(5R)-5-Hydroxytriptolide attenuated collagen-induced arthritis in DBA/1 mice via suppressing interferon-γ production and its related signaling

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 1, 2006, Pages 35-44

  Zhou, Ru ^a   Tang, Wei ^a   Ren, Yong Xin ^a   He, Pei Lan ^a   Zhang, Fan ^a   Shi, Li Ping ^a   Fu, Yun Feng ^a   Li, Yuan Chao ^a   Ono, Shiro ^b   Fujiwara, Hiromi ^b   Yang, Yi Fu ^a   Zuo, Jian Ping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYTRIPTOLIDE; ANTIBODY; ARGINASE; CHEMOKINE; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; COLLAGEN; CYTOKINE; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERFERON REGULATORY FACTOR 1; INTERLEUKIN 12 RECEPTOR BETA2; INTERLEUKIN 2; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; NITRIC OXIDE; STAT1 PROTEIN; STAT4 PROTEIN; T BOX TRANSCRIPTION FACTOR; TRIPTOLIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTHRITIS; ARTHROPATHY; ARTICLE; CELL SELECTION; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; FLUORESCENCE; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSCRIPTION; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGLOBULIN BLOOD LEVEL; INCIDENCE; LYMPHOCYTE PROLIFERATION; MALE; MEDICAL ASSESSMENT; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; SCORING SYSTEM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; DITERPENES; INTERFERON TYPE II; MICE; MICE, INBRED DBA; NITRIC OXIDE SYNTHASE; SIGNAL TRANSDUCTION;

EID: 33745263975     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.101113     Document Type: Article

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