메뉴 건너뛰기




Volumn 126, Issue 1, 2006, Pages 113-118

Overexpression of fatty acid synthase in ulcerative colitis

Author keywords

Fatty acid synthase; Inflammation; Ulcerative colitis

Indexed keywords

FATTY ACID SYNTHASE; LONG CHAIN FATTY ACID;

EID: 33745771550     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/PUBVQNDNVQKJVC8M     Document Type: Article
Times cited : (4)

References (36)
  • 1
    • 0024315871 scopus 로고
    • Fatty acid synthase, a proficient multifunctional enzyme
    • Wakil SJ. Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry. 1989;28:4523-4530.
    • (1989) Biochemistry , vol.28 , pp. 4523-4530
    • Wakil, S.J.1
  • 2
    • 0034718771 scopus 로고    scopus 로고
    • Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway
    • Swinnen JV, Heemers H, Deboel L, et al. Stimulation of tumor-associated fatty acid synthase expression by growth factor activation of the sterol regulatory element-binding protein pathway. Oncogene. 2000;19:5173-5181.
    • (2000) Oncogene , vol.19 , pp. 5173-5181
    • Swinnen, J.V.1    Heemers, H.2    Deboel, L.3
  • 3
    • 0034011584 scopus 로고    scopus 로고
    • Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells
    • Kusakabe T, Maeda M, Hoshi N, et al. Fatty acid synthase is expressed mainly in adult hormone-sensitive cells or cells with high lipid metabolism and in proliferating fetal cells. J Histochem Cytochem. 2000;48:613-622.
    • (2000) J Histochem Cytochem , vol.48 , pp. 613-622
    • Kusakabe, T.1    Maeda, M.2    Hoshi, N.3
  • 4
    • 0031845136 scopus 로고    scopus 로고
    • Nutritional and hormonal regulation of enzymes in fat synthesis: Studies of fatty acid synthase and mitochondrial glycerol-3 phosphate acyltransferase gene transcription
    • Sul HS, Wang D. Nutritional and hormonal regulation of enzymes in fat synthesis: studies of fatty acid synthase and mitochondrial glycerol-3 phosphate acyltransferase gene transcription. Annu Rev Nutr. 1998;18:331-351.
    • (1998) Annu Rev Nutr , vol.18 , pp. 331-351
    • Sul, H.S.1    Wang, D.2
  • 5
    • 0023664688 scopus 로고
    • Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells
    • Chalbos D, Chambon M, Aihaud G, et al. Fatty acid synthetase and its mRNA are induced by progestins in breast cancer cells. J Biol Chem. 1987;262:9923-9926.
    • (1987) J Biol Chem , vol.262 , pp. 9923-9926
    • Chalbos, D.1    Chambon, M.2    Aihaud, G.3
  • 6
    • 0024453198 scopus 로고
    • Haptoglobin-related protein (Hpr) epitopes in breast cancer as a predictor of recurrence of the disease
    • Kuhajda FP, Piantadosi S, Pasternack GR. Haptoglobin-related protein (Hpr) epitopes in breast cancer as a predictor of recurrence of the disease. N Engl J Med. 1989;321:636-641.
    • (1989) N Engl J Med , vol.321 , pp. 636-641
    • Kuhajda, F.P.1    Piantadosi, S.2    Pasternack, G.R.3
  • 7
    • 0030063936 scopus 로고    scopus 로고
    • Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients
    • Alò PL, Visca P, Marci A, et al. Expression of fatty acid synthase (FAS) as a predictor of recurrence in stage I breast carcinoma patients. Cancer. 1996;77:474-482.
    • (1996) Cancer , vol.77 , pp. 474-482
    • Alò, P.L.1    Visca, P.2    Marci, A.3
  • 8
    • 0028875706 scopus 로고
    • OA-519 (fatty acid synthase) as an independent predictor of pathological stage in adenocarcinoma of the prostate
    • Epstein JI, Carmichael M, Partin AW. OA-519 (fatty acid synthase) as an independent predictor of pathological stage in adenocarcinoma of the prostate. Urology. 1995;45:81-86.
    • (1995) Urology , vol.45 , pp. 81-86
    • Epstein, J.I.1    Carmichael, M.2    Partin, A.W.3
  • 9
    • 0031021649 scopus 로고    scopus 로고
    • Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia
    • Rashid A, Pizer ES, Moga M, et al. Elevated expression of fatty acid synthase and fatty acid synthetic activity in colorectal neoplasia. Am J Pathol. 1997;150:201-208.
    • (1997) Am J Pathol , vol.150 , pp. 201-208
    • Rashid, A.1    Pizer, E.S.2    Moga, M.3
  • 10
    • 0033386501 scopus 로고    scopus 로고
    • Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa
    • Visca P Alò PL, Del Nonno F, et al. Immunohistochemical expression of fatty acid synthase, apoptotic-regulating genes, proliferating factors, and ras protein product in colorectal adenomas, carcinomas, and adjacent nonneoplastic mucosa. Clin Cancer Res. 1999;5:4111-4118.
    • (1999) Clin Cancer Res , vol.5 , pp. 4111-4118
    • Visca, P.1    Alò, P.L.2    Del Nonno, F.3
  • 11
    • 0033808261 scopus 로고    scopus 로고
    • The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung
    • Piyathilake CJ, Frost AR, Manne U, et al. The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung. Hum Pathol. 2000;31:1068-1073.
    • (2000) Hum Pathol , vol.31 , pp. 1068-1073
    • Piyathilake, C.J.1    Frost, A.R.2    Manne, U.3
  • 12
    • 20144389083 scopus 로고    scopus 로고
    • Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma
    • Visca P, Sebastiani V, Botti C, et al. Fatty acid synthase (FAS) is a marker of increased risk of recurrence in lung carcinoma. Anticancer Res. 2004;24:4169-4173.
    • (2004) Anticancer Res , vol.24 , pp. 4169-4173
    • Visca, P.1    Sebastiani, V.2    Botti, C.3
  • 13
    • 0036151105 scopus 로고    scopus 로고
    • Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach
    • Kusakabe T, Nashimoto A, Honna K, et al. Fatty acid synthase is highly expressed in carcinoma, adenoma and in regenerative epithelium and intestinal metaplasia of the stomach. Histopathology. 2002;40:71-79.
    • (2002) Histopathology , vol.40 , pp. 71-79
    • Kusakabe, T.1    Nashimoto, A.2    Honna, K.3
  • 14
    • 0036385719 scopus 로고    scopus 로고
    • Activation of fatty acid synthesis during neoplastic transformation: Role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase
    • Yang YA, Han WF, Morin PJ, et al. Activation of fatty acid synthesis during neoplastic transformation: role of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Exp Cell Res. 2002;279:80-90.
    • (2002) Exp Cell Res , vol.279 , pp. 80-90
    • Yang, Y.A.1    Han, W.F.2    Morin, P.J.3
  • 15
    • 0034119596 scopus 로고    scopus 로고
    • Risk of cancer in inflammatory bowel disease (IBD)
    • Tsianos EV. Risk of cancer in inflammatory bowel disease (IBD). Eur J Intern Med. 2000;11:75-78.
    • (2000) Eur J Intern Med , vol.11 , pp. 75-78
    • Tsianos, E.V.1
  • 16
    • 0035865012 scopus 로고    scopus 로고
    • Cancer risk in patients with inflammatory bowel disease: A population-based study
    • Bernstein CN, Blanchard JF, Kliewer E, et al. Cancer risk in patients with inflammatory bowel disease: a population-based study. Cancer. 2001;91:854-862.
    • (2001) Cancer , vol.91 , pp. 854-862
    • Bernstein, C.N.1    Blanchard, J.F.2    Kliewer, E.3
  • 18
    • 0034650757 scopus 로고    scopus 로고
    • Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts
    • Pizer ES, Thupari J, Fang Han W, et al. Malonyl-coenzyme-A is a potential mediator of cytotoxicity induced by fatty-acid synthase inhibition in human breast cancer cells and xenografts. Cancer Res. 2000;60:213-218.
    • (2000) Cancer Res , vol.60 , pp. 213-218
    • Pizer, E.S.1    Thupari, J.2    Fang Han, W.3
  • 19
    • 0742324875 scopus 로고    scopus 로고
    • Fatty acid synthase is a marker of increased risk of recurrence in endometrial carcinoma
    • Sebastiani V, Visca P, Botti C, et al. Fatty acid synthase is a marker of increased risk of recurrence in endometrial carcinoma. Gynecol Oncol 2004;92:101-105.
    • (2004) Gynecol Oncol , vol.92 , pp. 101-105
    • Sebastiani, V.1    Visca, P.2    Botti, C.3
  • 20
    • 0029829119 scopus 로고    scopus 로고
    • Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer
    • Shurbaji MS, Kalbfleisch JH, Thurmond TS. Immunohistochemical detection of a fatty acid synthase (OA-519) as a predictor of progression of prostate cancer. Hum Pathol. 1996;27:917-921.
    • (1996) Hum Pathol , vol.27 , pp. 917-921
    • Shurbaji, M.S.1    Kalbfleisch, J.H.2    Thurmond, T.S.3
  • 21
    • 0031007392 scopus 로고    scopus 로고
    • Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival
    • Gansler TS, Hardman W, Hunt DA, et al. Increased expression of fatty acid synthase (OA-519) in ovarian neoplasms predicts shorter survival. Hum Pathol 1997;28:686-692.
    • (1997) Hum Pathol , vol.28 , pp. 686-692
    • Gansler, T.S.1    Hardman, W.2    Hunt, D.A.3
  • 22
    • 0028301959 scopus 로고
    • Fatty acid synthesis: A potential selective target for antineoplastic therapy
    • Kuhajda FP, Jenner K, Wood FD, et al. Fatty acid synthesis: a potential selective target for antineoplastic therapy. Proc Natl Acad Sci U S A. 1994;91:6379-6383.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 6379-6383
    • Kuhajda, F.P.1    Jenner, K.2    Wood, F.D.3
  • 23
    • 0036939333 scopus 로고    scopus 로고
    • Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis
    • Yukawa M, Iizuka M, Horie Y, et al. Systemic and local evidence of increased Fas-mediated apoptosis in ulcerative colitis. Int J Colorectal Dis. 2002;17:70-76.
    • (2002) Int J Colorectal Dis , vol.17 , pp. 70-76
    • Yukawa, M.1    Iizuka, M.2    Horie, Y.3
  • 24
    • 0028864991 scopus 로고
    • A distinct array of pro inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung HC, Eckmann L, Yang SK, et al. A distinct array of pro inflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest. 1995;95:55-65.
    • (1995) J Clin Invest , vol.95 , pp. 55-65
    • Jung, H.C.1    Eckmann, L.2    Yang, S.K.3
  • 25
    • 0023220709 scopus 로고
    • Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo
    • Feingold KR, Grunfeld C. Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo. J Clin Invest. 1987;80:184-190.
    • (1987) J Clin Invest , vol.80 , pp. 184-190
    • Feingold, K.R.1    Grunfeld, C.2
  • 26
    • 0027745739 scopus 로고
    • Fibroblast growth factor-1 induces phosphofructokinase, fatty acid synthase and Ca-ATPase mRN a expression in NIH 3T3 cells
    • Hsu DKW, Donohue PJ, Alberts GF, et al. Fibroblast growth factor-1 induces phosphofructokinase, fatty acid synthase and Ca-ATPase mRN A expression in NIH 3T3 cells. Biochem Biophys Res Commun. 1993;197:1483-1491.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 1483-1491
    • Hsu, D.K.W.1    Donohue, P.J.2    Alberts, G.F.3
  • 27
    • 0032147199 scopus 로고    scopus 로고
    • Fatty acid synthase expression in endometrial carcinoma
    • Pizer ES, Lax SF, Kuhajda FP, et al. Fatty acid synthase expression in endometrial carcinoma. Cancer. 1998;1:528-537.
    • (1998) Cancer , vol.1 , pp. 528-537
    • Pizer, E.S.1    Lax, S.F.2    Kuhajda, F.P.3
  • 28
    • 0031043030 scopus 로고    scopus 로고
    • The mitochondrial carnitine palmitoyltransferase system: From concept to molecular analysis
    • McGarry JD, Brown NF. The mitochondrial carnitine palmitoyltransferase system: from concept to molecular analysis. Eur J Biochem. 1997;244:1-14.
    • (1997) Eur J Biochem , vol.244 , pp. 1-14
    • McGarry, J.D.1    Brown, N.F.2
  • 29
    • 0242694902 scopus 로고    scopus 로고
    • Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells
    • Zhou W, Simpson PJ, McFadden JM, et al. Fatty acid synthase inhibition triggers apoptosis during S phase in human cancer cells. Cancer Res. 2003;63:7330-7337.
    • (2003) Cancer Res , vol.63 , pp. 7330-7337
    • Zhou, W.1    Simpson, P.J.2    McFadden, J.M.3
  • 30
    • 9144219529 scopus 로고    scopus 로고
    • C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism
    • Landreet LE, Hanlon AL, Strong DW, et al. C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism. J Biol Chem. 2004;279:3817-3827.
    • (2004) J Biol Chem , vol.279 , pp. 3817-3827
    • Landreet, L.E.1    Hanlon, A.L.2    Strong, D.W.3
  • 31
    • 0027409425 scopus 로고
    • Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA
    • Semenkovich CF, Coleman T, Goforth R. Physiologic concentrations of glucose regulate fatty acid synthase activity in HepG2 cells by mediating fatty acid synthase mRNA. J Biol Chem. 1993;268:6961-6970.
    • (1993) J Biol Chem , vol.268 , pp. 6961-6970
    • Semenkovich, C.F.1    Coleman, T.2    Goforth, R.3
  • 32
    • 0031013369 scopus 로고    scopus 로고
    • Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis
    • Paumen MB, Ishida Y, Muramatsu M, et al. Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis. J Biol Chem. 1997;272:3324-3329.
    • (1997) J Biol Chem , vol.272 , pp. 3324-3329
    • Paumen, M.B.1    Ishida, Y.2    Muramatsu, M.3
  • 33
    • 0033090417 scopus 로고    scopus 로고
    • The yins and yangs of ceramide
    • Sharma K, Shi Y. The yins and yangs of ceramide. Cell Res. 1999;9:1-10.
    • (1999) Cell Res , vol.9 , pp. 1-10
    • Sharma, K.1    Shi, Y.2
  • 34
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • Hannun YA. Functions of ceramide in coordinating cellular responses to stress. Science. 1996;274:1855-1859.
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, Y.A.1
  • 35
    • 0026706275 scopus 로고
    • Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice
    • Wood LC, Jackson SM, Elies PM, et al. Cutaneous barrier perturbation stimulates cytokine production in the epidermis of mice. J Clin Invest. 1992;90:482-487.
    • (1992) J Clin Invest , vol.90 , pp. 482-487
    • Wood, L.C.1    Jackson, S.M.2    Elies, P.M.3
  • 36
    • 0028909356 scopus 로고
    • Cutaneous permeability barrier disruption increases fatty acid synthetic enzyme activity in the epidermis of hairless mice
    • Ottey KA, Wood LC, Grunfeld C, et al. Cutaneous permeability barrier disruption increases fatty acid synthetic enzyme activity in the epidermis of hairless mice. J Invest Dermatol. 1995;104:401-404.
    • (1995) J Invest Dermatol , vol.104 , pp. 401-404
    • Ottey, K.A.1    Wood, L.C.2    Grunfeld, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.