Direct organocatalytic asymmetric epoxidation of α,β-unsaturated aldehydes

Tetrahedron Letters

Volumn 47, Issue 1, 2006, Pages 99-103

  Sundén, Henrik ^a   Ibrahem, Ismail ^a   Córdova, Armando ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

, Unsaturated aldehydes; Asymmetric catalysis; Epoxides; Proline derivatives

Indexed keywords

ALDEHYDE; ALPHA,ALPHA DIPHENYL 2 PROLINOL; AMINO ACID DERIVATIVE; HYDROGEN PEROXIDE; IMIDAZOLE DERIVATIVE; OXYGEN; PEROXIDE; PROLINE DERIVATIVE; PYRROLIDINE DERIVATIVE; SODIUM DERIVATIVE; SODIUM PERCABONATE; SOLVENT; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; CATALYSIS; CATALYST; CHIRALITY; COMMERCIAL PHENOMENA; ENVIRONMENTAL FACTOR; EPOXIDATION;

EID: 28544436605     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2005.10.128     Document Type: Article

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55. 2 (0.3 mmol, 50% aqueous solution). The reaction was vigorously stirred at room temperature and monitored by chiral-phase GC analyses. The formation and enantiomeric excess of 2a was determined on a Chromasil CP-Chirasil-Dex CB-column.
56. 2O). The reaction was vigorously stirred at room temperature and monitored by chiral-phase GC analyses. The formation and enantiomeric excess of the desired epoxides 2 were determined on a Chromasil CP-Chirasil-Dex CB-column.
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