Topology of yeast Ndc1p: Predictions for the human NDC1/NET3 homologue

Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology

Volumn 288, Issue 7, 2006, Pages 681-694

  Lau, Corine K ^a   Delmar, Valerie A ^a   Forbes, Douglass J ^a,b  

^a SECTION OF CELL AND DEVELOPMENTAL BIOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

NDC1; NET3; Nuclear envelope; Nuclear pore; Nucleoporin; Pore membrane proteins; Spindle pole body; Topology

Indexed keywords

AMINO ACID; INTEGRAL MEMBRANE PROTEIN NDC1P; MEMBRANE PROTEIN; PROTEIN NDC1; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS MEMBRANE; CONFERENCE PAPER; EUKARYOTE; HUMAN; MICROTUBULE ORGANIZING CENTER; MOLECULAR EVOLUTION; NONHUMAN; NUCLEAR PORE COMPLEX; NUCLEOTIDE SEQUENCE; PREDICTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; SPINDLE POLE BODY;

AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; HUMANS; MOLECULAR SEQUENCE DATA; NUCLEAR ENVELOPE; NUCLEAR PORE; NUCLEAR PORE COMPLEX PROTEINS; NUCLEAR PROTEINS; PHYLOGENY; PREDICTIVE VALUE OF TESTS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

EUKARYOTA; METAZOA; VERTEBRATA;

EID: 33745760280     PISSN: 0003276X     EISSN: 15524892     Source Type: Journal    
DOI: 10.1002/ar.a.20335     Document Type: Conference Paper

References (60)

1. Antonin W, Franz C, Haselmann U, Antony C, Mattaj IW. 2005. The integral membrane nucleoporin pom121 functionally links nuclear pore complex assembly and nuclear envelope formation. Mol Cell 17:83-92.
2. Belgareh N, Rabut G, Bai SW, van Overbeek M, Beaudouin J, Daigle N, Zatsepina OV, Pasteau F, Labas V, Fromont-Racine M, Ellenberg J, Doye V. 2001. An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells. J Cell Biol 154:1147-1160.
3. Burke B, Ellenberg J. 2002. Remodelling the walls of the nucleus. Nat Rev Mol Cell Biol 3:487-497.
4. Chial HJ, Rout MP, Giddings TH Jr, Winey M. 1998. Saccharomyces cerevisiae Ndc1p is a shared component of nuclear pore complexes and spindle pole bodies. J Cell Biol 143:1789-1800.
5. Chook YM, Blobel G. 2001. Karyopherins and nuclear import. Curr Opin Struct Biol 11:703-715.
6. Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ. 2002. Proteomic analysis of the mammalian nuclear pore complex. J Cell Biol 158:915-927.
7. Cronshaw JM, Matunis MJ. 2003. The nuclear pore complex protein ALADIN is mislocalized in triple A syndrome. Proc Natl Acad Sci USA 100:5823-5827.
8. Devos D, Dokudovskaya S, Alber F, Williams R, Chait BT, Sali A, Rout MP. 2004. Components of coated vesicles and nuclear pore complexes share a common molecular architecture. PLoS Biol 2:E380.
9. Drummond SP, Wilson KL. 2002. Interference with the cytoplasmic tail of gp210 disrupts "close apposition" of nuclear membranes and blocks nuclear pore dilation. J Cell Biol 158:53-62.
10. Enarson P, Rattner JB, Ou Y, Miyachi K, Horigome T, Fritzler MJ. 2004. Autoantigens of the nuclear pore complex. J Mol Med 82:423-433.
11. Fahrenkrog B, Aebi U. 2003. The nuclear pore complex: nucleocytoplasmic transport and beyond. Nat Rev Mol Cell Biol 10:757-766.
12. Fahrenkrog B, Koser J, Aebi U. 2004. The nuclear pore complex: a jack of all trades? Trends Biochem Sci 29:175-182.
13. Gafvelin G, Sakaguchi M, Andersson H, von Heijne G. 1997. Topological rules for membrane protein assembly in eukaryotic cells. J Biol Chem 272:6119-6127.
14. Gruenbaum Y, Margalit A, Goldman RD, Shumaker DK, Wilson KL. 2005. The nuclear lamina comes of age. Nat Rev Mol Cell Biol 6:21-31.
15. Harel A, Chan RC, Lachish-Zalait A, Zimmerman E, Elbaum M, Forbes DJ. 2003a. Importin beta negatively regulates nuclear membrane fusion and nuclear pore complex assembly. Mol Biol Cell 14:4387-4396.
16. Harel A, Orjalo AV, Vincent T, Lachish-Zalait A, Vasu S, Shah S, Zimmerman E, Elbaum M, Forbes DJ. 2003b. Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. Mol Cell 11:853-864.
17. Harel A, Forbes DJ. 2004. Importin beta: conducting a much larger cellular symphony. Mol Cell 16:319-330.
18. Hetzer M, Bilbao-Cortes D, Walther TC, Gruss OJ, Mattaj IW. 2000. GTP hydrolysis by Ran is required for nuclear envelope assembly. Mol Cell 5:1013-1024.
19. Hetzer MW, Walther TC, Mattaj IW. 2005. Pushing the envelope: structure, function, and dynamics of the nuclear periphery. Annu Rev Cell Dev Biol 21:347-380.
20. Holaska JM, Wilson KL, Mansharamani M. 2002. The nuclear envelope, lamins and nuclear assembly. Curr Opin Cell Biol 14:357-364.
21. Hutchison CJ. 2002. Lamins: building blocks or regulators of gene expression? Nat Rev Mol Cell Biol 3:848-858.
22. Jaspersen SL, Winey M. 2004. The budding yeast spindle pole body: structure, duplication, and function. Annu Rev Cell Dev Biol 20:1-28.
23. Kau TR, Way JC, Silver PA. 2004. Nuclear transport and cancer: from mechanism to intervention. Nat Rev Cancer 4:106-117.
24. Lau CK, Giddings TH Jr, Winey M. 2004. A novel allele of Saccharomyces cerevisiae NDC1 reveals a potential role for the spindle pole body component Ndc1p in nuclear pore assembly. Eukaryot Cell 3:447-458.
25. Liu J, Prunuske AJ, Fager AM, Ullman KS. 2003. The COPI complex functions in nuclear envelope breakdown and is recruited by the nucleoporin Nup153. Dev Cell 5:487-498.
26. Lohka MJ, Masui Y. 1984. Roles of cytosol and cytoplasmic particles in nuclear envelope assembly and sperm pronuclear formation in cell-free preparations from amphibian eggs. J Cell Biol 98:1222-1230.
27. Loiodice I, Alves A, Rabut G, Van Overbeek M, Ellenberg J, Sibarita JB, Doye V. 2004. The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis. Mol Biol Cell 15:3333-3344.
28. Macaulay C, Forbes DJ. 1996. Assembly of the nuclear pore: biochemically distinct steps revealed with NEM, GTP gamma S, and BAPTA. J Cell Biol 132:5-20.
29. Mans BJ, Anantharaman V, Aravind L, Koonin EV. 2004. Comparative genomics, evolution and origins of the nuclear envelope and nuclear pore complex. Cell Cycle 3:1612-1637.
30. Moore MA. 2005. Converging pathways in leukemogenesis and stem cell self-renewal. Exp Hematol 33:719-737.
31. Mounkes LC, Stewart CL. 2004. Aging and nuclear organization: lamins and progeria. Curr Opin Cell Biol 16:322-327.
32. Newport J. 1987. Nuclear reconstitution in vitro: stages of assembly around protein-free DNA. Cell 48:205-217.
33. Nilsson J, Persson B, von Heijne G. 2005. Comparative analysis of amino acid distributions in integral membrane proteins from 107 genomes. Proteins 60:606-616.
34. O'Toole ET, Winey M, McIntosh JR. 1999. High-voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast Saccharomyces cerevisiae. Mol Biol Cell 10:2017-2031.
35. Paschal BM. 2002. Translocation through the nuclear pore complex. Trends Biochem Sci 27:593-596.
36. Pemberton LF, Paschal BM. 2005. Mechanisms of receptor-mediated nuclear import and nuclear export. Traffic 6:187-198.
37. Peters R. 2005. Translocation through the nuclear pore complex: selectivity and speed by reduction-of-dimensionality. Traffic 6:421-427.
38. Pollex RL, Hegele RA. 2004. Hutchinson-Gilford progeria syndrome. Clin Genet 66:375-381.
39. Rout MP, Aitchison JD, Suprapto A, Hjertaas K, Zhao Y, Chait BT. 2000. The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148:635-651.
40. Rout MP, Aitchison JD. 2001. The nuclear pore complex as a transport machine. J Biol Chem 276:16593-16596.
41. Sakaguchi M. 2002. Autonomous and heteronomous positioning of transmembrane segments in multispanning membrane protein. Biochem Biophys Res Commun 296:1-4.
42. Schirmer EC, Florens L, Guan T, Yates JR III, Gerace L. 2003. Nuclear membrane proteins with potential disease links found by subtractive proteomics. Science 301:1380-1382.
43. Schuldt A. 2003. Nuclear pore assembly: locating the linchpin. Nat Cell Biol 6:497.
44. Schwartz TU. 2005. Modularity within the architecture of the nuclear pore complex. Curr Opin Struct Biol 15:221-226.
45. Shearer AG, Hampton RY. 2004. Structural control of endoplasmic reticulum-associated degradation: effect of chemical chaperones on 3-hydroxy-3-methylglutaryl-CoA reductase. J Biol Chem 279:188-196.
46. Smith ED, Kudlow BA, Frock RL, Kennedy BK. 2005. A-type nuclear lamins, progerias and other degenerative disorders. Mech Ageing Dev 126:447-460.
47. Strom AC, Weis K. 2001. Importin-beta-like nuclear transport receptors. Genome Biol 2:3008.
48. Suntharalingam M, Wente SR. 2003. Peering through the pore: nuclear pore complex structure, assembly, and function. Dev Cell 4:775-789.
49. Vasu SK, Forbes DJ. 2001. Nuclear pores and nuclear assembly. Curr Opin Cell Biol 13:363-375.
50. Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ. 2001. Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export. J Cell Biol 155:339-354.
51. von Heijne G. 1989. Control of topology and mode of assembly of a polytopic membrane protein by positively charged residues. Nature 341:456-458.
52. Walther TC, Alves A, Pickersgill H, Loiodice I, Hetzer M, Galy V, Hulsmann BB, Kocher T, Wilm M, Allen T, Mattaj IW, Doye V. 2003a. The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell 113:195-206.
53. Walther TC, Askjaer P, Gentzel M, Habermann A, Griffiths G, Wilm M, Mattaj IW, Hetzer M. 2003b. RanGTP mediates nuclear pore complex assembly. Nature 424:689-694.
54. Weis K. 2003. Regulating access to the genome: nucleocytoplasmic transport throughout the cell cycle. Cell 112:441-451.
55. +: a gene required for cell cycle-dependent spindle pole body anchoring in the nuclear envelope and biopolar spindle formation in Schizosaccharomyces pombe. Mol Biol Cell 9:2839-2855.
56. Whittaker GR, Kann M, Helenius A. 2000. Viral entry into the nucleus. Annu Rev Cell Dev Biol 16:627-651.
57. Wilson KL, Wiese C. 1996. Reconstituting the nuclear envelope and endoplasmic reticulum in vitro. Semin Cell Dev Biol 7:487-496.
58. Winey M, Goetsch L, Baum P, Byers B. 1991. MPS1 and MPS2: novel yeast genes defining distinct steps of spindle pole body duplication. J Cell Biol 114:745-754.
59. Winey M, Hoyt MA, Chan C, Goetsch L, Botstein D, Byers B. 1993. NDC1: a nuclear periphery component required for yeast spindle pole body duplication. J Cell Biol 122:743-751.
60. Wozniak RW, Blobel G, Rout MP. 1994. POM152 is an integral protein of the pore membrane domain of the yeast nuclear envelope. J Cell Biol 125:31-42.