The course of uncarinic acid E-induced apoptosis of HepG2 cells from damage to DNA and p53 Activation to Mitochondrial Release of Cytochrome c

Biological and Pharmaceutical Bulletin

Volumn 29, Issue 8, 2006, Pages 1639-1644

  Zhao, Minghong ^a,b   Guo, Tao ^a   Wang, Minwei ^b   Zhao, Qingchun ^a   Liu, Yanxia ^b   Sun, Xuehui ^a   Wang, Huailiang ^c   Hou, Yue ^b  

^a GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; HepG2 cell; Uncarinic acid E

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE; CASPASE 3 INHIBITOR; CASPASE 6 INHIBITOR; CASPASE INHIBITOR; CYTOCHROME C; GELSEMIUM ELEGANS EXTRACT; MITOGEN ACTIVATED PROTEIN KINASE; PLANT EXTRACT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE C; PROTEIN P53; UNCARINIC ACID E; UNCLASSIFIED DRUG; WORTMANNIN;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL DEATH; CELL STRAIN HEPG2; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; GELSEMIUM; HUMAN; HUMAN CELL; MITOCHONDRION; PROTEIN EXPRESSION; PROTEIN SECRETION;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; CYTOCHROMES C; DNA DAMAGE; ELECTROPHORESIS, AGAR GEL; ESTERS; HUMANS; MITOCHONDRIA; PROTEIN KINASE C; TRITERPENES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33746701390     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.29.1639     Document Type: Article

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