Facilitating antidepressant-like actions of estrogens are mediated by 5-HT1A and estrogen receptors in the rat forced swimming test

Psychoneuroendocrinology

Volumn 31, Issue 8, 2006, Pages 905-914

  Estrada Camarena, E ^a   Lopez Rubalcava C ^b   Fernandez Guasti A ^b  

^a INSTITUTO NACIONAL DE PSIQUIATRÍA RAMÓN DE LA FUENTE MUÑIZ   (Mexico)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

17 estradiol; 5 HT1A receptor; Antidepressants; Estrogen receptor; Fluoxetine; Forced swimming test

Indexed keywords

11 [4 [[5 [(4,4,5,5,5 PENTAFLUOROPENTYL)SULFONYL]PENTYL]OXY]PHENYL] ESTRADIOL; ESTRADIOL; ESTROGEN RECEPTOR; FLUOXETINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PROSTAGLANDIN E; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CATECHOLAMINE METABOLISM; CLIMBING; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG EFFICACY; DRUG RECEPTOR BINDING; ESTROGEN ACTIVITY; FEMALE; FORCED SWIMMING TEST; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; RAT STRAIN; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; SEROTONIN METABOLISM; SWIMMING;

ANIMALS; ANTIDEPRESSIVE AGENTS; DEPRESSION; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGENS; FEMALE; FLUOXETINE; MOTOR ACTIVITY; PIPERAZINES; PYRIDINES; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, ESTROGEN; SEROTONIN ANTAGONISTS; SEROTONIN UPTAKE INHIBITORS; SWIMMING;

EID: 33746587806     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2006.05.001     Document Type: Article

References (64)

1. Alves S., Weiland N., Hayashi S., and McEwen B. Immunocytochemical localization of nuclear estrogen receptors and progestin receptors within the rat dorsal raphe nucleus. J. Comp. Neurol. 391 (1998) 322-334
2. Bernardi M., Vergoni A., Sandrini M., Tagliavini S., and Bertolini A. Influence of ovariectomy, estradiol and progesterone on the behavior of mice in experimental model of depression. Physiol. Behav. 45 (1989) 1067-1068
3. Blier P., and Ward N. Is there a role for 5-HT1A receptor agonist in the treatment of depression?. Biol. Psychiat. 53 (2003) 193-203
4. Castro E., Diaz A., del Olmo E., and Pazos A. Chronic fluoxetine induces opposite changes in G protein coupling at pre and post-synaptic 5-HT1A receptors in rat brain. Neuropharmacology 44 (2003) 93-101
5. Chang A., and Chang S. Nongenomic steroidal modulation of high-affinity serotonin transport. Biochimica et Biophysica Acta 1417 (1999) 157-166
6. Cryan J., and Leonard B. 5-HT1A and beyond: the role of serotonin and its receptors in depression and the antidepressant response. Hum. Psychopharmacol. Clin. Exp. 15 (2000) 113-135
7. Cryan J., Valentino R., and Lucki I. Assessing substrates underlying the behavioral effects of antidepressants using the modifying rats forced swimming test. Neurosci. Biobehav. Rev. 29 (2005) 547-569
8. Dalla C., Antoniou K., Papadopoulou-Daifoti Z., Balthazart J., Bakker, et al. Oestrogen-deficient female aromatase knockout (ArKO) mice exhibit depressive-like symtomatology. Eur. J. Neurosci. 20 (2004) 217-228
9. Dawson L.A., and Nguyen H.G. Effects of the 5-HT1A receptor antagonist on fluoxetine induces changes in extracellular 5-HT concentration in rat frontal cortex. Eur. J. Pharmacol. 345 (1998) 41-46
10. Dawson L.A., and Nguyen H.G. The role of the 5-HT1A and 5-HT1B/D receptors in the modulation of acute fluoxetine induces changes in extracellular 5-HT: mechanism of action of (±) pindolol. Neuorpharmacology 39 (2000) 1044-1052
11. Detke M., Rickels M., and Lucki I. Active behaviors in the rat forced swimming test differentially activated by serotonergic and noradrenergic antidepressants. Psychopharmacology 121 (1995) 66-72
12. Espejo E., and Miñano F. Prefrontocortical dopamine depletion induces antidepressant-like effects in rats and alters the profile of desipramine during Porsolt's test. Neuroscience 88 (1999) 609-615
13. Estrada-Camarena E., Fernández-Guasti A., and López-Rubalcava L. Antidepressant-like effect of different estrogenic compounds in the forced swimming test. Neuropsychopharmacology 28 (2003) 830-838
14. Estrada-Camarena E., Fernández Guasti A., and López-Rubalcava C. Participation of the 5-HT1A receptor in the antidepressant-like effect of estrogens in the forced swimming test. Neuropsychopharmacology 31 (2006) 247-255
15. Fang H., Tong W., Shi L.M., Blair R., Perkins R., Branham W., Hass B., Xie Q., Dial S., Moland C., and Sheehan D. Structure-activity relationships for a large diverse of natural, synthetic, and environmental estrogens. Chem. Res. Toxicol. 14 (2001) 280294
16. Fink G., Sumner B., Rosie R., Grace O., and Quinn J. Estrogen control of central transmisión: effect on mood, mental state, and memory. Cell Mol. Neurobiol. 16 (1996) 325-344
17. Forster E., Cliffe I., Bill D., Dover G., Jones D., Reilly Y., and Fletcher A. A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY 100635. Eur. J. Pharmacol. 281 (1995) 81-88
18. Galea L., Wide J., and Barr A. Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression. Behavioral. Brain. Res. 122 (2001) 1-9
19. Halbreich U., and Kahn L. Role of estrogen in the aetiology and treatment of mood disorders. CNS Drugs 15 (2001) 797-817
20. Kelly M., and Wagner E.J. Estrogen modulation of G-protein coupled receptors. TEM 10 (1999) 369-374
21. Kobayashi T., Tamura M., Hayashi M., Katsura Y., Tanabe H., Ohta T., and Komoriya K. Elevation of tail skin temperature in ovariectomized rats in relation to menopausal hot flushes. Am. J. Physiol. Regul. Integr. Comp. Physiol. 278 4 (2000) R863-R869
22. Lee S., and McEwen B. Neuroptrophic and neuroprotective actions of estrogens and their therapeutic implications. Annu. Rev. Pharmacol. Toxicol 41 (2001) 569-591
23. Levin E. Cellular functions of plasma membrane estrogen receptors. Steroids 67 (2002) 471-475
24. 1A receptors. J. Pharmacol. Exp. Ther. 282 (1997) 1581-1590
25. 11- proteins. Brain Res. 775 (1997) 225-228
26. Lu N., and Bethea C. Ovarian steroid regulation of 5-HT1A receptor binding and G-protein activation in female monkeys. Neuropsychopharmacology 27 (2002) 12-24
27. Lu H., Ozawa H., Nishi M., Ito T., and Kawata M. Serotonergic neurons in the dorsal raphe nucleus that project into the medial preoptic area contain oestrogen receptor β. J. Neuroendocrinol. 13 (2001) 839-845
28. Lucki I. The forced swimming test as a model for core and component behavioral effects of antidepressant drugs. Behav. Pharmacol. 8 (1997) 523-532
29. 1A receptors. Psychopharmacology 165 (2002) 60-66
30. McEwen B. Estrogens effects on the brain: multiple sites and molecular mechanisms. J. Appl. Physiol. 91 (2001) 2785-2801
31. McEwen B., and Alves S. Estrogen actions in the central nervous system. Endocrine. Rev. 20 (1999) 279-307
32. 35S] GTPγS binding. Brain Res. 859 (2000) 326-333
33. Mize A., and Alper R. Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17β-estradiol in vitro requires protein kinases A and C. Neuroendocrinology 76 (2002) 339-347
34. 1A receptor function. Neuroendocrinology 73 (2001) 166-174
35. Mize A.L., Young L.J., and Alper R.H. Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780. Neuropharmacology 44 (2003) 584-591
36. Oppenheim G. Estrogen in the treatment of depression: neuropharmacological mechanisms. Biol. Psychiat. 18 (1983) 721-725
37. 1A receptor mRNA expression in the limbic system of female rats. Mol. Brain Res. 55 (1998) 169-172
38. Porsolt R., and Lenegre A. Behavioral models of depression. In: Elliot J., Heal D., and Maisden C. (Eds). Experimental Approaches to Anxiety and Depression. first Ed (1992), Wiley, New York 73-85
39. Porsolt R., Le Pichon M., and Jalfre M. Depression: a new animal model sensitive to antidepressant treatments. Nature 266 (1977) 730-732
40. Porsolt R., Anton G., Blavet N., Deniel M., and Jalfre M. Behavioral despair in rats: a new model sensitive to antidepressant treatment. Eur. J. Pharmacol. 47 (1978) 379-391
41. Quesada A., and Etgen A.M. Tyrosine kinase effects on adrenoceptor-stimulated cyclic AMP accumalation in preoptic area and hypothalamus of female rats: modulation by estradiol. Brain Res. 861 (2000) 117-125
42. i3 proteins in the hypothalamus. Neuropharmacology 39 (2000) 1823-1832
43. Rachman I., Unnerstall J., Pfaff D., and Cohen R. Estrogen alters behavior and forbrain c-fos expression in ovariectomized rats subjected to the forced swim test. Proc. Natl. Acad. Sci. 95 (1998) 13941-13946
44. Raap D., and Van de Kar L. Selective serotonin reuptake inhibitors and neuroendocrine function. Life Sci. 65 (1999) 1217-1235
45. Rocha B.A., Fleischer R., Schaffer J.M., Rohrer S.P., and Hickey G.J. 17 Beta-estradiol-induced antidepressant-like effect in the forced swim test is absent in estrogen receptor-beta knockout (BERKO) mice. Psychopharmacology (Berl) 179 3 (2005) 637-643
46. Rupprecht R., di Michele F., Hermann B., Strhöle A., Lancel M., Romeo E., and Holsboer F. Neuroactive steroids: molecular mechanisms of action and implications for neuropsychopharmacology. Brain Res. Rev. 37 (2001) 59-67
47. Schneider L., Small G., Hamilton S., Bystrisky A., Nemeroff C., and Meyers B. Estrogen replacement and response to fluoxetine in surgically menopauseal women. Am. J. Geriatr. Psychiat. 5 (1997) 97-106
48. Schneider L., Small G., and Clary C.M. Estrogen replacement therapy and antidepressant response to sertraline in older depressed women. Am. J. Geriatr. Psychiat. 9 (2001) 393-399
49. Serres F., Muma N., Raap D., García F., Battaglia G., and Van de Kar L. Coadminsitration of 5-hydroxytryptamine1A antagonist WAY-100635 prevents fluoxetine-induced desensitization of postsynaptic 5-hydroxytryptamine1A receptors in hypothalamus. J. Phamacol. Exp. Ther. 294 (2000) 296-301
50. Shen C., Li H., and Meller E. repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S] GTP gamma S binding in rat brain regions. Neuropharmacology 42 (2002) 1031-1038
51. Sheng Z., Kawano J., Yanai A., Fujinaga R., Tanaka M., Watanabe Y., and Shinoda K. Expression of estrogen receptors (α, β) and androgen receptor in serotonin neurons of the rat and mouse dorsal raphe nuclei: sex and species differences. Neurosci. Res. 49 (2004) 185-196
52. Stahl S. Basic psychopharmacology of antidepressants. Part 1: antidepressants have seven distinct mechanisms of action. J. Clin. Psychiat. 59 (1998) 5-14
53. Soares C., Almeida O., Joffe H., and Cohen L. Efficacy of estradiol for the treatment of depressive disorders in perimenopausal women. Arch. Gen. Psychiat. 58 (2001) 529-534
54. Sumner B., Grant K., Rosie R., Hegele-Hartung Ch., Frtizemeier K.-H., and Fink G. Effects of tamoxifen on serotonin transporter and 5-HT2A receptor binding sities and RNAm levels in the brain of ovariectomized rats with or without acute estradiol replacement. Mol. Brain Res. 73 (1998) 119-128
55. Torand-Allerand C.D., Singh M., and Sétalo G. Novel mechanism s of estrogen action in the brain: new players in a old story. Front Neuroendocrinol. 20 (1999) 97-121
56. Vagell M.E., and McGinnis M. Effects of he antiestrogen, RU 58668, on the female sexual behavior in rats. Brain Res. Bull. 41 (1996) 121-124
57. Vagell M.E., and McGinnis M.Y. Inhibition of brain oestrogen receptors by RU 58668. J. Neuroendocrinol. 9 (1997) 797-800
58. Vagell M.E., and McGinnis M.Y. The role of gonadal steroid receptor activation in the restoration of sociosexual behavior in adult male rats. Horm Behav. 33 (1998) 163-179
59. Van de Velde P., Nique F., Bouchoux F., Brémaud J., Hameau M.-C., Lucas D., Moratille C., Viet S., Philibert D., and Teutsch G. RU 58668, a new pure antiestrogen inducing a regression of human mammary carcinoma implanted in nude mice. J. Steriod Biochem Mol. Biol. 48 (1994) 187-195
60. Van de Velde P., Nique F., Brémaud j., Hameau M.-C., Philibert D., and Teutsch G. Exploration of the therapeutic potential of the antiestrogen RU 58668 in the breast cancer treatment. In: steroid receptors and antihormones. Ann. NY Acad. Sci. 761 (1995) 164-175
61. Van de Velde P., Nique F., Planchon P., Prévost G., Brémaud j., Hameau M.-C., Magnien V., Philibert D., and Teutsch G. RU: 58668: Further in vitro and in vivo pharmacological data related to its antitumoral activity. J. Steroid. Biochem. Mol. Biol. 59 (1996) 449-457
62. Walf A., Rhodes M.E., and Frye C.A. Antidepressant effects of ERβ-selective estrogen receptor modulators in the forced swimming test. Pharmacol. Biochem. Behav. 78 (2004) 523-529
63. Wehling M. Specific nongenomic actions of steriod hormones. Annu. Rev. physiol. 59 (1997) 365-393
64. Wilson M., Dwyer K., and Roy E. Direct effects of ovarian hormones on antidepressant binding sites. Brain Res. 22 (1988) 181-185