Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver

Life Sciences

Volumn 79, Issue 8, 2006, Pages 737-743

  Ishiguro, Hiroki ^a   Katano, Yoshiaki ^a   Nakano, Isao ^a   Ishigami, Masatoshi ^a   Hayashi, Kazuhiko ^a   Honda, Takashi ^a   Goto, Hidemi ^a   Bajotto, Gustavo ^b   Maeda, Ken ^b   Shimomura, Yoshiharu ^b  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGOYA INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

4E BP1; Branched chain keto acid dehydrogenase complex; Clofibrate; eIF; Leucine; mTOR; S6K1

Indexed keywords

2 OXOISOVALERATE DEHYDROGENASE (LIPOAMIDE); BRANCHED CHAIN AMINO ACID; CLOFIBRATE; INITIATION FACTOR 4E BINDING PROTEIN 1; LEUCINE; LIVER ENZYME; MAMMALIAN TARGET OF RAPAMYCIN; S6 KINASE;

AMINO ACID METABOLISM; ANIMAL TISSUE; ARTICLE; ATTENUATION; CATABOLISM; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MALE; NONHUMAN; PREDICTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

3-METHYL-2-OXOBUTANOATE DEHYDROGENASE (LIPOAMIDE); AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; ANTILIPEMIC AGENTS; CARRIER PROTEINS; CLOFIBRATE; LEUCINE; LIVER; MALE; MULTIENZYME COMPLEXES; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN KINASES; RATS; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

EUKARYOTA; MAMMALIA;

EID: 33745662623     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.02.037     Document Type: Article

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