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Volumn 45, Issue 2, 2006, Pages 119-134

New tendencies in the construction of subunit vaccines;Nowe tendencje w konstrukcji szczepionek podjednostkowych

Author keywords

Adjuvant; Antigen; Probiotics; Subunit vaccines

Indexed keywords

SUBUNIT VACCINE;

EID: 33745934268     PISSN: 00794252     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (2)

References (100)
  • 1
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S., Hemmi H.: Recognition of pathogen-associated molecular patterns by TLR family. Immunol. Lett. 85, 85-95 (2003)
    • (2003) Immunol. Lett. , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 2
  • 3
    • 0031935290 scopus 로고    scopus 로고
    • Efficacy of a food plant-based oral cholera toxin B subunit vaccine
    • Arakawa T., Chong D.K., Langridge W.H.: Efficacy of a food plant-based oral cholera toxin B subunit vaccine. Nat. Biotechnol. 16, 292-297 (1998)
    • (1998) Nat. Biotechnol. , vol.16 , pp. 292-297
    • Arakawa, T.1    Chong, D.K.2    Langridge, W.H.3
  • 4
    • 0028819184 scopus 로고
    • Safety and immunogenicity of a prototype oral whole-cell killed Campylobacter vaccine administered with a mucosal adjuvant in non-human primates
    • Baqar S., Bourgeois A.L., Schultheiss P.J., Walker R.I., Rollins D.M., Haberberger R.L., Pavlovskis O.R.: Safety and immunogenicity of a prototype oral whole-cell killed Campylobacter vaccine administered with a mucosal adjuvant in non-human primates. Vaccine, 13, 22-28 (1995)
    • (1995) Vaccine , vol.13 , pp. 22-28
    • Baqar, S.1    Bourgeois, A.L.2    Schultheiss, P.J.3    Walker, R.I.4    Rollins, D.M.5    Haberberger, R.L.6    Pavlovskis, O.R.7
  • 6
    • 9144244172 scopus 로고    scopus 로고
    • Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica
    • Bohn E., Autenrieth I.B. i wsp.: Gene expression patterns of epithelial cells modulated by pathogenicity factors of Yersinia enterocolitica. Cell Microbiol. 6, 129-141 (2004)
    • (2004) Cell Microbiol. , vol.6 , pp. 129-141
    • Bohn, E.1    Autenrieth, I.B.2
  • 8
    • 0033081332 scopus 로고    scopus 로고
    • Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor b1 and b2 chain expression
    • Braun M.C., He J., Wu C.Y., Kelsall B.L.: Cholera toxin suppresses interleukin (IL)-12 production and IL-12 receptor b1 and b2 chain expression. J. Exp. Med. 189, 541-552 (1999)
    • (1999) J. Exp. Med. , vol.189 , pp. 541-552
    • Braun, M.C.1    He, J.2    Wu, C.Y.3    Kelsall, B.L.4
  • 9
    • 0034212719 scopus 로고    scopus 로고
    • Antibody responses to Yersinia pestis F1-antigen expressed in Salmonella typhimurium aroA from in vivo-inducible promoters
    • Bullifent H.L., Griffin K.F., Jones S.M., Yates A., Harrington L., Titball R.W.: Antibody responses to Yersinia pestis F1-antigen expressed in Salmonella typhimurium aroA from in vivo-inducible promoters. Vaccine, 18, 2668-2676 (2000)
    • (2000) Vaccine , vol.18 , pp. 2668-2676
    • Bullifent, H.L.1    Griffin, K.F.2    Jones, S.M.3    Yates, A.4    Harrington, L.5    Titball, R.W.6
  • 10
    • 2542466966 scopus 로고    scopus 로고
    • Innate immune recognition of microbes through Nod1 and Nod2: Implications for disease
    • Carneiro L.A., Travassos L.H., Philpott D.J.: Innate immune recognition of microbes through Nod1 and Nod2: implications for disease. Microbes Infect. 6, 609-616 (2004)
    • (2004) Microbes Infect. , vol.6 , pp. 609-616
    • Carneiro, L.A.1    Travassos, L.H.2    Philpott, D.J.3
  • 11
    • 0003311308 scopus 로고    scopus 로고
    • Attenuated Salmonella as a live vector for expression of foreign antigens. (Expressing bacterial antigens)
    • red. M.M. Levine, G.C. Woodrow, J.B. Kaper, G.S. Cobon, Marcel Dekker, Inc. New York, Basel and Honk Kong
    • Chatfield S., Dougan G., Attenuated Salmonella as a live vector for expression of foreign antigens. (Expressing bacterial antigens). (w) New Generation Vaccines, red. M.M. Levine, G.C. Woodrow, J.B. Kaper, G.S. Cobon, Marcel Dekker, Inc. New York, Basel and Honk Kong, 1997, s. 331-341.
    • (1997) New Generation Vaccines , pp. 331-341
    • Chatfield, S.1    Dougan, G.2
  • 12
    • 14744302999 scopus 로고
    • Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: Development of a single-dose oral tetanus vaccine
    • Chatfield S.N., Charles I.G., Makoff A.J., Oxer M.D., Dougan G., Pickard D., Slater D., Fairweather N.F.: Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: development of a single-dose oral tetanus vaccine. Biotechnology, 10, 888-892 (1992)
    • (1992) Biotechnology , vol.10 , pp. 888-892
    • Chatfield, S.N.1    Charles, I.G.2    Makoff, A.J.3    Oxer, M.D.4    Dougan, G.5    Pickard, D.6    Slater, D.7    Fairweather, N.F.8
  • 13
    • 0034601106 scopus 로고    scopus 로고
    • Recent advances in mucosal vaccine development
    • Chen H.: Recent advances in mucosal vaccine development. J. Control. Release. 67, 117-128 (2000)
    • (2000) J. Control. Release. , vol.67 , pp. 117-128
    • Chen, H.1
  • 14
    • 0036774095 scopus 로고    scopus 로고
    • A functional antigen in a practical crop: LT-B producing maize protects mice against Escherichia coli heat labile enterotoxin (LT) and cholera toxin (CT)
    • Chikwamba R., Cunnick J., Hathaway D., McMurray J., Mason H., Wang K.: A functional antigen in a practical crop: LT-B producing maize protects mice against Escherichia coli heat labile enterotoxin (LT) and cholera toxin (CT). Transgenic Res. 11, 479-493 (2002)
    • (2002) Transgenic Res. , vol.11 , pp. 479-493
    • Chikwamba, R.1    Cunnick, J.2    Hathaway, D.3    McMurray, J.4    Mason, H.5    Wang, K.6
  • 15
    • 0030613651 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity
    • Chu R.S., Targoni O., Krieg A.M., Lehmann P.V., Harding C.V.: CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity. J. Exp. Med. 186, 1623-1631 (1997)
    • (1997) J. Exp. Med. , vol.186 , pp. 1623-1631
    • Chu, R.S.1    Targoni, O.2    Krieg, A.M.3    Lehmann, P.V.4    Harding, C.V.5
  • 16
    • 0031042884 scopus 로고    scopus 로고
    • Adjuvants - A classification and review of their modes of action
    • Cox J.C., Coulter A.R.: Adjuvants - a classification and review of their modes of action. Vaccine, 15, 248-256 (1997)
    • (1997) Vaccine , vol.15 , pp. 248-256
    • Cox, J.C.1    Coulter, A.R.2
  • 17
    • 33745956427 scopus 로고    scopus 로고
    • Oral immunisation by transgenic plants. World Patent Application 1990 WO 90/02484
    • Curtiss R.I., Cardineau C.A.: Oral immunisation by transgenic plants. World Patent Application 1990 WO 90/02484].
    • Curtiss, R.I.1    Cardineau, C.A.2
  • 18
    • 0024513781 scopus 로고
    • Recombinant avirulent Salmonella vaccine strains with stable maintenance and high level expression of cloned genes in vivo
    • Curtiss R., 3rd, Nakayama K., Kelly S.M.: Recombinant avirulent Salmonella vaccine strains with stable maintenance and high level expression of cloned genes in vivo. Immunol. Invest. 18, 583-596 (1989)
    • (1989) Immunol. Invest. , vol.18 , pp. 583-596
    • Curtiss III, R.1    Nakayama, K.2    Kelly, S.M.3
  • 19
    • 0035979785 scopus 로고    scopus 로고
    • Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts
    • Daniell H., Lee S.B., Panchal T., Wiebe P.O.: Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts. J. Mol. Biol. 311, 1001-1009 (2001)
    • (2001) J. Mol. Biol. , vol.311 , pp. 1001-1009
    • Daniell, H.1    Lee, S.B.2    Panchal, T.3    Wiebe, P.O.4
  • 21
    • 0031964257 scopus 로고    scopus 로고
    • CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen
    • Davis H.L., Weeratna R., Waldschmidt T.J., Tygrett L., Schorr J., Krieg A.M., Weeranta R.: CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen. J. Immunol. 160, 870-876 (1998)
    • (1998) J. Immunol. , vol.160 , pp. 870-876
    • Davis, H.L.1    Weeratna, R.2    Waldschmidt, T.J.3    Tygrett, L.4    Schorr, J.5    Krieg, A.M.6    Weeranta, R.7
  • 22
    • 0031919480 scopus 로고    scopus 로고
    • Genetically engineered vaccines: An overview
    • Dertzbaugh M.T.: Genetically engineered vaccines: an overview. Plasmid, 39, 100-113 (1998)
    • (1998) Plasmid , vol.39 , pp. 100-113
    • Dertzbaugh, M.T.1
  • 23
    • 0242323599 scopus 로고    scopus 로고
    • Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs
    • Dittmer U., Olbrich A.R.: Treatment of infectious diseases with immunostimulatory oligodeoxynucleotides containing CpG motifs. Curr. Opin. Microbiol. 6, 472-477 (2003)
    • (2003) Curr. Opin. Microbiol. , vol.6 , pp. 472-477
    • Dittmer, U.1    Olbrich, A.R.2
  • 24
    • 0030940814 scopus 로고    scopus 로고
    • Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin
    • Douce G., Fontana M., Pizza M., Rappuoli R., Dougan G.: Intranasal immunogenicity and adjuvanticity of site-directed mutant derivatives of cholera toxin. Infect. Immun. 65, 2821-2828 (1997)
    • (1997) Infect. Immun. , vol.65 , pp. 2821-2828
    • Douce, G.1    Fontana, M.2    Pizza, M.3    Rappuoli, R.4    Dougan, G.5
  • 25
    • 0031802314 scopus 로고    scopus 로고
    • Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli
    • Douce G., Giuliani M.M., Giannelli V., Pizza M.G., Rappuoli R., Dougan G.: Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli. Vaccine, 16, 1065-1073 (1998)
    • (1998) Vaccine , vol.16 , pp. 1065-1073
    • Douce, G.1    Giuliani, M.M.2    Giannelli, V.3    Pizza, M.G.4    Rappuoli, R.5    Dougan, G.6
  • 27
    • 0035316823 scopus 로고    scopus 로고
    • Bovine rotavirus nonstructural protein 4 produced by Lactococcus lactis is antigenic and immunogenic
    • Enouf V., Langella P., Commissaire J., Cohen J., Corthier G.: Bovine rotavirus nonstructural protein 4 produced by Lactococcus lactis is antigenic and immunogenic. Appl. Environ. Microbiol. 67, 1423-1428 (2001)
    • (2001) Appl. Environ. Microbiol. , vol.67 , pp. 1423-1428
    • Enouf, V.1    Langella, P.2    Commissaire, J.3    Cohen, J.4    Corthier, G.5
  • 28
    • 0028982874 scopus 로고
    • Expression of LacZ from the htrA, nirB and groE promoters in a Salmonella vaccine strain: Influence of growth in mammalian cells
    • Everest P., Frankel G., Li J., Lund P., Chatfield S., Dougan G.: Expression of LacZ from the htrA, nirB and groE promoters in a Salmonella vaccine strain: influence of growth in mammalian cells. FEMS Microbiol. Lett. 126, 97-101 (1995)
    • (1995) FEMS Microbiol. Lett. , vol.126 , pp. 97-101
    • Everest, P.1    Frankel, G.2    Li, J.3    Lund, P.4    Chatfield, S.5    Dougan, G.6
  • 29
    • 0032699918 scopus 로고    scopus 로고
    • Optimization of plasmid maintenance in the attenuated live vector vaccine strain Salmonella typhi CVD 908-htrA
    • Galen J.E., Nair J., Wang J.Y., Wasserman S.S., Tanner M.K., Sztein M.B., Levine M.M.: Optimization of plasmid maintenance in the attenuated live vector vaccine strain Salmonella typhi CVD 908-htrA. Infect. Immun. 67, 6424-6433 (1999)
    • (1999) Infect. Immun. , vol.67 , pp. 6424-6433
    • Galen, J.E.1    Nair, J.2    Wang, J.Y.3    Wasserman, S.S.4    Tanner, M.K.5    Sztein, M.B.6    Levine, M.M.7
  • 30
    • 0035284751 scopus 로고    scopus 로고
    • Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract
    • Gallichan W.S., Woolstencroft R.N., Guarasci T., McCluskie M.J., Davis H.L., Rosenthal K.L.: Intranasal immunization with CpG oligodeoxynucleotides as an adjuvant dramatically increases IgA and protection against herpes simplex virus-2 in the genital tract. J. Immunol. 166, 3451-3457 (2001)
    • (2001) J. Immunol. , vol.166 , pp. 3451-3457
    • Gallichan, W.S.1    Woolstencroft, R.N.2    Guarasci, T.3    McCluskie, M.J.4    Davis, H.L.5    Rosenthal, K.L.6
  • 31
    • 0016822485 scopus 로고
    • Isolation and characterization of GalE mutant Ty 21a of Salmonella typhi: A candidate strain for a live, oral typhoid vaccine
    • Germanier R., Fuer E.: Isolation and characterization of GalE mutant Ty 21a of Salmonella typhi: a candidate strain for a live, oral typhoid vaccine. J. Infect. Dis. 131, 553-558 (1975)
    • (1975) J. Infect. Dis. , vol.131 , pp. 553-558
    • Germanier, R.1    Fuer, E.2
  • 32
    • 0030728943 scopus 로고    scopus 로고
    • Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
    • Ghiara P., Del Giudice G. i wsp.: Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection. Infect. Immun. 65, 4996-5002 (1997)
    • (1997) Infect. Immun. , vol.65 , pp. 4996-5002
    • Ghiara, P.1    Del Giudice, G.2
  • 33
    • 0344564184 scopus 로고    scopus 로고
    • Phase 1 evaluation of intranasal virosomal influenza vaccine with and without Escherichia coli heat-labile toxin in adult volunteers
    • Gluck U., Gebbers J.O., Gluck R.: Phase 1 evaluation of intranasal virosomal influenza vaccine with and without Escherichia coli heat-labile toxin in adult volunteers. J. Virol. 73, 7780-7786 (1999)
    • (1999) J. Virol. , vol.73 , pp. 7780-7786
    • Gluck, U.1    Gebbers, J.O.2    Gluck, R.3
  • 34
    • 0032078757 scopus 로고    scopus 로고
    • Immunogenicity of a Salmonella typhi CVD 908 candidate vaccine strain expressing the major surface protein gp63 of Leishmania mexicana mexicana
    • Gonzalez C.R., Noriega F.R., Huerta S., Santiago A., Vega M., Paniagua J., Ortiz-Navarrete V., Isibasi A., Levine M.M.: Immunogenicity of a Salmonella typhi CVD 908 candidate vaccine strain expressing the major surface protein gp63 of Leishmania mexicana mexicana. Vaccine, 16, 1043-1052 (1998)
    • (1998) Vaccine , vol.16 , pp. 1043-1052
    • Gonzalez, C.R.1    Noriega, F.R.2    Huerta, S.3    Santiago, A.4    Vega, M.5    Paniagua, J.6    Ortiz-Navarrete, V.7    Isibasi, A.8    Levine, M.M.9
  • 35
    • 0037055969 scopus 로고    scopus 로고
    • Protection against tetanus toxin after intragastric administration of two recombinant lactic acid bacteria: Impact of strain viability and in vivo persistence
    • Grangette C., Muller-Alouf H., Geoffroy M., Goudercourt D., Turneer M., Mercenier A.: Protection against tetanus toxin after intragastric administration of two recombinant lactic acid bacteria: impact of strain viability and in vivo persistence. Vaccine, 20, 3304-3309 (2002)
    • (2002) Vaccine , vol.20 , pp. 3304-3309
    • Grangette, C.1    Muller-Alouf, H.2    Geoffroy, M.3    Goudercourt, D.4    Turneer, M.5    Mercenier, A.6
  • 36
    • 0035118294 scopus 로고    scopus 로고
    • Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum
    • Grangette C., Muller-Alouf H., Goudercourt D., Geoffroy M.C., Turneer M., Mercenier A.: Mucosal immune responses and protection against tetanus toxin after intranasal immunization with recombinant Lactobacillus plantarum. Infect. Immun. 69, 1547-1553 (2001)
    • (2001) Infect. Immun. , vol.69 , pp. 1547-1553
    • Grangette, C.1    Muller-Alouf, H.2    Goudercourt, D.3    Geoffroy, M.C.4    Turneer, M.5    Mercenier, A.6
  • 37
    • 0035815512 scopus 로고    scopus 로고
    • Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity
    • Haan L., Verweij W.R., Holtrop M., Brands R., van Scharrenburg G.J., Palache A.M., Agsteribbe E., Wilschut J.: Nasal or intramuscular immunization of mice with influenza subunit antigen and the B subunit of Escherichia coli heat-labile toxin induces IgA- or IgG-mediated protective mucosal immunity. Vaccine, 19, 2898-2907 (2001)
    • (2001) Vaccine , vol.19 , pp. 2898-2907
    • Haan, L.1    Verweij, W.R.2    Holtrop, M.3    Brands, R.4    Van Scharrenburg, G.J.5    Palache, A.M.6    Agsteribbe, E.7    Wilschut, J.8
  • 38
    • 0031961222 scopus 로고    scopus 로고
    • A Salmonella typhimurium strain genetically engineered to secrete effectively a bioactive human interleukin (ML)-6 via the Escherichia coli hemolysin secretion apparatus
    • Hahn H.P., Hess C., Gabelsberger J., Domdey H., von Specht B.U.: A Salmonella typhimurium strain genetically engineered to secrete effectively a bioactive human interleukin (ML)-6 via the Escherichia coli hemolysin secretion apparatus. FEMS Immunol. Med. Microbiol. 20, 111-119 (1998)
    • (1998) FEMS Immunol. Med. Microbiol. , vol.20 , pp. 111-119
    • Hahn, H.P.1    Hess, C.2    Gabelsberger, J.3    Domdey, H.4    Von Specht, B.U.5
  • 39
    • 0034787922 scopus 로고    scopus 로고
    • Playing Dr Jekyll and Mr Hyde: Combined mechanisms of phase variation in bacteria
    • Hallet B.: Playing Dr Jekyll and Mr Hyde: combined mechanisms of phase variation in bacteria. Curr. Opin. Microbiol. 4, 570-581 (2001)
    • (2001) Curr. Opin. Microbiol. , vol.4 , pp. 570-581
    • Hallet, B.1
  • 40
    • 0034237172 scopus 로고    scopus 로고
    • Intramuscular immunization with genetically inactivated (ghosts) Actinobacillus pleuropneumoniae serotype 9 protects pigs against homologous aerosol challenge and prevents carrier state
    • Hensel A., Huter V., Katinger A., Raza P., Strnistschie C., Roesler U., Brand E., Lubitz W.: Intramuscular immunization with genetically inactivated (ghosts) Actinobacillus pleuropneumoniae serotype 9 protects pigs against homologous aerosol challenge and prevents carrier state. Vaccine, 18, 2945-2955 (2000)
    • (2000) Vaccine , vol.18 , pp. 2945-2955
    • Hensel, A.1    Huter, V.2    Katinger, A.3    Raza, P.4    Strnistschie, C.5    Roesler, U.6    Brand, E.7    Lubitz, W.8
  • 41
    • 0034116281 scopus 로고    scopus 로고
    • Immunostimulatory sequence oligodeoxynucleotide: A novel mucosal adjuvant
    • Horner A.A., Raz E.: Immunostimulatory sequence oligodeoxynucleotide: A novel mucosal adjuvant. Clin. Immunol. 95, S19-29 (2000)
    • (2000) Clin. Immunol. , vol.95
    • Horner, A.A.1    Raz, E.2
  • 42
    • 0034730695 scopus 로고    scopus 로고
    • Improved protection against lung colonization by Actinobacillus pleuropneumoniae ghosts: Characterization of a genetically inactivated vaccine
    • Huter V., Hensel A., Brand E., Lubitz W.: Improved protection against lung colonization by Actinobacillus pleuropneumoniae ghosts: characterization of a genetically inactivated vaccine. J. Biotechnol. 83, 161-172 (2000)
    • (2000) J. Biotechnol. , vol.83 , pp. 161-172
    • Huter, V.1    Hensel, A.2    Brand, E.3    Lubitz, W.4
  • 43
    • 0034662962 scopus 로고    scopus 로고
    • Interaction of pseudomonas aerugmosa with epithelial cells: Identification of differentially regulated genes by expression microarray analysis of human cDNAs
    • Ichikawa J.K., Norris A., Bangera M.G., Geiss G.K., van't Wout A.B., Bumgarner R.E., Lory S.: Interaction of pseudomonas aerugmosa with epithelial cells: identification of differentially regulated genes by expression microarray analysis of human cDNAs. Proc. Natl. Acad. Sci. USA, 97, 9659-9664 (2000)
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 9659-9664
    • Ichikawa, J.K.1    Norris, A.2    Bangera, M.G.3    Geiss, G.K.4    Van't Wout, A.B.5    Bumgarner, R.E.6    Lory, S.7
  • 44
    • 0037992526 scopus 로고    scopus 로고
    • Bacterial ghosts as carrier and targeting systems for mucosal antigen delivery
    • Jalava K., Eko F.O., Riedmann E., Lubitz W.: Bacterial ghosts as carrier and targeting systems for mucosal antigen delivery. Expert. Rev. Vaccines, 2, 45-51 (2003)
    • (2003) Expert. Rev. Vaccines , vol.2 , pp. 45-51
    • Jalava, K.1    Eko, F.O.2    Riedmann, E.3    Lubitz, W.4
  • 45
    • 0036128741 scopus 로고    scopus 로고
    • Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica sv. Typhimurium vaccine
    • Kang H.Y., Srinivasan J., Curtiss R., 3rd: Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica sv. Typhimurium vaccine. Infect. Immun. 70, 1739-1749 (2002)
    • (2002) Infect. Immun. , vol.70 , pp. 1739-1749
    • Kang, H.Y.1    Srinivasan, J.2    Curtiss III, R.3
  • 47
    • 0033980073 scopus 로고    scopus 로고
    • The role of CpG motifs in innate immunity
    • Krieg A.M.: The role of CpG motifs in innate immunity. Curr Opin Immunol, 12, 35-43 (2000)
    • (2000) Curr Opin Immunol , vol.12 , pp. 35-43
    • Krieg, A.M.1
  • 48
    • 0036603641 scopus 로고    scopus 로고
    • How bacteria could cause cancer: One step at a time
    • Lax A.J., Thomas W.: How bacteria could cause cancer: one step at a time. Trends Microbiol. 10, 293-299 (2002)
    • (2002) Trends Microbiol. , vol.10 , pp. 293-299
    • Lax, A.J.1    Thomas, W.2
  • 49
    • 0035898938 scopus 로고    scopus 로고
    • Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H. pylori infection in mice
    • Lee M.H., Roussel Y., Wilks M., Tabaqchali S.: Expression of Helicobacter pylori urease subunit B gene in Lactococcus lactis MG1363 and its use as a vaccine delivery system against H. pylori infection in mice. Vaccine, 19, 3927-3935 (2001)
    • (2001) Vaccine , vol.19 , pp. 3927-3935
    • Lee, M.H.1    Roussel, Y.2    Wilks, M.3    Tabaqchali, S.4
  • 50
    • 0023789781 scopus 로고
    • Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR
    • Levine M.M., Kaper J.B., Herrington D., Ketley J., Losonsky G., Tacket C.O., Tall B., Cryz S.: Safety, immunogenicity, and efficacy of recombinant live oral cholera vaccines, CVD 103 and CVD 103-HgR. Lancet, 2, 467-470 (1988)
    • (1988) Lancet , vol.2 , pp. 467-470
    • Levine, M.M.1    Kaper, J.B.2    Herrington, D.3    Ketley, J.4    Losonsky, G.5    Tacket, C.O.6    Tall, B.7    Cryz, S.8
  • 51
    • 0028774376 scopus 로고
    • Helicobacter pylori and gastric cancer
    • Logan R.P.: Helicobacter pylori and gastric cancer. Lancet, 344, 1078-1079 (1994)
    • (1994) Lancet , vol.344 , pp. 1078-1079
    • Logan, R.P.1
  • 52
    • 0031255006 scopus 로고    scopus 로고
    • The mechanism of cholera toxin adjuvanticity
    • Lycke N.: The mechanism of cholera toxin adjuvanticity. Res. Immunol. 148, 504-520 (1997)
    • (1997) Res. Immunol. , vol.148 , pp. 504-520
    • Lycke, N.1
  • 53
    • 0026699224 scopus 로고
    • The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity
    • Lycke N., Tsuji T., Holmgren J.: The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol. 22, 2277-2281 (1992)
    • (1992) Eur. J. Immunol. , vol.22 , pp. 2277-2281
    • Lycke, N.1    Tsuji, T.2    Holmgren, J.3
  • 54
    • 0033962048 scopus 로고    scopus 로고
    • Use of the stationary phase inducible promoters, spv and dps, to drive heterologous antigen expression in Salmonella vaccine strains
    • Marshall D.G., Haque A., Fowler R., Del Guidice G., Dorman C.J., Dougan G., Bowe F.: Use of the stationary phase inducible promoters, spv and dps, to drive heterologous antigen expression in Salmonella vaccine strains. Vaccine, 18, 1298-1306 (2000)
    • (2000) Vaccine , vol.18 , pp. 1298-1306
    • Marshall, D.G.1    Haque, A.2    Fowler, R.3    Del Guidice, G.4    Dorman, C.J.5    Dougan, G.6    Bowe, F.7
  • 55
    • 0029891823 scopus 로고    scopus 로고
    • Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice
    • Mason H.S., Ball J.M., Shi J.J., Jiang X., Estes M.K., Arntzen C.J.: Expression of Norwalk virus capsid protein in transgenic tobacco and potato and its oral immunogenicity in mice. Proc. Natl. Acad. Sci. USA, 93, 5335-5340 (1996)
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5335-5340
    • Mason, H.S.1    Ball, J.M.2    Shi, J.J.3    Jiang, X.4    Estes, M.K.5    Arntzen, C.J.6
  • 56
    • 0032146489 scopus 로고    scopus 로고
    • Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): Potatoes expressing a synthetic LT-B gene
    • Mason H.S., Haq T.A., Clements J.D., Arntzen C.J.: Edible vaccine protects mice against Escherichia coli heat-labile enterotoxin (LT): potatoes expressing a synthetic LT-B gene. Vaccine, 16, 1336-1343 (1998)
    • (1998) Vaccine , vol.16 , pp. 1336-1343
    • Mason, H.S.1    Haq, T.A.2    Clements, J.D.3    Arntzen, C.J.4
  • 57
    • 0032876565 scopus 로고    scopus 로고
    • CpG DNA as mucosal adjuvant
    • McCluskie M.J., Davis H.L.: CpG DNA as mucosal adjuvant. Vaccine 18, 231-237 (1999)
    • (1999) Vaccine , vol.18 , pp. 231-237
    • McCluskie, M.J.1    Davis, H.L.2
  • 58
    • 0034703827 scopus 로고    scopus 로고
    • CpG DNA is an effective oral adjuvant to protein antigens in mice
    • McCluskie M.J., Weeratna R.D., Krieg A.M., Davis H.L.: CpG DNA is an effective oral adjuvant to protein antigens in mice. Vaccine, 19, 950-957 (2000)
    • (2000) Vaccine , vol.19 , pp. 950-957
    • McCluskie, M.J.1    Weeratna, R.D.2    Krieg, A.M.3    Davis, H.L.4
  • 59
    • 0034011783 scopus 로고    scopus 로고
    • Development of a nonantibiotic dominant marker for positively selecting expression plasmids in multivalent Salmonella vaccines
    • McNeill H.V., Sinha K.A., Hormaeche C.E., Lee J.J., Khan C.M.: Development of a nonantibiotic dominant marker for positively selecting expression plasmids in multivalent Salmonella vaccines. Appl. Environ. Microbiol. 66, 1216-1219 (2000)
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 1216-1219
    • McNeill, H.V.1    Sinha, K.A.2    Hormaeche, C.E.3    Lee, J.J.4    Khan, C.M.5
  • 60
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., Janeway C.A., Jr.: A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature, 388, 394-397 (1997)
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 61
    • 2342624566 scopus 로고    scopus 로고
    • Microarray reality checks in the context of a complex disease
    • Miklos G.L., Maleszka R.: Microarray reality checks in the context of a complex disease. Nat. Biotechnol. 22, 615-621 (2004)
    • (2004) Nat. Biotechnol. , vol.22 , pp. 615-621
    • Miklos, G.L.1    Maleszka, R.2
  • 62
    • 0035063575 scopus 로고    scopus 로고
    • Escherichia coli heat-labile enterotoxin B subunit is a more potent mucosal adjuvant than its closely related homologue, the B subunit of cholera toxin
    • Millar D.G., Hirst T.R., Snider D.P.: Escherichia coli heat-labile enterotoxin B subunit is a more potent mucosal adjuvant than its closely related homologue, the B subunit of cholera toxin. Infect. Immun. 69, 3476-3482 (2001)
    • (2001) Infect. Immun. , vol.69 , pp. 3476-3482
    • Millar, D.G.1    Hirst, T.R.2    Snider, D.P.3
  • 64
    • 0031800888 scopus 로고    scopus 로고
    • CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus
    • Moldoveanu Z., Love-Homan L., Huang W., Krieg A.: CpG DNA, a novel immune enhancer for systemic and mucosal immunization with influenza virus. Vaccine 16, 1216-1224 (1998)
    • (1998) Vaccine , vol.16 , pp. 1216-1224
    • Moldoveanu, Z.1    Love-Homan, L.2    Huang, W.3    Krieg, A.4
  • 66
    • 0030859151 scopus 로고    scopus 로고
    • Modulation of B-cell activation by the B subunit of Escherichia coli enterotoxin: Receptor interaction up-regulates MHC class II, B7, CD40, CD25 and ICAM-1
    • Nashar T.O., Hirst T.R., Williams N.A.: Modulation of B-cell activation by the B subunit of Escherichia coli enterotoxin: receptor interaction up-regulates MHC class II, B7, CD40, CD25 and ICAM-1. Immunology, 91, 572-578 (1997)
    • (1997) Immunology , vol.91 , pp. 572-578
    • Nashar, T.O.1    Hirst, T.R.2    Williams, N.A.3
  • 68
    • 0035825570 scopus 로고    scopus 로고
    • Novel use of anaerobically induced promoter, dmsA, for controlled expression of fragment C of tetanus toxin in live attenuated Salmonella enterica sv. Typhi strain CVD 908-htrA
    • Orr N., Galen J.E., Levine M.M.: Novel use of anaerobically induced promoter, dmsA, for controlled expression of fragment C of tetanus toxin in live attenuated Salmonella enterica sv. Typhi strain CVD 908-htrA. Vaccine, 19, 1694-1700 (2001)
    • (2001) Vaccine , vol.19 , pp. 1694-1700
    • Orr, N.1    Galen, J.E.2    Levine, M.M.3
  • 69
    • 0034733579 scopus 로고    scopus 로고
    • The mucosal adjuvanticity of two nontoxic mutants of Escherichia coli heat-labile enterotoxin varies with immunization routes
    • Park E.J., Chang J.H., Kim J.S., Yum J.S., Chung S.I.: The mucosal adjuvanticity of two nontoxic mutants of Escherichia coli heat-labile enterotoxin varies with immunization routes. Exp. Mol. Med. 32, 72-78 (2000)
    • (2000) Exp. Mol. Med. , vol.32 , pp. 72-78
    • Park, E.J.1    Chang, J.H.2    Kim, J.S.3    Yum, J.S.4    Chung, S.I.5
  • 70
    • 0034628526 scopus 로고    scopus 로고
    • The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences
    • Parkhill J., Barrell B.G. i wsp.: The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature, 403, 665-668 (2000)
    • (2000) Nature , vol.403 , pp. 665-668
    • Parkhill, J.1    Barrell, B.G.2
  • 71
    • 0037471406 scopus 로고    scopus 로고
    • Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives
    • Petrovska L., Lopes L., Simmons C.P., Pizza M., Dougan G., Chain B.M.: Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives. Vaccine, 21, 1445-1454 (2003)
    • (2003) Vaccine , vol.21 , pp. 1445-1454
    • Petrovska, L.1    Lopes, L.2    Simmons, C.P.3    Pizza, M.4    Dougan, G.5    Chain, B.M.6
  • 73
    • 0142147304 scopus 로고    scopus 로고
    • Reverse vaccinology and genomics
    • Rappuoli R., Covacci A.: Reverse vaccinology and genomics. Science, 302, 602 (2003)
    • (2003) Science , vol.302 , pp. 602
    • Rappuoli, R.1    Covacci, A.2
  • 74
    • 0032748077 scopus 로고    scopus 로고
    • Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins
    • Rappuoli R., Pizza M., Douce G., Dougan G.: Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins. Immunol. Today, 20, 493-500 (1999)
    • (1999) Immunol. Today , vol.20 , pp. 493-500
    • Rappuoli, R.1    Pizza, M.2    Douce, G.3    Dougan, G.4
  • 75
    • 0035132833 scopus 로고    scopus 로고
    • Protective mucosal immunity to ocular herpes simplex virus type 1 infection in mice by using Escherichia coli heat-labile enterotoxin B subunit as an adjuvant
    • Richards C.M., Aman A.T., Hirst T.R., Hill T.J., Williams N.A.: Protective mucosal immunity to ocular herpes simplex virus type 1 infection in mice by using Escherichia coli heat-labile enterotoxin B subunit as an adjuvant. J. Virol. 75, 1664-1671 (2001)
    • (2001) J. Virol. , vol.75 , pp. 1664-1671
    • Richards, C.M.1    Aman, A.T.2    Hirst, T.R.3    Hill, T.J.4    Williams, N.A.5
  • 76
    • 0027485331 scopus 로고
    • Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant
    • Rollwagen F.M., Pacheco N.D., Clements J.D., Pavlovskis O., Rollins D.M., Walker R.I.: Killed Campylobacter elicits immune response and protection when administered with an oral adjuvant. Vaccine, 11, 1316-1320 (1993)
    • (1993) Vaccine , vol.11 , pp. 1316-1320
    • Rollwagen, F.M.1    Pacheco, N.D.2    Clements, J.D.3    Pavlovskis, O.4    Rollins, D.M.5    Walker, R.I.6
  • 77
    • 0029610368 scopus 로고
    • Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability
    • Ruddock L.W., Ruston S.P., Kelly S.M., Price N.C., Freedman R.B., Hirst T.R.: Kinetics of acid-mediated disassembly of the B subunit pentamer of Escherichia coli heat-labile enterotoxin. Molecular basis of pH stability. J. Biol. Chem. 270, 29953-29958 (1995)
    • (1995) J. Biol. Chem. , vol.270 , pp. 29953-29958
    • Ruddock, L.W.1    Ruston, S.P.2    Kelly, S.M.3    Price, N.C.4    Freedman, R.B.5    Hirst, T.R.6
  • 78
    • 0037472387 scopus 로고    scopus 로고
    • Vaccine antigen production in transgenic plants: Strategies, gene constructs and perspectives
    • Sala F., Manuela Rigano M., Barbante A., Basso B., Walmsley A.M., Castiglione S.: Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectives. Vaccine, 21, 803-808 (2003)
    • (2003) Vaccine , vol.21 , pp. 803-808
    • Sala, F.1    Manuela Rigano, M.2    Barbante, A.3    Basso, B.4    Walmsley, A.M.5    Castiglione, S.6
  • 79
    • 0031931361 scopus 로고    scopus 로고
    • Simple sequence repeats in the Helicobacter pylori genome
    • Saunders N.J., Peden J.F., Hood D.W., Moxon E.R.: Simple sequence repeats in the Helicobacter pylori genome. Mol. Microbiol. 27, 1091-1098 (1998)
    • (1998) Mol. Microbiol. , vol.27 , pp. 1091-1098
    • Saunders, N.J.1    Peden, J.F.2    Hood, D.W.3    Moxon, E.R.4
  • 80
    • 0347353506 scopus 로고    scopus 로고
    • Adhesion of probiotic strains to the intestinal mucosa and interaction with pathogens
    • Servin A.L., Coconnier M.H.: Adhesion of probiotic strains to the intestinal mucosa and interaction with pathogens. Best Pract. Res. Clin. Gastroenterol. 17, 741-754 (2003)
    • (2003) Best Pract. Res. Clin. Gastroenterol. , vol.17 , pp. 741-754
    • Servin, A.L.1    Coconnier, M.H.2
  • 82
    • 0033562987 scopus 로고    scopus 로고
    • IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens
    • Staats H.F., Ennis F.A., Jr.: IL-1 is an effective adjuvant for mucosal and systemic immune responses when coadministered with protein immunogens. J Immunol, 162, 6141-6147 (1999)
    • (1999) J Immunol , vol.162 , pp. 6141-6147
    • Staats, H.F.1    Ennis Jr., F.A.2
  • 83
    • 0034766392 scopus 로고    scopus 로고
    • Microbiological and immunological strategies for treatment of inflammatory bowel disease
    • Steidler L.: Microbiological and immunological strategies for treatment of inflammatory bowel disease. Microbes Infect. 3, 1157-1166 (2001)
    • (2001) Microbes Infect. , vol.3 , pp. 1157-1166
    • Steidler, L.1
  • 85
    • 0026631468 scopus 로고
    • Construction of stable LamB-Shiga toxin B subunit hybrids: Analysis of expression in Salmonella typhimurium aroA strains and stimulation of B subunit-specific mucosal and serum antibody responses
    • Su G.F., Brahmbhatt H.N., Wehland J., Rohde M., Timmis K.N.: Construction of stable LamB-Shiga toxin B subunit hybrids: analysis of expression in Salmonella typhimurium aroA strains and stimulation of B subunit-specific mucosal and serum antibody responses. Infect. Immun. 60, 3345-3359 (1992)
    • (1992) Infect. Immun. , vol.60 , pp. 3345-3359
    • Su, G.F.1    Brahmbhatt, H.N.2    Wehland, J.3    Rohde, M.4    Timmis, K.N.5
  • 86
    • 0030758117 scopus 로고    scopus 로고
    • Safety and immunogenicity in humans of an attenuated Salmonella typhi vaccine vector strain expressing plasmid-encoded hepatitis B antigens stabilized by the Asd-balanced lethal vector system
    • Tacket C.O., Kelly S.M., Schodel F., Losonsky G., Nataro J.P., Edelman R., Levine M.M., Curtiss R., 3rd: Safety and immunogenicity in humans of an attenuated Salmonella typhi vaccine vector strain expressing plasmid-encoded hepatitis B antigens stabilized by the Asd-balanced lethal vector system. Infect. Immun. 65, 3381-3385 (1997)
    • (1997) Infect. Immun. , vol.65 , pp. 3381-3385
    • Tacket, C.O.1    Kelly, S.M.2    Schodel, F.3    Losonsky, G.4    Nataro, J.P.5    Edelman, R.6    Levine, M.M.7    Curtiss III, R.8
  • 87
    • 0031863854 scopus 로고    scopus 로고
    • Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato
    • Tacket C.O., Mason H.S., Losonsky G., Clements J.D., Levine M.M., Arntzen C.J.: Immunogenicity in humans of a recombinant bacterial antigen delivered in a transgenic potato. Nat. Med. 4, 607-609 (1998)
    • (1998) Nat. Med. , vol.4 , pp. 607-609
    • Tacket, C.O.1    Mason, H.S.2    Losonsky, G.3    Clements, J.D.4    Levine, M.M.5    Arntzen, C.J.6
  • 91
    • 0030960826 scopus 로고    scopus 로고
    • Induction of feline immuno-deficiency virus specific antibodies in cats with an attenuated Salmonella strain expressing the Gag protein
    • Tijhaar E.J., Siebehnk K.H., Karlas J.A., Burger M.C., Mooi F.R., Osterhaus A.D.: Induction of feline immuno-deficiency virus specific antibodies in cats with an attenuated Salmonella strain expressing the Gag protein. Vaccine, 15, 587-596 (1997)
    • (1997) Vaccine , vol.15 , pp. 587-596
    • Tijhaar, E.J.1    Siebehnk, K.H.2    Karlas, J.A.3    Burger, M.C.4    Mooi, F.R.5    Osterhaus, A.D.6
  • 92
    • 0032036427 scopus 로고    scopus 로고
    • Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin
    • Truitt R.L., Hanke C., Radke J., Mueller R., Barbieri J.T.: Glycosphingolipids as novel targets for T-cell suppression by the B subunit of recombinant heat-labile enterotoxin. Infect. Immun. 66, 1299-1308 (1998)
    • (1998) Infect. Immun. , vol.66 , pp. 1299-1308
    • Truitt, R.L.1    Hanke, C.2    Radke, J.3    Mueller, R.4    Barbieri, J.T.5
  • 93
    • 0034327167 scopus 로고    scopus 로고
    • Cutting edge: The mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues
    • van Ginkel F.W., Jackson R., Yuki Y., McGhee J.: Cutting edge: the mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues. J. Immunol. 165, 4778-4782 (2000)
    • (2000) J. Immunol. , vol.165 , pp. 4778-4782
    • Van Ginkel, F.W.1    Jackson, R.2    Yuki, Y.3    McGhee, J.4
  • 94
    • 0141559412 scopus 로고    scopus 로고
    • Differential signaling by CpG DNA in DCs and B cells: Not just TLR9
    • Verthelyi D., Zeuner R.A.: Differential signaling by CpG DNA in DCs and B cells: not just TLR9. Trends Immunol. 24, 519-522 (2003)
    • (2003) Trends Immunol. , vol.24 , pp. 519-522
    • Verthelyi, D.1    Zeuner, R.A.2
  • 95
    • 0032219522 scopus 로고    scopus 로고
    • Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: Induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen
    • Verweij W.R., de Haan L., Holtrop M., Agsteribbe E., Brands R., van Scharrenburg G.J., Wilschut J.: Mucosal immunoadjuvant activity of recombinant Escherichia coli heat-labile enterotoxin and its B subunit: induction of systemic IgG and secretory IgA responses in mice by intranasal immunization with influenza virus surface antigen. Vaccine, 16, 2069-2076 (1998)
    • (1998) Vaccine , vol.16 , pp. 2069-2076
    • Verweij, W.R.1    De Haan, L.2    Holtrop, M.3    Agsteribbe, E.4    Brands, R.5    Van Scharrenburg, G.J.6    Wilschut, J.7
  • 96
    • 0036160406 scopus 로고    scopus 로고
    • Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity
    • Wagner H.: Interactions between bacterial CpG-DNA and TLR9 bridge innate and adaptive immunity. Curr. Opin. Microbiol. 5, 62-69 (2002)
    • (2002) Curr. Opin. Microbiol. , vol.5 , pp. 62-69
    • Wagner, H.1
  • 97
    • 0036789803 scopus 로고    scopus 로고
    • Population biology of emerging and reemerging pathogens
    • Woolhouse M.E.: Population biology of emerging and reemerging pathogens. Trends Microbiol. 10, S3-7 (2002)
    • (2002) Trends Microbiol. , vol.10
    • Woolhouse, M.E.1
  • 98
    • 0031986242 scopus 로고    scopus 로고
    • Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant
    • Wu H.Y., Russell M.W.: Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxin B subunit as an adjuvant. Vaccine, 16, 286-292 (1998)
    • (1998) Vaccine , vol.16 , pp. 286-292
    • Wu, H.Y.1    Russell, M.W.2
  • 99
    • 0030886013 scopus 로고    scopus 로고
    • Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector
    • Wu S., Pascual D.W., Lewis G.K., Hone D.M.: Induction of mucosal and systemic responses against human immunodeficiency virus type 1 glycoprotein 120 in mice after oral immunization with a single dose of a Salmonella-HIV vector. AIDS Res. Hum. Retroviruses, 13, 1187-1194 (1997)
    • (1997) AIDS Res. Hum. Retroviruses , vol.13 , pp. 1187-1194
    • Wu, S.1    Pascual, D.W.2    Lewis, G.K.3    Hone, D.M.4
  • 100
    • 0035018196 scopus 로고    scopus 로고
    • A plant-based multicomponent vaccine protects mice from enteric diseases
    • Yu J., Langridge W.H.: A plant-based multicomponent vaccine protects mice from enteric diseases. Nat. Biotechnol. 19, 548-552 (2001)
    • (2001) Nat. Biotechnol. , vol.19 , pp. 548-552
    • Yu, J.1    Langridge, W.H.2


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