Asymmetric carbon-carbon bond formations in conjugate additions of lithiated N-Boc allylic and benzylic amines to nitroalkenes: Enantioselective synthesis of substituted piperidines, pyrrolidines, and pyrimidinones

Journal of the American Chemical Society

Volumn 124, Issue 39, 2002, Pages 11689-11698

  Johnson, Timothy A ^a   Jang, Doo Ok ^b   Slafer, Brian W ^a   Curtis, Michael D ^a   Beak, Peter ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b Yonsei University Wonju   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ENANTIOMERS;

CHEMICAL BONDS; ENZYME INHIBITION; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

AMINES;

3 HYDROXY 4 PHENYLPIPERIDINE; ALKENE DERIVATIVE; ALLYL COMPOUND; ANTIDEPRESSANT AGENT; ASPARTIC PROTEINASE INHIBITOR; BENZYLAMINE DERIVATIVE; CARBAMIC ACID DERIVATIVE; FEMOXETINE; NITRO DERIVATIVE; PIPERIDINE DERIVATIVE; PYRIMIDINONE DERIVATIVE; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL BOND; CHEMICAL MODIFICATION; CHEMICAL STRUCTURE; DIASTEREOISOMER; ENANTIOSELECTIVITY; SYNTHESIS;

ALKENES; AMINES; BENZYLAMINES; FORMIC ACID ESTERS; LITHIUM; NITRO COMPOUNDS; ORGANOMETALLIC COMPOUNDS; PIPERIDINES; PYRIMIDINONES; PYRROLIDINES; STEREOISOMERISM;

EID: 0037009997     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0271375     Document Type: Article

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