Synthesis of 6-(alkoxymethyl)- and 6-(alkylsulfanylmethyl)furo[2,3-d] pyrimidin-2(3H)-one analogues

Canadian Journal of Chemistry

Volumn 84, Issue 4, 2006, Pages 561-568

  Janeba, Zlatko ^a,b   Maklad, Noha ^a,c   Robins, Morris J ^a  

^a Brigham Young University   (United States)

^b Moravek Biochemicals Inc   (United States)

^c PFIZER INC   (United States)

Author keywords

Alkyl; Ether and thioether derivatives of furo 2,3 d pyrimidin 2(3H) one; Furo 2,3 d pyrimidin 2(3H) ones

Indexed keywords

ALCOHOLS; CHLORIDE MINERALS; DECOMPOSITION; ETHERS; POTASSIUM COMPOUNDS; SOLUTIONS; SYNTHESIS (CHEMICAL);

ALKYL; ETHER AND THIOETHER DERIVATIVES OF FURO[2,3-D]PYRIMIDIN-2(3H)-ONE; FURO[2,3-D]PYRIMIDIN-2(3H)-ONES; REGIOISOMERS;

PARAFFINS;

3 ALKYL 6 (ALKOXYMETHYL)FUROPYRIMIDIN 2(3H) ONE DERIVATIVE; 3 BUTYL 6 (CHLOROMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 BUTYL 6 (HYDROXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 BUTYL 6 (OCTYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 DECYL 6 (HEXYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 DECYL 6 (HYDROXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 DECYL 6 (OCTYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 DODECYL 6 (HYDROXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 DODECYL 6 (OCTYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 HEXYL 6 (HEXYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 HEXYL 6 (PROPYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 3 OCTYL 6 (OCTYLOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (ACETYLSULFANYLMETHYL) 3 BUTYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (ACETYLSULFANYLMETHYL) 3 DECYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (ACETYLSULFANYLMETHYL) 3 HEXYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (ACETYLSULFANYLMETHYL) 3 OCTYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (ALKOXYMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE DERIVATIVE; 6 (ALKYLSULFANYLMETHYL)FURO[2,3 D]PYRIMIDIN 2(3H) ONE DERIVATIVE; 6 (BUTYLOXYMETHYL) 3 DECYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (BUTYLOXYMETHYL) 3 DODECYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (BUTYLOXYMETHYL) 3 HEXYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (BUTYLOXYMETHYL) 3 OCTYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (CHLOROMETHYL) 3 DECYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (CHLOROMETHYL) 3 DODECYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (CHLOROMETHYL) 3 HEXYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (CHLOROMETHYL) 3 OCTYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (HEXYLOXYMETHYL) 3 OCTYLFURO[2,3 D]PYRIMIDIN 2(3H) ONE; 6 (HYDROXYMETHYL)FURIO[2,3 D]PYRIMIDIN 2(3H) ONE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ALKYLATION; ARTICLE; DEACETYLATION; DRUG SYNTHESIS; SOLVOLYSIS; ULTRASOUND;

EID: 33745894150     PISSN: 00084042     EISSN: None     Source Type: Journal    
DOI: 10.1139/V06-042     Document Type: Article

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