Discovery of a New Family of Inhibitors of Human Cytomegalovirus (HCMV) Based upon Lipophilic Alkyl Furano Pyrimidine Dideoxy Nucleosides: Action via a Novel Non-Nucleosidic Mechanism

Journal of Medicinal Chemistry

Volumn 47, Issue 7, 2004, Pages 1847-1851

  McGuigan, Christopher ^a   Pathirana, Ranjith N ^a,c   Snoeck, Robert ^b   Andrei, Graciela ^b   De Clercq, Erik ^b   Balzarini, Jan ^b  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF RUHUNA   (Sri Lanka)

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; BENZIMIDAVIR; BENZIMIDAZOLE DERIVATIVE; CIDOFOVIR; FOSCARNET; FURAN DERIVATIVE; GANCICLOVIR; NUCLEOSIDE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; CYTOTOXICITY; DNA SYNTHESIS; DRUG MECHANISM; HUMAN CYTOMEGALOVIRUS; LIPOPHILICITY; NONHUMAN; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CELL LINE; CYTOMEGALOVIRUS; FURANS; HUMANS; PYRIMIDINE NUCLEOSIDES; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

EID: 1642272920     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm030857h     Document Type: Article

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