-
1
-
-
0038037236
-
Feedback inhibition by RALT controls signal output by the ErbB network
-
Anastasi, S., L. Florentino, M. Fiorini, R. Fraioli, G. Sala, L. Castellani, S. Alema, M. Alimandi, and O. Segatto. 2003. Feedback inhibition by RALT controls signal output by the ErbB network. Oncogene 22:4221-4234.
-
(2003)
Oncogene
, vol.22
, pp. 4221-4234
-
-
Anastasi, S.1
Florentino, L.2
Fiorini, M.3
Fraioli, R.4
Sala, G.5
Castellani, L.6
Alema, S.7
Alimandi, M.8
Segatto, O.9
-
2
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines, C. P., R. A. Kaiser, N. H. Purcell, N. S. Blair, H. Osinska, M. A. Hambleton, E. W. Brunskill, M. R. Sayen, R. A. Gottleib, G. W. Dorn II, J. Robbins, and J. D. Molkentin. 2005. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 434:658-662.
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottleib, R.A.9
Dorn II, G.W.10
Robbins, J.11
Molkentin, J.D.12
-
3
-
-
27544450547
-
Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved-like phenotype
-
Ballarò, C, S. Ceccarelli, C. Tiveron, L. Tatanelo, A. M. Salvatore, O. Segatto, and S. Alemà. 2005. Targeted expression of RALT in mouse skin inhibits epidermal growth factor receptor signalling and generates a Waved-like phenotype. EMBO Rep. 6:755-761.
-
(2005)
EMBO Rep.
, vol.6
, pp. 755-761
-
-
Ballarò, C.1
Ceccarelli, S.2
Tiveron, C.3
Tatanelo, L.4
Salvatore, A.M.5
Segatto, O.6
Alemà, S.7
-
4
-
-
0037092995
-
Diabetes and atherosclerosis: Epidemiology, pathophysiology and management
-
Beckman, J. A., M. A. Creager, and P. Libby. 2002. Diabetes and atherosclerosis: epidemiology, pathophysiology and management. JAMA 287:2570-2581.
-
(2002)
JAMA
, vol.287
, pp. 2570-2581
-
-
Beckman, J.A.1
Creager, M.A.2
Libby, P.3
-
5
-
-
0033520463
-
The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes
-
Bialik, S., V. L. Cryns, A. Drincic, S. Miyata, A. L. Wollowick, A. Srinivasan, and R. N. Kitsis. 1999. The mitochondrial apoptotic pathway is activated by serum and glucose deprivation in cardiac myocytes. Circ. Res. 85:403-414.
-
(1999)
Circ. Res.
, vol.85
, pp. 403-414
-
-
Bialik, S.1
Cryns, V.L.2
Drincic, A.3
Miyata, S.4
Wollowick, A.L.5
Srinivasan, A.6
Kitsis, R.N.7
-
6
-
-
0035321910
-
Molecular mechanisms of apoptosis in the cardiac myocyte
-
Bishopric, M. H., P. Andreka, T. Slepak, and K. A. Webster. 2001. Molecular mechanisms of apoptosis in the cardiac myocyte. Curr. Opin. Pharmacol. 1:141-150.
-
(2001)
Curr. Opin. Pharmacol.
, vol.1
, pp. 141-150
-
-
Bishopric, M.H.1
Andreka, P.2
Slepak, T.3
Webster, K.A.4
-
7
-
-
0032698075
-
Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms
-
Bonni, A., A. Brunet, A. E. West, S. R. Datta, M. A. Takasu, and M. E. Greenberg. 1999. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science 286:1358-1362.
-
(1999)
Science
, vol.286
, pp. 1358-1362
-
-
Bonni, A.1
Brunet, A.2
West, A.E.3
Datta, S.R.4
Takasu, M.A.5
Greenberg, M.E.6
-
8
-
-
23744468870
-
Gender-specific patterns of left ventricular and myocyte remodeling following myocardial infarction in mice deficient in the angiotensin II type 1a receptor
-
Bridgman, P., M. A. Aronovitz, R. Kakkar, M. I. Oliverio, T. M. Coffman, W. M. Rand, M. A. Konstant, M. E. Mendelsohn, and R. D. Patten. 2005. Gender-specific patterns of left ventricular and myocyte remodeling following myocardial infarction in mice deficient in the angiotensin II type 1a receptor. Am. J. Physiol. Heart Circ. Physiol. 289:H586-H592.
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.289
-
-
Bridgman, P.1
Aronovitz, M.A.2
Kakkar, R.3
Oliverio, M.I.4
Coffman, T.M.5
Rand, W.M.6
Konstant, M.A.7
Mendelsohn, M.E.8
Patten, R.D.9
-
9
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone, M. H., N. Roy, H. R. Stennicke, G. S. Salvesen, T. F. Franke, E. Stanbridge, S. Frisch, and J. C. Reed. 1998. Regulation of cell death protease caspase-9 by phosphorylation. Science 282:1318-1321.
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
10
-
-
0032190461
-
Endothelin stimulation of cardiomyocyte hypertrophy requires the SAPK pathway
-
Choukroun, G., J. V. Bonventre, J. M. Kyriakis, A. Rosenzweig, and T. Force. 1998. Endothelin stimulation of cardiomyocyte hypertrophy requires the SAPK pathway. J. Clin. Investig. 102:1311-1320.
-
(1998)
J. Clin. Investig.
, vol.102
, pp. 1311-1320
-
-
Choukroun, G.1
Bonventre, J.V.2
Kyriakis, J.M.3
Rosenzweig, A.4
Force, T.5
-
11
-
-
0036099675
-
ErbB2 is essential in the prevention of dilated cardiomyopathy
-
Crone, S. A., Y.-Y. Zhao, L. Fan, Y. Gu, S. Minamisawa, Y. Liu, K. L. Peterson, J. Chen, R. Kahn, G. Condorelli, J. Ross, Jr., K. R. Chien, and K.-F. Lee. 2002. ErbB2 is essential in the prevention of dilated cardiomyopathy. Nat. Med. 8:459-465.
-
(2002)
Nat. Med.
, vol.8
, pp. 459-465
-
-
Crone, S.A.1
Zhao, Y.-Y.2
Fan, L.3
Gu, Y.4
Minamisawa, S.5
Liu, Y.6
Peterson, K.L.7
Chen, J.8
Kahn, R.9
Condorelli, G.10
Ross Jr., J.11
Chien, K.R.12
Lee, K.-F.13
-
12
-
-
8844235617
-
The mitochondrial death pathway and cardiac myocyte apoptosis
-
Crow, M. T., K. Mani, Y. J. Nam, and R. N. Kitsis. 2004. The mitochondrial death pathway and cardiac myocyte apoptosis. Circ. Res. 95:957-970.
-
(2004)
Circ. Res.
, vol.95
, pp. 957-970
-
-
Crow, M.T.1
Mani, K.2
Nam, Y.J.3
Kitsis, R.N.4
-
13
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S. R., A. Brunet, and M. E. Greenberg. 1999. Cellular survival: a play in three Akts. Genes Dev. 13:2905-2927.
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
14
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., H. Reddy, M. Caivano, and P. Cohen. 2000. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351:95-105.
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
15
-
-
0033959317
-
Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes
-
de Moissac, D., R. M. Gurevich, H. Zheng, P. K. Singal, and L. A. Kirshenbaum. 2000. Caspase activation and mitochondrial cytochrome c release during hypoxia-mediated apoptosis of adult ventricular myocytes. J. Mol. Cell. Cardiol. 32:53-63.
-
(2000)
J. Mol. Cell. Cardiol.
, vol.32
, pp. 53-63
-
-
De Moissac, D.1
Gurevich, R.M.2
Zheng, H.3
Singal, P.K.4
Kirshenbaum, L.A.5
-
16
-
-
1342321750
-
PI 3-kinase, Akt and cell survival
-
Downward, J. 2004. PI 3-kinase, Akt and cell survival. Semin. Cell Dev. Biol. 15:177-182.
-
(2004)
Semin. Cell Dev. Biol.
, vol.15
, pp. 177-182
-
-
Downward, J.1
-
17
-
-
0030777768
-
Future horizons in cardiovascular molecular therapeutics
-
Dzau, V. J., G. H. Gibbons, M. Mann, and R. Braun-Dullaeus. 1997. Future horizons in cardiovascular molecular therapeutics. Am. J. Cardiol. 80:331-339.
-
(1997)
Am. J. Cardiol.
, vol.80
, pp. 331-339
-
-
Dzau, V.J.1
Gibbons, G.H.2
Mann, M.3
Braun-Dullaeus, R.4
-
18
-
-
0033796072
-
Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the Erb-B2 kinase domain
-
Fiorentino, L., C. Pertica, M. Fiorini, C. Talora, M. Crescenzi, L. Castellani, S. Alema, P. Benedetti, and O. Segatto. 2000. Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the Erb-B2 kinase domain. Mol. Cell. Biol. 20:7735-7750.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7735-7750
-
-
Fiorentino, L.1
Pertica, C.2
Fiorini, M.3
Talora, C.4
Crescenzi, M.5
Castellani, L.6
Alema, S.7
Benedetti, P.8
Segatto, O.9
-
19
-
-
0037107396
-
Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy
-
Goruppi, S., J. V. Bonventre, and J. M. Kyriakis. 2002. Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J. 21:5427-5436.
-
(2002)
EMBO J.
, vol.21
, pp. 5427-5436
-
-
Goruppi, S.1
Bonventre, J.V.2
Kyriakis, J.M.3
-
20
-
-
9644310269
-
Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes
-
Grazette, L. P., W. Boecker, T. Matsui, M. Semigran, T. L. Force, R. J. Hajjar, and A. Rosenzweig. 2004. Inhibition of ErbB2 causes mitochondrial dysfunction in cardiomyocytes. J. Am. Coll. Cardiol. 44:2231-2238.
-
(2004)
J. Am. Coll. Cardiol.
, vol.44
, pp. 2231-2238
-
-
Grazette, L.P.1
Boecker, W.2
Matsui, T.3
Semigran, M.4
Force, T.L.5
Hajjar, R.J.6
Rosenzweig, A.7
-
21
-
-
20444430478
-
Apoptotic pathways: Ten minutes to dead
-
Green, D. R. 2005. Apoptotic pathways: ten minutes to dead. Cell 121:671-674.
-
(2005)
Cell
, vol.121
, pp. 671-674
-
-
Green, D.R.1
-
22
-
-
0037446892
-
Stabilization of β-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth
-
Haq, S., A. Michael, M. Andreucci, K. Bhattacharya, P. Dotto, B. Walters, J. Woodgett, H. Kilter, and T. Force. 2003. Stabilization of β-catenin by a Wnt-independent mechanism regulates cardiomyocyte growth. Proc. Natl. Acad. Sci. USA 100:4610-4615.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4610-4615
-
-
Haq, S.1
Michael, A.2
Andreucci, M.3
Bhattacharya, K.4
Dotto, P.5
Walters, B.6
Woodgett, J.7
Kilter, H.8
Force, T.9
-
23
-
-
3943071150
-
Cytochrome c-mediated apoptosis
-
Jiang, X., and X. Wang. 2004. Cytochrome c-mediated apoptosis. Annu. Rev. Biochem. 73:87-106.
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
24
-
-
0036784463
-
Trastuzumab-associated cardiotoxicity
-
Keefe, D. 2002. Trastuzumab-associated cardiotoxicity. Cancer 95:1592-1600.
-
(2002)
Cancer
, vol.95
, pp. 1592-1600
-
-
Keefe, D.1
-
25
-
-
10944236872
-
Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1/erbB4 signaling
-
Kuramochi, Y., G. M. Cote, X. Guo, N. K. Lebrasseur, L. Cui, R. Liao, and D. B. Sawyer. 2004. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1/erbB4 signaling. J. Biol. Chem. 279:51141-51147.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51141-51147
-
-
Kuramochi, Y.1
Cote, G.M.2
Guo, X.3
Lebrasseur, N.K.4
Cui, L.5
Liao, R.6
Sawyer, D.B.7
-
26
-
-
0034625405
-
Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions such as diabetic nephropathy. Possible role in the response to persistent stress
-
Makkinje, A., D. A. Quinn, A. Chen, C. L. Cadilla, T. Force, J. V. Bonventre, and J. M. Kyriakis. 2000. Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions such as diabetic nephropathy. Possible role in the response to persistent stress. J. Biol. Chem. 275:17838-17847.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17838-17847
-
-
Makkinje, A.1
Quinn, D.A.2
Chen, A.3
Cadilla, C.L.4
Force, T.5
Bonventre, J.V.6
Kyriakis, J.M.7
-
27
-
-
0035902451
-
Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
-
Matsui, T., J. Tao, F. del Monte, K. H. Lee, L. Li, M. Picard, T. L. Force, T. F. Franke, R. J. Hajjar, and A. Rosenzweig. 2001. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation 104:330-335.
-
(2001)
Circulation
, vol.104
, pp. 330-335
-
-
Matsui, T.1
Tao, J.2
Del Monte, F.3
Lee, K.H.4
Li, L.5
Picard, M.6
Force, T.L.7
Franke, T.F.8
Hajjar, R.J.9
Rosenzweig, A.10
-
28
-
-
0005050791
-
Regulation of Gene 33 expression by insulin
-
B. Draznin and D. LeRoith (ed.). Humana Press, Totowa, NJ
-
Messina, J. L. 1994. Regulation of Gene 33 expression by insulin, p. 263-281. In B. Draznin and D. LeRoith (ed.), Molecular biology of diabetes. Part II. Insulin action, effects on gene expression and regulation, and glucose transport. Humana Press, Totowa, NJ.
-
(1994)
Molecular Biology of Diabetes. Part II. Insulin Action, Effects on Gene Expression and Regulation, and Glucose Transport
, pp. 263-281
-
-
Messina, J.L.1
-
29
-
-
0034517548
-
Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size
-
Miao, W., Z. Luo, R. N. Kitsis, and K. Walsh. 2000. Intracoronary, adenovirus-mediated Akt gene transfer in heart limits infarct size. J. Mol. Cell. Cardiol. 32:2397-2402.
-
(2000)
J. Mol. Cell. Cardiol.
, vol.32
, pp. 2397-2402
-
-
Miao, W.1
Luo, Z.2
Kitsis, R.N.3
Walsh, K.4
-
30
-
-
15844407874
-
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa, T., S. Shimizu, T. Watanabe, O. Yamaguchi, K. Otsu, H. Yamagata, H. Inohara, T. Kubo, and Y. Tsujimoto. 2005. Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 434:652-658.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamaguchi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
31
-
-
4944237210
-
17β-Estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-2-kinase/Akt signaling
-
Patten, R. D., I. Pourati, M. J. Aronovitz, J. Baur, F. Celestin, X. Chen, A. Michael, A. Haq, S. Nuedling, C. Grohe, T. Force, M. E. Mendelsohn, and R. H. Karas. 2004. 17β-Estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-2-kinase/Akt signaling. Circ. Res. 95:692-699.
-
(2004)
Circ. Res.
, vol.95
, pp. 692-699
-
-
Patten, R.D.1
Pourati, I.2
Aronovitz, M.J.3
Baur, J.4
Celestin, F.5
Chen, X.6
Michael, A.7
Haq, A.8
Nuedling, S.9
Grohe, C.10
Force, T.11
Mendelsohn, M.E.12
Karas, R.H.13
-
32
-
-
0035952645
-
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
-
Pierce, K. L., L. M. Luttrell, and R. J. Lefkowitz. 2001. New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 20:1532-1539.
-
(2001)
Oncogene
, vol.20
, pp. 1532-1539
-
-
Pierce, K.L.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
34
-
-
1842830427
-
Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes
-
Shiraishi, I., J. Melendez, Y. Ahn, M. Skavdahl, E. Murphy, S. Welch, E. Schaefer, K. Walsh, A. Rosenzweig, D. Torella, D. Nurzynska, J. Kajstura, A. Leri, P. Anversa, and M. A. Sussman. 2004. Nuclear targeting of Akt enhances kinase activity and survival of cardiomyocytes. Circ. Res. 94:884-891.
-
(2004)
Circ. Res.
, vol.94
, pp. 884-891
-
-
Shiraishi, I.1
Melendez, J.2
Ahn, Y.3
Skavdahl, M.4
Murphy, E.5
Welch, S.6
Schaefer, E.7
Walsh, K.8
Rosenzweig, A.9
Torella, D.10
Nurzynska, D.11
Kajstura, J.12
Leri, A.13
Anversa, P.14
Sussman, M.A.15
-
35
-
-
0037418528
-
The many forks in FOXO's road
-
[Online.] doi:10.1126/stke.2003.172.re5
-
Tran, H., A. Brunei, E. C. Griffith, and M. E. Greenberg. 2003. The many forks in FOXO's road. Sci. STKE 2003:RE5. [Online.] doi:10.1126/stke.2003.172. re5.
-
(2003)
Sci. STKE
, vol.2003
-
-
Tran, H.1
Brunei, A.2
Griffith, E.C.3
Greenberg, M.E.4
-
36
-
-
0035347550
-
Coronary artery disease: Pathogenesis and acute coronary syndromes
-
Worthley, S. G., J. I. Osende, G. Helft, J. J. Badimon, and V. Fuster. 2001. Coronary artery disease: pathogenesis and acute coronary syndromes. Mt. Sinai J. Med. 68:167-181.
-
(2001)
Mt. Sinai J. Med.
, vol.68
, pp. 167-181
-
-
Worthley, S.G.1
Osende, J.I.2
Helft, G.3
Badimon, J.J.4
Fuster, V.5
-
37
-
-
13244283225
-
Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone induced suppression of EGF function
-
Xu, D., A. Makkinje, and J. M. Kyriakis. 2005. Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone induced suppression of EGF function. J. Biol. Chem. 280:2924-2933.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2924-2933
-
-
Xu, D.1
Makkinje, A.2
Kyriakis, J.M.3
-
38
-
-
23844443142
-
Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease
-
Zhang, Y.-W., Y. Su, N. Lanning, P. J. Swiatek, R. T. Bronson, R. Sigler, R. W. Martin, and G. F. Vande Woude. 2005. Targeted disruption of Mig-6 in the mouse genome leads to early onset degenerative joint disease. Proc. Natl. Acad. Sci. USA 102:11740-11745.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 11740-11745
-
-
Zhang, Y.-W.1
Su, Y.2
Lanning, N.3
Swiatek, P.J.4
Bronson, R.T.5
Sigler, R.6
Martin, R.W.7
Vande Woude, G.F.8
|