Synthesis of a thymidine-derived acylsilane: A new synthetic intermediate towards thymidine analogues

Synthesis

Volumn , Issue 14, 2006, Pages 2343-2348

  Wegert, Anita ^a   Behr, Jean Bernard ^b   Hoffmann, Norbert ^b   Miethchen, Ralf ^a   Portella, Charles ^b   Plantier Royon, Richard ^b  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

Author keywords

Acylsilanes; Nucleoside analogues; Oxidation; Photo Brook rearrangement; Thymidine

Indexed keywords

CARBON; NUCLEIC ACIDS; ORGANIC COMPOUNDS; OXIDATION; SYNTHESIS (CHEMICAL);

ACYLSILANES; NUCLEOSIDE ANALOGUES; PHOTO-BROOK REARRANGEMENT; THYMIDINE;

SILANES;

3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' (1'' HYDROXY 1'' TRIMETHYLSILYLBUT 3'' ENYL)THYMIDINE; 3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' (1'' HYDROXY 1'' TRIMETHYLSILYLMETHYL)THYMMIDINE; 3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' (2'' TRIMETHYLSILYL 1'',3'' DITHIAN 2'' YL)THYMIDINE; 3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' (TRIMETHYLSILYLCARBONYL)THYMIDNE; 3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' CARBOXYTHYMIDINE; 3' 0 TERT BUTYLDIMETHYLSILYL 5' DEOXY 5' FORMYLTHYMIDINE; THYMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; OXIDATION; SYNTHESIS;

EID: 33746616492     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942438     Document Type: Article

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