmati, S., Yang, S., Davidson, A.L., and Zechiedrich, E.L., Control of the AcrAB Multidrug Efflux Pump by Quorum-Sensing Regulator SdiA, Mol. Microbiol., 2002. vol. 43, no. 3, pp. 677-685.
35. Franke, I., Resch, A., Daler, T., Maier, T., and Bock, A., YfiK from Escherichia coli Promotes Export of O-Acetylserine and Cysteine, J. Bacteriol., 2003, vol. 185, no. 4, pp. 1161-1166.
36. Bellmann, A., Vrljic, M., Patek, M., Sahm, H., Kramer, R., and Eggeling, L., Expression Control and Specificity of the Basic Amino Acid Exporter LysE of Corynebacterium glutamicum, Arch. Microbiol., 2001, vol. 147, no. 7, pp. 1765-1774.
37. Nandieni, R. and Gowrishankar, J., Evidence for an Arginine Exporter Encoded by yggA (argO) That Is Regulated by the LysR-Type Transcriptional Regulator ArgP in Escherichia coli, J. Bacteriol., 2004, vol. 186, no. 11, pp. 3539-3546.
38. Eggeling, L. and Sahm, H., New Ubiquitous Translocators: Amino Acid Export by Corynebacterium glutamicum and Escherichia coli, Arch. Microbiol., 2003, vol. 180, no. 3, pp. 155-160.
39. Surette, M.G., Miller, M.B., and Bassler, B.L., Quorum Sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: A New Family of Genes Responsible for Autoinducer Production, Proc. Natl. Acad. Sci. USA, 1999, vol. 96, no. 4, pp. 1639-1644.
40. Ahmer, B.M.M., Cell-to-Cell Signaling in Escherichia coli and Salmonella enterica, Mol. Microbiol., 2004, vol. 52, no. 4, pp. 933-945.
41. DeLisa, M.P., Wu, C.-F., Wang, L., Valdes, J.J., and Bentley, W.E., DNA Microarray-Based Identification of Genes Controlled by Autoinducer 2-Stimulated Quorum Sensing in Escherichia coli, J. Bacteriol., 2001, vol. 183, no. 18, pp. 5239-5247.
42. van Houdt, R., Aertsen, A., Moons, P., Vanoirbeek, K., and Michiels, C.W., N-Acyl-L-Homoserine Lactone Signal Interception by Escherichia coli, FEMS Microbiol. Lett., 2006, vol. 256.
43. Ullrich, M. and Bender, C.L., The Biosynthetic Gene Cluster for Coronamic Acid, an Ethylcyclopropyl Amino Acid, Contains Genes Homologous to Amino Acid-Activating Enzymes and Thioesterases, J. Bacteriol., 1994, vol. 176, no. 24, pp. 7574-7586.
44. Schuster, M., Lostroh, C.P., Ogi, T., and Greenberg, E.P., Identification, Timing, and Signal Specificity of Pseudomonas aeruginosa Quorum-Controlled Genes: A Transcriptome Analysis, J. Bacteriol., 2003, vol. 185, no. 7, pp. 2066-2079.
45. Wagner, V.E., Bushnell, D., Passador, L., Brooks, A.I., and Iglewski, B.H., Microarray Analysis of Pseudomonas aeruginosa Quorum-Sensing Regulons: Effects of Growth Phase and Environment, J. Bacteriol., 2003, vol. 185, no. 7, pp. 2080-2095.
46. Tani, T.H., Khodursky, A., Blumenthal, R.M., Brown, P.O., and Matthews, R.G., Adaptation to Famine: A Family of Stationary-Phase Genes Revealed by Microarray Analysis, Proc. Natl. Acad. Sci. USA, 2002, vol. 99, no. 21, pp. 13471-13476.
47. Buznikov, G.A. and Turpaev, T.M., Intracellular Functions of Neurotransmitiers: Phylogenetic and Ontogenetic Aspects, Zh. Evol Biokhim. Fiziol., 1987, vol. 23, no. 4, pp. 423-432.
48. Buznikov, G.A., Shmukler, Y.B., and Lauder, J.M., Changes in the Physiological Roles of Neurotransmitters during Individual Development, Neurosci. Behav. Physiol., 1999, vol. 29, no. 1, pp. 11-21.
49. Oleskin, A.V. and Kirovskaya, T.A., Research on Population Organization and Communication in Microorganisms, Mikrobiologiya, 2006, vol. 75, no. 4
50. [Microbiology (Engl. Transl.), vol. 75, no. 4].
51. Berninsone, P.M. and Hirschberg, C.B., Nucleotide Sugar Transporters of the Golgi Apparatus, Curr. Opin. Struct. Biol., 2000, vol. 10, no. 5, pp. 542-547.
52. Knappe, S., Flugge, U.-I., and Fischer, K., Analysis of the Plastidic Phosphate Translocator Gene Family in Arabidopsis and Identification of New Phosphate Translocator-Homologous Transporters, Classified by Their Putative Substrate-Binding Site, Plant Physiol., 2003, vol. 131, no. 3, pp. 1178-1190.
53. Hirschberg, C.B., Golgi Nucleotide Sugar Transport and Leukocyte Adhesion Deficiency II, J. Clin. Invest., 2001, vol. 108, no. 1, pp. 3-6.
54. Hwang, H.Y. and Horvitz, H.R., The SQV-1 UDP-Glucuronic Acid Decarboxylase and the SQV-7 Nucleotide-Sugar Transporter May Act in the Golgi Apparatus To Affect Caenorhabditis elegans Vulval Morphogenesis and Embryonic Development, Proc. Natl. Acad. Sci. USA, 2002, vol. 99, no. 22, pp. 14218-14223.
55. Ishikawa, H.O., Higashi, S., Ayukawa, T., Sasamura, T., Kitagawa, M., Harigaya, K., Aoki, K., Ishida, N., Sanai, Y., and Matsuno, K., Notch Deficiency Implicated in the Pathogenesis of Congenital Disorder of Glycosylation IIc, Proc. Natl. Acad. Sci. USA, 2005, vol. 102, no. 51, pp. 18532-18537.
56. Sacks, D.L., Modi, G., Rowton, E., Späth, G., Epstein, L., Turco, S.J., and Beverley, S.M., The Role of Phosphoglycans in Leishmania-Sand Fly Interactions, Proc. Natl. Acad. Sci. USA, 2000, vol. 97, no. 1, pp. 406-411.
57. Niewiadomski, P., Knappe, S., Geimer, S., Fischer, K., Schulz, B., Unte, U.S., Rosso, M.G., Ache, P., Flugge, U.-I., and Schneider, A., The Arabidopsis Plastidic Glucose-6-Phosphate/Phosphate Translocator GPT1 Is Essential for Pollen Maturation and Embryo Sac Development, Plant Cell, 2005, vol. 17, no. 3, pp. 760-775.
58. Gronskiy, S.V., Zakataeva, N.P., Vitushkina, M.V., Ptitsyn, L.R., Altman, I.B., Novikova, A.E., and Livshits, V.A., The yicM (nepl) Gene of Escherichia coli Encodes a Major Facilitator Superfamily Protein Involved in Efflux of Purine Ribonucleosides, FEMS Microbiol. Lett., 2005, vol. 250, no. 1, pp. 39-47.
59. Yang, S., Clayton, S.R., and Zechiedrich, E.L., Relative Contributions of the AcrAB, MdfA and NorE Efflux Pumps to Quinolone Resistance in Escherichia coli, J. Antimicrob. Chemother., 2003, vol. 51, no. 3, pp. 545-556.
60. Yang, S., Lopez, C.R., and Zechiedrich, E.L., Quorum Sensing and Multidrug Transporters in Escherichia coli, Proc. Natl. Acad Sci. USA, 2006, vol. 103, no. 7, pp. 2386-2391.
61. Ullmann, A. and Danchin, A., Role of Cyclic AMP in Bacteria, Adv. Cyclic Nucleotide Res., 1983, vol. 30, pp. 1-53.
62. Mann, S.K. and Firtel, R.A., cAMP-Dependent Protein Kinase Differentially Regulates Prestalk and Prespore Differentiation during Dictyostelium Development, Development, 1993, vol. 119, no. 1, pp. 135-146.
63. Williams, M. and Jarvis, M.F., Purinergic and Pyrimidinergic Receptors as Potential Drug Targets, Biochem. Pharmacol., 2000, vol. 59, no. 10, pp. 1173-1185.
64. Jenal, U., Cyclic Di-Guanosine-Monophosphate Comes of Age: A Novel Secondary Messenger Involved in Modulating Cell Surface Structures in Bacteria?, Curr. Opin. Microbiol., 2004, vol. 7, no. 2, pp. 185-191.
65. Römling, U., Gomelsky, M., and Galperin, M.Y., c-di-GMP: The Dawning of a Novel Bacterial Signaling System, Mol. Microbiol., 2005, vol. 57, no. 3, pp. 629-639.
66. Arnold, C.N., McElhanon, J., Lee, A., Leonhart, R., and Siegele, D.A., Global Analysis of Escherichia coli Gene Expression during the Acetate-Induced Acid Tolerance Response, J. Bacteriol., 2001, vol. 183, no. 7, pp. 2178-2186.
67. Rinas, U., Hellmuth, K., Kang, R., Seeger, A., and Schlieker, H., Entry of Escherichia coli into Stationary Phase Is Indicated by Endogenous and Exogenous Accumulation of Nucleobases, Appl. Environ. Microbiol., 1995, vol. 61, no. 12, pp. 4147-4151.