-
1
-
-
0037115914
-
Homologous repair of DNA damage and tumorigenesis: The BRCA connection
-
Jasin M. Homologous repair of DNA damage and tumorigenesis: The BRCA connection. Oncogene 2002; 21:8981-93.
-
(2002)
Oncogene
, vol.21
, pp. 8981-8993
-
-
Jasin, M.1
-
2
-
-
0034707053
-
In search of the tumour-suppressor functions of BRCA1 and BRCA2
-
Scully R, Livingston DM. In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature 2000; 408:429-32.
-
(2000)
Nature
, vol.408
, pp. 429-432
-
-
Scully, R.1
Livingston, D.M.2
-
3
-
-
0037169354
-
Cancer susceptibility and the functions of BRCA1 and BRCA2
-
Venkitaraman AR. Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 2002; 108:171-82.
-
(2002)
Cell
, vol.108
, pp. 171-182
-
-
Venkitaraman, A.R.1
-
4
-
-
25444517122
-
Good timing in the cell cycle for precise DNA repair by BRCA1
-
Durant ST, Nickoloff JA. Good timing in the cell cycle for precise DNA repair by BRCA1. Cell Cycle 2005; 4:1216-22.
-
(2005)
Cell Cycle
, vol.4
, pp. 1216-1222
-
-
Durant, S.T.1
Nickoloff, J.A.2
-
5
-
-
0038700698
-
Molecular views of recombination proteins and their control
-
West SC. Molecular views of recombination proteins and their control. Nat Rev Mol Cell Biol 2003; 4:435-45.
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 435-445
-
-
West, S.C.1
-
6
-
-
0031472370
-
Association of BRCA1 with Rad51 in mitotic and meiotic cells
-
Scully R, Chen J, Plug A, Xiao Y, Weaver D, Feunteun J, Ashley T, Livingston DM. Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell 1997; 88:265-75.
-
(1997)
Cell
, vol.88
, pp. 265-275
-
-
Scully, R.1
Chen, J.2
Plug, A.3
Xiao, Y.4
Weaver, D.5
Feunteun, J.6
Ashley, T.7
Livingston, D.M.8
-
7
-
-
0031466027
-
RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2
-
Wong AK, Pero R, Ormonde PA, Tavtigian SV, Bartel PL. RAD51 interacts with the evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J Biol Chem 1997; 272:31941-4.
-
(1997)
J Biol Chem
, vol.272
, pp. 31941-31944
-
-
Wong, A.K.1
Pero, R.2
Ormonde, P.A.3
Tavtigian, S.V.4
Bartel, P.L.5
-
8
-
-
15844373362
-
CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair
-
Esashi F, Christ N, Gannon J, Liu Y, Hunt T, Jasin M, West SC. CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair. Nature 2005; 434:598-604.
-
(2005)
Nature
, vol.434
, pp. 598-604
-
-
Esashi, F.1
Christ, N.2
Gannon, J.3
Liu, Y.4
Hunt, T.5
Jasin, M.6
West, S.C.7
-
9
-
-
0036752956
-
BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis
-
Kojic M, Kostrub CF, Buchman AR, Holloman WK. BRCA2 homolog required for proficiency in DNA repair, recombination, and genome stability in Ustilago maydis. Mol Cell 2002; 10:683-91.
-
(2002)
Mol Cell
, vol.10
, pp. 683-691
-
-
Kojic, M.1
Kostrub, C.F.2
Buchman, A.R.3
Holloman, W.K.4
-
10
-
-
16244407723
-
RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair
-
Martin JS, Winkelmann N, Petalcorin MI, McIlwraith MJ, Boulton SJ. RAD-51-dependent and -independent roles of a Caenorhabditis elegans BRCA2-related protein during DNA double-strand break repair. Mol Cell Biol 2005; 25:3127-39.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3127-3139
-
-
Martin, J.S.1
Winkelmann, N.2
Petalcorin, M.I.3
McIlwraith, M.J.4
Boulton, S.J.5
-
11
-
-
1942471131
-
Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1
-
Siaud N, Dray E, Gy I, Gerard E, Takvorian N, Doutriaux MP. Brca2 is involved in meiosis in Arabidopsis thaliana as suggested by its interaction with Dmc1. EMBO J 2004; 23:1392-401.
-
(2004)
EMBO J
, vol.23
, pp. 1392-1401
-
-
Siaud, N.1
Dray, E.2
Gy, I.3
Gerard, E.4
Takvorian, N.5
Doutriaux, M.P.6
-
12
-
-
14144253224
-
The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction
-
Yang H, Li Q, Fan J, Holloman WK, Pavletich NP. The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA-ssDNA junction. Nature 2005; 433:653-7.
-
(2005)
Nature
, vol.433
, pp. 653-657
-
-
Yang, H.1
Li, Q.2
Fan, J.3
Holloman, W.K.4
Pavletich, N.P.5
-
14
-
-
29944434644
-
Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes
-
Greenberg RA, Sobhian B, Pathania S, Cantor SB, Nakatani Y, Livingston DM. Multifactorial contributions to an acute DNA damage response by BRCA1/BARD1-containing complexes. Genes Dev 2006; 20:34-46.
-
(2006)
Genes Dev
, vol.20
, pp. 34-46
-
-
Greenberg, R.A.1
Sobhian, B.2
Pathania, S.3
Cantor, S.B.4
Nakatani, Y.5
Livingston, D.M.6
-
15
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A, Fernandez-Capetillo O, Kruhlak MJ, Pilch DR, Staudt DW, Lee A, Bonner RF, Bonner WM, Nussenzweig A. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat Cell Biol 2003; 5:675-9.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
16
-
-
31144452919
-
Assessing the link between BACH1 and BRCA1 in the FA pathway
-
Cantor SB, Andreassen PR. Assessing the link between BACH1 and BRCA1 in the FA pathway. Cell Cycle 2006; 5:164-7.
-
(2006)
Cell Cycle
, vol.5
, pp. 164-167
-
-
Cantor, S.B.1
Andreassen, P.R.2
-
17
-
-
10344264478
-
BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation
-
Turner JM, Aprelikova O, Xu X, Wang R, Kim S, Chandramouli GV, Barrett JC, Burgoyne PS, Deng CX. BRCA1, histone H2AX phosphorylation, and male meiotic sex chromosome inactivation. Curr Biol 2004; 14:2135-42.
-
(2004)
Curr Biol
, vol.14
, pp. 2135-2142
-
-
Turner, J.M.1
Aprelikova, O.2
Xu, X.3
Wang, R.4
Kim, S.5
Chandramouli, G.V.6
Barrett, J.C.7
Burgoyne, P.S.8
Deng, C.X.9
-
18
-
-
0142240342
-
BRCT repeats as phosphopeptide-binding modules involved in protein targeting
-
Manke IA, Lowery DM, Nguyen A, Yaffe MB. BRCT repeats as phosphopeptide-binding modules involved in protein targeting. Science 2003; 302:636-9.
-
(2003)
Science
, vol.302
, pp. 636-639
-
-
Manke, I.A.1
Lowery, D.M.2
Nguyen, A.3
Yaffe, M.B.4
-
19
-
-
0142147272
-
The BRCT domain is a phospho-protein binding domain
-
Yu X, Chini CC, He M, Mer G, Chen J. The BRCT domain is a phospho-protein binding domain. Science 2003; 302:639-42.
-
(2003)
Science
, vol.302
, pp. 639-642
-
-
Yu, X.1
Chini, C.C.2
He, M.3
Mer, G.4
Chen, J.5
-
20
-
-
0034804672
-
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
-
Brzovic PS, Rajagopal P, Hoyt DW, King MC, Klevit RE. Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol 2001; 8:833-7.
-
(2001)
Nat Struct Biol
, vol.8
, pp. 833-837
-
-
Brzovic, P.S.1
Rajagopal, P.2
Hoyt, D.W.3
King, M.C.4
Klevit, R.E.5
-
21
-
-
0035805582
-
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
-
Hashizume R, Fukuda M, Maeda I, Nishikawa H, Oyake D, Yabuki Y, Ogata H, Ohta T. The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem 2001; 276:14537-40.
-
(2001)
J Biol Chem
, vol.276
, pp. 14537-14540
-
-
Hashizume, R.1
Fukuda, M.2
Maeda, I.3
Nishikawa, H.4
Oyake, D.5
Yabuki, Y.6
Ogata, H.7
Ohta, T.8
-
22
-
-
0035942190
-
Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity
-
USA
-
Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM. Cancer-predisposing mutations within the RING domain of BRCA1: Loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity. Proc Natl Acad Sci USA 2001; 98:5134-9.
-
(2001)
Proc Natl Acad Sci
, vol.98
, pp. 5134-5139
-
-
Ruffner, H.1
Joazeiro, C.A.2
Hemmati, D.3
Hunter, T.4
Verma, I.M.5
-
23
-
-
0037610801
-
Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex
-
USA
-
Brzovic PS, Keeffe JR, Nishikawa H, Miyamoto K, Fox IIIrd D, Fukuda M, Ohta T, Klevit R. Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Proc Natl Acad Sci USA 2003; 100:5646-51.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 5646-5651
-
-
Brzovic, P.S.1
Keeffe, J.R.2
Nishikawa, H.3
Miyamoto, K.4
Fox III, D.5
Fukuda, M.6
Ohta, T.7
Klevit, R.8
-
24
-
-
0037122004
-
Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains
-
Mallery DL, Vandenberg CJ, Hiom K. Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains. EMBO J 2002; 21:6755-62.
-
(2002)
EMBO J
, vol.21
, pp. 6755-6762
-
-
Mallery, D.L.1
Vandenberg, C.J.2
Hiom, K.3
-
25
-
-
0042317328
-
The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin
-
Wu-Baer F, Lagrazon K, Yuan W, Baer R. The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin. J Biol Chem 2003; 278:34743-6.
-
(2003)
J Biol Chem
, vol.278
, pp. 34743-34746
-
-
Wu-Baer, F.1
Lagrazon, K.2
Yuan, W.3
Baer, R.4
-
26
-
-
1942517849
-
BRCA1: BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair
-
Morris JR, Solomon E. BRCA1: BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair. Hum Mol Genet 2004; 13:807-17.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 807-817
-
-
Morris, J.R.1
Solomon, E.2
-
27
-
-
0345276495
-
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair
-
Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R. Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair. Mol Cell 2003; 12:1087-99.
-
(2003)
Mol Cell
, vol.12
, pp. 1087-1099
-
-
Dong, Y.1
Hakimi, M.A.2
Chen, X.3
Kumaraswamy, E.4
Cooch, N.S.5
Godwin, A.K.6
Shiekhattar, R.7
-
28
-
-
0346335800
-
BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans
-
Boulton SJ, Martin JS, Polanowska J, Hill DE, Gartner A, Vidal M. BRCA1/BARD1 orthologs required for DNA repair in Caenorhabditis elegans. Curr Biol 2004; 14:33-9.
-
(2004)
Curr Biol
, vol.14
, pp. 33-39
-
-
Boulton, S.J.1
Martin, J.S.2
Polanowska, J.3
Hill, D.E.4
Gartner, A.5
Vidal, M.6
-
30
-
-
0042566182
-
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans
-
Alpi A, Pasierbek P, Gartner A, Loidl J. Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegans. Chromosoma 2003; 112:6-16.
-
(2003)
Chromosoma
, vol.112
, pp. 6-16
-
-
Alpi, A.1
Pasierbek, P.2
Gartner, A.3
Loidl, J.4
-
31
-
-
29244440434
-
Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans
-
Garcia-Muse T, Boulton SJ. Distinct modes of ATR activation after replication stress and DNA double-strand breaks in Caenorhabditis elegans. Embo J 2005; 24:4345-55.
-
(2005)
Embo J
, vol.24
, pp. 4345-4355
-
-
Garcia-Muse, T.1
Boulton, S.J.2
-
32
-
-
0033637170
-
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
-
Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT. Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress. Genes Dev 2000; 14:2989-3002.
-
(2000)
Genes Dev
, vol.14
, pp. 2989-3002
-
-
Tibbetts, R.S.1
Cortez, D.2
Brumbaugh, K.M.3
Scully, R.4
Livingston, D.5
Elledge, S.J.6
Abraham, R.T.7
-
33
-
-
0036634066
-
Seek and destroy: SCF ubiquitin ligases in mammalian cell cycle control
-
Spruck CH, Strohmaier HM. Seek and destroy: SCF ubiquitin ligases in mammalian cell cycle control. Cell Cycle 2002; 1:250-4.
-
(2002)
Cell Cycle
, vol.1
, pp. 250-254
-
-
Spruck, C.H.1
Strohmaier, H.M.2
-
34
-
-
20444428382
-
Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest
-
Somesh BP, Reid J, Liu WF, Sogaard TM, Erdjument-Bromage H, Tempst P, Svejstrup JQ. Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest. Cell 2005; 121:913-23.
-
(2005)
Cell
, vol.121
, pp. 913-923
-
-
Somesh, B.P.1
Reid, J.2
Liu, W.F.3
Sogaard, T.M.4
Erdjument-Bromage, H.5
Tempst, P.6
Svejstrup, J.Q.7
-
35
-
-
0037068455
-
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
-
Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 2002; 419:135-41.
-
(2002)
Nature
, vol.419
, pp. 135-141
-
-
Hoege, C.1
Pfander, B.2
Moldovan, G.L.3
Pyrowolakis, G.4
Jentsch, S.5
|