Kinetic and chemical mechanism of α-isopropylmalate synthase from Mycobacterium tuberculosis

Biochemistry

Volumn 45, Issue 29, 2006, Pages 8988-8999

  De Carvalho, Luiz Pedro S ^a   Blanchard, John S ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CONDENSATION; ENZYMES; HYDROLYSIS; ISOTOPES; MOLECULAR SPECTROSCOPY; REACTION KINETICS; SOLVENTS; SUBSTRATES;

DEPROTONATION; ENOLIZATION; ISOPROPYLMALATE; KETOISOVALERATE; MYCOBACTERIUM TUBERCULOSIS;

BACTERIA;

2 ISOPROPYLMALATE SYNTHASE; ACETYL COENZYME A; DEUTERIUM; ISOVALERIC ACID; LEUCINE;

ARTICLE; CATALYSIS; ENZYME KINETICS; ENZYME MECHANISM; HYDROLYSIS; ISOTOPE LABELING; METAL BINDING; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEADY STATE;

2-ISOPROPYLMALATE SYNTHASE; ACETYL COENZYME A; CHROMATOGRAPHY, GEL; DIMERIZATION; ISOTOPE LABELING; KINETICS; MYCOBACTERIUM TUBERCULOSIS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

MYCOBACTERIUM TUBERCULOSIS;

EID: 33746267476     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0606602     Document Type: Article

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