메뉴 건너뛰기




Volumn 128, Issue 25, 2006, Pages 8227-8233

Temperature- and length-dependent energetics of formation for polyalanine helices in water: Assignment of wAla(n, T) and temperature-dependent CD ellipticity standards

Author keywords

[No Author keywords available]

Indexed keywords

ENTHALPY; MOLECULAR STRUCTURE; NITROGEN COMPOUNDS; NUCLEAR MAGNETIC RESONANCE; TEMPERATURE DISTRIBUTION; WATER;

EID: 33745648494     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja060094y     Document Type: Article
Times cited : (37)

References (42)
  • 3
    • 33745642314 scopus 로고    scopus 로고
    • note
    • i over a particular helical region equals the overall FH for that region.
  • 5
    • 0001887066 scopus 로고    scopus 로고
    • The intrinsic tendency toward α-helix formation
    • Vijayan, M., Yathindra, N., Kolaskar, A. S., Eds.; Indian Academy of Sciences: Bangalore
    • For example: (a) Scheraga, H. A. The Intrinsic Tendency Toward α-Helix Formation. In Perspectives in Structural Biology; Vijayan, M., Yathindra, N., Kolaskar, A. S., Eds.; Indian Academy of Sciences: Bangalore, 1999; pp 275-282.
    • (1999) Perspectives in Structural Biology , pp. 275-282
    • Scheraga, H.A.1
  • 16
    • 33745639072 scopus 로고    scopus 로고
    • note
    • 2CO-) and beta ≡ β-amino-alanine.
  • 24
    • 0036959796 scopus 로고    scopus 로고
    • nc, which has significant advantages: Kemp, D. S. Helv. Chim. Acta 2002, 85, 4392-4423.
    • (2002) Helv. Chim. Acta , vol.85 , pp. 4392-4423
    • Kemp, D.S.1
  • 29
    • 33745647945 scopus 로고    scopus 로고
    • note
    • We employ a fixed ν = 0.048 to assign stabilities of single or paired residues with helical φ, Ψ angles, but to model helical end effects, we have replaced ν by t. A fixed w = 1.108 and a temperature-dependent t of 0.07 (a 45% increase from t = ν = 0.048 at 2 °C) successfully models Table 1 60 °C chemical shifts.
  • 36
    • 33745661732 scopus 로고    scopus 로고
    • note
    • λ.U.T, see the Supporting Information.
  • 41
    • 33745664611 scopus 로고    scopus 로고
    • note
    • n peptides with n > 13 (temperature range 2-60 °C) showed double-slope 222 vs 208 nm parametric plots similar to that of Figure 6b. Three cases with n < 13 showed single-slope plots with slope ranges 2.2-2.3. A brief discussion of these, with an example, appears in the Supporting Information.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.