Antiviral activity of small interfering RNAs: Specificity testing using heterologous virus reveals interferon-related effects overlooked by conventional mismatch controls

Virology

Volumn 349, Issue 1, 2006, Pages 134-141

  Schyth, Brian Dall ^a,b   Lorenzen, Niels ^a   Pedersen, Finn Skou ^b  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

IFN; Mx; Rhabdovirus; RNA interference; Target control

Indexed keywords

INTERFERON; MESSENGER RNA; SMALL INTERFERING RNA; VIRUS GLYCOPROTEIN; VIRUS RNA; ANTIVIRUS AGENT; GUANINE NUCLEOTIDE BINDING PROTEIN; MYXOVIRUS RESISTANCE PROTEINS;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; RHABDOVIRUS; RNA DEGRADATION; UPREGULATION; VIROGENESIS; VIRUS INHIBITION; ANIMAL; BIOSYNTHESIS; CELL LINE; FISH; GENETICS; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SENSITIVITY AND SPECIFICITY; VIRUS REPLICATION;

EUKARYOTA; RHABDOVIRIDAE;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; FISHES; GTP-BINDING PROTEINS; INTERFERONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RHABDOVIRIDAE; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; SENSITIVITY AND SPECIFICITY; UP-REGULATION; VIRUS REPLICATION;

EID: 33745676386     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.01.009     Document Type: Article

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