Dynamic control of allosteric antagonism of leukocyte function antigen-1 and intercellular adhesion molecule-1 interaction

Proteins: Structure, Function and Genetics

Volumn 64, Issue 2, 2006, Pages 376-384

  Nam, Kiyean ^a   Maiorov, Vladimir ^a   Feuston, Bradley ^a   Kearsley, Simon ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

MD (molecular dynamics); MM PB(GB)SA (molecular mechanics Poisson Boltzmann generalized Born surface area); NMA (normal mode analysis)

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1;

ALLOSTERISM; ALPHA HELIX; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL MIGRATION; MATHEMATICAL COMPUTING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; T LYMPHOCYTE;

ALLOSTERIC SITE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 33745591641     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.20999     Document Type: Article

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