2D QSAR of PPARγ agonist binding and transactivation

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 15, 2006, Pages 5178-5195

  Rücker, Christoph ^a   Scarsi, Marco ^a   Meringer, Markus ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b Kiadis BV   (Netherlands)

Author keywords

2D QSAR; PPAR agonists; Type 2 diabetes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; FATTY ACID DERIVATIVE; INDOLE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA AGONIST; PHENOXYACETIC ACID DERIVATIVE; PROPIONIC ACID DERIVATIVE; TYROSINE DERIVATIVE; DRUG DERIVATIVE; FATTY ACID; LIGAND; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TYROSINE;

ARTICLE; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TRANSACTIVATION; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; DRUG EFFECT; DRUG POTENTIATION; GENETICS; HUMAN;

BINDING SITES; COMPUTER SIMULATION; DRUG DESIGN; FATTY ACIDS; HUMANS; INDOLES; LIGANDS; MOLECULAR STRUCTURE; PPAR GAMMA; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLIDINEDIONES; TRANS-ACTIVATION (GENETICS); TYROSINE;

EID: 33745172856     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.04.005     Document Type: Article

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