HPA axis dysregulation in mice overexpressing corticotropin releasing hormone

Biological Psychiatry

Volumn 51, Issue 11, 2002, Pages 875-881

  Groenink, Lucianne ^a,d   Dirks, Anneloes ^a   Verdouw, P Monika ^a   Schipholt, Marlies Lutje ^a   Veening, Jan G ^b   Van Der Gugten, Jan ^a   Olivier, Berend ^a,c  

^a UTRECHT UNIVERSITY   (Netherlands)

^b RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Corticosterone; CRF; Dexamethasone suppression test; HPA axis; Major depressive disorder; Transgenic mice

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DEXAMETHASONE;

ADRENAL GLAND; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DEXAMETHASONE SUPPRESSION TEST; HORMONE RELEASE; HORMONE SYNTHESIS; HYPERTROPHY; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; MOUSE; MOUSE STRAIN; NEGATIVE FEEDBACK; NONHUMAN; PHYSICAL STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; WEIGHT; WILD TYPE;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; CORTICOTROPIN-RELEASING HORMONE; GENE EXPRESSION REGULATION; GENOTYPE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MICE; MICE, TRANSGENIC; PITUITARY-ADRENAL SYSTEM; STRESS;

EID: 0036603584     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(02)01334-3     Document Type: Article

References (52)

1. Overexpression of the neural growth-associated protein GAP-453 induces nerve sprouting in the adult nervous system of transgenic mice
2. Corticotropin-releasing hormone (CRH) directly stimulates corticosterone secretion by the rat adrenal gland
3. Effects of cortisol treatment on brain and adrenal corticotropin-releasing hormone (CRH) content and other parameters regulated by CRH
4. Cerebrospinal fluid neuropeptides in mood disorder and dementia
5. Endocrine profile and neuroendocrine challenge tests in transgenic mice expressing antisense RNA against the glucocorticoid receptor
6. Circadian rhythm of melatonin, corticosterone and phagocytosis: Effect of stress
7. Non-invasive, quantitative assessment of the anatomical phenotype of corticotropin-releasing factor-overexpressing mice by MRI
8. Clinical applications of the dexamethasone suppression test for endogenous depression
9. The dexamethasone suppression test for melancholia
10. The neuroendocrinology of depression and chronic stress
11. The concepts of stress and stress system disorders - Overview of physical and behavioral homeostasis
12. Dexamethasone suppression of corticosteroid secretion: Evaluation of the site of action by receptor measures and functional studies
13. Animal models of CRH excess and CRH receptor deficiency display altered adaptations to stress
14. Repeated stress-induced activation of corticotropin-releasing factor neurons enhances vasopressin stores and colocalization with corticotropin-releasing factor in the median eminence of rats
15. Overexpression of corticotropin-releasing hormone in transgenic mice and chronic stress-like autonomic and physiological alterations
16. Reduced startle reactivity and plasticity in transgenic mice overexpressing corticotropin-releasing hormone
17. Salivary cortisol levels and their correlation with plasma ACTH levels in depressed patients before and after the DST
18. Psychological stress increases hippocampal mineralocorticoid receptor levels: Involvement of corticotropin-releasing hormone
19. Neuropeptides and the hypothalamicpituitary-adrenocortical (HPA) system: Review of recent research strategies in depression
20. Regulation of pituitary corticotropin releasing hormone (CRH) receptors by CRH: Interaction with vasopressin
21. CRF receptor regulation and sensitization of ACTH responses to acute ether stress during chronic intermittent immobilization stress
22. Splanchnicotomy increases adrenal sensitivity to ACTH in nonstressed rats
23. The central mechanism of hypothalamic-pituitary-adrenocortical system hyperfunction in depressed patients
24. Cerebrospinal fluid immunoreactive corticotropin-releasing hormone and adrenocorticotropin secretion in Cushing's disease and major depression: Potential clinical implications
25. Prenatal stress alters circadian activity of hypothalamo-pituitary- adrenal axis and hippocampal corticosteroid receptors in adult rats of both genders
26. Modulation of basal and corticotropin-releasing factor-stimulated proopiomelanocortin gene expression by vasopressin in rat anterior pituitary
27. Source of corticotropin-releasing hormone-like innervation of the adrenal glands of fetal and postnatal sheep
28. Regulation of serotonin(1A), glucocorticoid, and mineralocorticoid receptor in rat and human hippocampus: Implications for the neurobiology of depression
29. Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation
30. Penetration of dexamethasone into brain glucocorticoid targets is enhanced in mdr1A P-glycoprotein knockout mice
31. Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice
32. Expression of Thy-1 in the nervous system of the rat and mouse
33. Adrenal gland enlargement in major depression. A computed tomographic study
34. Reduced corticotropin releasing factor binding sites in the frontal cortex of suicide victims
35. Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients
36. Differences in plasma ACTH and cortisol between depressed patients and normal controls
37. Cerebrospinal fluid corticotropin-releasing hormone, vasopressin, and oxytocin concentrations in treated patients with major depression and controls
38. Corticotropin-releasing hormone-like axons in the adrenal glands of fetal and postnatal sheep
39. Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients
40. Adrenal gland volume in major depression. Increase during the depressive episode and decrease with successful treatment
41. Vasopressin and the regulation of hypothalamic-pituitary-adrenal axis function: Implications for the pathophysiology of depression
42. Development of Cushing's syndrome in corticotropin-releasing factor transgenic mice
43. Effects of antidepressant treatment on corticotropin-induced cortisol responses in patients with melancholic depression
44. Rat corticotropin-releasing hormone gene: Sequence and tissue-specific expression
45. Physiological role of corticotropin-releasing factor in the control of adrenocorticotropin-mediated corticosterone release from the rat adrenal gland
46. Changes in CRH-expression and in stress-related FOS-IR in transgenic mice over-expressing CRH
47. Tissue-specific control elements of the Thy-1 gene
48. The effect of repeated human corticotropin releasing hormone administration on dexamethasone suppressed pituitary adrenocortical activity in healthy subjects
49. Neuron-specific transgene expression of Bcl-XL but not Bcl-2 genes reduced lesion size after permanent middle cerebral artery occlusion in mice
50. Pronounced and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism and corticotropin-releasing hormone
51. Cortisol regulation in posttraumatic stress disorder and major depression: A chronobiological analysis
52. Hormonal evidence for altered responsiveness to social stress in major depression