Inhibition of type II collagen-induced arthritis in rats by triptolide

International Journal of Immunopharmacology

Volumn 20, Issue 8, 1998, Pages 389-400

  Gu, Wen Zhen ^a   Brandwein, Sydney R ^a,b  

^a ABBOTT LABORATORIES   (United States)

^b ADVOCATE CHRIST MEDICAL CENTER   (United States)

Author keywords

Collagen induced arthritis; Immunosuppression; In vivo animal models; Inflammation; Rheumatoid arthritis

Indexed keywords

COLLAGEN TYPE 2; TRIPTOLIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRITIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HISTOPATHOLOGY; HUMORAL IMMUNITY; IMMUNOMODULATION; INCIDENCE; MEDICINAL PLANT; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; T LYMPHOCYTE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES; ARTHRITIS, EXPERIMENTAL; CATTLE; COLLAGEN; DITERPENES; FEMALE; HINDLIMB; HYPERSENSITIVITY, DELAYED; IMMUNOSUPPRESSIVE AGENTS; PHENANTHRENES; PILOT PROJECTS; RATS; RATS, INBRED LEW;

EID: 0032437442     PISSN: 01920561     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0192-0561(98)00035-6     Document Type: Article

References (28)

1. Banerjee, S., Haqqi, T.M., Luthra, H.S., Stuart, J.M., David, C.S., 1988a. Possible role of Vβ T cell receptor genes in susceptibility to collagen-induced arthritis in mice. J. Exp. Med. 167, 832-839.
2. Banerjee, S., Wei, B.Y., Hillman, K., Luthra, H.S., David, C.S., 1988b. Immunosuppression of collagen-induced arthritis in mice with an anti-IL 2 receptor antibody. J. Immunol. 141, 1150-1154.
3. Brahn, E., Trentham, D.E., 1984. Effect of antithymocyte serum on collagen arthritis in rats: evidence that T cells are involved in its pathogenesis. Cell. Immunol. 86, 421-428.
4. Caulfield, J.P., Hein, A., Dynesius-Trentham, R., Trentham, D.E., 1982. Morphologic demonstration of two stages in the development of type II collagen-induced arthritis. Lab. Invest. 46, 321-343.
5. Chen, K., Shi, Q., Fujioka, T., Zhang, D.C., Hu, C.Q., Jin, J.Q., Kilkuskie, R.E., Lee, K.H., 1992a. Anti-AIDS agents, 4. Tripterifordin, a novel anti-HIV principle from Tripterygium wilfordii: Isolation and structural elucidation. J. Natural. Prod. 55, 88-92.
6. Chen, K., Shi, Q., Kashiwada, Y., Zhang, D.C., Hu, C.Q., Jin, J.Q., Nozaki, H., Kilkuskie, R.E., Tramontano, E., Cheng, Y.C., McPhail, D.R., McPhail, A.T., Lee, K.H., 1992b. Anti-AIDS agents, 6. Salaspermic acid, anti-HIV principle from Tripterygium wilfordii, and the structure-activity correlation with its related compounds. J. Natural. Prod. 55, 340-346.
7. Colorado, A., Slama, J.T., Stavinoha, W.B., 1991. A new method for measuring auricular inflammation in the mouse. J. Pharmac. Meth. 26, 73-77.
8. Cremer, M., 1988. Type II collagen-induced arthritis in rats. In: Greenwald, R.A., Diamond, H.S. (Eds.), Handbook of Animal Models for the Rheumatic Diseases, Vol. 1, 1st edition, pp. 17-27, CRC Press, Boca Raton, FL.
9. Durie, F.H., Fava, R.A., Foy, T.M., Aruffo, A., Ledbetter, J.A., Noelle, R.J., 1993. Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. Science 261, 1328-1330.
10. Glantz, S.A., 1981. How to analyze rates and proportions. In: Primer of Biostatistics, pp. 94-128, McGraw-Hill, New York.
11. Gu, W.Z., Banerjee, S., Rauch, J., Brandwein, S.R., 1992a. Suppression of renal disease and arthritis and prolongation of survival in MRL-lpr mice treated with an extract of Tripterygium wilfordii Hook f. Arthritis Rheum. 35, 1381-1386.
12. Gu, W.Z., Brandwein, S.R., Banerjee, S., 1992b. Inhibition of type II collagen induced arthritis in mice by an immunosuppressive extract of Tripterygium wilfordii Hook f. J. Rheumatol. 19, 682-688.
13. Gu, W.Z., Chen, R., Brandwein, S., McAlpine, J., Burres, N., 1995. Isolation, purification, and characterization of immunosuppressive compounds from Tripterygium: triptolide and tripdiolide. Int. J. Immunopharmac. 17, 351-356.
14. Helfgott, S.M., Dynesius-Trentham, R.A., Brahn, E., Trentham, D.E., 1985. An arthritogenic lymphokine in the rat. J. Exp. Med. 162, 1531-1545.
15. Holmdahl, R., Jonsson, R., Larsson, P., Klareskog, L., 1988. Early appearance of activated CD4+T lymphocytes and class I antigen-expressing cells in joints of DBA/1 mice immunized with type II collagen. Lab. Invest. 58, 53-60.
16. Holmdahl, R., Klareskog, L., Rubin, K., Larsson, E., Wigzell, H., 1985a. T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T cell lines and clones. Scand. J. Immunol. 22, 295-306.
17. Holmdahl, R., Rubin, K., Klareskog, L., Dencker, L., Gustafson, G., Larsson, E., 1985b. Appearance of different lymphoid cells in synovial tissue and in peripheral blood during the course of collagen II-induced arthritis in rats. Scand. J. Immunol. 21, 197-204.
18. Klareskog, L., Holmdahl, R., Larsson, E., Wigzell, H., 1983. Role of T lymphocytes in collagen II induced arthritis in rats. Clin. Exp. Immunol. 51, 117-125.
19. Kupchan, S.M., Court, W.A., Daily Jr., R.G., Gilmore, C.J., Bryan, R.F., 1972. Triptolide and tripdiolide, novel anti-leukemic diterpenoid triepoxides from Tripterygium wilfordii. J. Am. Chem. Soc. 94, 7194-7195.
20. Kutney, J.P., Hewitt, G.M., Kurihara, T., Salisbury, P.J., Sindelar, R.D., Stuart, K.L., Townsley, P.M., Chalmers, W.T., Jacoli, G.G., 1981. Cytotoxic diterpenes triptolide, tripdiolide, and cytotoxic triterpenes from tissue cultures of Tripterygium wilfordii. Can. J. Chem. 59, 2677-2683.
21. Kutney, J.P., Hewitt, G.M., Lee, G., Piotrowska, K., Roberts, M., Rettig, S.J., 1992. Studies with tissue cultures of the Chinese herbal plant, Tripterygium wilfordii. Isolation of metabolites of interest in rheumatoid arthritis, immunosuppression, and male contraceptive activity. Can. J. Chem. 70, 1455-1480.
22. Stuart, J.M., Cremer, M.A., Townes, A.S., Kang, A.H., 1982. Type II collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis. J. Exp. Med. 155, 1-16.
23. Takaishi, Y., Shishido, K., Wariishi, N., Shibuya, M., Goto, K., Kido, M., Takai, M., Ono, Y., 1992. Triptoquinone A and B, novel interleukin 1 inhibitors from Tripterygium wilfordii var regelii. Tetrahedron Lett. 33, 7177-7180.
24. Tao, X.L., Cai, J., Davis, L.S., Lipsky, P.E., 1992. Suppressive effect of triptolide on in vitro immune function of human peripheral blood T cells (abstract). Arthritis Rheum. 35 (Suppl. 9), S129.
25. Tao, X., Davis, L.S., Lipsky, P.E., 1991. Effect of an extract of the Chinese herbal remedy Triptergium wilfordii Hook f on human immune responsiveness. Arthritis Rheum. 34, 1274-1281.
26. Trentham, D.E., Townes, A.S., Kang, A.H., 1978. Humoral and cellular sensitivity to collagen in type II collagen-induced arthritis in rats. J. Clin. Invest. 61, 89-96.
27. Wenyan, X., Jiarun, Z., Xueyu, L., 1985. Tripterygium in dermatologic therapy. Int. J. Dermatol. 24, 152-157.
28. Yang, S.X., Gao, H.L., Xie, S.S., Zhang, W.R., Long, Z.Z., 1992. Immunosuppression of triptolide and its effect on skin allograft survival. Int. J. Immunopharmac. 14, 963-969.