메뉴 건너뛰기




Volumn 9, Issue 2, 2006, Pages 207-218

Correlations of disability and biologic alterations in Alzheimer brain and test of significance by a therapeutic trial in humans

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; DONEPEZIL; DRUG ADDITIVE; GLUCOSE; MALIC ACID; NEUROLEPTIC AGENT; PLACEBO; RESVERATROL; VITAMIN;

EID: 33746048749     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2006-9212     Document Type: Article
Times cited : (16)

References (71)
  • 1
    • 23044489284 scopus 로고    scopus 로고
    • Toward a remembrance of things past: Deciphering Alzheimer disease
    • D.J. Selkoe, Toward a remembrance of things past: deciphering Alzheimer disease, Harvey Led 99 (2003-2004), 23-45.
    • (2003) Harvey Led , vol.99 , pp. 23-45
    • Selkoe, D.J.1
  • 2
    • 0034512488 scopus 로고    scopus 로고
    • The mitochondrial spiral. An adequate cause of dementia in the Alzheimer's syndrome
    • J.P. Blass, The mitochondrial spiral. An adequate cause of dementia in the Alzheimer's syndrome, Ann N Y Acad Sci 924 (2000), 170-183.
    • (2000) Ann N Y Acad Sci , vol.924 , pp. 170-183
    • Blass, J.P.1
  • 4
    • 3042806534 scopus 로고    scopus 로고
    • A mitochondrial cascade hypothesis for sporadic Alzheimer's disease
    • R.H. Swerdlow and S.M. Khan, A mitochondrial cascade hypothesis for sporadic Alzheimer's disease, Med Hypotheses 63 (2004), 8-20.
    • (2004) Med Hypotheses , vol.63 , pp. 8-20
    • Swerdlow, R.H.1    Khan, S.M.2
  • 6
    • 0036727610 scopus 로고    scopus 로고
    • Anti-inflammatory agents in Alzheimer's disease
    • P.S. Aisen, Anti-inflammatory agents in Alzheimer's disease, Curr Neurol Neurosci Rep 2 (2002), 405-409.
    • (2002) Curr Neurol Neurosci Rep , vol.2 , pp. 405-409
    • Aisen, P.S.1
  • 7
    • 10044297055 scopus 로고    scopus 로고
    • Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging
    • M.T. Jensen, M.D. Mottin, J.R. Cracchiolo, R.E. Leighty and G.W. Arendash, Lifelong immunization with human beta-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging, Neuroscience 130 (2005), 667-684.
    • (2005) Neuroscience , vol.130 , pp. 667-684
    • Jensen, M.T.1    Mottin, M.D.2    Cracchiolo, J.R.3    Leighty, R.E.4    Arendash, G.W.5
  • 8
    • 1442314722 scopus 로고    scopus 로고
    • Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease
    • Epub 2003 Dec 4
    • S. Sung, Y. Yao, K. Uryu, H. Yang, V.M. Lee, J.Q. Trojanowski and D. Pratico, Early vitamin E supplementation in young but not aged mice reduces Abeta levels and amyloid deposition in a transgenic model of Alzheimer's disease, FASEB J 18 (2004), 323-325. Epub 2003 Dec 4.
    • (2004) FASEB J , vol.18 , pp. 323-325
    • Sung, S.1    Yao, Y.2    Uryu, K.3    Yang, H.4    Lee, V.M.5    Trojanowski, J.Q.6    Pratico, D.7
  • 11
  • 12
    • 0028132966 scopus 로고
    • Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia
    • W. Samuel, R.D. Terry, R. DeTeresa, N. Butters and E. Masliah, Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia, Arch Neurol 51 (1994), 772-778.
    • (1994) Arch Neurol , vol.51 , pp. 772-778
    • Samuel, W.1    Terry, R.D.2    DeTeresa, R.3    Butters, N.4    Masliah, E.5
  • 13
    • 0028965458 scopus 로고
    • P-300 in Alzheimer's disease: Relationships to dementia severity and glucose metabolism
    • B. Szieles, R. Mielke, M. Grand and W.D. Heiss, P-300 in Alzheimer's disease: Relationships to dementia severity and glucose metabolism, J Neurol Sci 130 (1995), 77-81.
    • (1995) J Neurol Sci , vol.130 , pp. 77-81
    • Szieles, B.1    Mielke, R.2    Grand, M.3    Heiss, W.D.4
  • 14
    • 0029045389 scopus 로고
    • Cognitive impairment in Alzheimer's disease correlates with ventricular width and atrophy-corrected cortical glucose metabolism
    • I. Slansky, K. Herholz, U. Pietrzyk, J. Kessler, M. Grond, R. Mielke and W.-D. Heiss, Cognitive impairment in Alzheimer's disease correlates with ventricular width and atrophy-corrected cortical glucose metabolism, Neuroradiology 37 (1995), 270-277.
    • (1995) Neuroradiology , vol.37 , pp. 270-277
    • Slansky, I.1    Herholz, K.2    Pietrzyk, U.3    Kessler, J.4    Grond, M.5    Mielke, R.6    Heiss, W.-D.7
  • 16
    • 0030567762 scopus 로고    scopus 로고
    • Altered oxidation and signal transduction systems in fibroblasts from Alzheimer patients
    • G. Gibson, R. Martins, J. Blass and S. Gandy, Altered oxidation and signal transduction systems in fibroblasts from Alzheimer patients, Life Sci 59 (1996), 477-489.
    • (1996) Life Sci , vol.59 , pp. 477-489
    • Gibson, G.1    Martins, R.2    Blass, J.3    Gandy, S.4
  • 17
    • 18244390483 scopus 로고    scopus 로고
    • Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
    • P. Bubber, V. Haroutunian, G. Fisch, J.P. Blass and G.E. Gibson, Mitochondrial abnormalities in Alzheimer brain: mechanistic implications, Ann Neurol 57 (2005), 695-703.
    • (2005) Ann Neurol , vol.57 , pp. 695-703
    • Bubber, P.1    Haroutunian, V.2    Fisch, G.3    Blass, J.P.4    Gibson, G.E.5
  • 18
    • 0026802334 scopus 로고
    • Metabolic control analysis: A survey of its theoretical and experimental development
    • D.A. Fell, Metabolic control analysis: a survey of its theoretical and experimental development, Biochem J 286(Pt 2) (1992), 313-330.
    • (1992) Biochem J , vol.286 , Issue.2 PART , pp. 313-330
    • Fell, D.A.1
  • 19
    • 0020685951 scopus 로고
    • Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain
    • S. Sorbi, E.D. Bird and J.P. Blass, Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain, Ann Neurol 13 (1983), 72-78.
    • (1983) Ann Neurol , vol.13 , pp. 72-78
    • Sorbi, S.1    Bird, E.D.2    Blass, J.P.3
  • 20
    • 0017295228 scopus 로고
    • Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia
    • W. Op den Velde and F.C. Stam, Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia, J Am Geriatr Soc 24 (1976), 12-16.
    • (1976) J Am Geriatr Soc , vol.24 , pp. 12-16
    • Op Den Velde, W.1    Stam, F.C.2
  • 21
    • 17644399528 scopus 로고    scopus 로고
    • The clinical syndrome of Alzheimer's disease: Aspects particularly relevant to clinical trials
    • R.C. Mohs, The clinical syndrome of Alzheimer's disease: aspects particularly relevant to clinical trials, Genes Brain Behav 4 (2005), 129-133.
    • (2005) Genes Brain Behav , vol.4 , pp. 129-133
    • Mohs, R.C.1
  • 22
    • 0031861864 scopus 로고    scopus 로고
    • Absence of vascular dementia in an autopsy series from a dementia clinic
    • K.A. Nolan, M.M. Lino, A.W. Seligmann and J.P. Blass, Absence of vascular dementia in an autopsy series from a dementia clinic, J Am Geriatr Soc 46 (1998), 597-604.
    • (1998) J Am Geriatr Soc , vol.46 , pp. 597-604
    • Nolan, K.A.1    Lino, M.M.2    Seligmann, A.W.3    Blass, J.P.4
  • 23
    • 0037455920 scopus 로고    scopus 로고
    • Correlation of oxidative stress and the loss of the nicotinic receptor alpha 4 subunit in the temporal cortex of patients with Alzheimer's disease
    • W.F. Yu, A. Nordberg, R. Ravid and Z.Z. Guan, Correlation of oxidative stress and the loss of the nicotinic receptor alpha 4 subunit in the temporal cortex of patients with Alzheimer's disease, Neurosci Lett 338 (2003), 13-16.
    • (2003) Neurosci Lett , vol.338 , pp. 13-16
    • Yu, W.F.1    Nordberg, A.2    Ravid, R.3    Guan, Z.Z.4
  • 24
    • 0036272650 scopus 로고    scopus 로고
    • Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
    • C.S. Casley, L. Canevari, J.M. Land, J.B. Clark and M.A. Sharpe, Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities, J Neurochem 80 (2002), 91-100.
    • (2002) J Neurochem , vol.80 , pp. 91-100
    • Casley, C.S.1    Canevari, L.2    Land, J.M.3    Clark, J.B.4    Sharpe, M.A.5
  • 26
    • 0029970342 scopus 로고    scopus 로고
    • Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E
    • E.M. Reiman, R.J. Caselli, L.S. Yun, K. Chen, D. Bandy, S. Minoshima, S.N. Thibodeau and D. Osborne, Preclinical evidence of Alzheimer's disease in persons homozygous for the epsilon 4 allele for apolipoprotein E, N Engl J Med 334 (1996), 752-758.
    • (1996) N Engl J Med , vol.334 , pp. 752-758
    • Reiman, E.M.1    Caselli, R.J.2    Yun, L.S.3    Chen, K.4    Bandy, D.5    Minoshima, S.6    Thibodeau, S.N.7    Osborne, D.8
  • 27
    • 0035070084 scopus 로고    scopus 로고
    • Expression and distribution of beta amyloid precursor protein and beta amyloid peptide in reactive astrocytes after transient middle cerebral artery occlusion
    • T. Nihashi, S. Inao, Y. Kajita, T. Kawai, T. Sugimoto, M. Niwa, R. Kabeya, N. Hata, S. Hayashi and J. Yoshida, Expression and distribution of beta amyloid precursor protein and beta amyloid peptide in reactive astrocytes after transient middle cerebral artery occlusion, Acta Neurochir (Wien) 143 (2001), 287-295.
    • (2001) Acta Neurochir (Wien) , vol.143 , pp. 287-295
    • Nihashi, T.1    Inao, S.2    Kajita, Y.3    Kawai, T.4    Sugimoto, T.5    Niwa, M.6    Kabeya, R.7    Hata, N.8    Hayashi, S.9    Yoshida, J.10
  • 28
    • 0025183062 scopus 로고
    • Induction of Alzheimer antigens by an uncoupler of oxidative phosphorylation
    • J.P. Blass, A.C. Baker, L. Ko and R.S. Black, Induction of Alzheimer antigens by an uncoupler of oxidative phosphorylation, Arch Neurol 47 (1990), 864-869.
    • (1990) Arch Neurol , vol.47 , pp. 864-869
    • Blass, J.P.1    Baker, A.C.2    Ko, L.3    Black, R.S.4
  • 29
    • 0026659777 scopus 로고
    • Glucose deprivation elicits neurofibrillary tangle-like antigenic changes in hippocampal neurons: Prevention by NGF and bFGF
    • B. Cheng and M.P. Mattson, Glucose deprivation elicits neurofibrillary tangle-like antigenic changes in hippocampal neurons: prevention by NGF and bFGF, Exp Neurol 117 (1992), 114-123.
    • (1992) Exp Neurol , vol.117 , pp. 114-123
    • Cheng, B.1    Mattson, M.P.2
  • 31
    • 1842734649 scopus 로고    scopus 로고
    • Modulation of memory by insulin and glucose: Neuropsychological observations in Alzheimer's disease
    • G.S. Watson and S. Craft, Modulation of memory by insulin and glucose: neuropsychological observations in Alzheimer's disease, Eur J Pharmacol 490 (2004), 97-113.
    • (2004) Eur J Pharmacol , vol.490 , pp. 97-113
    • Watson, G.S.1    Craft, S.2
  • 32
    • 15244351255 scopus 로고    scopus 로고
    • Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - Is this type 3 diabetes?
    • Feb.
    • E. Steen, B.M. Terry, E.J. Rivera, J.L. Cannon, T.R. Neely, R. Tavares, X.J. Xu, J.R. Wands and S.M. de la Monte, Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease - is this type 3 diabetes? J Alzheimers Dis 7(1) (Feb. 2005), 63-80.
    • (2005) J Alzheimers Dis , vol.7 , Issue.1 , pp. 63-80
    • Steen, E.1    Terry, B.M.2    Rivera, E.J.3    Cannon, J.L.4    Neely, T.R.5    Tavares, R.6    Xu, X.J.7    Wands, J.R.8    De La Monte, S.M.9
  • 33
    • 0035117627 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals
    • C.D. Lynch, D. Lyons, A. Khan, S.A. Bennett and W.E. Sonntag, Insulin-like growth factor-1 selectively increases glucose utilization in brains of aged animals, Endocrinology 142 (2001), 506-509.
    • (2001) Endocrinology , vol.142 , pp. 506-509
    • Lynch, C.D.1    Lyons, D.2    Khan, A.3    Bennett, S.A.4    Sonntag, W.E.5
  • 34
    • 0036591850 scopus 로고    scopus 로고
    • Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease
    • G.E. Gibson, Interactions of oxidative stress with cellular calcium dynamics and glucose metabolism in Alzheimer's disease, Free Radic Biol Med 32 (2002), 1061-1070.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1061-1070
    • Gibson, G.E.1
  • 35
    • 0034103586 scopus 로고    scopus 로고
    • Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise
    • J.P. Blass, R.K. Sheu and G.E. Gibson, Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise, Ann N Y Acad Sci 903 (2000), 204-221.
    • (2000) Ann N Y Acad Sci , vol.903 , pp. 204-221
    • Blass, J.P.1    Sheu, R.K.2    Gibson, G.E.3
  • 36
    • 4544306972 scopus 로고    scopus 로고
    • Dietary factors and Alzheimer's disease
    • J.A. Luchsinger and R. Mayeux, Dietary factors and Alzheimer's disease, Lancet Neurol 3 (2004), 579-587.
    • (2004) Lancet Neurol , vol.3 , pp. 579-587
    • Luchsinger, J.A.1    Mayeux, R.2
  • 37
    • 85039323428 scopus 로고    scopus 로고
    • Effects of free radical quenchers in foods: Chemistry and fantasy
    • and, in preparation
    • J.P. Blass, Effects of free radical quenchers in foods: Chemistry and fantasy, J Neurochem 94(75) (2005), and, in preparation.
    • (2005) J Neurochem , vol.94 , Issue.75
    • Blass, J.P.1
  • 38
    • 28844462038 scopus 로고    scopus 로고
    • A review of antioxidants and Alzheimer's disease
    • B. Frank and S. Gupta, A review of antioxidants and Alzheimer's disease, Ann Clin Psychiatry 17 (2005), 269-286.
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 269-286
    • Frank, B.1    Gupta, S.2
  • 39
    • 28544452252 scopus 로고    scopus 로고
    • Vitamin e supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract: Part 2
    • Epub 2005 Nov 15
    • D.Q. Pham and R. Plakogiannis, Vitamin e supplementation in Alzheimer's disease, Parkinson's disease, tardive dyskinesia, and cataract: part 2, Ann Pharmacother 39 (2005), 2065-2071. Epub 2005 Nov 15.
    • (2005) Ann Pharmacother , vol.39 , pp. 2065-2071
    • Pham, D.Q.1    Plakogiannis, R.2
  • 41
    • 0026061893 scopus 로고
    • Measurement of amyloid peptide precursor of Alzheimer disease in human blood by double antibody immunoradiometric assay
    • W.M. Pardridge, J.L. Buciak, J. Yang, B.L. Miller and H.V. Vinters, Measurement of amyloid peptide precursor of Alzheimer disease in human blood by double antibody immunoradiometric assay, Alzheimer Dis Assoc Disord 5 (1991), 12-24.
    • (1991) Alzheimer Dis Assoc Disord , vol.5 , pp. 12-24
    • Pardridge, W.M.1    Buciak, J.L.2    Yang, J.3    Miller, B.L.4    Vinters, H.V.5
  • 42
    • 20144387251 scopus 로고    scopus 로고
    • Decreased serum amyloid beta(1-42) autoantibody levels in Alzheimer's disease, determined by a newly developed immuno-precipitation assay with radio labeled amyloid beta(1-42) peptide
    • S. Brettschneider, N.G. Morgenthaler, S.J. Teipel, C. Fischer-Schulz, K. Burger, R. Dodel, Y. Du, H.J. Moller, A. Bergmann and H. Hampel, Decreased serum amyloid beta(1-42) autoantibody levels in Alzheimer's disease, determined by a newly developed immuno-precipitation assay with radio labeled amyloid beta(1-42) peptide, Biol Psychiatry 57 (2005), 813-816.
    • (2005) Biol Psychiatry , vol.57 , pp. 813-816
    • Brettschneider, S.1    Morgenthaler, N.G.2    Teipel, S.J.3    Fischer-Schulz, C.4    Burger, K.5    Dodel, R.6    Du, Y.7    Moller, H.J.8    Bergmann, A.9    Hampel, H.10
  • 48
    • 0029877684 scopus 로고    scopus 로고
    • Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia
    • C. Bancher, K. Jellinger, H. Lassmann, P. Fischer and F. Leblhuber, Correlations between mental state and quantitative neuropathology in the Vienna Longitudinal Study on Dementia, Eur Arch Psychiatry Clin Neurosci 246 (1996), 137-146.
    • (1996) Eur Arch Psychiatry Clin Neurosci , vol.246 , pp. 137-146
    • Bancher, C.1    Jellinger, K.2    Lassmann, H.3    Fischer, P.4    Leblhuber, F.5
  • 49
    • 0034535535 scopus 로고    scopus 로고
    • Cell death or synaptic loss in Alzheimer disease
    • R.D. Terry, Cell death or synaptic loss in Alzheimer disease, J Neuropathol Exp Neurol 59 (2000), 1118-1119.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 1118-1119
    • Terry, R.D.1
  • 50
    • 0019494341 scopus 로고
    • Some morphometric aspects of the brain in senile dementia of the Alzheimer type
    • R.D. Terry, A. Peck, R. DeTeresa, R. Schechter and D.S. Horoupian, Some morphometric aspects of the brain in senile dementia of the Alzheimer type, Ann Neurol 10 (1981), 184-192.
    • (1981) Ann Neurol , vol.10 , pp. 184-192
    • Terry, R.D.1    Peck, A.2    DeTeresa, R.3    Schechter, R.4    Horoupian, D.S.5
  • 53
    • 20444429015 scopus 로고    scopus 로고
    • Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia
    • C. Zarow, H.V. Vinters, W.G. Ellis, M.W. Weiner, D. Mungas, L. White and H.C. Chui, Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia, Ann Neurol 57 (2005), 896-903.
    • (2005) Ann Neurol , vol.57 , pp. 896-903
    • Zarow, C.1    Vinters, H.V.2    Ellis, W.G.3    Weiner, M.W.4    Mungas, D.5    White, L.6    Chui, H.C.7
  • 54
    • 0025987048 scopus 로고
    • Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
    • R.D. Terry, E. Masliah, D.P. Salmon, N. Butters, R. DeTeresa, R. Hill, L.A. Hanson and R. Katzman, Physical basis of cognitive alterations in Alzheimer's disease: Synapse loss is the major correlate of cognitive impairment, Ann Neurol 30 (1991), 572-580.
    • (1991) Ann Neurol , vol.30 , pp. 572-580
    • Terry, R.D.1    Masliah, E.2    Salmon, D.P.3    Butters, N.4    DeTeresa, R.5    Hill, R.6    Hanson, L.A.7    Katzman, R.8
  • 55
    • 0029078972 scopus 로고
    • Correlations of synaptic and pathological markers with cognition of the elderly
    • D.W. Dickson, H.A. Crystal, C. Bevona, W. Honer, I. Vincent and P. Davies, Correlations of synaptic and pathological markers with cognition of the elderly, Neurobiol Aging 16 (1995), 285-298; discussion 298-304.
    • (1995) Neurobiol Aging , vol.16 , pp. 285-298
    • Dickson, D.W.1    Crystal, H.A.2    Bevona, C.3    Honer, W.4    Vincent, I.5    Davies, P.6
  • 57
    • 0033809884 scopus 로고    scopus 로고
    • Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease
    • E.J. Mufson, S.Y. Ma, E.J. Cochran, D.A. Bennett, L.A. Beckett, S. Jaffar, H.U. Saragovi and J.H. Kordower, Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease, J Comp Neurol 427 (2000), 19-30.
    • (2000) J Comp Neurol , vol.427 , pp. 19-30
    • Mufson, E.J.1    Ma, S.Y.2    Cochran, E.J.3    Bennett, D.A.4    Beckett, L.A.5    Jaffar, S.6    Saragovi, H.U.7    Kordower, J.H.8
  • 58
    • 0034649440 scopus 로고    scopus 로고
    • The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease
    • P. Tiraboschi, L.A. Hansen, M. Alford, E. Masliah, L.J. Thal and J. Corey-Bloom, The decline in synapses and cholinergic activity is asynchronous in Alzheimer's disease, Neurology (2000), 1278-1285.
    • (2000) Neurology , pp. 1278-1285
    • Tiraboschi, P.1    Hansen, L.A.2    Alford, M.3    Masliah, E.4    Thal, L.J.5    Corey-Bloom, J.6
  • 61
    • 25144495076 scopus 로고    scopus 로고
    • Modification of endoplasmic reticulum Ca(2+) stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease
    • H.M. Huang, H.L. Chen, H. Xu and G.E. Gibson, Modification of endoplasmic reticulum Ca(2+) stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease, Free Radic Biol Med 39 (2005), 979-989.
    • (2005) Free Radic Biol Med , vol.39 , pp. 979-989
    • Huang, H.M.1    Chen, H.L.2    Xu, H.3    Gibson, G.E.4
  • 62
    • 0018172378 scopus 로고
    • Alterations in acetylcholine synthesis and cyclic nucleotides in mild cerebral hypoxia
    • G.E. Gibson, M. Shimada and J.P. Blass, Alterations in acetylcholine synthesis and cyclic nucleotides in mild cerebral hypoxia, J Neurochem 31 (1978), 757-760.
    • (1978) J Neurochem , vol.31 , pp. 757-760
    • Gibson, G.E.1    Shimada, M.2    Blass, J.P.3
  • 63
    • 0021188983 scopus 로고
    • Selective alteration of neurotransmitter release by low oxygen in vitro
    • J.A. Hirsch and G.E. Gibson, Selective alteration of neurotransmitter release by low oxygen in vitro, Neurochem Res 9 (1984), 1039-1049.
    • (1984) Neurochem Res , vol.9 , pp. 1039-1049
    • Hirsch, J.A.1    Gibson, G.E.2
  • 64
    • 33644835667 scopus 로고    scopus 로고
    • Status epilepticus and brain damage: Pathology and pathophysiology
    • G.B. Young, Status epilepticus and brain damage: pathology and pathophysiology, Adv Neurol 97 (2006), 217-220.
    • (2006) Adv Neurol , vol.97 , pp. 217-220
    • Young, G.B.1
  • 66
    • 0036592758 scopus 로고    scopus 로고
    • The role of the metabolic lesion in Alzheimer's disease
    • J.P. Blass, G.E. Gibson and S. Hoyer, The role of the metabolic lesion in Alzheimer's disease, J Alzheimers Dis 4 (2002), 225-232.
    • (2002) J Alzheimers Dis , vol.4 , pp. 225-232
    • Blass, J.P.1    Gibson, G.E.2    Hoyer, S.3
  • 67
    • 0035577767 scopus 로고    scopus 로고
    • Brain metabolism and brain disease: Is metabolic deficiency the proximate cause of Alzheimer dementia?
    • J.P. Blass, Brain metabolism and brain disease: is metabolic deficiency the proximate cause of Alzheimer dementia? J Neurosci Res 66 (2001), 851-856.
    • (2001) J Neurosci Res , vol.66 , pp. 851-856
    • Blass, J.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.