Kinetic investigation of Escherichia coli RNA polymerase mutants that influence nucleotide discrimination and transcription fidelity

Journal of Biological Chemistry

Volumn 281, Issue 27, 2006, Pages 18677-18683

  Holmes, Shannon F ^a,d   Santangelo, Thomas J ^c,e   Cunningham, Candice K ^a   Roberts, Jeffrey W ^c   Erie, Dorothy A ^a,b  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Department of Molecular Biology and Genetics   (United States)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CELL MEMBRANES; CRYSTAL STRUCTURE; ENZYME KINETICS; ESCHERICHIA COLI; RNA;

NUCLEOSIDE TRIPHOSPHATE (NTP) BINDING; NUCLEOTIDES; POLYMERASE MUTANTS;

ENZYMES;

BACTERIAL ENZYME; NUCLEOSIDE TRIPHOSPHATE; NUCLEOTIDE; RNA POLYMERASE;

ARTICLE; CRYSTAL STRUCTURE; ENZYME STRUCTURE; ESCHERICHIA COLI; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BASE SEQUENCE; BINDING SITES; DNA-DIRECTED RNA POLYMERASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; KINETICS; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI;

EID: 33745808766     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M600543200     Document Type: Article

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