High-resolution structure of a plasmid-encoded dihydrofolate reductase: Pentagonal network of water molecules in the D2-symmetric active site

Acta Crystallographica Section D: Biological Crystallography

Volumn 62, Issue 7, 2006, Pages 695-706

  Narayana, Narendra ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; SOLVENT; WATER;

ALGORITHM; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; FREEZING; GENETICS; HYDROGEN BOND; KINETICS; METHODOLOGY; PLASMID; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY;

ALGORITHMS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; FREEZING; HYDROGEN BONDING; KINETICS; MODELS, MOLECULAR; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROFOLATE DEHYDROGENASE; THERMODYNAMICS; WATER;

EID: 33745637695     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444906014764     Document Type: Article

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