Blockade of angiogenesis by small molecule antagonists to protease-activated receptor-1: Association with endothelial cell growth suppression and induction of apoptosis

Journal of Pharmacology and Experimental Therapeutics

Volumn 318, Issue 1, 2006, Pages 246-254

  Zania, Panagiota ^a   Kritikou, Sosanna ^a   Flordellis, Christodoulos S ^a   Maragoudakis, Michael E ^a   Tsopanoglou, Nikos E ^a  

^a UNIVERSITY OF PATRAS   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

LIPOCORTIN 5; MATRIGEL; MITOGEN ACTIVATED PROTEIN KINASE; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROPIDIUM IODIDE; PROTEINASE ACTIVATED RECEPTOR 1; RECEPTOR BLOCKING AGENT; RWJ 56110; SCH 79797; THROMBIN; THYMIDINE; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CAPILLARY; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL GROWTH; CELL PROLIFERATION; CHORIOALLANTOIS; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; EMBRYO CELL; ENDOTHELIUM CELL; GENE INDUCTION; HUMAN; HUMAN CELL; IN VIVO STUDY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; STAINING;

ANGIOGENESIS INHIBITORS; ANIMALS; APOPTOSIS; CHICK EMBRYO; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; NEOVASCULARIZATION, PHYSIOLOGIC; PYRROLES; QUINAZOLINES; RECEPTOR, PAR-1;

EID: 33745231782     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.105.099069     Document Type: Article

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