메뉴 건너뛰기




Volumn 27, Issue 1, 2005, Pages 39-48

Caloric restriction versus drug therapy to delay the onset of aging diseases and extend life

Author keywords

Blood pressure; Calorie restriction mimetics; Cardiovascular disease; Cholesterol; Lifespan; Medications

Indexed keywords

3 HYDROXY 3 METHYLGLUTARYL COENZYME A; ACETYLSALICYLIC ACID; ALDOSTERONE; ANGIOTENSINOGEN; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; BIGUANIDE DERIVATIVE; C REACTIVE PROTEIN; CARNOSINE; DEOXYGLUCOSE; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FOLIC ACID; GLUCOSE; GROWTH HORMONE; HOMOCYSTEINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INSULIN; LEVACECARNINE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MELATONIN; METFORMIN; PRASTERONE; RENIN; SELEGILINE; SOMATOMEDIN C; THIOCTIC ACID; TRIACYLGLYCEROL; UBIDECARENONE; XENOBIOTIC AGENT;

EID: 33745667035     PISSN: 01619152     EISSN: 15744647     Source Type: Journal    
DOI: 10.1007/s11357-005-3284-4     Document Type: Review
Times cited : (14)

References (114)
  • 1
    • 0242552333 scopus 로고    scopus 로고
    • Effects of exogenous melatonin - A review
    • Anisimov VN (2003a) Effects of exogenous melatonin - a review. Toxicol Pathol 31: 589-603
    • (2003) Toxicol Pathol , vol.31 , pp. 589-603
    • Anisimov, V.N.1
  • 2
    • 0142186132 scopus 로고    scopus 로고
    • Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention
    • Anisimov VN (2003b) Insulin/IGF-1 signaling pathway driving aging and cancer as a target for pharmacological intervention. Exp Gerontol 38: 1041-1049
    • (2003) Exp Gerontol , vol.38 , pp. 1041-1049
    • Anisimov, V.N.1
  • 3
    • 0344394514 scopus 로고    scopus 로고
    • Insulin and longevity: Antidiabetic biguanides as geroprotectors
    • Anisimov VN, Semenchenko AV and Yashin AI (2003a) Insulin and longevity: antidiabetic biguanides as geroprotectors. Biogerontology 4: 297-307
    • (2003) Biogerontology , vol.4 , pp. 297-307
    • Anisimov, V.N.1    Semenchenko, A.V.2    Yashin, A.I.3
  • 5
    • 0142052858 scopus 로고    scopus 로고
    • Insulin/IGF-1-signaling pathway: An evolutionarily conserved mechanism of longevity from yeast to humans
    • Barbieri M, Bonafe M, Franceschi C and Paolisso G (2003) Insulin/IGF-1-signaling pathway: an evolutionarily conserved mechanism of longevity from yeast to humans. Am J Physiol: Endocrinol Metab 285: E1064-E1071
    • (2003) Am J Physiol: Endocrinol Metab , vol.285
    • Barbieri, M.1    Bonafe, M.2    Franceschi, C.3    Paolisso, G.4
  • 6
    • 85053097739 scopus 로고
    • Dietary restriction and life extension - Biological mechanisms
    • Moment GB (ed) CRC Press, Boca Raton, FL
    • Barrows CH Jr and Kokkonen GC (1982) Dietary restriction and life extension - biological mechanisms. In: Moment GB (ed) Nutritional Approaches to Aging Research, pp 219-243. CRC Press, Boca Raton, FL
    • (1982) Nutritional Approaches to Aging Research , pp. 219-243
    • Barrows Jr., C.H.1    Kokkonen, G.C.2
  • 8
    • 20644432398 scopus 로고
    • Nutrition, onset of disease, and longevity in the rat
    • Berg BN and Simms HS (1965) Nutrition, onset of disease, and longevity in the rat. Can Med Assoc J 93: 911-913
    • (1965) Can Med Assoc J , vol.93 , pp. 911-913
    • Berg, B.N.1    Simms, H.S.2
  • 9
    • 0029968341 scopus 로고    scopus 로고
    • Is there a fountain of youth? a review of current life extension strategies
    • Bernarducci MP and Owens NJ (1996) Is there a fountain of youth? A review of current life extension strategies. Pharmacotherapy 16: 183-200
    • (1996) Pharmacotherapy , vol.16 , pp. 183-200
    • Bernarducci, M.P.1    Owens, N.J.2
  • 10
    • 0037338615 scopus 로고    scopus 로고
    • Mortality and morbidity in laboratory maintained Rhesus monkeys and effects of long-term dietary restriction
    • Bodkin NL, Alexander TM, Ortmeyer HK, Johnson E and Hansen BC (2003) Mortality and morbidity in laboratory maintained Rhesus monkeys and effects of long-term dietary restriction. J Gerontol Biol Sci 58A: 212-221
    • (2003) J Gerontol Biol Sci , vol.58 A , pp. 212-221
    • Bodkin, N.L.1    Alexander, T.M.2    Ortmeyer, H.K.3    Johnson, E.4    Hansen, B.C.5
  • 12
    • 0007256960 scopus 로고
    • Brain ageing and neurodegenerative diseases: A major public health issue of the 21st century
    • Broe GA and Creasey H (1995) Brain ageing and neurodegenerative diseases: a major public health issue of the 21st century. Perspect Hum Biol 1: 53-58
    • (1995) Perspect Hum Biol , vol.1 , pp. 53-58
    • Broe, G.A.1    Creasey, H.2
  • 14
    • 0036233996 scopus 로고    scopus 로고
    • Models of growth hormone and IGF-1 deficiency: Application to studies of aging processes and life-span determination
    • Carter CS, Ramsey MM, Ingram RL, Cashion AB, Cefalu WT, Wang ZQ and Sonntag WE (2002) Models of growth hormone and IGF-1 deficiency: application to studies of aging processes and life-span determination. J Gerontol 57: B177-B188
    • (2002) J Gerontol , vol.57
    • Carter, C.S.1    Ramsey, M.M.2    Ingram, R.L.3    Cashion, A.B.4    Cefalu, W.T.5    Wang, Z.Q.6    Sonntag, W.E.7
  • 15
    • 0036774790 scopus 로고    scopus 로고
    • Medicine at the medical center then and now: One hundred years of progress
    • Cooper MR, Stewart DC, Kahl FR, Brown WM and Cordell AR (2002) Medicine at the medical center then and now: one hundred years of progress. South Med J 95: 1113-1121
    • (2002) South Med J , vol.95 , pp. 1113-1121
    • Cooper, M.R.1    Stewart, D.C.2    Kahl, F.R.3    Brown, W.M.4    Cordell, A.R.5
  • 16
    • 1842732174 scopus 로고    scopus 로고
    • Temporal linkage between the phenotypic and genomic responses to caloric restriction
    • USA
    • Dhahbi JM, Kim H-J, Mote PL, Beaver RJ and Spindler SR (2004) Temporal linkage between the phenotypic and genomic responses to caloric restriction. Proc Natl Acad Sci USA 101: 5524-5529
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 5524-5529
    • Dhahbi, J.M.1    Kim, H.-J.2    Mote, P.L.3    Beaver, R.J.4    Spindler, S.R.5
  • 17
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group (2002) Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 348: 393-403
    • (2002) N Engl J Med , vol.348 , pp. 393-403
  • 18
    • 0032808522 scopus 로고    scopus 로고
    • Weight loss due to energy restriction suppresses cholesterol biosynthesis in overweight, mildly hypercholesterolemic men
    • Di Buono M, Hannah JS, Katzel LI and Jones PJ (1999) Weight loss due to energy restriction suppresses cholesterol biosynthesis in overweight, mildly hypercholesterolemic men. J Nutr 129: 1545-1548
    • (1999) J Nutr , vol.129 , pp. 1545-1548
    • Di Buono, M.1    Hannah, J.S.2    Katzel, L.I.3    Jones, P.J.4
  • 19
    • 3042700097 scopus 로고    scopus 로고
    • Mortality in relation to smoking: 50 Years' observations on male British doctors
    • Doll R, Peto R, Boreham J and Sutherland I (2004) Mortality in relation to smoking: 50 years' observations on male British doctors. BMJ 326: 1519-1528
    • (2004) BMJ , vol.326 , pp. 1519-1528
    • Doll, R.1    Peto, R.2    Boreham, J.3    Sutherland, I.4
  • 20
    • 0030727705 scopus 로고    scopus 로고
    • Dietary restriction reduces insulin-like growth factor 1 levels, which modulates apoptosis, cell proliferation, and tumor progression in p53 deficient mice
    • Dunn SE, Kari FW, French J, Leininger JR, Travlos G, Wilson R and Barrett JC (1997) Dietary restriction reduces insulin-like growth factor 1 levels, which modulates apoptosis, cell proliferation, and tumor progression in p53 deficient mice. Cancer Res 57: 4667-4672
    • (1997) Cancer Res , vol.57 , pp. 4667-4672
    • Dunn, S.E.1    Kari, F.W.2    French, J.3    Leininger, J.R.4    Travlos, G.5    Wilson, R.6    Barrett, J.C.7
  • 22
    • 0037234110 scopus 로고    scopus 로고
    • Food restriction, pituitary hormones and ageing
    • Everitt AV (2003) Food restriction, pituitary hormones and ageing. Biogerontology 4: 47-50
    • (2003) Biogerontology , vol.4 , pp. 47-50
    • Everitt, A.V.1
  • 23
    • 16544370905 scopus 로고    scopus 로고
    • Can calorie restriction prolong life?
    • Everitt AV (2004) Can calorie restriction prolong life? Med Today 5: 91-92
    • (2004) Med Today , vol.5 , pp. 91-92
    • Everitt, A.V.1
  • 24
    • 33745660175 scopus 로고
    • The effect of chronic lung disease on the course of ageing in the male rat
    • Everitt AV and Cavanagh LM (1963) The effect of chronic lung disease on the course of ageing in the male rat. Gerontologia 8: 1-15
    • (1963) Gerontologia , vol.8 , pp. 1-15
    • Everitt, A.V.1    Cavanagh, L.M.2
  • 27
    • 2342647592 scopus 로고    scopus 로고
    • Long-term caloric restriction is highly effective in reducing the risk for atherosclerosis in humans
    • USA
    • Fontana L, Meyer TE, Klein S and Holloszy JO (2004) Long-term caloric restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc Natl Acad Sci USA 101: 6659-6663
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 6659-6663
    • Fontana, L.1    Meyer, T.E.2    Klein, S.3    Holloszy, J.O.4
  • 28
    • 0034923359 scopus 로고    scopus 로고
    • Ten years of life: Is it a matter of choice?
    • Fraser GE and Shavlik DJ (2001) Ten years of life: is it a matter of choice? Arch Intern Med 161: 1645-1652
    • (2001) Arch Intern Med , vol.161 , pp. 1645-1652
    • Fraser, G.E.1    Shavlik, D.J.2
  • 29
    • 1842521023 scopus 로고    scopus 로고
    • Management of obesity as a chronic disease: Nonpharmacologic, pharmacologic, and surgical options
    • Fujioka K (2002) Management of obesity as a chronic disease: nonpharmacologic, pharmacologic, and surgical options. Obes Res 10(Suppl 2): 116S-123S
    • (2002) Obes Res , vol.10 , Issue.2 SUPPL.
    • Fujioka, K.1
  • 30
    • 0033669562 scopus 로고    scopus 로고
    • Annual summary of vital statistics: Trends in the health of Americans during the 20th century
    • Guyer B, Freedman MA, Strobino DM and Sondik EJ (2000) Annual summary of vital statistics: trends in the health of Americans during the 20th century. Pediatrics 106: 1307-1317
    • (2000) Pediatrics , vol.106 , pp. 1307-1317
    • Guyer, B.1    Freedman, M.A.2    Strobino, D.M.3    Sondik, E.J.4
  • 31
    • 33745642320 scopus 로고    scopus 로고
    • Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function, while decreasing oxidative stress
    • USA
    • Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll IT, Vinarsky V, Bartholomew C and Ames BN (2002) Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function, while decreasing oxidative stress. Proc Natl Acad Sci USA 123(425): 191-196
    • (2002) Proc Natl Acad Sci , vol.123 , Issue.425 , pp. 191-196
    • Hagen, T.M.1    Liu, J.2    Lykkesfeldt, J.3    Wehr, C.M.4    Ingersoll, I.T.5    Vinarsky, V.6    Bartholomew, C.7    Ames, B.N.8
  • 32
    • 0027437865 scopus 로고
    • Primary prevention of diabetes mellitus by prevention of obesity in monkeys
    • Hansen BC and Bodkin NL (1993) Primary prevention of diabetes mellitus by prevention of obesity in monkeys. Diabetes 42: 1809-1814
    • (1993) Diabetes , vol.42 , pp. 1809-1814
    • Hansen, B.C.1    Bodkin, N.L.2
  • 33
    • 0141720388 scopus 로고    scopus 로고
    • Calorie restriction and aging: Review of the literature and implications for studies in humans
    • Heilbronn LK and Ravussen E (2003) Calorie restriction and aging: review of the literature and implications for studies in humans. Am J Clin Nutr 78: 361-369
    • (2003) Am J Clin Nutr , vol.78 , pp. 361-369
    • Heilbronn, L.K.1    Ravussen, E.2
  • 34
    • 0035885393 scopus 로고    scopus 로고
    • Carnosine the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups
    • Hipkiss AR, Brownson C and Carrier MJ (2001) Carnosine the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups. Mech Ageing Dev 122: 1431-1435
    • (2001) Mech Ageing Dev , vol.122 , pp. 1431-1435
    • Hipkiss, A.R.1    Brownson, C.2    Carrier, M.J.3
  • 35
    • 0031058447 scopus 로고    scopus 로고
    • Mortality rate and longevity of food-restricted exercising male rats: A reevaluation
    • Holloszy JO (1997) Mortality rate and longevity of food-restricted exercising male rats: a reevaluation. J Appl Physiol 82: 399-403
    • (1997) J Appl Physiol , vol.82 , pp. 399-403
    • Holloszy, J.O.1
  • 37
    • 0013072999 scopus 로고    scopus 로고
    • Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans
    • Hursting SD, Lavigne JA, Berrigan D, Perkins SN and Barrett JC (2003) Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 54: 131-152
    • (2003) Annu Rev Med , vol.54 , pp. 131-152
    • Hursting, S.D.1    Lavigne, J.A.2    Berrigan, D.3    Perkins, S.N.4    Barrett, J.C.5
  • 40
    • 0033800397 scopus 로고    scopus 로고
    • Endocrine aspects of ageing in men. Is hormone replacement of benefit?
    • Janssens H (2000) Endocrine aspects of ageing in men. Is hormone replacement of benefit? Eur J Obstet Gynecol Reprod Biol 92: 7-12
    • (2000) Eur J Obstet Gynecol Reprod Biol , vol.92 , pp. 7-12
    • Janssens, H.1
  • 41
    • 0021140445 scopus 로고
    • Declining cardiovascular mortality
    • Kannel WB and Thom TJ (1984) Declining cardiovascular mortality. Circulation 70: 331-336
    • (1984) Circulation , vol.70 , pp. 331-336
    • Kannel, W.B.1    Thom, T.J.2
  • 42
    • 0000221346 scopus 로고
    • Effect of dietary (caloric) restriction on aging, survival, pathology, and toxicology, in pathobiology of the aging rat
    • Keenan KP, Smith PF and Soper KA (1994) Effect of dietary (caloric) restriction on aging, survival, pathology, and toxicology, in pathobiology of the aging rat. Int Life Sci Inst 2: 609-628
    • (1994) Int Life Sci Inst , vol.2 , pp. 609-628
    • Keenan, K.P.1    Smith, P.F.2    Soper, K.A.3
  • 43
    • 0036234704 scopus 로고    scopus 로고
    • Pharmacological interventions in aging and age-associated disorders: Potentials of propargylamines for human use
    • Kitani K, Minami C, Yamamoto T, Kanai S, Ivy GO and Carrillo MC (2000) Pharmacological interventions in aging and age-associated disorders: potentials of propargylamines for human use. Ann NY Acad Sci 959: 295-307
    • (2000) Ann NY Acad Sci , vol.959 , pp. 295-307
    • Kitani, K.1    Minami, C.2    Yamamoto, T.3    Kanai, S.4    Ivy, G.O.5    Carrillo, M.C.6
  • 44
    • 0029108666 scopus 로고
    • Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory endpoints
    • Lane MA, Ball SS, Ingram DK, Cutler RG, Engel J, Read V and Roth GS (1995) Diet restriction in rhesus monkeys lowers fasting and glucose-stimulated glucoregulatory endpoints. Am J Physiol 268: E941-E948
    • (1995) Am J Physiol , vol.268
    • Lane, M.A.1    Ball, S.S.2    Ingram, D.K.3    Cutler, R.G.4    Engel, J.5    Read, V.6    Roth, G.S.7
  • 45
    • 0033377625 scopus 로고    scopus 로고
    • Calorie restriction in nonhuman primates: Effects on diabetes and cardiovascular risk
    • Lane MA, Ingram DK and Roth GS (1999) Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular risk. Toxicol Sci 52(2 Suppl): 41-48
    • (1999) Toxicol Sci , vol.52 , Issue.2 SUPPL. , pp. 41-48
    • Lane, M.A.1    Ingram, D.K.2    Roth, G.S.3
  • 47
    • 0037111862 scopus 로고    scopus 로고
    • Caloric restriction and aging in primates: Relevance to humans and possible CR mimetics
    • Lane MA, Mattison J, Ingram DK and Roth GS (2002) Caloric restriction and aging in primates: relevance to humans and possible CR mimetics. Microsc Res Tech 59: 335-338
    • (2002) Microsc Res Tech , vol.59 , pp. 335-338
    • Lane, M.A.1    Mattison, J.2    Ingram, D.K.3    Roth, G.S.4
  • 48
    • 2442428282 scopus 로고    scopus 로고
    • Effects of long-term diet restriction on aging and longevity in primates remains uncertain
    • Lane MA, Mattison JA, Roth GS, Brandt LJ and Ingram DK (2004) Effects of long-term diet restriction on aging and longevity in primates remains uncertain. J Gerontol Biol Sci 59A: 405-407
    • (2004) J Gerontol Biol Sci , vol.59 A , pp. 405-407
    • Lane, M.A.1    Mattison, J.A.2    Roth, G.S.3    Brandt, L.J.4    Ingram, D.K.5
  • 49
    • 0037490080 scopus 로고    scopus 로고
    • Quantifying effects of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: Systematic review and meta-analysis
    • Law MR, Wald NJ and Rudnicka AR (2003a) Quantifying effects of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ 326: 1423-1427
    • (2003) BMJ , vol.326 , pp. 1423-1427
    • Law, M.R.1    Wald, N.J.2    Rudnicka, A.R.3
  • 50
    • 0037490085 scopus 로고    scopus 로고
    • Value of low dose combination treatment with blood pressure lowering drugs: Analysis of 354 randomised trials
    • Law MR, Wald NJ, Morris JK and Jordan RE (2003b) Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials. BMJ 326: 1427-1431
    • (2003) BMJ , vol.326 , pp. 1427-1431
    • Law, M.R.1    Wald, N.J.2    Morris, J.K.3    Jordan, R.E.4
  • 51
    • 0037018753 scopus 로고    scopus 로고
    • Hepatic pseudocapillarisation and atherosclerosis in ageing
    • Le Couteur DG, Fraser R, Cogger VC and McLean AJ (2002a) Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet 359: 1612-1615
    • (2002) Lancet , vol.359 , pp. 1612-1615
    • Le Couteur, D.G.1    Fraser, R.2    Cogger, V.C.3    McLean, A.J.4
  • 52
    • 0036375516 scopus 로고    scopus 로고
    • Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease
    • Le Couteur DG, Muller M, Yang M, Mellick GD and McLean AJ (2002b) Age-environment and gene-environment interactions in the pathogenesis of Parkinson's disease. Rev Environ Health 17: 51-64
    • (2002) Rev Environ Health , vol.17 , pp. 51-64
    • Le Couteur, D.G.1    Muller, M.2    Yang, M.3    Mellick, G.D.4    McLean, A.J.5
  • 53
    • 13244297157 scopus 로고    scopus 로고
    • The hepatic sinusoid in aging and cirrhosis: Effects on hepatic substrate disposition and drug clearance
    • Le Couteur DG, Fraser R, Hilmer SN, Rivory LP and McClean AJ (2005) The hepatic sinusoid in aging and cirrhosis: effects on hepatic substrate disposition and drug clearance. Clin Pharmacokinet 44: 187-200
    • (2005) Clin Pharmacokinet , vol.44 , pp. 187-200
    • Le Couteur, D.G.1    Fraser, R.2    Hilmer, S.N.3    Rivory, L.P.4    McClean, A.J.5
  • 55
    • 0033394933 scopus 로고    scopus 로고
    • Lesion biomarkers of aging in B6C3F1 hybrid mice
    • Lipman RD, Dallah GE and Bronson RT (1999) Lesion biomarkers of aging in B6C3F1 hybrid mice. J Gerontol 54A: B466-B477
    • (1999) J Gerontol , vol.54 A
    • Lipman, R.D.1    Dallah, G.E.2    Bronson, R.T.3
  • 56
    • 0037470488 scopus 로고    scopus 로고
    • Evolutionary medicine: From dwarf model systems to healthy centenarians?
    • Longo VD and Finch CE (2003) Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299: 1342-1346
    • (2003) Science , vol.299 , pp. 1342-1346
    • Longo, V.D.1    Finch, C.E.2
  • 57
    • 0029014276 scopus 로고
    • Dietary restriction
    • Masoro EJ (1995) Dietary restriction. Exp Gerontol 30: 291-298
    • (1995) Exp Gerontol , vol.30 , pp. 291-298
    • Masoro, E.J.1
  • 62
    • 0002458132 scopus 로고
    • The effect of retarded growth upon the length of the lifespan and ultimate body size
    • McCay CM, Crowell MF and Maynard LA (1935) The effect of retarded growth upon the length of the lifespan and ultimate body size. J Nutr 10: 63-79
    • (1935) J Nutr , vol.10 , pp. 63-79
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 63
    • 33745641402 scopus 로고    scopus 로고
    • Hitting a century: Centenarians in Australia
    • McCormack J (2000) Hitting a century: centenarians in Australia. Aust J Ageing 19: 75-80
    • (2000) Aust J Ageing , vol.19 , pp. 75-80
    • McCormack, J.1
  • 64
    • 0027360855 scopus 로고
    • Actual causes of death in the United States
    • McGinnis M and Foege WH (1993) Actual causes of death in the United States. JAMA 270: 2207-2212
    • (1993) JAMA , vol.270 , pp. 2207-2212
    • McGinnis, M.1    Foege, W.H.2
  • 65
    • 2642572647 scopus 로고    scopus 로고
    • Aging biology and geriatric clinical pharmacology
    • McLean A and Le Couteur DG (2004) Aging biology and geriatric clinical pharmacology. Pharmacol Rev 56: 163-184
    • (2004) Pharmacol Rev , vol.56 , pp. 163-184
    • McLean, A.1    Le Couteur, D.G.2
  • 66
    • 0033765019 scopus 로고    scopus 로고
    • Is there a link between pharmaceutical consumption and improved health in OECD countries?
    • Miller RD Jr and Frech HE (2000) Is there a link between pharmaceutical consumption and improved health in OECD countries? Pharmacoeconomics 18(Suppl 1): 33-45
    • (2000) Pharmacoeconomics , vol.18 , Issue.1 SUPPL. , pp. 33-45
    • Miller Jr., R.D.1    Frech, H.E.2
  • 67
    • 1542347858 scopus 로고    scopus 로고
    • Actual causes of death in the United States, 2000
    • Mokdad AH, Marks JS, Stroup DF and Gerberding JL (2004) Actual causes of death in the United States, 2000. JAMA 291: 1263-1264
    • (2004) JAMA , vol.291 , pp. 1263-1264
    • Mokdad, A.H.1    Marks, J.S.2    Stroup, D.F.3    Gerberding, J.L.4
  • 68
    • 0032757405 scopus 로고    scopus 로고
    • Growth hormone: Fountain of youth or death hormone?
    • Morley JE (1999) Growth hormone: fountain of youth or death hormone? J Am Geriat Soc 47: 1475-1476
    • (1999) J Am Geriat Soc , vol.47 , pp. 1475-1476
    • Morley, J.E.1
  • 69
    • 0034024321 scopus 로고    scopus 로고
    • Diabetes mellitus: A major disease of older persons
    • Morley JE (2000) Diabetes mellitus: a major disease of older persons. J Gerontol Med Sci 55A: M255-M256
    • (2000) J Gerontol Med Sci , vol.55 A
    • Morley, J.E.1
  • 70
    • 2442424038 scopus 로고    scopus 로고
    • Is the hormonal fountain of youth drying up?
    • Morley JE (2004) Is the hormonal fountain of youth drying up? J Gerontol Med Sci 59A: 458-460
    • (2004) J Gerontol Med Sci , vol.59 A , pp. 458-460
    • Morley, J.E.1
  • 72
    • 33745638843 scopus 로고    scopus 로고
    • Center for Disease Control and Prevention, Natl Ctr Health Stats, Hyattsville, MD
    • National Vital Statistics Reports (2004) Center for Disease Control and Prevention, Vol 52, # 13. Natl Ctr Health Stats, Hyattsville, MD
    • (2004) National Vital Statistics Reports , vol.52 , Issue.13
  • 73
    • 0037198047 scopus 로고    scopus 로고
    • Mechanism of action of anti-aging DHEA-S and the replacement of DHEA-S
    • Nawata H, Yanese T, Goto K, Okabe T and Ashida K (2002) Mechanism of action of anti-aging DHEA-S and the replacement of DHEA-S. Mech Ageing Dev 123: 1101-1106
    • (2002) Mech Ageing Dev , vol.123 , pp. 1101-1106
    • Nawata, H.1    Yanese, T.2    Goto, K.3    Okabe, T.4    Ashida, K.5
  • 74
    • 33745649932 scopus 로고    scopus 로고
    • Tiffen R and Gittens R (eds) How Australia Compares, Cambridge University Press, Cambridge, UK
    • OECD Health Data 2003 (2004) In: Tiffen R and Gittens R (eds) How Australia Compares, pp 210-211. Cambridge University Press, Cambridge, UK
    • (2004) OECD Health Data 2003 , pp. 210-211
  • 75
    • 0027475199 scopus 로고
    • The association of changes in physical-activity level and other lifestyle characteristics with mortality among men
    • Paffenbarger RS, Hyde RT, Wing AL, Lee I-M, Jung DL and Kampert JB (1993) The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 328: 538-545
    • (1993) N Engl J Med , vol.328 , pp. 538-545
    • Paffenbarger, R.S.1    Hyde, R.T.2    Wing, A.L.3    Lee, I.-M.4    Jung, D.L.5    Kampert, J.B.6
  • 77
    • 0037422846 scopus 로고    scopus 로고
    • NEDCOM, the Netherlands Epidemiology and Demography Comparison of Morbidity Research Group. Obesity in adulthood and its consequences for life expectancy: A life-table analysis
    • Peeters A, Barendregt JJ, Willekens F, Mackenbach JP, Al Mamum A and Bonneux L (2003) NEDCOM, The Netherlands Epidemiology and Demography Comparison of Morbidity Research Group. Obesity in adulthood and its consequences for life expectancy: a life-table analysis. Ann Intern Med 138: 24-32
    • (2003) Ann Intern Med , vol.138 , pp. 24-32
    • Peeters, A.1    Barendregt, J.J.2    Willekens, F.3    Mackenbach, J.P.4    Al Mamum, A.5    Bonneux, L.6
  • 78
    • 0037463821 scopus 로고    scopus 로고
    • Effect of 1-year oral administration of dehydroepi-androsterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: A double blind placebo-controlled trial
    • Percheron G, Hogrel JY, Donot-Ledunois S, Fayet G, Foret G, Baulieu EE, Fardeau M and Marini JF (2003) Effect of 1-year oral administration of dehydroepi-androsterone to 60- to 80-year-old individuals on muscle function and cross-sectional area: a double blind placebo-controlled trial. Arch Intern Med 163: 720-727
    • (2003) Arch Intern Med , vol.163 , pp. 720-727
    • Percheron, G.1    Hogrel, J.Y.2    Donot-Ledunois, S.3    Fayet, G.4    Foret, G.5    Baulieu, E.E.6    Fardeau, M.7    Marini, J.F.8
  • 79
    • 0038456954 scopus 로고    scopus 로고
    • Diabetes and hypertension - Double trouble
    • Phillips PJ, Popplewell P and Wing L (2003) Diabetes and hypertension - double trouble. Med Today 4: 32-46
    • (2003) Med Today , vol.4 , pp. 32-46
    • Phillips, P.J.1    Popplewell, P.2    Wing, L.3
  • 80
    • 0029037649 scopus 로고
    • Pathophysiology of insulin resistance in human disease
    • Reaven GH (1995) Pathophysiology of insulin resistance in human disease. Physiol Rev 75: 473-485
    • (1995) Physiol Rev , vol.75 , pp. 473-485
    • Reaven, G.H.1
  • 81
    • 1942436958 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF)-1, IGF binding protein-3, and cancer risk: Systematic review and meta-regression analysis
    • Renehan AG, Zwahlen M, Minder C, O'Dwyer ST, Shalet SM and Egger M (2004) Insulin-like growth factor (IGF)-1, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 363: 1346-1353
    • (2004) Lancet , vol.363 , pp. 1346-1353
    • Renehan, A.G.1    Zwahlen, M.2    Minder, C.3    O'Dwyer, S.T.4    Shalet, S.M.5    Egger, M.6
  • 83
    • 1242274344 scopus 로고    scopus 로고
    • Pharmacoepidemiology and disability in older adults: Can medications slow the age-related decline in physical functions?
    • Savo A, Maiorano PM, Onder G and Bernabei R (2003) Pharmacoepidemiology and disability in older adults: can medications slow the age-related decline in physical functions? Expert Opin Pharmacother 5: 407-413
    • (2003) Expert Opin Pharmacother , vol.5 , pp. 407-413
    • Savo, A.1    Maiorano, P.M.2    Onder, G.3    Bernabei, R.4
  • 85
    • 0038380473 scopus 로고    scopus 로고
    • Life span extension by reduction of growth hormone-insulin like growth factor-1 axis: Relation to calorie restriction
    • Shimokawa I, Higami Y, Tsuchiya T, Otani H, Komatsu T, Chiba T and Yamaza H (2003) Life span extension by reduction of growth hormone-insulin like growth factor-1 axis: relation to calorie restriction. FASEB J 17: 1108-1109
    • (2003) FASEB J , vol.17 , pp. 1108-1109
    • Shimokawa, I.1    Higami, Y.2    Tsuchiya, T.3    Otani, H.4    Komatsu, T.5    Chiba, T.6    Yamaza, H.7
  • 86
    • 33745669545 scopus 로고
    • Longevity in relation to lesion onset
    • Simms HS and Berg BN (1962) Longevity in relation to lesion onset. Geriatrics 17: 235-242
    • (1962) Geriatrics , vol.17 , pp. 235-242
    • Simms, H.S.1    Berg, B.N.2
  • 88
    • 0033450849 scopus 로고    scopus 로고
    • Pleiotropic effects of growth hormone and insulin-like growth factor (IGF-1) on biological aging: Inferences from moderate caloric-restricted animals
    • Sonntag WE, Lynch CD, Cefalu WT, Ingram RL, Bennett SA, Thornton PL and Khan AS (1999) Pleiotropic effects of growth hormone and insulin-like growth factor (IGF-1) on biological aging: inferences from moderate caloric-restricted animals. J Gerontol 54: B521-B538
    • (1999) J Gerontol , vol.54
    • Sonntag, W.E.1    Lynch, C.D.2    Cefalu, W.T.3    Ingram, R.L.4    Bennett, S.A.5    Thornton, P.L.6    Khan, A.S.7
  • 89
    • 0030941484 scopus 로고    scopus 로고
    • Diet and calorie restriction
    • Sprott RL (1997) Diet and calorie restriction. Exp Gerontol 32: 205-214
    • (1997) Exp Gerontol , vol.32 , pp. 205-214
    • Sprott, R.L.1
  • 90
    • 0021954235 scopus 로고
    • The marked decline in coronary heart disease mortality rates in the United States 1968-1981: Summary of findings and possible explanations
    • Stamler J (1985) The marked decline in coronary heart disease mortality rates in the United States 1968-1981: summary of findings and possible explanations. Cardiology 72: 11-22
    • (1985) Cardiology , vol.72 , pp. 11-22
    • Stamler, J.1
  • 91
    • 4644224498 scopus 로고
    • Nutrition, aging and obesity
    • Rockstein M and Sussman ML (eds) Academic Press, New York
    • Stunkard AJ (1976) Nutrition, aging and obesity. In: Rockstein M and Sussman ML (eds) Nutrition, Longevity and Aging, pp 253-284. Academic Press, New York
    • (1976) Nutrition, Longevity and Aging , pp. 253-284
    • Stunkard, A.J.1
  • 92
    • 0025353476 scopus 로고
    • Changes in risk factors and the decline in mortality from cardiovascular disease. The Framingham Heart Study
    • Sytkowski PA, Kannel WB and D'Agostini RB (1990) Changes in risk factors and the decline in mortality from cardiovascular disease. The Framingham Heart Study. N Engl J Med 322: 1635-1641
    • (1990) N Engl J Med , vol.322 , pp. 1635-1641
    • Sytkowski, P.A.1    Kannel, W.B.2    D'Agostini, R.B.3
  • 93
    • 0028355453 scopus 로고
    • Survival, body weight, and spontaneous neoplasms in ad libitum-fed and food-restricted Fischer-344 rats
    • Thurman JD, Bucci TJ, Hart RW and Turturro A (1994) Survival, body weight, and spontaneous neoplasms in ad libitum-fed and food-restricted Fischer-344 rats. Toxicol Pathol 22: 1-9
    • (1994) Toxicol Pathol , vol.22 , pp. 1-9
    • Thurman, J.D.1    Bucci, T.J.2    Hart, R.W.3    Turturro, A.4
  • 94
    • 2442661860 scopus 로고    scopus 로고
    • Hormone replacement therapy in relation to breast carcinoma incidence rate ratios: A prospective Danish cohort study
    • Tjonneland A, Christensen J, Thomsen BL, Olsen A, Overvad K, Ewerts M and Melle L (2004) Hormone replacement therapy in relation to breast carcinoma incidence rate ratios: a prospective Danish cohort study. Cancer 100: 2326-2337
    • (2004) Cancer , vol.100 , pp. 2326-2337
    • Tjonneland, A.1    Christensen, J.2    Thomsen, B.L.3    Olsen, A.4    Overvad, K.5    Ewerts, M.6    Melle, L.7
  • 98
    • 77049302902 scopus 로고
    • La dieta de hombre a dias alternos in a la alimentacion de los viejos
    • Vallejo EA (1957) La dieta de hombre a dias alternos in a la alimentacion de los viejos. Rev Clin Exp 63: 25-49
    • (1957) Rev Clin Exp , vol.63 , pp. 25-49
    • Vallejo, E.A.1
  • 101
    • 11444254799 scopus 로고    scopus 로고
    • Statins - Is there no end to their usefulness?
    • Wainwright C (2005) Statins - is there no end to their usefulness? Cardiovasc Res 65: 296-298
    • (2005) Cardiovasc Res , vol.65 , pp. 296-298
    • Wainwright, C.1
  • 102
    • 0038165393 scopus 로고    scopus 로고
    • A strategy to reduce cardiovascular disease by more than 80%
    • Wald NJ and Law MR (2003) A strategy to reduce cardiovascular disease by more than 80%. BMJ 326: 1419-1423
    • (2003) BMJ , vol.326 , pp. 1419-1423
    • Wald, N.J.1    Law, M.R.2
  • 103
    • 0026439948 scopus 로고
    • The calorically restricted low-fat, nutrient dense diet in Biosphere 2 significantly lowers blood glucose, total leukocyte count, cholesterol and blood pressure in humans
    • USA
    • Walford RL, Harris SB and Gunion MW (1992) The calorically restricted low-fat, nutrient dense diet in Biosphere 2 significantly lowers blood glucose, total leukocyte count, cholesterol and blood pressure in humans. Proc Natl Acad Sci USA 98: 11533-11537
    • (1992) Proc Natl Acad Sci , vol.98 , pp. 11533-11537
    • Walford, R.L.1    Harris, S.B.2    Gunion, M.W.3
  • 104
    • 0036265323 scopus 로고    scopus 로고
    • Calorie restriction in Biosphere 2: Alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period
    • Walford RL, Mock D, Verdery R and MacCallum T (2002) Calorie restriction in Biosphere 2: alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period. J Gerontol Biol Sci 57A: B211-B224
    • (2002) J Gerontol Biol Sci , vol.57 A
    • Walford, R.L.1    Mock, D.2    Verdery, R.3    MacCallum, T.4
  • 105
    • 0028435096 scopus 로고
    • The frequency and severity of adverse drug reactions in elderly people
    • Walker J and Wynne H (1994) The frequency and severity of adverse drug reactions in elderly people. Age Ageing 23: 255-259
    • (1994) Age Ageing , vol.23 , pp. 255-259
    • Walker, J.1    Wynne, H.2
  • 106
    • 2542449166 scopus 로고    scopus 로고
    • Hormone replacement therapy for the primary prevention of chronic diseases: Recommendation statement from the Canadian Task Force on Preventive Health Care
    • The Canadian Task Force on Preventive Health Care
    • Wathen CN, Feig DS, Feightner JW, Abramson BL and Cheung AM (2004) The Canadian Task Force on Preventive Health Care. Hormone replacement therapy for the primary prevention of chronic diseases: recommendation statement from the Canadian Task Force on Preventive Health Care. Can Med Assoc J 170: 1535-1537
    • (2004) Can Med Assoc J , vol.170 , pp. 1535-1537
    • Wathen, C.N.1    Feig, D.S.2    Feightner, J.W.3    Abramson, B.L.4    Cheung, A.M.5
  • 107
    • 0031549576 scopus 로고    scopus 로고
    • Caloric intake and aging
    • Weindruch R and Sohal RS (1997) Caloric intake and aging. N Engl J Med 337: 986-994
    • (1997) N Engl J Med , vol.337 , pp. 986-994
    • Weindruch, R.1    Sohal, R.S.2
  • 109
    • 16544361917 scopus 로고
    • Prospects for retarding human aging by dietary restriction
    • Chapter 6. Weindruch R and Walford RL (eds) Charles C. Thomas, Springfield, IL
    • Weindruch R and Walford RL (1988b) Prospects for retarding human aging by dietary restriction. Chapter 6. In: Weindruch R and Walford RL (eds) Retardation of Aging and Disease by Dietary Restriction, pp 295-337. Charles C. Thomas, Springfield, IL
    • (1988) Retardation of Aging and Disease by Dietary Restriction , pp. 295-337
    • Weindruch, R.1    Walford, R.L.2
  • 111
    • 0036291466 scopus 로고    scopus 로고
    • Glycemic index, glycemic load, and risk of type 2 diabetes
    • Willett W, Manson JA and Liu S (2002) Glycemic index, glycemic load, and risk of type 2 diabetes. Am J Clin Nutr 76(Suppl): 274S-280S
    • (2002) Am J Clin Nutr , vol.76 , Issue.SUPPL.
    • Willett, W.1    Manson, J.A.2    Liu, S.3
  • 112
    • 0033653973 scopus 로고    scopus 로고
    • Demography of longevity: Past, present, and future trends
    • Wilmoth JR (2000) Demography of longevity: past, present, and future trends. Exp Gerontol 35: 1111-1229
    • (2000) Exp Gerontol , vol.35 , pp. 1111-1229
    • Wilmoth, J.R.1
  • 114
    • 0020059410 scopus 로고
    • Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: Longevity, growth, lean body mass and disease
    • Yu BP, Masoro EJ, Murata I, Bertrand HA and Lynd FT (1982) Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: longevity, growth, lean body mass and disease. J Gerontol 37: 130-141
    • (1982) J Gerontol , vol.37 , pp. 130-141
    • Yu, B.P.1    Masoro, E.J.2    Murata, I.3    Bertrand, H.A.4    Lynd, F.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.