CD4+ T-cell response to mitochondrial cytochrome b in human melanoma

Cancer Research

Volumn 66, Issue 11, 2006, Pages 5919-5926

  Voo, Kui Shin ^a,b   Zeng, Gang ^c   Mu, Jian Bing ^d   Zhou, Juhua ^e   Su, Xin Zhuan ^d   Wang, Rong Fu ^a,b  

^a CENTER FOR CELL AND GENE THERAPY   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME B; EPITOPE; HLA DR1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MESSENGER RNA; RHODAMINE 6G; TUMOR ANTIGEN;

ARTICLE; CARCINOGENESIS; CD4+ T LYMPHOCYTE; CELL DAMAGE; CONTROLLED STUDY; CYTOPLASM; DRUG INHIBITION; GENE MUTATION; GENETIC TRANSCRIPTION; HETEROPLASMY; HUMAN; HUMAN CELL; IMMUNOSURVEILLANCE; MELANOMA; MELANOMA CELL; MITOCHONDRION; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; RNA TRANSLATION; TUMOR GROWTH;

AMINO ACID SEQUENCE; BASE SEQUENCE; CD4-POSITIVE T-LYMPHOCYTES; CYTOCHROMES B; DNA, MITOCHONDRIAL; EPITOPES, T-LYMPHOCYTE; HLA-DR1 ANTIGEN; HUMANS; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; MUTATION; OPEN READING FRAMES;

EID: 33745256026     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-05-4574     Document Type: Article

References (42)

1. + T cells in antitumor immunity. Trends Immunol 2001;22:269-76.
2. + T lymphocytes. Nature 2003;421:852-6.
3. Shedlock DJ, Shen H. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science 2003;300:337-9.
4. Sun JC, Bevan MJ. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003;300:339-42.
5. + T cells in the control of mouse Burkitt lymphoma in vivo. J Clin Invest 2004;114:542-50.
6. + T cell-dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells. J Clin Invest 2002;109:1463-70.
7. Wang RF, Wang X, Atwood AC, Topalian SL, Rosenberg SA. Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. Science 1999;284:1351-4.
8. Schultz-Thater E, Noppen C, Gudat F, et al. NY-ESO-1 tumour associated antigen is a cytoplasmic protein detectable by specific monoclonal antibodies in cell lines and clinical specimens. Br J Cancer 2000;83:204-8.
9. Raposo G, Tenza D, Murphy DM, Berson JF, Marks MS. Distinct protein sorting and localization to premelanosomes, melanosomes, and lysosomes in pigmented melanocytic cells. J Cell Biol 2001;152:809-24.
10. + T cells: its role in extracellular matrix formation and tumor metastasis. J Exp Med 2002;195:1397-406.
11. Shimoda S, Van de Water J, Ansari A, et al. Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis. J Clin Invest 1998;102:1831-40.
12. Matsumura S, Kita H, He XS, et al. Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis. Hepatology 2002;36:1125-34.
13. + cytolytic T lymphocytes. J Immunol 2000;164:1669-80.
14. Sasada T, Ghendler Y, Neveu JM, Lane WS, Reinherz EL. A naturally processed mitochondrial self-peptide in complex with thymic MHC molecules functions as a selecting ligand for a viral-specific T cell receptor. J Exp Med 2001;194:883-92.
15. Berg RE, Princiotta MF, Irion S, Moticka JA, Dahl KR, Staerz UD. Positive selection of an H2-3 restricted T cell receptor. Immunity 1999;11:33-3.
16. Poetsch M, Dittberner T, Petersmann A, Woenckhaus C. Mitochondrial DNA instability in malignant melanoma of the skin is mostly restricted to nodular and metastatic stages. Melanoma Res 2004;14:501-8.
17. + T cells. Cancer Res 2002;62:7195-9.
18. Wang RF, Johnston SL, Zeng G, Topalian SL, Schwartzentruber DJ, Rosenberg SA. A breast and melanoma-shared tumor antigen: T cell responses to antigenic peptides translated from different open reading frames. J Immunol 1998;161:3598-606.
19. Wang RF, Appella E, Kawakami Y, Kang X, Rosenberg SA. Identification of TRP-2 as a human tumor antigen recognized by cytotoxic T lymphocytes. J Exp Med 1996;184:2207-16.
20. Mu J, Duan J, Makova KD, et al. Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum. Nature (Lond) 2002;418:323-6.
21. Aronson NN, Jr., Touster O. Isolation of rat liver plasma membrane fragments in isotonic sucrose. Methods Knzymol 1974;31:90-102.
22. Rubinson DA, Dillon CP, Kwiatkowski A, et al. A lenti virus-based system to functionally silence genes in primary mammalian cells, stem cells, and transgenic mice by RNA interference. Nat Genet 2003;33:401-6.
23. Rosenberg SA, Yannelli JR, Yang JC, et al. Treatment of patients with met astatic melanoma with autologous tumor-infiltrating lymphocytes and interleukin 2. J Natl Cancer Inst 1994;86:1159-66.
24. + T lymphocytes. J Exp Med 2004;199:459-70.
25. Marin Garcia J, Hu Y, Ananthakrishnan R, Pierpont ME, Pierpont GL, Goldenthal MJ. A point mutation in the cytb gene of cardiac mtDNA associated with complex III deficiency in ischemic cardiomyopathy. Biochem Mol Biol Int 1996;40:487-95.
26. Andreu AL, Hanna MG, Reichmann H, et al. Exercise intolerance due to mutations in the cytochrome b gene of mitochondrial DNA. N Engl J Med 1999;341:1037-41.
27. Nekhaeva E, Bodyak ND, Kraytsberg Y, et al. Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues. Proc Natl Acad Sci USA 2002;99:5521-6.
28. Coller HA, Khrapko K, Bodyak ND, Nekhaeva F, Herrero-Jimenez P, Thilly WG. High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat Genet 2001;28:147-50.
29. Polyak K, Li Y, Zhu H, et al. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat Genet 1998;20:291-3.
30. Khrapko K, Coller HA, Andre PC, Li XC, Hanekamp JS, Thilly WG. Mitochondrial mutational spectra in human cells and tissues. Proc Natl Acad Sci U S A 1997;94:13798-803.
31. Borisov VB. Defects in mitochondrial respiratory complexes III and IV and human pathologies. Mol Aspects Med 2002;23:385-412.
32. Andreu AL, Bruno C, Dunne TC, et al. A nonsense mutation (G15059A) in the cytochrome b gene in a patient with exercise intolerance and myoglobinuria. Ann Neurol 1999;45:127-30.
33. Johns DR, Neufeld MJ. Cytochrome b mutations in Leber hereditary optic neuropathy. Biochem Biophys Res Commun 1991;181:1358-64.
34. De Coo IF, Renier WO, Ruitenbcek W, et al. A 4-base pair deletion in the mitochondrial cytochrome h gene associated with parkinsonism/MELAS overlap syndrome. Ann Neurol 1999;45:130-3.
35. Valnot I, Kassis J, Chretien D, et al. A mitochondrial cytochrome b mutation but no mutations of nuclearly encoded subunits in ubiquinol cytochrome c reductase (complex III) deficiency. Hum Genet 1999;104:460-6.
36. Fisher N, Meunier B. Effects of mutations in mitochondrial cytochrome b in yeast and man. Deficiency, compensation, and disease. Eur J Biochem 2001;268:1155-62.
37. Pakendorf B, Stoneking M. Mitochondrial DNA and human evolution. Annu Rev Genomics Hum Genet 2005;6:165-83.
38. Wallace DC. Mitochondrial diseases in man and mouse. Science 1999;283:1482-8.
39. Holman CD, Armstrong BK, Heenan PJ. A theory of the etiology and pathogenesis of human cutaneous malignant melanoma. J Natl Cancer Inst 19883;71:651-6.
40. Whiteman DC, Whiteman CA, Green AC. Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies. Cancer Causes Control 2001;12:69-821.
41. Wallace DC. Mouse models for mitochondrial disease. Am J Med Genet 2001;106:71-93.
42. Eng C, Kiuru M, Fernandez MJ, Aaltonen LA. A role for mitochondrial enzymes in inherited neoplasia and beyond. Nat Rev Cancer 2003;3:193-202.