Selective inhibition of human type 1 11β-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

FEBS Letters

Volumn 441, Issue 1, 1998, Pages 25-28

  Hult, Malin ^a   Jörnvall, Hans ^a   Oppermann, Udo C T ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

11 Hydroxysteroid dehydrogenase; Glucocorticoid; Membrane protein; Short chain dehydrogenase reductase; Yeast expression

Indexed keywords

BUDESONIDE; CORTISONE; DEFLAZACORT; FUROSEMIDE; GLUCOCORTICOID; HYDROCORTISONE; HYDROXYSTEROID DEHYDROGENASE; MINERALOCORTICOID RECEPTOR; PREDNISONE; XENOBIOTIC AGENT;

ADIPOSE TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HUMAN; LIVER; MICROSOME; NONHUMAN; PRIORITY JOURNAL; YEAST;

11-BETA-HYDROXYSTEROID DEHYDROGENASES; CLONING, MOLECULAR; ENZYME INHIBITORS; ESTRADIOL CONGENERS; FLAVANONES; FLAVONOIDS; FUROSEMIDE; HUMANS; HYDROXYSTEROID DEHYDROGENASES; KINETICS; MICROSOMES; PICHIA; RECOMBINANT PROTEINS; STEROIDS; SUBSTRATE SPECIFICITY; XENOBIOTICS;

PICHIA PASTORIS;

EID: 0345004847     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(98)01515-4     Document Type: Article

References (26)

1. Beato, M., Herrlich, P. and Schuetz, G. (1995) Cell 83, 851-857.
2. Barnes, P.J. (1995) Biochem. Soc. Trans. 23, 940-945.
3. Seckl, J.R. (1997) Front. Neuroendocrinol. 18, 49-99.
4. Oppermann, U.C.T., Persson, B. and Jörnvall, H. (1997) Eur. J. Biochem. 249, 355-360.
5. Gomez-Sanchez, E.P., Cox, D., Foecking, M., Ganjam, V. and Gomez-Sanchez, C.E. (1996) Steroids 61, 110-115.
6. Jörnvall, H., Persson, B., Krook, M., Atrian, S., Gonzalez-Duarte, R., Jeffery, J. and Ghosh, D. (1995) Biochemistry 34, 6003-6013.
7. Monder, C. and White, P.C. (1993) Vitamins Hormones 47, 187-271.
8. Tannin, G.M., Agarwal, A.K., Monder, C., New, M.I. and White, P.C. (1991) J. Biol. Chem. 266, 16653-16658.
9. Voice, M., Seckl, J.R., Edwards, C.R.W. and Chapman, K.E. (1996) Biochem. J. 317, 621-625.
10. Mune, T., Rogerson, F.M., Nikkilä, H., Agarwal, A.K. and White, P.C. (1995) Nature Genet. 10, 394-399.
11. Krozowski, Z., Albiston, A.L., Obeyesekere, V.R., Andrews, R.K. and Smith, R.E. (1995) J. Steroid Biochem. Mol. Biol. 55, 457-464.
12. Cregg, J.M., Vedvick, T.S. and Raschke, W.C. (1993) BioTechnology 11, 905-910.
13. Walker, B., Connacher, A.A., Lindsay, M., Webb, D.J. and Edwards, C.R.W. (1995) J. Clin. Endocrinol. Metab. 80, 3155-3159.
14. Bujalska, I.J., Kumar, S. and Stewart, P.M. (1997) Lancet 349, 1210-1213.
15. Kotelevtsev, J., Holmes, M.C., Burchill, A., Houston, P.M., Schmoll, D., Jamieson, P., Best, R., Brown, R., Edwards, C.R.W., Seckl, J.R. and Mullins, J.J. (1997) Proc. Natl. Acad. Sci. USA 94, 14924-14929.
16. Krozowski, Z. (1996) Endocr. Res. 22, 781-790.
17. Agarwal, A.K., Tusie-Luna, M.T., Monder, C. and White, P.C. (1990) Mol. Endocrinol. 4, 1827-1832.
18. Best, R., Nelson, S.M. and Walker, B.R. (1997) J. Endocrinol. 153, 41-48.
19. Agarwal, A.K., Mune, T., Monder, C. and White, P.C. (1995) Biochim. Biophys. Acta 1248, 70-74.
20. Low, S.C., Chapman, K.E., Edwards, C.R.W. and Seckl, J.R. (1994) J. Mol. Endocrinol. 13, 167-174.
21. Oppermann, U.C.T., Filling, C., Berndt, K.D., Persson, B., Benach, J., Ladenstein, R. and Jörnvall, H. (1997) Biochemistry 36, 34-40.
22. Oelkers, W., Buchen, S., Diederich, S., Krain, J., Muhme, S. and Schöneshofer, M. (1994) J. Clin. Endocrinol. Metab. 78, 928-932.
23. Frey, F.J., Escher, G. and Frey, B.M. (1994) Steroids 59, 74-79.
24. Best, R., Nelson, S.M. and Walker, B.R. (1997) J. Endocrinol. 153, 41-48.
25. Keung, W.M. (1995) Biochem. Biophys. Res. Commun. 215, 1137-1144.
26. Zhang, Y.D., Lorenzo, B. and Reidenberg, M.M. (1994) J. Steroid Biochem. Mol. Biol. 49, 81-85.